Basic Information

Gene Symbol
Zfy1
Assembly
GCA_036937285.1
Location
JAUPFZ010000029.1:4864208-4889092[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 2.1 3e+02 3.5 3.6 1 23 277 300 277 300 0.96
2 11 0.021 2.9 9.8 0.3 1 23 306 328 306 328 0.97
3 11 0.099 14 7.7 0.8 1 23 332 355 332 355 0.95
4 11 1 1.4e+02 4.5 2.7 1 14 362 375 362 384 0.76
5 11 8.5e-05 0.012 17.3 0.8 3 23 390 411 389 411 0.93
6 11 3.3e-05 0.0048 18.6 1.1 1 23 417 439 417 439 0.97
7 11 0.11 15 7.6 1.8 3 21 454 472 453 477 0.92
8 11 0.00013 0.018 16.8 1.7 1 23 485 508 485 508 0.94
9 11 0.0023 0.33 12.8 0.3 1 23 513 536 513 536 0.97
10 11 6.4e-07 9.2e-05 24.0 2.9 3 23 545 565 544 565 0.98
11 11 1.7e-06 0.00024 22.7 3.4 1 23 571 594 571 594 0.96

Sequence Information

Coding Sequence
ATGGAGAATAAAAACGATATATTGAACAATTTGCTGTGTATGGCATGTCTCTGTGTCGGCAGATCGATACATGAAGTGAAGGACGAAAGGTTTAAAAAATACTACATGGACATATTGAACGAAATACccctGAACGATATACAGAAGGTCGTACCAATAATATGTTGGGAATGTGACGCTGTTCTACGGAAGGTTTTATCGTTCAGAGAGCAAGTGAAGGATTCTTATAGGATATTGCAAACATATACTGAGAATCTGAATGAATGTCTCCTGAGTGACGTCTCGAGAACTCCGAGACTGAAGGTTCACATCAACGAGTCGGTTGTCATAAATCCATGTCCAAGTGTTAAAACGGAAATTAAACTGGAGAGATATGgagacgatcgtaaatttgaaacacaaAATGTCGAAAATAGTAACGACAGAGACGATTCAGATATTGAACCAGAAACAATACAGACTGTACTCTGTGATGTTAAAAGAGATAGAAAGAAGAAAAAGAATTCACAAAACGAAACGAAACCATCGGATTTGAGTTTAAAAACTGAAAACGGAACGTCGGaagatgaatttaaaattgaatCTGATAGAGagtatGATATGTCGGATGACCCAGTGTCCGATGTGGATGATATAAATGATGTGGATACGGAAAtacgaaatttatttaatgaagtTAACAAAAAAGTGAAATCTAAATACAAAACATCTAATATTAAGGACAAAAAAggcaaattaaaacaaatagaaACGATCGAACTCTCCTATGACGAGATGCAAGCGGAGAGAACTCTCCTCGCAGCAAGGGAGAGCTTTAAGAAAGCTCAGTACAAGTGTGAAACGTGCCTTATATTATTCAACTGCGCTTCTTCACTGAAAGCTCATCATGCTAAGAAACATGCGATACCGGGAAATTTTATATGTTCAATATGTAAAACAATTATATCATCTGTGGAGGCGTTTACCGCGCATTACAAAAGACATATGAGAAGGTACGAGTGCGCGGTGTGTAAAAAGCGATTGACAGACGTAAAAGCGATGTACCAACATCTCTACAAACGACACGAAATATCCCTCAAGAAATACAAGTGCAATGTATGCGGCAAAATATCTAATTCAATAGACAGCCACAGAAATCACTGTGACACGCATAAGGCTCGAGTCGCATGCTCCCAGTGTGACAAGACCTTTAGTCATAGAGCGGGACTGATGAACCATAGACTTGCAGTTCATGAATGTCAGAACGAGTTCCCTTGCAATCTCTGCGACAAGGTCTTCAGATGGAAGACCAGTCTGAAGCGACATCTAGAGAAGCATGACACCGGTaatAAAAGTAGTACTAGTTCGAACAGGGCGTTCTGCGCATCGTGCGGCATCGGTTTTTCGTCTGTCTGTTCGTTTCAGCGCCATCTCAGAAACAGTCTTAAACACGTCACACATGATCAACTCAAgtTCATCTGCGACCATTGCAACCAGAGGTTCGCGGACAAGACGAAGTTAAGAGACCACATCGAAGAAAAACACCTGCACAGAACCTTCCAGTGTCCCATATGCTGCaagCCGTCAAAAAACCGCGTTGGCTTAGAGCAACACATCCGCGCGGTACATAAAGGAAGACCGAACAACCGGATGTGCCATCACTGCGGGAAGGGATTTCCGACTAAAGTTCAGCTAGAGTCCCACATACGGACACACACCGGCGAACGGCCCTTCATGTGCGAATACTGTCCCACGACCTTCTCCCAGCAATCCAACTTGTACAAGCATCACCGGCAGGTGCACCTAAACATCAAATCCAAGAAATATATCTGTAAGAAGAGGAAAGTCGACGGAAATCAATGTAGCGAACAACAAGAATTCTCACTGCCTATCATACAGTATATGCCCGATAATGGATTCAGCTTGTAa
Protein Sequence
MENKNDILNNLLCMACLCVGRSIHEVKDERFKKYYMDILNEIPLNDIQKVVPIICWECDAVLRKVLSFREQVKDSYRILQTYTENLNECLLSDVSRTPRLKVHINESVVINPCPSVKTEIKLERYGDDRKFETQNVENSNDRDDSDIEPETIQTVLCDVKRDRKKKKNSQNETKPSDLSLKTENGTSEDEFKIESDREYDMSDDPVSDVDDINDVDTEIRNLFNEVNKKVKSKYKTSNIKDKKGKLKQIETIELSYDEMQAERTLLAARESFKKAQYKCETCLILFNCASSLKAHHAKKHAIPGNFICSICKTIISSVEAFTAHYKRHMRRYECAVCKKRLTDVKAMYQHLYKRHEISLKKYKCNVCGKISNSIDSHRNHCDTHKARVACSQCDKTFSHRAGLMNHRLAVHECQNEFPCNLCDKVFRWKTSLKRHLEKHDTGNKSSTSSNRAFCASCGIGFSSVCSFQRHLRNSLKHVTHDQLKFICDHCNQRFADKTKLRDHIEEKHLHRTFQCPICCKPSKNRVGLEQHIRAVHKGRPNNRMCHHCGKGFPTKVQLESHIRTHTGERPFMCEYCPTTFSQQSNLYKHHRQVHLNIKSKKYICKKRKVDGNQCSEQQEFSLPIIQYMPDNGFSL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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