Esab013863.1
Basic Information
- Insect
- Eumerus sabulonum
- Gene Symbol
- su(Hw)
- Assembly
- GCA_951905685.1
- Location
- OX645060.1:195497391-195508438[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 16 0.0049 0.87 11.3 1.7 1 21 61 81 61 82 0.93 2 16 2.1e-06 0.00038 21.9 0.3 3 23 133 154 131 154 0.92 3 16 0.1 18 7.2 0.0 1 23 160 182 160 182 0.96 4 16 2.9e-06 0.00052 21.4 2.0 1 20 189 208 189 210 0.93 5 16 1.1e-05 0.002 19.6 2.6 1 23 221 243 221 243 0.98 6 16 0.0059 1 11.0 5.3 1 23 254 276 254 276 0.98 7 16 5.8e-05 0.01 17.4 1.0 1 23 282 304 282 304 0.97 8 16 0.00059 0.11 14.2 4.4 1 23 310 332 310 332 0.98 9 16 1.2e-06 0.00021 22.7 0.7 1 23 338 360 338 360 0.97 10 16 6.4e-05 0.011 17.2 0.8 1 23 364 386 364 386 0.98 11 16 0.002 0.35 12.5 5.2 1 23 410 434 410 434 0.92 12 16 0.071 13 7.6 1.4 2 23 441 463 440 463 0.95 13 16 2.2e-05 0.0038 18.7 0.2 1 23 465 488 465 488 0.94 14 16 0.00071 0.13 13.9 1.3 1 20 769 788 769 790 0.95 15 16 3.8e-05 0.0067 17.9 0.4 3 23 841 862 839 862 0.90 16 16 0.018 3.2 9.5 0.0 1 23 868 890 868 890 0.97
Sequence Information
- Coding Sequence
- ATGGAATTCAAAGATAGCGCGGAGGAGAACAACATTGATTTCATTCTAACCCAAACTCGTGGGCAAGGTAATATTCGAGGACCTACGGAATGCCTGGAAGAGATCGAATTTACCGAGAAAGTATCGCCCGATGATAAAAACGATGGGAGTGAAAATGTAAAAGTACAAACTGTTATTGAGCATATATGTGGAAAATGTTACCAATTCTttcgctccattaagtcCCTTAAACGTCACATGGAATATTGCAATTTCAACAGCGAAATGATACTACGACGTGAAGAAATGCTAAAGAACATCGATAAGATAGAGAAAGAAGCAATAATCATGGAGAAGAAAGATCTATGCTTTTGCTGCGGAGATAGTTACGATACTTGCCACCTCGGTCATATAAACTGTCCTGATTGTCCGAAAACATTCAAGACACAACTGAGTCTTGAGCGTCACATGTTTCTTATTCACTCGGAAAAGGATGACTTTCCTTGCACGATTTGCAATGGTAAAATTCGAACTGCAGCCTTATTGGAATTGCATACTGAACAGCACAAGACCCGTGGTAAACCGTTTGCCTGTAAGATTTGTGGTAAAGATTTTACGCGAAGATATCACTTGAAACGTCATGAAAACTTCTCACCGTGCGGCCAAAATCAAACGGAAATGCACAAATGTAAAGCTTGTGATAGAGAATTTTATCGCTTGGATAATTTACGAGCTCATCTGAAGACGCATCTTGATAAGCACTCGGCTAAGAAACATGAATACATGTGTCCGTGCTGTAAGAATTGCTTTTACAGTTTGTCAACTTTGAATATTCATATAAGAACTCATACGGGCGAAAGGCCGTTTGATTGTGACTTGTGCGAAAAGAATTTCCCATCGTTGGTTTCGTTGAAAAAGCATAGGAGATATCACACGGGTGAGAAGCCATACTGCTGCTCTGTGTGCAACCAACACTTTGCAGTCAAGGAGGTTCTTAACAGGCATATGAAACGACACACAGATGATAAGCCACACGTTTGCGGTGAATGCGGAAAACGTTTCATTCAGGCCACCCAACTAAAGAAACATGTTAACGTCCATCAACGACCGTACGAATGTACCATATGCACAGAAAAATTTAAGACAGAGAGACAGATTGAAAAACACCTTAGAGCGCACAACAAATTGCTCAGAAAAGCAAATTCGGCGCAGAACATaataaccagaaaaaaaaattcgtcGGGAAAATATTGTTGTCATGAATGTGACATACAATTCTTCCGTCAGTATTCCCTCTTGAAGCACGAGAAGACGCAGGAACACAAGGAAAAGGCTACGAAAACCTGTAAGTACTGTAACGAACAATTCGTGGGTACAAAGTCGTTAAACTTTCACATGCTCAAGGAGCACGAATTCAAATGTAACCAATGCGACGTTGTATTCATATATAGCGACCTTCTTCAGAAACACATTGAAGCCAACCATAAGACTTCCCTTGCCGTTGACAAAGTAGTTGTCGAGGAGGATATCGGGCAAGATATCGAACCGATCGTGGCAAAAGTTGAAAATCAAACCCCCCCTGCAAGAAAAGTGCTTACAGAACACGGCTGTTTTGTAATCGAAGAATTTATTATTGAATCGCTTCCAGCCGATAAAATGCAAACAAGCACTGAAAGCAAATATACCATAATCCCCAAGACGAGTGAAGCATCGTCACAAGACTCGAACACGACGTACGAAGAGCGCTCGAAAAATCTTAAGGCCCAATTTAAAAAATTACTAGAAGAGAGCGTGGACGATCGCGACGACAAAATGGAAGTCGAGATTAAAGACGATATCTTAATCACTAATAATATTGGTAAACTATTGGATATGCTTGTGGATGTAAAGACTCTAAGTAAATTTGGATGGCCTGAAAGTAGCGTTGAAGAGGTTTTGTGTAAAGTGATAGAGAATTGCGGGCATAATCTCAATAGGAATGAATTCTCTGATGAGTACGGTGCACGGATGAGAGAATACGTGAAGCTCTTCTTCACCGTAGTGATTCAGAATGATTCAATTGAGGAGCTTTTGAATAACTACACGATAGATGAGGTTATCGAGCTAGTTCTTTCCAACGAGGATGCCGTGTCCACAACATCGTGTATAAAAGCTTTAAATTCAAATACAAATGCACCAGAGACGTCATCCCCAACAACATCAATTGACGATGAGAATACCATCTACAAGCCACCAGATCAGTATATCGAAGAAATCGAATTCGTTGAGTCGGGAGAGGGAAATAAAAACGACGAAGGTGATTACAAGCTCAAGGAAGTGGTCGAGCATGTTTGTGGAAAGTGTTACAAATCTTTCAGCAGAGTCAAGGTCTTGAAACGCCACATGGAATTCTGCCTCTTCAGTAATGCCGTAGTGTCCCGAAGGCAGGAGATGCaaaagaatattataaaaattgaAAATGAGGCTACAAGCATGGAAAAGGACAATATATGCTTCTGTTGTGGCGACAGCTACGATGTCTGTCACTCGGGTCACATAAACTGTTCAGATTGCCCGAAAACTTTTAAGACACAACTCAGCCTGGAACGTCACGTGTTTCTCATTCACTCCGAGAATAATGAGTTTCCCTGTACCATATGCAATGGTCGTATTCGTACTGCTGCATTGCTTAAACTTCACATCGAGCAGCATACAACTCGCGGTTGA
- Protein Sequence
- MEFKDSAEENNIDFILTQTRGQGNIRGPTECLEEIEFTEKVSPDDKNDGSENVKVQTVIEHICGKCYQFFRSIKSLKRHMEYCNFNSEMILRREEMLKNIDKIEKEAIIMEKKDLCFCCGDSYDTCHLGHINCPDCPKTFKTQLSLERHMFLIHSEKDDFPCTICNGKIRTAALLELHTEQHKTRGKPFACKICGKDFTRRYHLKRHENFSPCGQNQTEMHKCKACDREFYRLDNLRAHLKTHLDKHSAKKHEYMCPCCKNCFYSLSTLNIHIRTHTGERPFDCDLCEKNFPSLVSLKKHRRYHTGEKPYCCSVCNQHFAVKEVLNRHMKRHTDDKPHVCGECGKRFIQATQLKKHVNVHQRPYECTICTEKFKTERQIEKHLRAHNKLLRKANSAQNIITRKKNSSGKYCCHECDIQFFRQYSLLKHEKTQEHKEKATKTCKYCNEQFVGTKSLNFHMLKEHEFKCNQCDVVFIYSDLLQKHIEANHKTSLAVDKVVVEEDIGQDIEPIVAKVENQTPPARKVLTEHGCFVIEEFIIESLPADKMQTSTESKYTIIPKTSEASSQDSNTTYEERSKNLKAQFKKLLEESVDDRDDKMEVEIKDDILITNNIGKLLDMLVDVKTLSKFGWPESSVEEVLCKVIENCGHNLNRNEFSDEYGARMREYVKLFFTVVIQNDSIEELLNNYTIDEVIELVLSNEDAVSTTSCIKALNSNTNAPETSSPTTSIDDENTIYKPPDQYIEEIEFVESGEGNKNDEGDYKLKEVVEHVCGKCYKSFSRVKVLKRHMEFCLFSNAVVSRRQEMQKNIIKIENEATSMEKDNICFCCGDSYDVCHSGHINCSDCPKTFKTQLSLERHVFLIHSENNEFPCTICNGRIRTAALLKLHIEQHTTRG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -