Basic Information

Insect: Eupithecia abbreviata
Gene Symbol: zfh1
Assembly: GCA_943735975.1
Location: CALSER010000063.1:1192346-1203117[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.042 2.5 9.0 0.1 1 23 105 127 105 127 0.95

2 8 4.5e-06 0.00026 21.5 3.0 1 23 138 160 138 160 0.98

3 8 1.9e-06 0.00011 22.6 6.2 1 23 169 191 169 191 0.99

4 8 0.00014 0.0081 16.8 1.0 1 21 197 217 197 218 0.95

5 8 0.0067 0.4 11.5 0.3 2 21 485 504 485 505 0.93

6 8 1e-05 0.00061 20.3 1.1 1 23 805 827 805 827 0.94

7 8 0.00018 0.011 16.4 7.9 1 23 833 855 833 855 0.98

8 8 0.072 4.3 8.2 7.1 1 21 861 881 861 882 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.042	2.5	9.0	0.1	1	23	105	127	105	127	0.95
2	8	4.5e-06	0.00026	21.5	3.0	1	23	138	160	138	160	0.98
3	8	1.9e-06	0.00011	22.6	6.2	1	23	169	191	169	191	0.99
4	8	0.00014	0.0081	16.8	1.0	1	21	197	217	197	218	0.95
5	8	0.0067	0.4	11.5	0.3	2	21	485	504	485	505	0.93
6	8	1e-05	0.00061	20.3	1.1	1	23	805	827	805	827	0.94
7	8	0.00018	0.011	16.4	7.9	1	23	833	855	833	855	0.98
8	8	0.072	4.3	8.2	7.1	1	21	861	881	861	882	0.96

Sequence Information

Coding Sequence: ATGGTCGCGAGAACCGATGAGAGCATGTTCGGGTGCTATGGTGACAGCTACTCGTACCGCCTGTGGAGCCTGGCCAACGTGTGGGGCGCCTGCCGATTGCAGAGCTCGCCTATGGGAGTTGGCGGTTGGTACGAACACCTGGCGGCCGCTTGGCTCGCCGACATGAGGAGTAAGCAGGTCCCCACCTCCACCACCTCGGCCAGGCGGCTGGCTAACTTAATTCGTCCGCTGGCGAGCGGCGGCGCGGGGGAGACGAAGCCGCTGGAGGAGGAGGAGGAGCGCAGCGGTTCCCCGCTGGGGCCCGGGGGCCCCTTCGCGTGCGCGCAGTGCCGCGGGGCCTACCCCTCGCGCGACCAGCTGGAGCGCCACGAGCAGCTGCACTCGCCCAGCACACAGGTGGATACCCTCAAATATACGTGCAAGATCTGCCACAAGAGCTTCGCGAATGTGTACCGTCTGCAGCGCCACATGATTAGCCACGACGACAACGCAAAGCTACGCAAGTTCAAGTGCAACGACTGCGACAAGGCGTTCAAGTTCAAGCACCACCTGAAGGAGCACCTGCGCATCCACAGCGGGGAGAAGCCATTCGAGTGCGCCAACTGCGGGAAAAAGTTCTCGCACTCCGGATCCTACTCTAGCCACATGACCTCTAAGAAGTGCCTCGTCATGAACCTCAAGATGGGCCGCATCAAGCCCAACAACCCGGCGCTGCACCCGGACCGCAGCCCCTCGCGCAAGCGCGCCGGCGCGCTCGCCGCCGCGCAGCTCAACAACAACGTCGCGAACAACGGTGGTAACTTCTACCCCATCCTGCCCAAGTACAACGAAGCCGCGGCCTTCTTCGCTTCCATGTCCTCGCAGGAGAACGGCTTCCACCGGCCGGCGCTCCCGCAGCACCCGCTACCCCCGTTCTACCTGCCCCCCGGCATGCCTCTGAGCCCGGCCTCCGGCATCACGCCCTACAGCCTGCCCTCCTCGCTCAGTCAGCTGTTTGAGCAGTTCGCCTCCTCGCAGTACTCCCAGAGAAAGATCGAGCCCTCCAGTCCGAAGGACCTGAGCCCGCCGCCTACCAACCCCGAGGATCTGATCGAGGAGGTGACGGAGGAGGATGACAAGCGCTCCGAGGGCAGCGCCGAGCTCGTCATGGACATAGAGGACGACGACGCTGTGTCGATCAAGAAGGAGCGAGACGACCGGGAGAGCGAGATGAGATCGCCCCCACGTGACTACGATTCCGTCCCTCTCAATAATAATGGCGACCAGATCGATAACAACCACTCCGGGTTCAATACGATACTTGAATCCGTGAGCGCCTCCGTGACGAAGCACTTCTTCCGAGCGAACATGGATACGCACTCGCCGATCTCCGGGAGCGTGTGCTCAAGCCGAGAGTCGCCGCTCACGCCTCAGGTGAATATCAAAGAGGAGCCGGTGGCGGGAGACTGCCCGAGGTGTTCTAGATGTAACGCTACTTTCGATAATAAAAGTGATCTCCTGGACCACGAGAAGGTGGTTTGTAACGGTTTGTTCAGAAAACACGAAAGCTTGGCAGCTCAAGTCGCAGAAACGGTAGCTCTTAACAGGTTAGAGATGGAGATGCGTACTTCCGCTCAGAGCGGCGTCAGTGCCAGTGAAGATGAAGACTTCGCTCGAGAAGAACGCGACGAGAAGGGCTCCATACACGACAGCGATAGAAAGATCAGAGTGCGTACGGCGCTGAGCGAGGAGCAGCAGTCGATACTCAAGGAGCACTATTCGATAAACCCGAGACCGAACCGGGAGGAGTTCAAGAGGATAGCGCATCAGATTGGGCTCGACAATCGGGTGGTCCAAGTGTGGTTCCAGAACAATCGGGCAAGATTCCGAAGAATGACCCAGTCCACCTCGGTGTCCGATCAACCGCTAGACTTGTCAACGAAGAAGTCGGACCCCTCGGTGACGTCCAGTCCTCTGCCGTCCCCGCCTTGCAGCATTTCAGTAACACATTCCGATTCGGAGGAGGCGGTCAACCTGAGCCAGAAGTCGTCTCGCAGCCCGACGCCGCAGCGCCCGCACTACGCGAGTGCATACCCACATTCCAATTGTTCCTCGTCTTCGTTCACTGACTTCCGGCTGTCCCCGTCGCCGGGCGAGAGCTCGGCCACCGCCGGCCACAAGCGGCTGCTGCTGCCGCAGAAGCTGAACCCGGCCATCCCCATGGACAAGCTGCTTCACTACAACGACCTCGCAAGTGCGCGCTCGCCGCTGCTCAGCATGCACCTGGCGACCGACATCCACCGGCGCGGTGCCAGCCCCGTCTACGAGCGCGCCTCCTGGGACGACGGGCATACACCTCATGACTACGATGATGACGCAACTGTACTTAAAAAGAGCAAGCTCAAGAGTGAATTTAAGGAGGGAGAGGGACAATTTGTCTGCGACCAATGCGACAAGACCTTCGTGAAGCAGAGCTCACTCGCGAGACACAAGTATGAACACTCAGGGCAGCGTCCATACAAGTGCGTGCAGTGTCCGAAGGCGTTTAAGCACAAGCACCACCTGACGGAGCACAAGCGGCTGCACACGGGCGAGAAGCCCTTCCAGTGCTGCAAGTGCCTCAAGAAGTTCTCTCACTCCGGCTCCTACAGCCAGCACATGAACCACAGGTTCGCCATCTGCAAGCCCTACCGGGACTAG
Protein Sequence: MVARTDESMFGCYGDSYSYRLWSLANVWGACRLQSSPMGVGGWYEHLAAAWLADMRSKQVPTSTTSARRLANLIRPLASGGAGETKPLEEEEERSGSPLGPGGPFACAQCRGAYPSRDQLERHEQLHSPSTQVDTLKYTCKICHKSFANVYRLQRHMISHDDNAKLRKFKCNDCDKAFKFKHHLKEHLRIHSGEKPFECANCGKKFSHSGSYSSHMTSKKCLVMNLKMGRIKPNNPALHPDRSPSRKRAGALAAAQLNNNVANNGGNFYPILPKYNEAAAFFASMSSQENGFHRPALPQHPLPPFYLPPGMPLSPASGITPYSLPSSLSQLFEQFASSQYSQRKIEPSSPKDLSPPPTNPEDLIEEVTEEDDKRSEGSAELVMDIEDDDAVSIKKERDDRESEMRSPPRDYDSVPLNNNGDQIDNNHSGFNTILESVSASVTKHFFRANMDTHSPISGSVCSSRESPLTPQVNIKEEPVAGDCPRCSRCNATFDNKSDLLDHEKVVCNGLFRKHESLAAQVAETVALNRLEMEMRTSAQSGVSASEDEDFAREERDEKGSIHDSDRKIRVRTALSEEQQSILKEHYSINPRPNREEFKRIAHQIGLDNRVVQVWFQNNRARFRRMTQSTSVSDQPLDLSTKKSDPSVTSSPLPSPPCSISVTHSDSEEAVNLSQKSSRSPTPQRPHYASAYPHSNCSSSSFTDFRLSPSPGESSATAGHKRLLLPQKLNPAIPMDKLLHYNDLASARSPLLSMHLATDIHRRGASPVYERASWDDGHTPHDYDDDATVLKKSKLKSEFKEGEGQFVCDQCDKTFVKQSSLARHKYEHSGQRPYKCVQCPKAFKHKHHLTEHKRLHTGEKPFQCCKCLKKFSHSGSYSQHMNHRFAICKPYRD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00698162;
90% Identity: iTF_00700897;
80% Identity: iTF_00696379;