Basic Information

Insect: Eumacrocentrus americanus
Gene Symbol: ZFHX3
Assembly: GCA_018902335.1
Location: JABSMT010005932.1:1-8832[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.21 19 6.0 0.1 2 23 329 351 328 351 0.91

2 16 0.00016 0.015 15.8 1.8 2 23 572 594 571 594 0.95

3 16 4e-05 0.0037 17.7 0.7 1 23 626 650 626 650 0.92

4 16 0.0059 0.54 10.9 0.4 1 22 707 728 707 731 0.91

5 16 5.6 5.1e+02 1.5 0.8 2 20 958 976 957 981 0.88

6 16 2.8 2.6e+02 2.4 1.5 1 23 1005 1029 1005 1029 0.91

7 16 0.0017 0.16 12.6 0.2 3 23 1123 1144 1123 1144 0.98

8 16 0.06 5.5 7.7 0.1 3 23 1165 1186 1164 1186 0.95

9 16 0.00048 0.044 14.3 3.4 2 23 1248 1270 1247 1270 0.95

10 16 0.0021 0.2 12.3 1.1 1 23 1287 1309 1287 1309 0.96

11 16 0.00012 0.011 16.2 0.2 2 23 1316 1338 1315 1338 0.95

12 16 0.0017 0.15 12.6 3.3 1 23 1426 1450 1426 1450 0.91

13 16 0.0046 0.43 11.2 0.6 1 22 1470 1491 1470 1494 0.89

14 16 0.00063 0.058 13.9 0.2 1 23 1535 1559 1535 1559 0.93

15 16 0.078 7.2 7.3 0.1 2 21 1606 1625 1605 1626 0.94

16 16 0.14 13 6.6 2.0 2 19 1771 1788 1770 1793 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.21	19	6.0	0.1	2	23	329	351	328	351	0.91
2	16	0.00016	0.015	15.8	1.8	2	23	572	594	571	594	0.95
3	16	4e-05	0.0037	17.7	0.7	1	23	626	650	626	650	0.92
4	16	0.0059	0.54	10.9	0.4	1	22	707	728	707	731	0.91
5	16	5.6	5.1e+02	1.5	0.8	2	20	958	976	957	981	0.88
6	16	2.8	2.6e+02	2.4	1.5	1	23	1005	1029	1005	1029	0.91
7	16	0.0017	0.16	12.6	0.2	3	23	1123	1144	1123	1144	0.98
8	16	0.06	5.5	7.7	0.1	3	23	1165	1186	1164	1186	0.95
9	16	0.00048	0.044	14.3	3.4	2	23	1248	1270	1247	1270	0.95
10	16	0.0021	0.2	12.3	1.1	1	23	1287	1309	1287	1309	0.96
11	16	0.00012	0.011	16.2	0.2	2	23	1316	1338	1315	1338	0.95
12	16	0.0017	0.15	12.6	3.3	1	23	1426	1450	1426	1450	0.91
13	16	0.0046	0.43	11.2	0.6	1	22	1470	1491	1470	1494	0.89
14	16	0.00063	0.058	13.9	0.2	1	23	1535	1559	1535	1559	0.93
15	16	0.078	7.2	7.3	0.1	2	21	1606	1625	1605	1626	0.94
16	16	0.14	13	6.6	2.0	2	19	1771	1788	1770	1793	0.91

Sequence Information

Coding Sequence: ACGACCTGGGGTTGCGACGGGGTAGCTAGTAAATCTTCTACCGTGGTCGAGGACGAGAATAAAACGGGGCGAAGGAAGGCGGAAACTCGATTTACCCGGGTGTCGTGTGCGGTGGGAGGAGGACACAGAGGACGTACATACCATCTTCAACACCACACGATTCCACCCTCGCACCTGCAGCAGCACTCGTCGTCACCGACGAGCGCAATCGGGCAGCATCAGCTCTATCAGCAGCTGGTGGCGGCCCATACCCAGCAGCAACACCAGAGCCAGCAGCACGGCGTTGGATATCTTCAAAATTCCGCGTACGCGCAGCAGAAACCGGAGATGAGCCCGGAGGAGGAGGGCGGCCGAAGCGGCGGGTCCCCTCCGACGGCGGGAGCTGCTCTCCATCAGCCCCATCATCCCCGCACGGCCAGTCCGCCATCGGGCACGGAACCCTGCACGCGGGACGCCATACCGACGCCCACGCCGACCGCGGACACCACCTCCACGACCAACAGCACGACGGCTGCCGCGACAACCATGACCATGCAGTCACCGAGTCAGCAGCAGCAACAGCAGCAGGGTCCAAGTCCCAGTCCAAGTCCGACGGGTGGTGATGTCGAAAAATTCGACGGCAAGATCGTCTACAATCCGGACGGATCGGCGTACATCATCGAGGGCGAGAGCGAACTCAGCGAGGACGACTCCCTTCCCGATGGTTGTATCGTCGATGGACGTGGCGTCTCCGTGCCGCACTCTCTGGTCTTTCCACAAATAGCCAGCGCCTTCTATGTCTCAAGGCTCTATGCCCATCAGGCGTATCAGCAACATCAGCAGCAACAGCAGCAGCAGAGATCGACGCAGTCGCATAATCCTGATTTGCCAGTGATGCATAGCTATCGGGTGATCAGTTACAGAAGTGCCGAGGGCACGAAACAACCGTCGCCCACGCCTGTCTCACCGCCGTCATCCACGTCAGTGCCCGTCAAGCCGATCCTCATGTGCTTCATCTGCAAGCTGAGCTTTGGCTATGCCAAGAGCTTCGTGGCACATGCCCAGGGCGAGCATCAGTTGACGATGACGGAGGACGAGAGGCAGGTGCTGTCGCACTCGACGGCGTCTGCAATTATTCAGGCTGTGGGCCGGGGTAAACAGCCCCTGGTCAGTTTCTTGGAGCCAGTCACGAGCTCGTCGTGTCCGCAGAACTCGCCGGTGCAGTCGCAGACACAGCAGCAGCAGCAGCGCGGATCCGACTCGAATGAGCACGAGACGCCTACGAGGACGAGTACGCCAGCGAGTACACCGGGGATACCGAGCAGTCCGCAGGCGCAACAACAGCAGAGGCCGTCGCCGAGTACACCTACGACACCAACGTCGCACTCGAGTAATTCCCTCAGCTTCAATCATCAAGCTCAACAACATCAGTGGACGGGTGGTCAAGTAAGCGCGGCAGCGTGGGCCAAGGCTCCCGATGCGATGCTCTACACCTCGCCACCGCCACCTCCGCCTTCGTCGACCAAGGGCTCGCCCTCGTCGTACGTGGCACTTACTCAACAACCACCGAATTTTCTCACTGGCACGACAATCGGCGTGTGCCCGGAGCACATGCAGGGCCGACCCAGTGGCGTCGAGTGTCCCAAATGCGAGCTTATCCTCGCGAGCAGTCGACTTGCTGGTCCTGGAGGCCCACTCGCCGGCATTCACAGCCGGAACTCGTGCAAAACCCTCAAGTGTCCCAAGTGCAATTGGCACTACAAATACCAAGAGACTCTCGAGATTCATATGAAAGAAAAGCATCCCGAGAGCGAGACGTCGTGCATCTACTGTATAGCTGGACAACCGCACCCAAGGTTAGCGCGGGGCGAGACGTACACTTGCGGTTACAAGCCGTACAGGTGCGAGGTCTGCAACTATTCAACGACGACCAAGGGCAATCTCAGTATACACATGCAAAGCGACAAGCATCTGAACAATATGCAAGAGCTTCAGCAGGGCGGTGGTGCAGCCACAGCCACGAGTAATCCATCGTCGTCGCAGGACGCGCCCATGCCCACGCGGAGTCCTCATCATCAGCAGAATCACAGTCCTCACCTGAGTGGCCCAACGGTCACGCAGGGAAAACCCAAGCCCACCTTTCGCTGCGACGTTTGCAATTATGAAACGAATGTCGCGAGAAACCTCAGGATACACATGACGAGTGAGAAGCACACGCACAATATGCTGGTCCTCCAGCAGAATGTCAAGCACATGCAGACACTCTCGGCACTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACTGGACAAGCCCCAACACGCCGAGGCAGCGCTCGCTGACATGGCCTATAACCAGGCCCTCCTTATCCAGATGATGACTGGTGGTCAGTTGCCTCCGCAGCTTCCACCAGAGCTCATGGGTGGCATGGCGAGTATGACTGCCATGGGAAATCTCAGTGGCGATGTTGGCCTGTCGCCCGACAGCATGGAACCCCCACCAGAACCAGCGGATCCCGATCCCTCTCACCTCTATCACTGCTGCGTCTGCAACAACTTCAGCTCAGACTCTCTCGAAGCCCTTGGACATCATCTAGCCACGGATCGGACGAGGACGCGTGAGGGCGAAATTCTGGCACTCGTTGCCGGCAATTTCGTCTGCAAATTGTGTTCCTACAAGACCAACCTCAAAGCCAACTTCCAGCTACACTGCAAGACAGACAAGCATCTTCAGCGGTTGCAGCATGTCAACCATGTGAAGGAGGGCGGCCCGAGAAACGAGTGGAAGCTCAAGTATCTCGCGTCTCCAACGAGCGCCGCACAATTGCGTTGTCATGCCTGTGACTACTACACGAACAGTGCCCACAAGCTTGCCCTACATGCGGCCTCACCTCGGCACGAAGCCGCGGCTTTGCTTCTTCGTCATCTGCTCGAAGCCAGTGCCAATACCCAGTCGGTGGGTAAACTCTACCACTGTGCTCTATGCGGCTTCAGTGCGAGACACAGACTGCCGCTTCTTCAACACGTCAGATCACTCAGGCATCTGCAGATGGAGCAGCTTCATCAGCTGCACAGGAGAAGTGGCATTCAAGGCAACGATCCGCCGCACACCGACATTGGCGATGTTTTTCAAGTTGTCGCCGATCCTGACGCGCCATCAACTCAGCAAGCTAGTCCCACGACACCGACGACGCCCAATGCCGCGAGCTCCAACAACGAGCGGCGCGAGGAGGGCAGTGACTGTGGCAGCGAAGTGAAGCAAGAGCCTGACAATGACCAGGAGCAGGACCAAGAGCCTGAAAACGAGACTGAAGAAATTGGGTGTCCCTATTGCACCTACCAAGTAACGTCTAAAGAGGAACTGAAGCAACATCTCCAAGTGGCTCACACTCAGGACTCTGACGAGAAGATGGAGATGGTGAAGGAGGAGCCAACGCCAGAATTGCTGTGTCCCTTGTGCCAAGATAGCTTCAAGGAGCGAGCAGCTCTGGAGAAACACGTGATGCAAATTCACTCAGTGAATGCTGATGGTCTTCAGAGGCTTCTACTTCTCGTAGACCAAAGTCACTGGCTGAATAATAATCCCAGGAGCACCTCGACACCAGCAGCGACTCCAACGTCACCAAGCACCATCACCAAACAGAACCAAGACGAGGAAAATGAGAGAGCGAGTGTAGACGAGGTCGAGGAGATTACCAGGTGTACTATCTGCGGTCGAGTCTGTCGATCTCTCGAAGAACTTCAACAGCATCACAGAGAATCTCATCCAGCATCAACCCCCACGATGGCTGTCAGCGAGAAGCACGTGTATAAGTTCCGATGTGTTCAGTGCAGTTTGGCTTTCAAGACTCCAGAAAAATTGCAACAACACTCTCAGTACCATGCAATCAGAGACGCCACCAAGTGTGCGCTCTGTGGCCGTTCCTTTCGTTCAGTCCAGGCGCTTCAACGACACCTGGAGTCTGCTCATGCCGATCTGCACGAAGACGAGCTGGCGCAGTACAAGCAGAGTCTACTACACGCGCACCCACTGCTTCAAGCAATCACTGAAGAGGCTCTCAGGCGACAAGGGAATCTCAGTGGCGAACAGAACGCCGAGGAGGACGCTCGAGATGAGGAGGAGAGTGATGCCAGTGACTCGTCACCGCTTCACAAAGAACAAAGACTCCTGGAGGACTATCTTAATAGTCAACCAGTGGCTGAAGACTCGTACTACGATCCCGGACGTAAATTCAAGTGCCATCGATGCAAAGTCGCGTTCACGCGCCAGAGCTACCTCACTGGACACAATAAGACTCTGCTCCATCGCAAGGGCGAAAAGATGACTTATCCGATGGAGAAATACCTCGACCCAAATAGACCGTACAAGTGCGATGTGTGTAAAGAGAGTTTTACGCAAAAGAACATTCTCCTCGTGCACTACAACAGTGTCAGTCACCTGCACAAGCTGAAGAGGGCGATGCAGGAGCAAGGCAATAATAATACTCTGATCTCTGTCGTTCCACCAGCGAGTCCCACCGAGTCGCCTGATTCCCAACAGGATCAGGATAAAAAACCGTACAAGTGCAACATCTGCAAGGTTGCCTACTCCCAAGGAAGTACTCTGGACATTCATATGAGAAGTGTTCTTCATCAGACGCGAGCCAGCAAATTGCCAGATCTTGCAGCGAGTGGTCAGCTGGATTTAGCGAGACCCCTCATTGAACAGCCACCACCAACTAGTCCAAACAGTCCGCCCTGTAACACCAATAGCAATAACAGCAATATGCTCTCGTGTCCTCGTTGTAGTGCTCTCTTTGTCAATCAAGAGCAATTGTCAACTCATCAACAGTTATACTGTATTTTCAGTAATCCATTGGCATTATTCCAGCAACTCGCAGCAACTCAACAAATTGCGTCCTCGACGTCAGACAAGACTCCACCACCAATGTCGACGACTCCAGGTCCTCAGCAGCACGCTCAACAGACCCAACAATCCAATCAAGTAGCCCAAGATATTTTATCTCAACCGCGACACAAGACTTCTCAAATGTACAAACATCTGCTCGAAAGTTTTGGTTTCGATCTCGTGATGCAATTCAACGAAAATCATCAGCGACGTCAGAGAAAAGAGGAGGAGGCTGCTGCAGCTTTGCAAGCTCAACAAGAACAGCAGAAACAGGAGCAACAGAAGCAGGCATTAGCTGCTCAGCAGGCTCAAGAGCGAGAAGATCAAGAAGTTGAAGAACATGGCGAGGAGGAAGCTATTCCTGAGTTAACGAGAAGCACGTGTCAACACTGTAACAAAGAGTTTAGCAGTGTTTGGGTGCTAAAGGCTCACTGCGAAGAGGTACATCGTGACCTGGTGCCACGAGAGTTCCTGGAAAAATATGCCCAGCAGTTTAAGTGTGAGTACGAGAAGAAGAGCGTTGTTGTGACTGCAGCCACGTCATCGTCCACAACGACTGCCCCTCGAAGCTCGACCCCGGCGTCCAATCAGCCACAGGATTTGAGCCCTGATAAGGAACGACGCGATAAGGAGAAGGAAGAGTCGCCAGAAAGTAAAGAACGCGCCAGTCGCACTCCAGAAGCCACCTCGACCACTCCTGTGACAACGCCAGCATTGAGTAATACTCCAGTGTCGAGTACAGACTCTACGACGCCTACTGCACCCACTGGCAATACTCAACATCATATGCAGCCACAGCAGCAACAACAGCAACACGCTCAAATGACATTGGCTCAACAAATGTCAGAGATGCAGGCTGCATTAAACGCCATGGCTGCCTCACAACTGCAGCAACAACTTCAACAGTATCCTGGTCTGATGATGGGCATGATGGGACTGCCATTGGGTCTCAATGTGCCTGCTCTTGCCGCTATGAATCTTCAGCCGCCTCTTGTGCCCATGATGCTACCACCACCACCGTATGATGGTGCTGCTGCTGCTGGTTATCCACAAATCCCAGCGCCGGCAGATCTTCTTGCCAAGCAACATCTTGCGATGCAACAGCAGCAAGCAGCTGCGGTGAGTTACTAA
Protein Sequence: TTWGCDGVASKSSTVVEDENKTGRRKAETRFTRVSCAVGGGHRGRTYHLQHHTIPPSHLQQHSSSPTSAIGQHQLYQQLVAAHTQQQHQSQQHGVGYLQNSAYAQQKPEMSPEEEGGRSGGSPPTAGAALHQPHHPRTASPPSGTEPCTRDAIPTPTPTADTTSTTNSTTAAATTMTMQSPSQQQQQQQGPSPSPSPTGGDVEKFDGKIVYNPDGSAYIIEGESELSEDDSLPDGCIVDGRGVSVPHSLVFPQIASAFYVSRLYAHQAYQQHQQQQQQQRSTQSHNPDLPVMHSYRVISYRSAEGTKQPSPTPVSPPSSTSVPVKPILMCFICKLSFGYAKSFVAHAQGEHQLTMTEDERQVLSHSTASAIIQAVGRGKQPLVSFLEPVTSSSCPQNSPVQSQTQQQQQRGSDSNEHETPTRTSTPASTPGIPSSPQAQQQQRPSPSTPTTPTSHSSNSLSFNHQAQQHQWTGGQVSAAAWAKAPDAMLYTSPPPPPPSSTKGSPSSYVALTQQPPNFLTGTTIGVCPEHMQGRPSGVECPKCELILASSRLAGPGGPLAGIHSRNSCKTLKCPKCNWHYKYQETLEIHMKEKHPESETSCIYCIAGQPHPRLARGETYTCGYKPYRCEVCNYSTTTKGNLSIHMQSDKHLNNMQELQQGGGAATATSNPSSSQDAPMPTRSPHHQQNHSPHLSGPTVTQGKPKPTFRCDVCNYETNVARNLRIHMTSEKHTHNMLVLQQNVKHMQTLSALXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLDKPQHAEAALADMAYNQALLIQMMTGGQLPPQLPPELMGGMASMTAMGNLSGDVGLSPDSMEPPPEPADPDPSHLYHCCVCNNFSSDSLEALGHHLATDRTRTREGEILALVAGNFVCKLCSYKTNLKANFQLHCKTDKHLQRLQHVNHVKEGGPRNEWKLKYLASPTSAAQLRCHACDYYTNSAHKLALHAASPRHEAAALLLRHLLEASANTQSVGKLYHCALCGFSARHRLPLLQHVRSLRHLQMEQLHQLHRRSGIQGNDPPHTDIGDVFQVVADPDAPSTQQASPTTPTTPNAASSNNERREEGSDCGSEVKQEPDNDQEQDQEPENETEEIGCPYCTYQVTSKEELKQHLQVAHTQDSDEKMEMVKEEPTPELLCPLCQDSFKERAALEKHVMQIHSVNADGLQRLLLLVDQSHWLNNNPRSTSTPAATPTSPSTITKQNQDEENERASVDEVEEITRCTICGRVCRSLEELQQHHRESHPASTPTMAVSEKHVYKFRCVQCSLAFKTPEKLQQHSQYHAIRDATKCALCGRSFRSVQALQRHLESAHADLHEDELAQYKQSLLHAHPLLQAITEEALRRQGNLSGEQNAEEDARDEEESDASDSSPLHKEQRLLEDYLNSQPVAEDSYYDPGRKFKCHRCKVAFTRQSYLTGHNKTLLHRKGEKMTYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQGNNNTLISVVPPASPTESPDSQQDQDKKPYKCNICKVAYSQGSTLDIHMRSVLHQTRASKLPDLAASGQLDLARPLIEQPPPTSPNSPPCNTNSNNSNMLSCPRCSALFVNQEQLSTHQQLYCIFSNPLALFQQLAATQQIASSTSDKTPPPMSTTPGPQQHAQQTQQSNQVAQDILSQPRHKTSQMYKHLLESFGFDLVMQFNENHQRRQRKEEEAAAALQAQQEQQKQEQQKQALAAQQAQEREDQEVEEHGEEEAIPELTRSTCQHCNKEFSSVWVLKAHCEEVHRDLVPREFLEKYAQQFKCEYEKKSVVVTAATSSSTTTAPRSSTPASNQPQDLSPDKERRDKEKEESPESKERASRTPEATSTTPVTTPALSNTPVSSTDSTTPTAPTGNTQHHMQPQQQQQQHAQMTLAQQMSEMQAALNAMAASQLQQQLQQYPGLMMGMMGLPLGLNVPALAAMNLQPPLVPMMLPPPPYDGAAAAGYPQIPAPADLLAKQHLAMQQQQAAAVSY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -