Basic Information

Gene Symbol
ZIPIC
Assembly
GCA_963662085.1
Location
OY759187.1:465506-466900[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 6.6e-05 0.0049 17.9 0.1 2 23 153 174 152 174 0.96
2 11 7.2e-05 0.0053 17.8 1.0 1 23 180 203 180 203 0.96
3 11 3.3e-06 0.00025 22.0 0.1 1 23 211 233 211 233 0.98
4 11 0.00012 0.0092 17.0 1.3 1 23 239 261 239 261 0.98
5 11 0.00057 0.042 14.9 2.8 1 23 267 289 267 289 0.95
6 11 2.1e-05 0.0016 19.4 0.6 1 23 295 317 295 317 0.98
7 11 1.4e-07 1e-05 26.3 2.4 1 23 323 346 323 346 0.98
8 11 7.8 5.7e+02 1.9 2.8 5 19 352 366 350 370 0.92
9 11 0.91 67 4.9 1.3 2 23 377 399 376 399 0.92
10 11 0.11 8.4 7.7 0.2 1 23 405 430 405 430 0.96
11 11 0.00026 0.019 16.0 0.6 1 23 436 459 436 459 0.92

Sequence Information

Coding Sequence
atggaTTTTAATCTGTGTCGGTTATGCTATGATAGAGAAGCTGCTATATGCATTTTCCAAAGTGGAAGTGCTGAGCAAGTTGTCactaaaatattgtattgttgtaAATCTGTGAAGATACAAGAGAAGGATGGCTTACCGGGGAATATATGCAACGTCTGCGACCGGGACCTCGAATTCTGTTACCAGTTCTTGCAGCAGTGCGAGGCCTCAGATGAGAAACTGCGATTACTTAGTAAGTCACCATCTCTTAGTCAGCAGTACATAACCAAAACAGAGGTCAAGAATGAAGGCGAAGACCTCGATGACTATGCGAGCCACAATACAGacgaaatcaaattatttcccCTGGACATAAAACCAGACGCATTCCAATCAGAAGAACATGCAGATTTGGGGAAATTCCACGTCAGAAAACCGCgaaggaaacaaataaaatacataaaggAAGATCTAAACTGTGCAGTTTGCAGTCGCGCGTGCGCCAGCGCCTCCGCGCTCGCTGCGCACATGCGCACGCACTCCGGGGAGAAGCCCTTCCAGTGCGCCGCCTGCGACAAGCGGTACAAGGACAGTGGAACGCTGAAGAGGCACACGGAGAGAAACCACCTTGCACATCGGGAAAGAAGGTTCATCTGCGAGAACTGCGGGAAAGGGTTCTATTCCAAAAGCGACATAGTGATCCACATGAGAGTCCACACCGGTGAAACTCCATATTCATGTCCCATCTGTCAGTCCAGGTTCACTCAGATGAGCGCTATGCTGAGGCACAAGCGACGTCACGCGGAGGATAAGACGCACGCGTGCGCCACGTGCGGCAAGTCCTTCTGGACCAAGGAGGAGCTGAAGAAGCATCACAGCGTGCACGACGATGCGCGCCGCTTCCAATGCCCCCTCTGCAGCGTGCTGTTCAAGCAGAAGAGCAACATCAAGAAGCACATGGCCATCCACATCGACCCCAACAGATATGTCTGCAACCACTGCGGGAAAACATTCAATGTCAAAGGAAACCTTAAATCACACATTAACAGAAGGCATTCTGAGAAGTCAGGCTACTGCACAATCTGCTGCAAAAATGTGTCCAACTTTGAGCACCACTCGTGGAAGCACACGGGGAAGAGACCCCTCAAATGTGAATTCTGTCCAAGCAGCTTTTGTGAAATGAGAGCTTTGGGTCTGCACATCAACTTTAAGCACAAAAAGACTGAGAGGTTCAAGTGCAGCATGGAAGGCTGCACCCTTGGCTTTCCATCTAAACCAATGATGATGTACCACATCGCTAGGTTCCATGACATGCAGACTCCGTACCCTTGTGACCGCTGCCCGAGAGGGTTTTACAGGAAGAATGACTTATCCAGGCATAAAATAGGTACTCATAAAGAAAGACTACTGTAG
Protein Sequence
MDFNLCRLCYDREAAICIFQSGSAEQVVTKILYCCKSVKIQEKDGLPGNICNVCDRDLEFCYQFLQQCEASDEKLRLLSKSPSLSQQYITKTEVKNEGEDLDDYASHNTDEIKLFPLDIKPDAFQSEEHADLGKFHVRKPRRKQIKYIKEDLNCAVCSRACASASALAAHMRTHSGEKPFQCAACDKRYKDSGTLKRHTERNHLAHRERRFICENCGKGFYSKSDIVIHMRVHTGETPYSCPICQSRFTQMSAMLRHKRRHAEDKTHACATCGKSFWTKEELKKHHSVHDDARRFQCPLCSVLFKQKSNIKKHMAIHIDPNRYVCNHCGKTFNVKGNLKSHINRRHSEKSGYCTICCKNVSNFEHHSWKHTGKRPLKCEFCPSSFCEMRALGLHINFKHKKTERFKCSMEGCTLGFPSKPMMMYHIARFHDMQTPYPCDRCPRGFYRKNDLSRHKIGTHKERLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00698540;
90% Identity
iTF_00700356;
80% Identity
-