Egla020851.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Eugnorisma glareosa
Gene Symbol
L
Assembly
GCA_947578425.1
Location
OX387958.1:11101469-11106721[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.53 46 5.4 5.8 1 23 3 25 3 25 0.97
2 16 7.2e-06 0.00062 20.7 4.1 1 23 31 53 31 53 0.99
3 16 2.2e-05 0.0019 19.1 0.1 1 23 59 81 59 81 0.98
4 16 0.001 0.088 13.9 0.0 2 23 97 119 96 119 0.94
5 16 5.1 4.4e+02 2.3 0.1 9 23 150 165 146 165 0.93
6 16 0.26 22 6.4 0.0 3 23 217 237 216 237 0.97
7 16 0.14 12 7.2 0.0 3 23 251 271 250 271 0.91
8 16 0.00047 0.04 15.0 0.3 1 23 279 302 279 302 0.95
9 16 0.029 2.5 9.3 0.0 1 23 307 330 307 330 0.92
10 16 0.012 1 10.6 0.1 1 23 391 415 391 416 0.94
11 16 0.00017 0.015 16.4 0.1 2 23 479 500 478 500 0.96
12 16 0.049 4.3 8.6 0.0 1 23 508 530 508 530 0.98
13 16 1.7 1.4e+02 3.8 0.8 2 23 538 559 537 560 0.94
14 16 0.74 64 4.9 0.3 1 23 637 659 637 659 0.94
15 16 0.003 0.26 12.5 0.1 1 20 667 686 667 689 0.95
16 16 0.13 11 7.3 0.3 1 23 696 718 696 718 0.94

Sequence Information

Coding Sequence
ATGCCGTTCAGGTGTGAGTTCTGCTCGCGCCTGTTCAAGCACAAGCGCTCTCGCGACCGCCACGTCAAGCTGCACACCGGGGACCGCAAGTACCGCTGTGCACACTGCGAATCTGCCTTCTCCAGGAGCGACCACTTGAAGATCCACATGAAGACGCACGACAACCAGAAGCCGTTCCAGTGTACCGTCTGCAATCGAGGGTACAACACGGCAGCCGCTCTGACGTCACACATGCAGGGACACAAGAGGGACCGTGAGGGTCGGGAGCCTGACAGACGCAGGGCTCTGCGCTGTCTGCGGTGCGGGGATGCCTTCCGACGACCAGACCTGCTGCAGGCGCACATGGTGAGCGCACACGGCGTGGACACTCCCACGATGACTCCACCACGACGCGTTGCTTCTCAGCCGCCGCCCACGCTACTTGCCTGCATCTACTGCACTCGTGACACATTTACCAGTATGGAGCAGTTACAACTTCATGTACGGGCAGCACACTCAGCCCTGCTGAATGGAGAAGGACCAGTACAAGTAGATCAGCCTGCGCCCACTGATTTAAGCCGACGGGCGCCTGAGGAAGTGCCTCCAGTCAAACGTCCTCGCTCCGGCTCTGGCACACCACAAACAAACTTATCACCGAGCACACTGCTCTGCAATCAATGTGATGCTGCGCTCCCAGATTTTGAAGCATTTCGGGCTCATTTGAAAGGTCATATTGAAGAAGGAGGGGAACTGCGATCAAGTCCTGCTCCTTGCGTTCACTGTGGCGCTACGTTCGCGGACGCTGCGGCCTCGGAGCGTCACCTCACAGCGCATTACCTGGCGGTCTCATGCGAGTACACCTGCCACAGCTGCGCTCGGAGCTTCGCTGCTCCTGATGACTTGCAGAAACATTTGCTAGAACTGCACGCGCATCATCTGTATAGATGCGCTCTTTGCAAGGAGGTTTTTGATTCGAAAGTGGCGATTCAGGTGCATTTCGCGGTGGCACATAGTGGTGAAAACAAGGTTTGGGTATGTCGTTCTTGCGGTGCGAGCGCGGGCGCTCTCCGCTCGGAGGCCGAGGGCGCGGCCCATGTACGCTCTCTTCACGCGGCCGCGGCCCCTCGATGTGCATGTGGAGCCCTACTCGGCAGTGGAGTCGCTGCGAGGACCCCTCGACCACACCGCGCATATCGGTGCCCAGTGCCCGCCTGCAATGACGCATTTGCTGTGCAGTACTTGCTTGAACGACATATGCAAGCTCATCATGCAATGCAACAGCAGGTTCTAAACGGTGATTTACCAAGAACAAAACGAATGGAGTCCACTAACGGCGGCGAAGGCGCTGATGACGCGCGGTCCCCATGCTCCCCTGGAGCTGAAGGCGGTGGTGTGACCACAGCGGTGGTAGCAGCAAGTGAGGAGCGAAGGCGGAAGAACGGTGCCGTAGCCTTGCAGTGTGCTTACTGCGGGGAGCGCACGAGGAGTCGGGCAGAACTAGAGGCGCACACACGAGCTCATTCGGGAGCCGCGGCGGCGAGGCACAAGTGTCTGATCTGTGATGAAGTGCTGCCGTCTGCGGCGGTGCTTGCTGAGCATAAGCTCACACACTGCAAAGTGGTATCCGGCGATACGTGCTCCCGCTGCCGCGCGCGGCTGGTGTCTGAGGACTCGTTCCTGGGCCACATGGCGCGGCACCACCCCGCGCTGCCGGCGCCGTGCGTCGTGTGCCGACAGACCCTCGCCTCGGAAGCGGAGGCTAGACTTCACGCACGATTCCATCTGCGACCCGGGGAGGATGAGCAAAGGTGCGCCATATGTCTCCGCGCGCTGCCGGAGGGCGAGGCGGGCTCGGGCGCGCGCGCGTGCTCCGCGTGCTACGCGCGCCACGCGGCGCCGCGCCCCCCGCGCCCCGCGCCGCCCGCCGACCACGACTGCCGCCTGTGCCGCCGCGCGCTGGGCTCCCCCACACGCCTGCAGGCGCATCTCATCGAGCACACGTTCGCTGGTATCGGCGCTTTCACTTGCTACCTGTGCTCCGCGGTCTTCACGAGCGCGGCCGGCCTGCAGCGCCACCTGCCGGAACATGCGTCCGCGCCGCGACCCTACGATTGCGCTAGATGTGGTCTCAAGTTCTTTTTCCGAGCAGAACTTGATAATCACGCATTCGTTCATCTTGAAGAAGCAGAGATTGCTCAGCGAGCTTTTTATGAAGCGTACGCTCGCGGTGCTGCGTCAGCGTGGGCTGCGCTGGCACCGCCGGAACCGCGAACGTCTCCGCCACAAGTTGAGGTCAAGCGCGAGCCGGAGATCAAAGAAGAGCGAGGAACTGACGAGTATATTGAGGTGTCGTCCCCGCCCCCCGTGGCCCCGGCACCCGCGCCCCCCGCCCCGCCCTCGCCCGCACTGGTCGTGAAGCAAGAGAAGCCTGACGAGGAGTAG
Protein Sequence
MPFRCEFCSRLFKHKRSRDRHVKLHTGDRKYRCAHCESAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQGHKRDREGREPDRRRALRCLRCGDAFRRPDLLQAHMVSAHGVDTPTMTPPRRVASQPPPTLLACIYCTRDTFTSMEQLQLHVRAAHSALLNGEGPVQVDQPAPTDLSRRAPEEVPPVKRPRSGSGTPQTNLSPSTLLCNQCDAALPDFEAFRAHLKGHIEEGGELRSSPAPCVHCGATFADAAASERHLTAHYLAVSCEYTCHSCARSFAAPDDLQKHLLELHAHHLYRCALCKEVFDSKVAIQVHFAVAHSGENKVWVCRSCGASAGALRSEAEGAAHVRSLHAAAAPRCACGALLGSGVAARTPRPHRAYRCPVPACNDAFAVQYLLERHMQAHHAMQQQVLNGDLPRTKRMESTNGGEGADDARSPCSPGAEGGGVTTAVVAASEERRRKNGAVALQCAYCGERTRSRAELEAHTRAHSGAAAARHKCLICDEVLPSAAVLAEHKLTHCKVVSGDTCSRCRARLVSEDSFLGHMARHHPALPAPCVVCRQTLASEAEARLHARFHLRPGEDEQRCAICLRALPEGEAGSGARACSACYARHAAPRPPRPAPPADHDCRLCRRALGSPTRLQAHLIEHTFAGIGAFTCYLCSAVFTSAAGLQRHLPEHASAPRPYDCARCGLKFFFRAELDNHAFVHLEEAEIAQRAFYEAYARGAASAWAALAPPEPRTSPPQVEVKREPEIKEERGTDEYIEVSSPPPVAPAPAPPAPPSPALVVKQEKPDEE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01437318;
90% Identity
iTF_00822228;
80% Identity
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