Egla002317.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Eugnorisma glareosa
Gene Symbol
-
Assembly
GCA_947578425.1
Location
OX387982.1:1005377-1007012[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.0037 0.32 12.1 0.4 1 23 152 175 152 175 0.93
2 10 0.13 11 7.3 0.5 2 23 179 201 178 201 0.92
3 10 0.057 4.9 8.4 1.8 1 23 203 226 203 226 0.96
4 10 1.4e-06 0.00012 23.0 0.5 1 23 229 251 229 251 0.98
5 10 0.00015 0.013 16.5 0.4 2 21 256 275 255 276 0.93
6 10 4.5e-05 0.0039 18.2 0.3 1 23 295 318 295 318 0.93
7 10 4.7e-06 0.00041 21.3 2.5 1 23 324 346 324 346 0.97
8 10 0.00031 0.027 15.5 1.2 1 23 352 374 352 374 0.99
9 10 0.00069 0.06 14.4 0.3 1 23 380 403 380 403 0.95
10 10 0.0003 0.026 15.6 3.3 2 23 409 430 408 431 0.94

Sequence Information

Coding Sequence
ATGAAAGAAGAGTCAGAATTAAATGTGCTTGTGTCTAATGTACTAAGCGAAAATCGGTACAGCCACTGCAGGTTATGCCTAGAGGATATTCAAGAACATTACATTCGTTTTCATGATTCTGTGTCGCTGGACTCCACGAGTGGGGCTTACCTAACGCTTTCTGAAATCCTAACGAAACTGTTAGGGGCTGAAGTCTGTGAAGAGATTGCTGGGATTGATGCAGTGTGTATGCCATGTGTAGACAAAGCACTTGATTCACTCAAGTTCCTACAATCTTGTGAAATATCAACCAATTTACTCCACAATGTCTTCAATAATCTCTCCAATGCACTGACTGCTGATATTGACACAAGTTCAGATCAAACCCTTTACATAACAGTCAGGGAACATGAGTCTACTCTTGTTTTGGTGAAAAATGAAGCAAAGAAGCAGAAATCCCAATTAAATAAGATTTTCCAGTGCACTAAATGCAAAGAACGATTTGCAGACATATTGGAGCTCCGAGTTCACAACATATCAACTCATGCTATACTCACATGTGAGAAATGCCATGATAATTTAAGTGATGAGAGTGAACTGACTGCACATGAAGACAGTCAGCATATTTATGACTGCCCTGAATGTAATCAGTTTAAGTGCACTGAGGAAAGCTTGAAACAACATCGGGATACAGTCCATGGAGTATTTGTATGTAAGGACTGTGGCAAGCCTTTCAAAAGTTTAGAAAAGCTGCAGATCCATGAACAAAAACACATCTCCAAAAGTGAATGTCCCAAATGTGGCAAAAGCTACAACACCAAAGGATTCTTCTTAAAACATGTCAAGTTATGTCTGGAAGACATGTTGGACCCACATCCAATAAGGAGTAAAATTGAGAAGACATATTTTTGTGAGAAGTGTGGAAAGGGCTACAGTACTCCTGGAGGATTACGGGTCCATAATAGATTTATTCATGGTAATGCAACACCACACACTTGTAAATACTGTGATAAACAGTTTACTGCTCCAAGTTACTTAAAGGTTCACATGGTTAAACACACTGGTGAAAAGAATTTCAAGTGTGACTTGTGTAGTAGACTGTTTGTTTCTAAAGAGGCATTGTTGTACCATACCAGAAGGCACACAGGGGACAAACCATATAGTTGCACGGTGTGTGATGAGAAGTTTGTGAATGCCTCAGCTAGAGCTGAGCATATAAAGTTCAAACATGTTGGTCCAACCCTTATGTGTGAGATATGCTCTCGCAAATTCTTTACACCTAACTTTTTGAAGCAGCATATAAAGAAACATCATGATCCTTCTAACAAGCTGTATGCTGGCAGGAGTCTAATACCGCCCAATGTTCCAGCTGTAGAAAATATGAGAGTTAGGTTAGTAGACTTATAA
Protein Sequence
MKEESELNVLVSNVLSENRYSHCRLCLEDIQEHYIRFHDSVSLDSTSGAYLTLSEILTKLLGAEVCEEIAGIDAVCMPCVDKALDSLKFLQSCEISTNLLHNVFNNLSNALTADIDTSSDQTLYITVREHESTLVLVKNEAKKQKSQLNKIFQCTKCKERFADILELRVHNISTHAILTCEKCHDNLSDESELTAHEDSQHIYDCPECNQFKCTEESLKQHRDTVHGVFVCKDCGKPFKSLEKLQIHEQKHISKSECPKCGKSYNTKGFFLKHVKLCLEDMLDPHPIRSKIEKTYFCEKCGKGYSTPGGLRVHNRFIHGNATPHTCKYCDKQFTAPSYLKVHMVKHTGEKNFKCDLCSRLFVSKEALLYHTRRHTGDKPYSCTVCDEKFVNASARAEHIKFKHVGPTLMCEICSRKFFTPNFLKQHIKKHHDPSNKLYAGRSLIPPNVPAVENMRVRLVDL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01425368;
90% Identity
iTF_01085691;
80% Identity
-