Egla016774.1
Basic Information
- Insect
- Eugnorisma glareosa
- Gene Symbol
- -
- Assembly
- GCA_947578425.1
- Location
- OX387984.1:6469070-6479827[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.33 29 6.0 0.3 1 20 273 292 273 295 0.74 2 9 0.00038 0.033 15.3 2.3 1 23 302 324 302 324 0.96 3 9 0.35 30 5.9 4.3 1 19 328 346 328 349 0.89 4 9 0.00018 0.015 16.3 0.9 3 23 359 379 357 379 0.97 5 9 0.00042 0.037 15.1 4.5 1 23 385 407 385 407 0.98 6 9 3.1e-05 0.0027 18.7 0.7 1 23 413 435 413 435 0.97 7 9 0.0065 0.57 11.4 3.0 1 21 441 461 441 462 0.95 8 9 8.4e-05 0.0073 17.3 1.9 1 23 474 497 474 497 0.96 9 9 2.2e-06 0.00019 22.3 5.3 1 21 501 521 501 524 0.95
Sequence Information
- Coding Sequence
- ATGGCAGAAAGAAACACAAAAATGTGTCACATTTGTCTAGCAAGCGACATAGAAAGTAATATTAGTGATTCATCGTGTTATTCTAAGTTTTTCATTCATGTTATGCGTTTGAAATACTTGAAAGAAAAGTTAATGCTTTGCATGTGGTGCAAAGCTGCATTGAGACGAGCAATTGCTGTTTTGAAATTGGCATTGGAATCGGGAAAAGCGAAAGAAAATAAGAGTCCATCTGATGTCAGACCTAAAAGATTACACACACTGAATTTTATTCACAATTCGCACATAGACATACCACCTCTTTTAATATTATACCAAGATTGTAAAACTGAAAATATTACTCAAGAAATGGAAGAAAATATTAATCCTTTACTTGAAATACAAGATAATGATGAAATGTCTTTGAAAGCAAATAGAAAAACCATGAAATCAACTGAAGTTTTAAATGAAGAATTAATTTCAAGTAAATACCATCATATTTTTGAAAATGAACCTACAACTAAAAAAATAAATAAAAAGGCAATGAAATCCACCAATACTATAAATCAAGAATCAATTTCAAACATAGAACAAGATTATTTTGAAAATGAAATTGCAGCTAAAAAAATAAATAATAGTATTACGAAATCTACTGATATTCTAAACAAAGAATCAGTTTCAAAAGTAGAACAAGAATTACAAGAAAATGGAATTTTAACTAAGAAAAGAAAGAAAAAAGACTTTGATTTCAATGAATTGAAGTTTGAAGTAGAGTATTTGACTTTTGAAGAGCAGTTGAAAGAACTTGAATTGAAAAAGTTGAAATATAAAGATTTTAAGTTTCAATGTGATGAATGTGGTATGGGGTTTCTTACTAGTGATATATTTGAAGAACATAAAGTTAGACATTCAAAGCTATCCGGCGACCACAAATGTTCCATATGCGGTCTCCACTTCAAATCTCGCGACGTACTGTCTCAACACTTGCTGGCACATAGGCGGCGGTACTGCTGCTCGCTGTGTGCGCGCGTGTTCACTAGATGGTCGCATTGTGTCGCACACAGCTACAAGTGCGGCGCAGTTGTTACACCGACAGCTTGTGCCCACTGTGCTAAGCTGTTTAGCAATGAATATTCCCTGAAGATTCACATGAAAGTTCATAAAACTGATAAGAAGTATTGTTGTGACCAGTGCGATAGAAAATTTGCTAGCAAGCAACGGTTAACAGTGCATAAGAGATCCCATTCTGGTGTAAAGCCGTTCTCGTGCTTGGTGTGCTCGCGCGCCTTTGCGACTTGCTCAAACTTACGCGCGCACACTGCGGTGCATGACCCCACAAGTCAGTTCTACTGTGTGGAGTGTCACACGTATTATAAGACGGAGAAGAGTCTTAAACGGCATTATAAGGAGTCGGCGAAGCATACGGATTTGAAGAGTGATAAGTACTCGTGTAAAGAGTGTAACAAACAGTTTTCCACCGAAAAGTCTATGAACTATCATATTAGTATCAGACATGATACTGAACACCGCTGTTCTCAGTGTGATAAGACGTTCTCCAACAATTCGAACCTCAATAAACATATAAAATGTATTCATACGGCAAAATAA
- Protein Sequence
- MAERNTKMCHICLASDIESNISDSSCYSKFFIHVMRLKYLKEKLMLCMWCKAALRRAIAVLKLALESGKAKENKSPSDVRPKRLHTLNFIHNSHIDIPPLLILYQDCKTENITQEMEENINPLLEIQDNDEMSLKANRKTMKSTEVLNEELISSKYHHIFENEPTTKKINKKAMKSTNTINQESISNIEQDYFENEIAAKKINNSITKSTDILNKESVSKVEQELQENGILTKKRKKKDFDFNELKFEVEYLTFEEQLKELELKKLKYKDFKFQCDECGMGFLTSDIFEEHKVRHSKLSGDHKCSICGLHFKSRDVLSQHLLAHRRRYCCSLCARVFTRWSHCVAHSYKCGAVVTPTACAHCAKLFSNEYSLKIHMKVHKTDKKYCCDQCDRKFASKQRLTVHKRSHSGVKPFSCLVCSRAFATCSNLRAHTAVHDPTSQFYCVECHTYYKTEKSLKRHYKESAKHTDLKSDKYSCKECNKQFSTEKSMNYHISIRHDTEHRCSQCDKTFSNNSNLNKHIKCIHTAK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01533511;
- 90% Identity
- -
- 80% Identity
- -