Basic Information

Insect: Eugnorisma glareosa
Gene Symbol: THAP3
Assembly: GCA_947578425.1
Location: OX387984.1:5813125-5833729[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 5 4.3e+02 2.3 3.4 1 19 357 375 357 379 0.89

2 10 0.0019 0.17 13.0 1.2 1 23 386 409 386 409 0.93

3 10 0.28 24 6.2 0.2 1 23 413 435 413 435 0.92

4 10 0.032 2.8 9.2 1.1 1 23 440 463 440 463 0.97

5 10 0.0016 0.14 13.3 0.2 1 23 467 490 467 490 0.96

6 10 1.3 1.1e+02 4.2 0.2 3 23 579 600 577 600 0.94

7 10 0.004 0.35 12.0 0.6 2 20 616 634 615 637 0.92

8 10 3e-05 0.0026 18.7 3.1 1 23 643 665 643 665 0.99

9 10 0.00023 0.02 15.9 2.8 1 23 672 694 672 694 0.98

10 10 3.9e-05 0.0034 18.4 0.7 1 23 700 723 700 723 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	5	4.3e+02	2.3	3.4	1	19	357	375	357	379	0.89
2	10	0.0019	0.17	13.0	1.2	1	23	386	409	386	409	0.93
3	10	0.28	24	6.2	0.2	1	23	413	435	413	435	0.92
4	10	0.032	2.8	9.2	1.1	1	23	440	463	440	463	0.97
5	10	0.0016	0.14	13.3	0.2	1	23	467	490	467	490	0.96
6	10	1.3	1.1e+02	4.2	0.2	3	23	579	600	577	600	0.94
7	10	0.004	0.35	12.0	0.6	2	20	616	634	615	637	0.92
8	10	3e-05	0.0026	18.7	3.1	1	23	643	665	643	665	0.99
9	10	0.00023	0.02	15.9	2.8	1	23	672	694	672	694	0.98
10	10	3.9e-05	0.0034	18.4	0.7	1	23	700	723	700	723	0.93

Sequence Information

Coding Sequence: ATGAGGTGCTGTGTTCAATATTGTCCTAATGACACCAGAAAAAATAACAAAAGCAATGGAATCACATTTCATCTGTTTCCAAAACCCCTTGAACTTCGCACAGCATGGCTGGAGTCCCTGGGCATGTCAGACTTTGAGCCCAAAGAAAGAAGCTGCATTTGCTCAGAACACTTCAGGAATGAGGACATTTACGAGACTAAAGCAGGCTTGAGGCGGATCAAGGGTGGAGCAGTGCCTGTCGTGATGCCTGAAACGGTAGATGATCTTGACGCGCCGGCCGCATTGAGGGCGTGCCGTATCTGCCTAGTAATGGACACAAAGATGTATCACATACGAGAATTTAAGCTGGATCAGATGTATGAACAAATCACTGGATTAATGGCAAGTTCAGAAGACCGATTCCCGCAGCGTATTTGCTGGGAATGCGCCGGCCGTCTGTCCGCGGCGAATAGCTTCAGAAATAAGGCGTTACGCAGCAGCTCCGTGATGTATGACATTCTGCAAGCTGGTCTTTATATAAAAATCCGTGACATAAAAAAAGTTAATAGAAAAAAACACAAACTAACTACAAATTTAGTTCAACAAATATATGAAGATGGTGATTTCGACCTACGCATTAAAGACTTAAGTATCAAAACTGAAGAAACGCGGGATATGTGTGAAACCATACCCATTGATACAGAAGAAATTGATGTAAAAAGCTTAGCACCTATAAACGAGATCGAAGTTAAAGCTGAATCTGCAAACAATGAAATATTTTTCGAAGCATTTGATGATAATTTTGATGATGACGATGACAAGGTCTTAAGTGAAGTCTATGTCGAGAAGAAGGAGGTGCCTCAAGTGAAGAAGAAAAAGGACAAAGTGGTTAGAAGAGTCAAACAGAAGAAGGTTGAGGAAGATGATGACCCGGATACTGCGACTGATAGGTACAAAACAACTGAAATAAAACGCCGTCGAAACGTCGAATTCGACGAGTCTCTATTCACGATTACATCGTTAACTTACGACGAGCAAATTGAAGAGATTCTCAAACGGCAGGAGTCTTACAACTACACCAGCGCCCCCTTCAAGTGCACCGTGTGCTATAGAGGGTTCCAGATCAAAGATCGGTTCACTGCGCATTGTGTGCGGCATACCGAGCAATGCGGTGCCTACGAATGTTTCATCTGTAAAACGAGATTGAAAACGAGTCGCGCGCTGCGGAAACATTTGACGGCGCAACATACGGAACAATATAGCTGTAAGGGTTGTCCATTTGTCACTAGGAATAGAGGCGTAGCGAGAGAACATGAGAAATGGCATGGCGGGACGAAGTACCAGTGTCCGCACTGCGCTAGTTCGTTTGaCAAAATAACGACATACATGGGCCATATTCGCATAAAGCATGTGTCGGACTTTGTGTGTGAACTCTGCGGGTACACGTTTGTCAGTGCGAAGGGTATAGCTGTACATAAGAAGAAGAAACATCGTGTTGATAAGGAGTTAACATTAGAGGGGCCATACTGCGACACGTGTGATGTGAAGTTCTTAGACGAAGAGGCTCATGAGCGGCATCTGAAGTTGTCGGCAAGACATAGCAGTGATCATGACCCCAACCGGATCCGGAACGACTCGCAAAGCATGAACGCAGAACGCAACGGTCGGGTGATGCGTCGCATAGAACGCAGGCCGGTCATACACCCGCGCGCGCCCAGCGATAGCGACCAACACGACCCGCAGACTCCCGTCAACTGTGAACAGTGCGGCATACAACTCCGCGACCTGCGAGTATACGCACAACACTTCAGACGGATGCACCCGGACAAGAACCGAACCAAGTACCCCGCGATGAAGACCCCCTGCATGTGTGAACAGTGCGGCAAGATATTCCAGAGTATGGCCCTCCTAAAAGACCACATGTGGGTCCACACAGGAGAGAAACGCTTCAAATGTGACCGCTGCACCAAGAGCTTTACACAGAAGACGAATCTAGTGTTCCATATGAGGGTCCATAGCGCTTCGCGACCGAGCTACGAGTGTCCGCTGTGCGGGAAACACTTCGCGTTCTTCAATAACAGGAGACGTCATATGTTTATCCACACCGGCCTCAAGCCCTTCAAATGCGACACGTGCGGCAAGAGCTTCACGACGGCGGGCGAGCAGCGCGCGCACGTGGAGCACGTGCACATGAAGAAGCCCTGGCCCAAGCGAGCGCGCACCAGGCACCGCGACTGGAAGTGCGACGAGCGCAGCGTGGAGGACTGA
Protein Sequence: MRCCVQYCPNDTRKNNKSNGITFHLFPKPLELRTAWLESLGMSDFEPKERSCICSEHFRNEDIYETKAGLRRIKGGAVPVVMPETVDDLDAPAALRACRICLVMDTKMYHIREFKLDQMYEQITGLMASSEDRFPQRICWECAGRLSAANSFRNKALRSSSVMYDILQAGLYIKIRDIKKVNRKKHKLTTNLVQQIYEDGDFDLRIKDLSIKTEETRDMCETIPIDTEEIDVKSLAPINEIEVKAESANNEIFFEAFDDNFDDDDDKVLSEVYVEKKEVPQVKKKKDKVVRRVKQKKVEEDDDPDTATDRYKTTEIKRRRNVEFDESLFTITSLTYDEQIEEILKRQESYNYTSAPFKCTVCYRGFQIKDRFTAHCVRHTEQCGAYECFICKTRLKTSRALRKHLTAQHTEQYSCKGCPFVTRNRGVAREHEKWHGGTKYQCPHCASSFDKITTYMGHIRIKHVSDFVCELCGYTFVSAKGIAVHKKKKHRVDKELTLEGPYCDTCDVKFLDEEAHERHLKLSARHSSDHDPNRIRNDSQSMNAERNGRVMRRIERRPVIHPRAPSDSDQHDPQTPVNCEQCGIQLRDLRVYAQHFRRMHPDKNRTKYPAMKTPCMCEQCGKIFQSMALLKDHMWVHTGEKRFKCDRCTKSFTQKTNLVFHMRVHSASRPSYECPLCGKHFAFFNNRRRHMFIHTGLKPFKCDTCGKSFTTAGEQRAHVEHVHMKKPWPKRARTRHRDWKCDERSVED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01534918;
90% Identity: iTF_00928774;
80% Identity: iTF_00685511;