Basic Information

Gene Symbol
-
Assembly
GCA_963662085.1
Location
OY759205.1:2704164-2711616[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.29 21 6.4 0.8 1 23 286 308 286 308 0.96
2 9 0.77 57 5.1 0.1 2 23 376 398 375 398 0.91
3 9 0.022 1.6 9.9 1.0 1 23 402 424 402 424 0.96
4 9 0.0016 0.12 13.5 1.6 1 23 430 453 430 453 0.85
5 9 0.015 1.1 10.4 1.1 2 23 460 482 459 482 0.91
6 9 1.5e-06 0.00011 23.0 1.3 1 23 488 511 488 511 0.98
7 9 5.9e-05 0.0043 18.0 1.8 1 23 517 539 517 539 0.98
8 9 1.4e-06 0.00011 23.1 3.4 1 23 545 567 545 567 0.99
9 9 1.6e-06 0.00012 23.0 2.0 1 23 573 595 573 596 0.96

Sequence Information

Coding Sequence
ATGAGTGTAACTATTACGAAAACCAATGGACCTATTATAAACCCAGCATTGTGCAGATGTTGTAgggctattaaaaaatgtagaaCACTTACTGCTGAATACACTTGGCAGGAAGAGAAGGAGGTTTATGCAGACATGGTTATGGATTGTTTCGGGATTTTGCTCTCCCACGTAGATGACAATGAGAAGGACTGTGGCGTGTGTGCAACCTGCGTGGTGCGACTGCGTGACGCGAGTGCATTTCGCCGCCAAGTGCTGCAGTGTGAAGAACTGTTCCTGAATGCCAAACTGCAGCCCGACAAGGAACTTGaagtaaaAATTACGCGGCATCTGGACATTGATCTCAAAATTGAACCAAAAGACGACGTTGCAGAGGATGATGACCTGTTTTTGAATTTCGCTAGTGCGGCCCCTATCGACGACGAACCAAAACCGCCAGCAGTCTTCGAGGGATGTGACAGTAAACCGCCCCCAGAAATTGATATGAAAGATAAAATCGAGAAACCCGAGCCTGATGAGAAGGATGAGCCGATGAACTTCGAAGGCGCTGACGATGACAGAGACAGTGATTGGTCGGCCTCGTCATCCGACTCTGATAAACCGCTGAAGCGAAAGAAAAAAGTAGAGAAGAAGGCGAAAACTAGTAACGGCAAGGTCACGAAGAAGAAGGTTAAGACGCTGAAAGAAAAAGTTGTAAAGAAAAAAGCAGatacaaaaaaactgaaatCTCCAAAGAAGCCCCCAGTCGAAAAGAAACCCAACCCCGACAGAGATCTAGACTGCATGTCCGAAGAGAATCTCCTCACAATCATCCAATACTCATACGTCTGCCCTTTCAAGAACAGGAGGAACAACTACTATTGCTTTTATTGCAAGGATTATTATCCAAAACCTGAAGACTTGAGAGATCACACAGTATCTCACGACACGAAGCCCTTCCAAATCCTAATGGGCTACAAGAAAATGCCCAAGTTAGACATAACTCGAATAGACTGCAGATTGTGCCCAGTGAAAATTGACGATCTAAACGTATTCAAACAGCATATAGACAACGTTCATGGTAAGAAAATATACTTTGAAGCGCCGGATAAGATGCTTCTCTTCCGCCTCACTTGGAACGATTTGGTCTGTGTCGTTTGCAGCGATGTCTTCGAAGATTTCAACACGCTGAGCACTCACATGATAGATACGCATTTCAGTAATTTCACCTGTGATATCTGTGGGATGTGTTTCTTAGAGAAACCGAGATTAGATGCCCATTTAAAGAGACATAAAGACGATGAGAAACATACCTGCGAAATATGCGGTAAAGTCTTCAAATCCAACCATTACAAAGACATGCATGTCGATATAGTGCATAAACGTAAAGCTATAATTCGTTGTCCGAAATGCGACGAGTGTTTCATGTCGTACGCattgaaaaacaaacatttgaccGAAGCGCACGGCCAGAAGCGGACGTACCCTTGCAATTTGTGCGACAAAGTTTACAATAGGCAAAAAACTTTGACCGAGCATCAAAGACGTAATCATCAGAAGGTTATGAAACATCAATGTGAATACTGTGATCAAAGGTTCTATTTGCCATCGAGGTTGAAAGAGCATATGGCGACGCATACAGGAGAAAGGAATTTCCGATGTGAGCATTGTGATAAGAGTTATCCACGTCTTAAGTCTTTACAGTATCACATACGAACGCATACTAACGATAGGAGATTCCGGTGTCATATTTGCGGTCAAGGGTTCATCCAAAATCCTAGTTTGAAAGCGCATATTAAAAGCCACCATCCCGAGTGTGAGGTCGACTTTTTGTATGacaataattttaggaaattccaATAA
Protein Sequence
MSVTITKTNGPIINPALCRCCRAIKKCRTLTAEYTWQEEKEVYADMVMDCFGILLSHVDDNEKDCGVCATCVVRLRDASAFRRQVLQCEELFLNAKLQPDKELEVKITRHLDIDLKIEPKDDVAEDDDLFLNFASAAPIDDEPKPPAVFEGCDSKPPPEIDMKDKIEKPEPDEKDEPMNFEGADDDRDSDWSASSSDSDKPLKRKKKVEKKAKTSNGKVTKKKVKTLKEKVVKKKADTKKLKSPKKPPVEKKPNPDRDLDCMSEENLLTIIQYSYVCPFKNRRNNYYCFYCKDYYPKPEDLRDHTVSHDTKPFQILMGYKKMPKLDITRIDCRLCPVKIDDLNVFKQHIDNVHGKKIYFEAPDKMLLFRLTWNDLVCVVCSDVFEDFNTLSTHMIDTHFSNFTCDICGMCFLEKPRLDAHLKRHKDDEKHTCEICGKVFKSNHYKDMHVDIVHKRKAIIRCPKCDECFMSYALKNKHLTEAHGQKRTYPCNLCDKVYNRQKTLTEHQRRNHQKVMKHQCEYCDQRFYLPSRLKEHMATHTGERNFRCEHCDKSYPRLKSLQYHIRTHTNDRRFRCHICGQGFIQNPSLKAHIKSHHPECEVDFLYDNNFRKFQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00702321;
90% Identity
iTF_00704378;
80% Identity
-