Eame008190.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Eumacrocentrus americanus
Gene Symbol
-
Assembly
GCA_018902335.1
Location
JABSMT010054348.1:349-3095[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 1.4e-05 0.0013 19.1 0.7 2 23 314 335 313 335 0.97
2 11 0.00016 0.015 15.8 1.2 1 23 343 366 343 366 0.96
3 11 0.0019 0.18 12.4 1.5 1 23 409 431 409 431 0.97
4 11 1.1e-06 0.0001 22.6 1.8 2 23 462 483 461 483 0.97
5 11 6.1e-05 0.0056 17.1 4.1 1 23 488 511 488 511 0.97
6 11 1.7e-06 0.00016 22.0 1.1 1 23 623 645 623 645 0.98
7 11 8e-07 7.3e-05 23.1 0.9 1 23 655 677 655 677 0.96
8 11 2.3e-06 0.00021 21.6 1.2 1 23 683 705 683 705 0.99
9 11 1.1e-05 0.001 19.4 0.2 1 23 711 733 711 733 0.98
10 11 0.002 0.18 12.4 4.2 1 23 739 761 739 761 0.98
11 11 0.00042 0.039 14.5 0.3 1 21 767 787 767 788 0.94

Sequence Information

Coding Sequence
ATGGAAGTCTCAAGTGAAGGAATTGCAGGGGAAAATTTCTTTGAAACCGTGGCGATAACTGGCGAAGAATGTCGATTATGTTTAATAAAATCAGACCAGATATTACAATTATTCGGAAGCCACGAAGAAGTGCCAAGGAAAGTAATGGCTTGTGCTGCTGTACAGATAGAAGAGGGTGATGGTCTTCCAACAATTATTTGTTACACATGTCGACGACTTCTAGACGTTTCCTATGAATTTAAATGTCAGGTTGAGAAGTCTGACGCCAGACTACGACAATTCTTGGAGATAAAGCCTCAATTGAATGCATATAACAATGCAATTCAACATTCTCTAGCACAATCAGTGAATCAAGTGATCACAGAAGCCATTGCTGATGAAATTCCACTCAATCCAACTGGAAATCAAGCTCAATTATCATCAGAAACGACAATGAACGAGGAAAATCATGAATCCACTACGATAATTACTGAATTAAACCATGAAAATACAATAATCTTTAATGTTACTGATTATCACAATGAGAAACAACATTCCAATGATCCTGGAGAACATTCTGCAGTAACTCAAATGTCTGTTAACCTTTCTCTGGCTGCTGAAACAAATAATGTTTTTGTTGAGAAGCTTGAGCCATACGTAGATACACATATTATTGACAGAGAAGTCATTAAAGAGGAAGTTCCTGGCTTGGCTGAGGAGAGTGAGCTCTCTGATGAGGATCAAGTCTATCAAGAGGAGATATTTCATGATCAACTACAGTTAAAAAACGAGGAAATGCTTGCTGAAGTCATAGAGAAGGTGGATTCATTGGGGAATGAAAAGCTTGAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGAAACCTTTGAGTTCTAGAACACTAAGACAAAAGTGTTCATACTGTATCAAGACATTTCCAACCAAGTCTGCTCTCCAAAGGCACATAAGTATTCACAGCAACAAGACTAAGTTACGTTATGTTTGTTATATGTGTGACAAACAATTTTCGACGATAAATAAACTAAAAAATCACGTTCTCAGCACTCACAACAGCTTGAAAAATGATGATAAAGGATTGCCAGAGGACAATGAAGCCAGTGGTGGTGAGGAAAAGTCACCAGAGAAAGTTGGGGCAGCTGTTGAGACGGCAAAAGTTGAAAAGAAAGGCTTAAAATTTGCTTGTAAATATTGTCCTAAACAATTTACCTATGAAAAACCATTTTTAACTCATGCTAAACGCCATCCGGAGTATCAGGGCCAAATTCGTGTGGAAGAGGAGTCACGAGAACGTGGATTTGATTCAGAGGATGATGATATGCCGTTGGAGGGATTGCAATGTACTCAATGTGGGAAATTATTTGCCACTAAGAGGAATTTGAAGAGGCATTTGTCGACTCATAGTGGTCTGAAATTTCATTGTACAACGTGTAATAAAGTATTTTCGAGACTGGACAAATTGAAGGAACATGAGCAGACTAAACATAAAGATGATTTGTTTGGACAATCAGATGAGGACGATGATGATGACACCGACAACGAGAATAAAAACAATGATGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCACAACAGGCCACACAAGTGTACAATGTGTCCAAAGGCCTTTGCCCAAGCTCAATCACTGACAAACCACATGGAGCGTCATAAACGTGTAAAAGACACCCAAAAACGTTTTCTCTGCGAAGTCTGCAGCAAGTGTTTCGCCCAAAGTGGATCACTGGTGGCCCATATGCGTACCCACACTGGTGTGAAGCCCTATGTATGCAATGTATGCAGCAGAGCCTTCACGAAAAGCACGTATTTGCAGTTGCACTTGCGCACACACAGCGGTGAAAAGCCCTACATTTGTCAGTACTGCAGCAGAGCATTTGCACGTGCAAATACATTGGCAAGACATATTACAATGCATACAGGAGAGGCCAAATACCATTGTCAAATATGTATGAAGTCTTTTAGACGTCTAACATCGCTGAACGAACACACTTATACTCATACAGGCCAACGGCCTTATGCCTGTAAAATCTGCACGAAAAGATACAACAATGCGGGTTCTCTTTATGCTCACACGAAGAAATGCAAAGCCCAACAACTCTCGAGCAACAGTGGAACCTTTACAGTGTCGACTGACGATGGAACTAATCAAAATGACAATTCTAGCTCGCCTATGTTGATTTATTCTCAACGAAAATTGACTGAGGAGACAACAGTCAATCAGGGAACGACGAATGCTCCATTTATTCTTAATAATGTTCCGAGTCAGAAACCACTGGCCTCTAATATTATTCAACCGTTCACTGTGGAGGAGCCAAATGTCTATACTGTCAATACTAAGCCATTTAAGACTCCGTACTACACAGTATATACAAGTATGTGA
Protein Sequence
MEVSSEGIAGENFFETVAITGEECRLCLIKSDQILQLFGSHEEVPRKVMACAAVQIEEGDGLPTIICYTCRRLLDVSYEFKCQVEKSDARLRQFLEIKPQLNAYNNAIQHSLAQSVNQVITEAIADEIPLNPTGNQAQLSSETTMNEENHESTTIITELNHENTIIFNVTDYHNEKQHSNDPGEHSAVTQMSVNLSLAAETNNVFVEKLEPYVDTHIIDREVIKEEVPGLAEESELSDEDQVYQEEIFHDQLQLKNEEMLAEVIEKVDSLGNEKLEXXXXXXXXXXXXXXXXXXXXXXXXXXXKPLSSRTLRQKCSYCIKTFPTKSALQRHISIHSNKTKLRYVCYMCDKQFSTINKLKNHVLSTHNSLKNDDKGLPEDNEASGGEEKSPEKVGAAVETAKVEKKGLKFACKYCPKQFTYEKPFLTHAKRHPEYQGQIRVEEESRERGFDSEDDDMPLEGLQCTQCGKLFATKRNLKRHLSTHSGLKFHCTTCNKVFSRLDKLKEHEQTKHKDDLFGQSDEDDDDDTDNENKNNDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHNRPHKCTMCPKAFAQAQSLTNHMERHKRVKDTQKRFLCEVCSKCFAQSGSLVAHMRTHTGVKPYVCNVCSRAFTKSTYLQLHLRTHSGEKPYICQYCSRAFARANTLARHITMHTGEAKYHCQICMKSFRRLTSLNEHTYTHTGQRPYACKICTKRYNNAGSLYAHTKKCKAQQLSSNSGTFTVSTDDGTNQNDNSSSPMLIYSQRKLTEETTVNQGTTNAPFILNNVPSQKPLASNIIQPFTVEEPNVYTVNTKPFKTPYYTVYTSM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-