Emer016226.1
Basic Information
- Insect
- Eudonia mercurella
- Gene Symbol
- zfh1
- Assembly
- GCA_963082485.1
- Location
- OY720030.1:455201-465296[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 8.7 9.9e+02 1.7 1.4 3 21 455 473 453 477 0.91 2 13 0.052 6 8.7 1.0 1 19 498 516 498 521 0.97 3 13 0.0053 0.61 11.8 3.1 1 23 536 559 536 559 0.97 4 13 0.27 31 6.5 2.8 1 22 564 585 564 588 0.89 5 13 3.4 3.9e+02 3.0 1.4 2 23 609 633 608 633 0.75 6 13 0.13 15 7.4 0.3 2 20 639 657 638 659 0.80 7 13 0.00018 0.021 16.5 1.0 1 23 718 739 718 739 0.97 8 13 0.0002 0.023 16.3 2.5 1 23 745 768 745 768 0.95 9 13 0.00014 0.016 16.8 2.0 2 19 794 811 793 814 0.94 10 13 0.027 3.1 9.6 0.3 3 23 818 840 817 840 0.95 11 13 0.28 32 6.4 7.6 1 21 847 867 847 869 0.95 12 13 0.0019 0.21 13.3 2.2 3 21 877 895 875 900 0.93 13 13 0.0059 0.68 11.7 0.9 1 23 906 929 906 929 0.96
Sequence Information
- Coding Sequence
- ATGCTGTCGCCGCGCGATGACGACGACGATGACAGCCACCTCTGCATCAAATGCAACGCCACCGTCGTCGGGCTCGACAACTACGTCAAGCACCGTAAGCAGAGGTGCGGCAAGATCGCCAAGCCCGACACTTCTAAGGCGGATATCTCGAGCATTGACACGTTAGACCCGACCTACAGCCTCGGCGCTGATGTCTTCTTCCAGTCTCTGGAATTGCAGAGCAGCGTCAAAAAAACTTCTTTATCGAGATTGACGCCACCCATACCGATAACGAAAGCAGTTTTAGATACAAAAAACACAATGGTTGAAGCTTCTTCGTCTAGAGATCTACCACGAATGAGCCCTTTAGAAACTAATTTGAGAGAAGAAGACTGGATCGGGGGCCACTCGCTAAGAATCGGAGGAAACGAAGACAATCAGACAAAACTGATTAATGCGGTTGCTAGCATCAGTGGAactgtaaaaaaagaaattccCTCCTCATCTTACAGCATAGCCGCATTTAATGATTATAAAGGTGATGAGGACTTTGACGAATCTGAAGAGTCTGATGAGGATGAAGAAGAGGAACCTCATTCAGGAAAATGGAAACCTCCTCCAAACTACACTGGTGGAAAATGGCGCCCAGCTTCGCCCGATCACGAGGACTGGGATGAGCAAGAGCATACAGGAGGGAAATGGAAACCGATCATAACTGATTCCACCGAAAGGGATGACGACTACGACGCACCACCGCCTGGACATACAAAAGGAAAATGGGTTCCTGGCCATGATAAAACACAAATCATGCAAACAACCATTCAGAGGAAGGGGTCTGTACAGTATTGGTGCGGTCCTTGCAATCGCCGTTTAGGGTCACGAGCTATTTATgaaaaacatttgatgtctAGTTTACACATGAGAAAAGTCCTACCGGAACATGAATTGGAATTCTCCGGACATTTGGAACCAATGCGTTCAGATAAAAGGCCGTCTCGCCCTTCCAGGTTCACCGACGACAGCATCTATGCCAAACCTCAGAAGAAAACGGAAAAGCCCAAAGCCaaaattgcaattaaaatagagaaaaaaaaaagaaagagaaaaCCTACATTTGTTCACTGCTCTGGCTGTAAATCGAGGGTGAGATTGCATTTAATGGGAAAGCATTTGATATCCCATTATCACTTTCGTAAAGCTACTGATATCAAAAGTGAGGCTTACCAGCAATTGATTCTGGACAATATAGACGCAATCGTACACCAATCACCTTTTCAATGCAGCCCATGCAAGTTTTACACGAATTGGTTGTCGACCTTCATGCAGCATTGGTTTTCTGAAGAGCACCAAAACAAAATGGCTCTTTTAGAAGGCCGGTATTGGTGTTCTTTTTGTAAATTCGAGTGTGAATCATCGCAAGAAATGTTACAGCATATGTCGGGGTCTGACCATAGCGAAGTAGTCGCAGTTATAAATAGGTCCATGCCcataattataagaaaaaaaacaatatttagatGTGCCACTTGTGGAGAAGAATTCAAATACAATATGGAGATAAAACGGCATTGTACTAGAACTGGGCACAAATTGGCTTCTACAGCCACAGATGACTATCAGGAGCTGCACAAGTGCCAAAACTGCAAAGCCAAATTCAAATCATCGCTTACCCTGGCAGCTCATTTGAAATCCAAGCATAAGCAAAAAGCATTCTTTTGCTTGGTATGCTCATTATCATTCAACACCTCGAAAGAGGCGAAGCACCACCGCTACACCTCTGAACATCGAATAAGGAAGAAAGAAATCTTACAAGACAAAGGAATGCCTGTTAAAAATTTGAGCAAGAAATGTTCATATTGCACTGAGGAAGTGATCTTAAAGAGCATTATAGAGTTAAAAGAGCATATGCGAACAGTGCAtcctgaaattaaaaaaagATGTCCCAAATGCGGAATGTCATTCACTCTGTTCCAAGAAGTTAGCTATCACGTGAAAAGCAACGCTTGTCAATTCAGAAGCACGCACCCAGGGGACTCCGCTATTATCTGGAACTGCAGCAAATGTCTCTTCAACACAGACTCACAGGCCGAATGCTACTTCCACGAAGTCTTGCACACCAACGCCACGAAAGAATATAGGAAATTTGGTGATAAGGACACGTTAATAGAGAAGTATCGATGCCCTCTTTGCCCCAAGAGTTTCATAAAGAGATCTCTTCGTCAGCATTTGAGGCTGCATACCTTCGAAAGGCCGTTTGTGTGCTCTACATGCGGCGCTAATTTCACAACGCAATCCAGCCTTGCAAATCACTTTAAAAACTGCCACAGCCCACGTATGTTGAATGCGAGTCCGCCGAAAAAGATGGTAGTTCCTGTCCAGCATGCATTCGACGAAGCTTGGAAATGCAGTAAGTGCTCGAAGTCCTTCTCCAACCGGAGCGCGCTGAGCCGGCACGGCTGCGAGGGGCGCAGCTGCCCCCACGCCGACTGCGCGTACGTCGGCGCCACTCCCGCGCATCTAGCCAGACACAGGAATACTCACGGTGAAAAAATAAAGAACCATGAATGTACTTTGTGTTCGTTCAAGACAAACCAGGCGAGTCACATGAAGCGACACATGCGTTGTCACATTGGAGCGAAGCCCTATGGTTGTCCACATTGTGACTTTACTTGTAGTAGTCTGGAGAACCTGCGTAAGCACGTGCTTAGCAGCGGCAGACACCCCGGTAAGCACCTGTACCACTGCAAGTTGTGCACCTACCCCACCAACACGGCAACGGACTTACGAGCACACCTTACCAGCGCACACGCCGACCAATACGACTCGAAGGCCGCAATACAAGCCGTCAAAGTTATTTTGATGAAAGATAATAAGTGA
- Protein Sequence
- MLSPRDDDDDDSHLCIKCNATVVGLDNYVKHRKQRCGKIAKPDTSKADISSIDTLDPTYSLGADVFFQSLELQSSVKKTSLSRLTPPIPITKAVLDTKNTMVEASSSRDLPRMSPLETNLREEDWIGGHSLRIGGNEDNQTKLINAVASISGTVKKEIPSSSYSIAAFNDYKGDEDFDESEESDEDEEEEPHSGKWKPPPNYTGGKWRPASPDHEDWDEQEHTGGKWKPIITDSTERDDDYDAPPPGHTKGKWVPGHDKTQIMQTTIQRKGSVQYWCGPCNRRLGSRAIYEKHLMSSLHMRKVLPEHELEFSGHLEPMRSDKRPSRPSRFTDDSIYAKPQKKTEKPKAKIAIKIEKKKRKRKPTFVHCSGCKSRVRLHLMGKHLISHYHFRKATDIKSEAYQQLILDNIDAIVHQSPFQCSPCKFYTNWLSTFMQHWFSEEHQNKMALLEGRYWCSFCKFECESSQEMLQHMSGSDHSEVVAVINRSMPIIIRKKTIFRCATCGEEFKYNMEIKRHCTRTGHKLASTATDDYQELHKCQNCKAKFKSSLTLAAHLKSKHKQKAFFCLVCSLSFNTSKEAKHHRYTSEHRIRKKEILQDKGMPVKNLSKKCSYCTEEVILKSIIELKEHMRTVHPEIKKRCPKCGMSFTLFQEVSYHVKSNACQFRSTHPGDSAIIWNCSKCLFNTDSQAECYFHEVLHTNATKEYRKFGDKDTLIEKYRCPLCPKSFIKRSLRQHLRLHTFERPFVCSTCGANFTTQSSLANHFKNCHSPRMLNASPPKKMVVPVQHAFDEAWKCSKCSKSFSNRSALSRHGCEGRSCPHADCAYVGATPAHLARHRNTHGEKIKNHECTLCSFKTNQASHMKRHMRCHIGAKPYGCPHCDFTCSSLENLRKHVLSSGRHPGKHLYHCKLCTYPTNTATDLRAHLTSAHADQYDSKAAIQAVKVILMKDNK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00681962; iTF_00683792;
- 90% Identity
- iTF_00681962; iTF_00683792;
- 80% Identity
- -