Basic Information

Insect: Eudonia lacustrata
Gene Symbol: zfh1
Assembly: GCA_947562085.1
Location: OX387315.1:25850235-25860697[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.017 2.1 9.8 0.2 1 23 74 96 74 96 0.94

2 8 4.3e-06 0.00055 21.1 2.8 1 23 107 129 107 129 0.98

3 8 1.3e-06 0.00017 22.7 6.2 1 23 138 160 138 160 0.99

4 8 9.3e-05 0.012 16.9 1.0 1 21 166 186 166 187 0.95

5 8 0.00048 0.063 14.6 0.9 1 21 451 471 451 472 0.93

6 8 6.6e-06 0.00086 20.5 1.1 1 23 768 790 768 790 0.94

7 8 3.3e-06 0.00042 21.5 6.8 1 23 796 818 796 818 0.99

8 8 0.01 1.3 10.4 5.0 1 21 824 844 824 845 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.017	2.1	9.8	0.2	1	23	74	96	74	96	0.94
2	8	4.3e-06	0.00055	21.1	2.8	1	23	107	129	107	129	0.98
3	8	1.3e-06	0.00017	22.7	6.2	1	23	138	160	138	160	0.99
4	8	9.3e-05	0.012	16.9	1.0	1	21	166	186	166	187	0.95
5	8	0.00048	0.063	14.6	0.9	1	21	451	471	451	472	0.93
6	8	6.6e-06	0.00086	20.5	1.1	1	23	768	790	768	790	0.94
7	8	3.3e-06	0.00042	21.5	6.8	1	23	796	818	796	818	0.99
8	8	0.01	1.3	10.4	5.0	1	21	824	844	824	845	0.96

Sequence Information

Coding Sequence: ATGAAAGTGCACAGCTCGCTTATGGGAGTTGGCGGTTGGTACGAAAGCTTGGCGGCCGGTTGGCTCGCGGACATGCGGAGTAAGCAGGTGCCCACGTCCACCACCTCGGCCAGGCGGCTCGCGGCCTTAATCCGTCCGCTGGCGGGCGGGGGGGCGGAGGGCAAGCCGCCCGAGGAGGAGGAGGAGCGCAGCGGGTCGCCGCTGGGTCCCGGCGGGCCCTTCGCCTGCAGCCAGTGCCGTGGCGCCTACCCCACGCGCGACCAGCTGGAGCGCCACGAGACGCTGCACTCGCCCAGCACACAGGTGGATACACTCAGATATTCATGTAAGATTTGCCACAAGAGCTTCGCGAACGTGTACCGCCTGCAGCGACACATGATCAGCCACGATGAGAGCGCGCTGTTGCGCAAGTTCAAGTGCAACGACTGCGACAAGGCGTTCAAATTCAAGCACCATCTGAAGGAGCACCTGCGCATCCACAGCGGGGAGAAGCCCTTCGAGTGCGCCAACTGTGGCAAGAAATTCTCCCACTCCGGCTCCTACTCCAGCCACATGACCTCCAAAAAGTGTCTTGTGATGAACCTCAAAATGGGAAGAATCAAGCCAAACAACCCTGCTTTAAACCCTGAACGAAGTCCATCTAGGAAACGGGCTAATGCGATGGTAACGTCACAGTTAAACAACAACATCGCACCTAACGGAAATTCGTTCCTTCCGATTCTGCCTAAATACAACGAAGCCGCAGCTGCTTTCTTCGCGAACATGTCTTCGCAAGAAAGCAACTTTCATCGGCAGCACATGACACAACCCGGAATGAGCCCCTTCTACATGCCACCGGGAATGCCAATGAGCCCAGCGGGTGGGATTGCGCCTTACAGTTTCCCAGCTTCGCTTAGCCAACTGTTTGAGCAACTAGCTTCATCGCAGTATCAACAAAGAAAAATGGAGCCACTACCTAGTCCAAAGATGACTAGCCCATCTCCTGACGACCCTGAAGACCTAATAGAAGAAGTCACAGAAGAAGACGATAAGCGTTCGGAGGGAAGTGCAGAACTTGTCATGGACATTGAGGAAGATGAAGGAGCACCTATTAAAAAAGAGCAAGAAGATCGTGAACATGACGTAAAGTCACCCCGTAATTACGAATCCGTCCCCTTAAATAACAACGACCAAATGCATAGTAATCATTCTGGTTTCAACACAATAATAGAATCCGTGAATGCTTCTGTTACAAAACACTTTTTTAGAGCAAATAGTGAAAAGCTATCGCCAGTGTCGGGTAACGTGGGCTCCAGAATAGATTCACCTCCAACTTCGCACATTATCGTCAAAGAAGAACCTGTAGACGCACATAGGTGCTTGAAATGTAATACCACATTTAATAATAGCTCCGATTTATTAGAACATGAAAAAGTGGTCTGTGGAAATTTATTCAGAAAACATGAAGGACTGGCAGCTCAAGTGGCCGAGACTGTAGCACTAAATAGGTTTGAAGCCGAAATGCGAGCTTCAATTCAAAGCGGCGTCAGTGCCAGTGAAGACGAAGACTTTGCAAGAGAGGAACGTGATGACAAAATGTCTCTTCATGATAACGACAGAAAAATAAGAGTACGAACTGCGCTTAGCGAGGAACAGCAAGCTATATTGAAGGAACACTATTCCATCAACCCGAGGCCTAATCGAGAAGAATTTAAAAGAATTGCACTAAAGATAGGGCTTGACAATAGAGTCGTACAAGTTTGGTTCCAAAATAATAGAGCGCGCGTACGGAGAATGACACAAACGCTAACAATGTCTGACCAGCCGCTCGACTTGTCGACCAAGAAATCGAACCAGTCTACGACGCCGAGCCCGACTCCTTCGCCGTCGTGCAGCATTTCAGTCACACATTCCGATTCCGAAGAGGCGGTAAACCTCAGCCAGAAGTCATCGCGCAGCCCCACGCCGCATCGCCCCAACTACAACAACACGTACCCACATTCCAATTGCTCATCATCTTCTTTCACGGATTTTCGACTATCTCCCTCACCAGGGGAACCTATTAATGGACAAAAGCGATTATTACCTCAAAAAATGCTCATGAACAATTTGATGCCAATGGAACGAATACTTCAGCACAATGACGTAGCCAATATGAGGTCACCGATTCTCAAAATGGAGATGAACCCGGACCACCGACAGGCGTCGAGCCCCTCGTACGAGCGGCTCCCGTGGAGGGAATCGCAAAACGAATTCGATGACGATGCGCCAGTACTTAAGAAGAGCAAACTGAAGCAAGAATTCAAAGAAGGCGAAGATCATTTCGTCTGCAACCTTTGCGATAAAACTTTCGTCAAGCAAAGTTCTCTAGCTAGACATAAATATGAACATTCAGGCCAGCGCCCGTACAAGTGCGAGGTGTGCCCCAAGGCGTTCAAGCACAAGCACCATCTGACGGAGCACCAGCGGCTGCACACCGGCGAGAAGCCCTTCCAGTGTTTCAAGTGCCTAAAGAAGTTCTCCCACTCCGGCTCCTACAGCCAGCACATGAACCATAGATTCGCCATCTGCAAGCCGTATCGTACCTAA
Protein Sequence: MKVHSSLMGVGGWYESLAAGWLADMRSKQVPTSTTSARRLAALIRPLAGGGAEGKPPEEEEERSGSPLGPGGPFACSQCRGAYPTRDQLERHETLHSPSTQVDTLRYSCKICHKSFANVYRLQRHMISHDESALLRKFKCNDCDKAFKFKHHLKEHLRIHSGEKPFECANCGKKFSHSGSYSSHMTSKKCLVMNLKMGRIKPNNPALNPERSPSRKRANAMVTSQLNNNIAPNGNSFLPILPKYNEAAAAFFANMSSQESNFHRQHMTQPGMSPFYMPPGMPMSPAGGIAPYSFPASLSQLFEQLASSQYQQRKMEPLPSPKMTSPSPDDPEDLIEEVTEEDDKRSEGSAELVMDIEEDEGAPIKKEQEDREHDVKSPRNYESVPLNNNDQMHSNHSGFNTIIESVNASVTKHFFRANSEKLSPVSGNVGSRIDSPPTSHIIVKEEPVDAHRCLKCNTTFNNSSDLLEHEKVVCGNLFRKHEGLAAQVAETVALNRFEAEMRASIQSGVSASEDEDFAREERDDKMSLHDNDRKIRVRTALSEEQQAILKEHYSINPRPNREEFKRIALKIGLDNRVVQVWFQNNRARVRRMTQTLTMSDQPLDLSTKKSNQSTTPSPTPSPSCSISVTHSDSEEAVNLSQKSSRSPTPHRPNYNNTYPHSNCSSSSFTDFRLSPSPGEPINGQKRLLPQKMLMNNLMPMERILQHNDVANMRSPILKMEMNPDHRQASSPSYERLPWRESQNEFDDDAPVLKKSKLKQEFKEGEDHFVCNLCDKTFVKQSSLARHKYEHSGQRPYKCEVCPKAFKHKHHLTEHQRLHTGEKPFQCFKCLKKFSHSGSYSQHMNHRFAICKPYRT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00281695;
90% Identity: iTF_01334651;
80% Identity: iTF_00681547;