Basic Information

Gene Symbol
THAP3
Assembly
GCA_036937285.1
Location
JAUPFZ010000029.1:2817366-2844203[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.54 78 5.4 1.2 1 23 370 392 370 392 0.96
2 11 0.0074 1.1 11.2 1.0 1 23 399 422 399 422 0.93
3 11 0.96 1.4e+02 4.6 0.2 1 23 426 448 426 448 0.92
4 11 0.011 1.5 10.7 1.0 1 23 453 476 453 476 0.98
5 11 0.0044 0.64 11.9 0.9 1 23 480 503 480 503 0.96
6 11 5.3 7.6e+02 2.2 0.5 2 21 516 535 516 540 0.91
7 11 0.09 13 7.8 0.2 2 23 591 613 590 613 0.96
8 11 0.024 3.4 9.6 0.5 2 20 629 647 628 650 0.92
9 11 4.8e-05 0.0069 18.1 2.5 1 23 656 678 656 678 0.99
10 11 0.00059 0.085 14.7 2.8 1 23 685 707 685 707 0.98
11 11 0.00028 0.041 15.7 2.2 1 23 713 736 713 736 0.93

Sequence Information

Coding Sequence
atgcgctgttgtgtacaaaattgtacAAATGATACTAGAAAATCGACAAAAAGTCATGGAATTACGTTTCatatATTTCCAAAAGACGTGACCCTAAGGAGTGCATGGATTGAGGCTCTTGGTCTCACCGAATGGGAGCCAAAGGAGAGAAGCACCGTCTGTTCTGAACATTTTCAACGAGATGCCTTCTACGAAACGAGGTGTGGCTTGAGGAGGATTAAAAATGGCGCCGTACCGTTACCTCTCGTCGACTCGTCTGAAGATTTAGACGCTCCTGCCACTTTGAGAgTGTGCAGGATATGTCTCACGATGGATGCTAGGATGTACCACATGTCGGATCATAAACTGGGTCTGATGTACGAGCAAATTACTGGCGTACCGgtGAATATAGACGACAAGTTGCCACAGAAATTATGTTATGAGTGCGTGGCGAGGTTGTGTTCGGCGAATGTGTTCCGATCGAAGGCTTTGAGGGCTCAAGGGCTCTTAGTGGAGAAACTGGACTCCGATAGATTTATAACAATAAGAGATGTGAAATCGATAAGTCGAGCTCACAATAAGCTGATATCAACGCTTGGGCAAAGGTTTTATGATGTTAACGACTGTGATCTATAcattaatgaaaatgaaatcattaaaatagAGAGAGAGACGGGTAATGATAACGACAACGAAGAAATACAGTTTAATCATAACGATAATGAGGAAATACAGTTTAATGATAACGATGAGGAGgttaatgatattaaaaatgatatagaaATTAAAGATGAGACCAATAATGAAATATACTTTGAAGAGTATCCCGTGTGTGATAGCGATGATGATAGAACGCTCAACGTTTACAAGAAGACGACTCGTGTTAAGAAGAAGAAGGTGAAAGTTGAGAAGAAGGTCAGAGAAGTCAAGGAGGTGAAAGAGAAGAAGCGCGGTGAATATGACAATCCTTCGACTACGATGGACAAatacAAGACATCCGATGTGAAGAGACGAAAAACGATAGACGGTCTGGACGAATCGTTGTTCACAATAACAACTTTAACTTACGAAGAACAAATAGCGGAAATCGAGCGAAGACAGGAGGCGAACTCGTATAAAAATGCACCGTTCAAGTGTACCAAGTGCTACAGAGGGTTTCAGATCCGCGACAGATACGACGCCCACATTATTAGACATAGTGAGCAAAGCGGAGCATACGAGTGCTTCATTTGCAAGACAAGGTCGAAAACTGCTCGCGCCCTGCGGAAGCACCTGACGGGTCAACACACGGAGAAATTCAGTTGCAAGGGATGTCCGTTTGTTACTAGGAACAGgGGTGTCGCTAGGGAACATGAGAAATGGCACGCGGGAACGAAATATCAATGTCCCCACTGTCCGAGCGAGTTTGAcaAACTGACGACTTATATGGGTCACATACGCATTAAACACGTCTCGGACTTCGTCTGCAATCTGTGCGGATACACGTTCATAAGCAAGAAGGGTGTCGACGTACACAAGAAGAAGAAACATCGATTGGCCGATAAGAACGTCAGCTTAGAAGGTCCTTATTGTGAAGTGTGTGAAGTTCGTTTCGTATCGGAGGAAGCGCATTCGAGGCATATGAAGCTATCTTCACGGCACAGTAGTGATAATGATCCCAATAGAATAAGGAATGATTCACAAAGTATGAACACGGAGAGGAACGGACGGGTGATGAGAAAGATCGAACGGAGACCAGTGATACACCCGCGTTCGCCCACCGTGAGCCGCGATAACAGTGGTTCACCGATCACATGCGAACAGTGCGGCGCTACGCTGCGCGACCTGCGGCTGTACGCGCAGCACTTCCGGCGCGCGCACCCCGACAAGAACCGCACCAAGTACCCCGCCATGAAGACGCCCTGCATGTGCGAGCAGTGCGGCCGCATCTTCCAGAGCATGGCCCTGCTCAAGGACCACATGTGGGTGCACACGGGCGAGAAGCGGTTCAAGTGCGACCGCTGCGAGAAGAGCTTCACGCAGAAGACGAACCTGGTGTTCCACATGCGCGTGCACAGCGCCTCGCGCCCCACCTACGAGTGTCCGCTCTGCGGGAAGCACTTCGCCTTCTTCAACAACCGCCGCCGGCACATGTTTATCCACACGGGCCTGAAGCCGTTCAAGTGTGACACGTGCGGCAAGTGCTTCACGACGGCGGGCGAGCAGCGCGCGCACGTCGAGCACGTGCACCTCAAGAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCGTGAGTACCCGCGCACGTCGAGCACGTGCACCTCAAGAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCGTGAGTACCCGCGCACGTCGAGCACGTGCACCTCAAGAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCGTGAGTACCCGCGCACGTCGAGCACGTGCACCTCAAGAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCGTGAGTACCCGCGCACGTCGAGCACGTGCACCTCAAGAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCGTGAGTACCCGCGCACGTCGAGCACGTGCACCTCAAGAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCGTGAGTACCCGCGCACGTCGAGCACGTGCACCTCAAGAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCGTGAGTACCCGCGCACGTCGAGCACGTGCACCTCAAGAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCGTGAGTACCCGCGCACGTCGAGCACGTGCACCTCAAGAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCGTGAGTACCCGCGCACGTCGAGCACGTGCACCTCAAGAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCGTGAGTACCCGCGCACGTCGAGCACGTGCACCTCAAGAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCGTGAGTACCCGCGCACGTCGAGCACGTGCACCTCAAGAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCGTGAGTACCCGCGCACGTCGAGCACGTGCACCTCAAGAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCGTGAGTACCCGCGCACGTCGAGCACGTGCACCTCAAGAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCTCCGAGCGCGAGCGTGAGTACCCGCGCACGTCGAGCACGTGCACCTCAAGAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCGTGAGTACCCGCGCACGTCGAGCACGTGCACCTCAAGAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCGTGAGTACCCGCGCACGTCGAGCACGTGCACCTCAAGAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCGTGAGTACCCGCGCACGTCGAGCACGTGCACCTCAAGAAGCCCtggccgcgccgcgcgcgcgcgcgtccgCCCGACGACTGGCGCCCCGAGCGCCCCGAGCGCGAGCGTGA
Protein Sequence
MRCCVQNCTNDTRKSTKSHGITFHIFPKDVTLRSAWIEALGLTEWEPKERSTVCSEHFQRDAFYETRCGLRRIKNGAVPLPLVDSSEDLDAPATLRVCRICLTMDARMYHMSDHKLGLMYEQITGVPVNIDDKLPQKLCYECVARLCSANVFRSKALRAQGLLVEKLDSDRFITIRDVKSISRAHNKLISTLGQRFYDVNDCDLYINENEIIKIERETGNDNDNEEIQFNHNDNEEIQFNDNDEEVNDIKNDIEIKDETNNEIYFEEYPVCDSDDDRTLNVYKKTTRVKKKKVKVEKKVREVKEVKEKKRGEYDNPSTTMDKYKTSDVKRRKTIDGLDESLFTITTLTYEEQIAEIERRQEANSYKNAPFKCTKCYRGFQIRDRYDAHIIRHSEQSGAYECFICKTRSKTARALRKHLTGQHTEKFSCKGCPFVTRNRGVAREHEKWHAGTKYQCPHCPSEFDKLTTYMGHIRIKHVSDFVCNLCGYTFISKKGVDVHKKKKHRLADKNVSLEGPYCEVCEVRFVSEEAHSRHMKLSSRHSSDNDPNRIRNDSQSMNTERNGRVMRKIERRPVIHPRSPTVSRDNSGSPITCEQCGATLRDLRLYAQHFRRAHPDKNRTKYPAMKTPCMCEQCGRIFQSMALLKDHMWVHTGEKRFKCDRCEKSFTQKTNLVFHMRVHSASRPTYECPLCGKHFAFFNNRRRHMFIHTGLKPFKCDTCGKCFTTAGEQRAHVEHVHLKKPWPRRARARPPDDWRPERPEREREYPRTSSTCTSRSPGRAARARVRPTTGAPSAPSASKPWPRRARARPPDDWRPERPEREREYPRTSSTCTSRSPGRAARARVRPTTGAPSAPSASKPWPRRARARPPDDWRPERPEREREYPRTSSTCTSRSPGRAARARVRPTTGAPSAPSASKPWPRRARARPPDDWRPERPEREREYPRTSSTCTSRSPGRAARARVRPTTGAPSAPSASKPWPRRARARPPDDWRPERPEREREYPRTSSTCTSRSPGRAARARVRPTTGAPSAPSASKPWPRRARARPPDDWRPERPEREREYPRTSSTCTSRSPGRAARARVRPTTGAPSAPSASKPWPRRARARPPDDWRPERPEREREYPRTSSTCTSRSPGRAARARVRPTTGAPSAPSASKPWPRRARARPPDDWRPERPEREREYPRTSSTCTSRSPGRAARARVRPTTGAPSAPSASKPWPRRARARPPDDWRPERPEREREYPRTSSTCTSRSPGRAARARVRPTTGAPSAPSASKPWPRRARARPPDDWRPERPEREREYPRTSSTCTSRSPGRAARARVRPTTGAPSAPSASKPWPRRARARPPDDWRPERPEREREYPRTSSTCTSRSPGRAARARVRPTTGAPSAPSASKPWPRRARARPPDDWRPERPEREREYPRTSSTCTSRSPGRAARARVRPTTGAPSAPSASKPWPRRARARPPDDWRPERPEREREYPRTSSTCTSRSPGRAARARVRPTTGAPSAPSASKPWPRRARARPPDDWRPERSEREREYPRTSSTCTSRSPGRAARARVRPTTGAPSAPSASKPWPRRARARPPDDWRPERPEREREYPRTSSTCTSRSPGRAARARVRPTTGAPSAPSASKPWPRRARARPPDDWRPERPEREREYPRTSSTCTSRSPGRAARARVRPTTGAPSAPSASVSTRARRARAPQEALAAPRARASARRLAPRAPRARA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00695674;
90% Identity
iTF_00695674;
80% Identity
iTF_00695674;