Basic Information

Gene Symbol
-
Assembly
GCA_001483705.1
Location
NW:947096-952595[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 3.4e-08 1.8e-06 27.2 1.7 1 23 161 183 161 183 0.98
2 16 0.12 6.6 6.6 1.6 1 23 189 211 189 211 0.97
3 16 1.9e-05 0.0011 18.5 3.3 1 23 218 241 218 241 0.97
4 16 2.2e-07 1.2e-05 24.7 2.7 1 23 247 269 247 269 0.99
5 16 0.0099 0.54 10.0 1.1 2 21 275 294 274 295 0.92
6 16 5.9e-07 3.2e-05 23.3 3.2 1 23 331 353 331 353 0.99
7 16 4.9e-05 0.0026 17.3 0.7 1 23 357 379 357 379 0.97
8 16 4.9e-05 0.0026 17.3 0.9 1 23 511 534 511 534 0.97
9 16 2.9e-05 0.0016 18.0 4.6 1 23 540 562 540 562 0.98
10 16 0.0096 0.52 10.1 7.6 1 23 571 594 571 594 0.94
11 16 0.00074 0.04 13.6 1.2 1 23 600 622 600 622 0.95
12 16 9.8e-06 0.00053 19.5 2.4 1 23 627 650 627 650 0.96
13 16 0.00072 0.039 13.6 1.2 1 23 656 678 656 678 0.98
14 16 9.3e-08 5e-06 25.8 0.7 1 23 682 704 682 704 0.99
15 16 0.016 0.86 9.4 6.7 1 23 710 732 710 732 0.99
16 16 4.1e-05 0.0022 17.5 3.2 1 23 738 760 738 760 0.97

Sequence Information

Coding Sequence
ATGTTTTGGTTAACGGGGCTAAAAATTCACGAAAATGTGAAGGTAATAGCTGGAGGTAGTACCGAAACTTTCCAAAATCGAGGTTTTACAACCCTCGCAGGAAGAAAACACAGTTCGTTAATTTCTATCCTAGCAGATATCGATACTCTgtCGACACCGCGTGATCCGCTCGAGCAAACGTACCTCGTCGTGCAAAATGTCGATAAGTACTTCCTGCTACCCGTCCAACACAACGTACCGACGCAGAAACAGCAGGAACAGGTACCCACCGCGCCGGAAGTGAACGTTAAGACCGAAGTGCAGGAAGACGTAGCTCAAGAAACACGTGAACAGCCACCGGCCGAGGGACTCAAACTGGACGACAGGTCCCGATTACCTCCAGCATTACCTATTCAGCTACCTTTACAGTTGTCGCAGTGGTTGGACCAGTATTCCAGTTCAGAGGACACGATGACGAAGACTATGGGCACCGAGAAGATATTCACCTGCGACTACTGTCCAAAGGCCTTCAGGCAAAAGTACTCTCTGCAGAGACACCAGGCGACTCACAGCAACACGAGGACCTTCGAGTGTTCGGTGTGTCAGCAGTTGCTGAAGACCAAGAGGACACTGCGATTTCACATGATGCTGCACGAGGACAGCGGTAAGATATTCCAGTGTACCGACTGTGGCTTCATGTCGAAGAGGAACCACAGTCTGAAGCGTCATCAGATCAGGATTCACTCGAAATACTTCAATTACAAGTGTCCACATTGTCCGAAGATGTTCAAGCTGAACGCCGACTTGAAGAGACACCAAATGAAACATGTAATCGCGCCGTGTTACTGCGAGGTCTGCGGGAAGATGTATCAGAACGAGTTCTTCCTGCGAGTGCACCAAACCATGGGCAAGAATCGCAGAACCACCTGCTGTTATACGGCTGTGCAGAATGGAAGGATCATAGTGAAGGCAACGTCTGCCAGGAATAAGAAGGGCGACGTGAAGCGAGTGTTCAAATGCTCACAGTGCAAATGGCGATTCAGCAGTTGGAAGTTACTGCGCAAACATATGCAACGGCACTTCCTTAGCTATAACTGTGAGACTTGCGGTGCTGTGTTTAAGTATAAGGCCTCGTTTCTGAAGCATCAGGATTCACACAAAGAGGAACAGTTGGAGTCGACGCTGCCTTTAAGATTGAAGAACGAAATCATCGTTGGTGATCAAACGAAAGAGCAGTTAATAGCTTTGCACAAGTCATCAAGCATTCTCCAAAGAAGAATCGCGTTTCAAGTCTTGAAAAATTGCAAACGCGGAGGCAACTGGCGTTTGAAGCCTTGCAACCCTTCTGGTTGCAtcgaaacgaaaaatatttctacTAATTGCACAAATTTCGAGCGAAGGAAGGTAAACAACGAAGAGAGGAATTCATCGAGAAATCCAGCAAGCAAGAAGTTACAGTTGAATTCGAACAATTGTTCAGATAACTTGCACAACAACGAGAAAGATTCTACGCAGCAAGAAGACTTGTACAAGAAACTTCACGATGGCACTTACACTTGTGATATTTGTCAGACGACTTTCGAACAGAAGAGCAAAATTCTTCGCCATATTATCAGTAAGCATAGTTTCCATCGACCCTTCAAGTGTTTAACTTGCGATAAAACGTTCAAATACAAATGCGACCTGAAGGCTCATCGACTGGTCCACCAGGACGTCGATACCAGTTTGTTACATTGTTGTGACAAATGCGATTATCGTACAAAAACAAAGAACAATCTCAAGTCCCATTACATCAGGAGACACACAGATGATTATAAATTCGCATGTGAACACTGTGGAAAACGCTTCAAGATGGAATGGGACCTGAAATTCCACATTGGAACTCACAGCAGTTCCCAGCATATGTGTGATATTTGTGGAAAATTCTATACGAGTAATTATTCTTTGTATAAGCACAGAAAAGTAGCCCACTTGAACGAGTATAAGTTTCAGTGTAAAGTTTGCAATAAGAGACTCTTGACGCAGGAGAATTTGGACAATCACAtgcaacagcacagtagaacgtacgAATGCAAAGAATGTGGAAAGGTATTTGCCTCGAAAAGGTATCTAGTAACACATATGACTACGCATACGGGTGTGAAGCCATATACTTGTCACATTTGTATGAAGAACTTTCGAACGTCTCATATGAGGAACACGCACTTGCTGACACATTCCGCGGAAAGGCCACATATCTGTGATCTGTGTGGGCAGTCCTTTAAGAGGAGATACTACATGATAGAACACCGAAGGAAACATCCTGACGCCCATTTGTCCTCGCCTCCTGTGCCTCTTGGGAAAAAGAAAGGTATCGCTGATTTGGAAGCAGAAACTGTCACTGATTTCCAAGCAGTGATTCCTTTCTACCATAACGATTAG
Protein Sequence
MFWLTGLKIHENVKVIAGGSTETFQNRGFTTLAGRKHSSLISILADIDTLSTPRDPLEQTYLVVQNVDKYFLLPVQHNVPTQKQQEQVPTAPEVNVKTEVQEDVAQETREQPPAEGLKLDDRSRLPPALPIQLPLQLSQWLDQYSSSEDTMTKTMGTEKIFTCDYCPKAFRQKYSLQRHQATHSNTRTFECSVCQQLLKTKRTLRFHMMLHEDSGKIFQCTDCGFMSKRNHSLKRHQIRIHSKYFNYKCPHCPKMFKLNADLKRHQMKHVIAPCYCEVCGKMYQNEFFLRVHQTMGKNRRTTCCYTAVQNGRIIVKATSARNKKGDVKRVFKCSQCKWRFSSWKLLRKHMQRHFLSYNCETCGAVFKYKASFLKHQDSHKEEQLESTLPLRLKNEIIVGDQTKEQLIALHKSSSILQRRIAFQVLKNCKRGGNWRLKPCNPSGCIETKNISTNCTNFERRKVNNEERNSSRNPASKKLQLNSNNCSDNLHNNEKDSTQQEDLYKKLHDGTYTCDICQTTFEQKSKILRHIISKHSFHRPFKCLTCDKTFKYKCDLKAHRLVHQDVDTSLLHCCDKCDYRTKTKNNLKSHYIRRHTDDYKFACEHCGKRFKMEWDLKFHIGTHSSSQHMCDICGKFYTSNYSLYKHRKVAHLNEYKFQCKVCNKRLLTQENLDNHMQQHSRTYECKECGKVFASKRYLVTHMTTHTGVKPYTCHICMKNFRTSHMRNTHLLTHSAERPHICDLCGQSFKRRYYMIEHRRKHPDAHLSSPPVPLGKKKGIADLEAETVTDFQAVIPFYHND

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-