Egla005506.1
Basic Information
- Insect
- Eugnorisma glareosa
- Gene Symbol
- grau
- Assembly
- GCA_947578425.1
- Location
- OX387959.1:20262683-20264302[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.0082 0.71 11.1 0.6 2 23 232 254 231 254 0.95 2 10 0.0054 0.46 11.6 1.0 2 21 260 279 259 280 0.92 3 10 0.17 15 6.9 1.0 1 23 302 324 302 324 0.95 4 10 0.00068 0.059 14.5 5.4 1 23 330 353 330 353 0.96 5 10 4.9 4.3e+02 2.3 3.0 2 23 361 382 360 382 0.90 6 10 0.0014 0.12 13.5 0.4 2 23 388 409 387 409 0.98 7 10 0.001 0.087 13.9 1.9 1 23 415 438 415 438 0.98 8 10 0.0049 0.42 11.8 0.8 1 23 444 466 444 466 0.98 9 10 0.027 2.4 9.4 0.1 3 23 473 493 472 493 0.97 10 10 3.3e-05 0.0028 18.6 2.9 1 23 498 521 498 521 0.96
Sequence Information
- Coding Sequence
- ATGAGCGAACAGAAGAAAAATATTAACTGTCGAGTTTGCTTACGGTATGATTTAGAAAGATCTCAGAAATGTTTGTCGTTGTTTGAAAAATACAACCATTCATTAATATCAGATAAAATTAAATTTGTAGCAAACGTTGAGATTAAGGAGAATGACGGATTACCCAGTAAAATATGTCCAGACTGCTTATTGCAACTTGAAACAGCCATAGTCTTCAAGCAAAAGTGTGAAACATCCAACAAGATCTTGCTAAGCATAGTTCAGCAGCCATCAAAAATATGTAAGGTTACCTTTCGAGTTCCAATTAAGAAGGAAGTAGATGTGGTATTTGGAAATAAAACAGATGAATATTCTAGCACTGAAGCAGAAATATCTAAAAAAGAAACTCAAATTGAAATAACTGCTAAAGAATTACATGACAATGAAAAATCCACTGATAAAGGATCTGATATCGAAACACTTGTCAGTAAAACTCAACAAGAAAAACCTGAACAAAAGGAACCTATAAATGTCTTACCTGTTAATGTAATACCTAAAAATGAGGAACCTGACTATGAAATATCTGACAATGAAGAACTTTTATTTGAGACACAACAAAATGATAAAATTGAAAAACTTGAGAATGTCGATGAAAATCATATATCTAATGATACGGCAGTAGTAAAACCGAGCAGGGCTATTGATTTAAAATTGATATGTGACGATTGTGGTGGCTCCTTTAAAAGTAAGTGTAAAATTGCTGTCCACTGGAAGAAAGTTCACCTACCCACCAAGCTAATTTGTCCATTCTGCAAAAGAATGTTTAAATCTTACAAAGCTTTCAATATACACAAGAAAAAGAAAACAAGAAGCTGTCAAGCTGCCTCTAATGTCCGCATTGAAGGTCTCGGCAAAAAAAGAGTATTTCACTGTAAGGATTGTGTCTATAGTACTAAAAGAATCAAGGATATGGATGCCCACTTGGTAATACACAGTGGAGTCAGGCGGTTTCAATGTAAGGACTGTTTGAAATGTTTCACTCAGCACGCCTCACTACAGGGACATCGGGAGTCCAAACACAAAGACTACAAATGTATCACAACATGCCACTTCTGTGGCAAACTCATTAAAGGTCGAAACAGATTCTACAAACATGTGTTGCAACATAAACCTAAATCAGTACAATGTGAGATCTGCAAGAAAATTTTAAAGAGTAAAGCAATTTTAATAAATCATATGAAAAGACACGATGAAGTTAAAAGTTACACCTGCGAAATATGTTCAGCCAACTTTTTCACAATGGGTGAACTTTGCAATCACCGCAGGAAGGTTCATTTTAAGGCTAAAACATTTAAGTGTGACATGTGTGAATACACAGCGTACACAGCAGGCTTATTAAAAACACATAAGTCTCGGCATACTCATAGTAACGTAGCATGTTTGCAGTGTGGCATGTTTTTGGAAAATGCCGAGAAGTTGGCTATACACCAGAAAAGGCATGCTGAAAAGAATTTCTGCTGTCCTGAGTGTGACAAAGGCTTCTTCCGTAGAGATTCAGTTCGTCGGCACATACTGAAAAAGCATTCAGAACCAAAAAAGTTGGGAAATTTTGTGTTAACTCTGAATCCTATTTTATCATAA
- Protein Sequence
- MSEQKKNINCRVCLRYDLERSQKCLSLFEKYNHSLISDKIKFVANVEIKENDGLPSKICPDCLLQLETAIVFKQKCETSNKILLSIVQQPSKICKVTFRVPIKKEVDVVFGNKTDEYSSTEAEISKKETQIEITAKELHDNEKSTDKGSDIETLVSKTQQEKPEQKEPINVLPVNVIPKNEEPDYEISDNEELLFETQQNDKIEKLENVDENHISNDTAVVKPSRAIDLKLICDDCGGSFKSKCKIAVHWKKVHLPTKLICPFCKRMFKSYKAFNIHKKKKTRSCQAASNVRIEGLGKKRVFHCKDCVYSTKRIKDMDAHLVIHSGVRRFQCKDCLKCFTQHASLQGHRESKHKDYKCITTCHFCGKLIKGRNRFYKHVLQHKPKSVQCEICKKILKSKAILINHMKRHDEVKSYTCEICSANFFTMGELCNHRRKVHFKAKTFKCDMCEYTAYTAGLLKTHKSRHTHSNVACLQCGMFLENAEKLAIHQKRHAEKNFCCPECDKGFFRRDSVRRHILKKHSEPKKLGNFVLTLNPILS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01533433;
- 90% Identity
- iTF_01065094;
- 80% Identity
- -