Basic Information

Gene Symbol
-
Assembly
GCA_963930755.1
Location
OZ005736.1:281045324-281052360[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 0.0054 0.61 12.2 4.5 1 23 19 42 19 42 0.96
2 24 0.00012 0.014 17.4 1.9 1 23 55 77 55 77 0.96
3 24 2.8e-05 0.0032 19.4 2.1 3 23 82 102 81 102 0.98
4 24 1.5e-06 0.00017 23.4 2.3 1 23 108 130 108 130 0.98
5 24 1.3e-05 0.0014 20.5 0.7 3 23 138 158 136 158 0.97
6 24 0.016 1.9 10.7 0.9 2 23 165 186 165 186 0.93
7 24 0.00031 0.035 16.1 0.4 1 23 192 214 192 214 0.97
8 24 1e-05 0.0012 20.8 0.2 1 23 220 242 220 242 0.98
9 24 0.0041 0.47 12.6 5.1 1 23 275 298 275 298 0.97
10 24 2.3e-06 0.00026 22.8 1.8 1 23 311 333 311 333 0.98
11 24 1.6e-06 0.00018 23.4 0.4 1 23 336 358 336 358 0.97
12 24 0.00019 0.022 16.8 4.3 1 23 364 386 364 386 0.98
13 24 7.5e-05 0.0085 18.1 0.7 3 23 394 414 392 414 0.97
14 24 0.016 1.9 10.7 0.9 2 23 421 442 421 442 0.93
15 24 5.9e-05 0.0067 18.4 1.4 1 23 448 470 448 470 0.98
16 24 5.5e-06 0.00062 21.7 0.4 1 23 476 498 476 498 0.98
17 24 0.016 1.8 10.7 5.4 1 23 531 554 531 554 0.97
18 24 1.6e-05 0.0018 20.2 0.5 1 23 567 589 567 589 0.98
19 24 3.8e-06 0.00044 22.1 0.2 2 23 593 614 592 614 0.96
20 24 0.00019 0.022 16.8 4.3 1 23 620 642 620 642 0.98
21 24 7.5e-05 0.0085 18.1 0.7 3 23 650 670 648 670 0.97
22 24 0.016 1.9 10.7 0.9 2 23 677 698 677 698 0.93
23 24 5.9e-05 0.0067 18.4 1.4 1 23 704 726 704 726 0.98
24 24 5.5e-06 0.00062 21.7 0.4 1 23 732 754 732 754 0.98

Sequence Information

Coding Sequence
ATGCATTTTTTATTCCAGACCGAGGTCAAAAAGAGTTCCAAGAAGAAAAATGCTCATAGCTGCGAAATTTGCCACAATTCATATAGCAATACACAAGGTTTGCAAAGACACCGGAAAAAGGTCCACAATATCAATATATCGCTGAGGAAAGTATATTATAGACACAAATGCGATGAGTGTGATCAGGCATTCAGAACTCAACGAGATCTTCGCGGACACAGAGTAAAACACACCGGTATCCTGTGTGATATTTGCGGCAAATCCTTCACTCACGTCGAGAATATGAAACGTCATCGTATTCGTCATACTGGCATCAAGGAACATAAGTGTAAAGAATGTCCCAAGGAATTTTATACGAATAAGGAGCTACAAGCTCATATGATGTCCCATACGGGTATTTTGCCTGTGATTTGTGAAATTTGTGGTAAACGTTGTCGTGATCGTGGCGTTCTGACGGCCCACATGCGCCGACACACGGGCGAAAGACCCGCCAAATGCGAGGTGTGCGAAAAAAGTTTCTTTTCCATTCATGATTTGAACCTACATTCCGTCATACATACGAATGAGCGACCATTTCCCTGTGAGATATGTGGTTCACGCTTCCAACGCAAGAAGGCTTTACGTATTCATAAACTTATACATTCCGGTGATCGCAAACACGTTTGCGCTATTTGTGGCAAAGGATTTACTCTAGCAGGAGGTTTGAAAACGCACCTTCGCACACATAATGATGCCAAGGGAGACTTAAAGGGcgaagcagcagcagcaccagtgTATGTGCCGGAGACCAAGCAGAATAAGGGTTCCAAGAAGAATAATGTTCATCGCTGTGACATTTGCCACATTTCATATAACAAAAGACTGGATTTGCAAAGACATCGGAAAAAGGACCACAATATCAATACAGCGTCGAGGAAAACATATCACAGATACAAATGCGATGAGTGTGATAAAACCTTTAGAACTGAATACAACCTAAATGGACACAAGTTAAAGCATGCGGGTTTTGCGTGTGATATATGCGGCAAAACTTTTACTCAGGCAGGCAATATGAGAACCCATAGAATACGTCATACTGGTATTAAGGAACACAAGTGCAAAGAATGTCCCAAGGAATTTTATACGGAAAAGGAACTACATATGCATATGCTGTCTCATACGGGAAAGATGCCTGTGATCTGTGAAATTTGCGGCAAACGTTGTCGTGAACGTGGCGTTCTGACGGCCCACATGCGCCGACACACGGGCGAAAGACCCGCCAAATGCGAGGTGTGCGAAAAAAGTTTCTTCTCCATTCACGATTTGAACCTACATTCCGTCATACATTCGAATGAGCGACCATTTTCCTGTGATGTATGTGGTTCCAGCTTTCAACGCAAGAAGTCTTTGCGTATTCATAAACGTATACATTCCGACGAACGCAAACACGTGTGTACAATTTGTGGCAAAGGATTTACAATAGCAGGAGGTTTGAAAACGCACCTTCGCACACATGCTGACGCCAAGGCAGATTTGAACAGCGAGGCATCAGCAACACCAGTGTATGTGCCTCCGaccaAGAAGAATAAGGGCTCCAAAAAGAATAATGCTCATCGCTGTGACATTTGCCACAATTCATATAGCAAAACTCAGGGTTTGCAAAGACACCGGAAAAAGGTCCACAATATCGATATATCGCTGAGGAAAGCATATTACAAATACAAATGCGACGAGTGTGATCAAGCCTTTAGAACTCCTCGAGATCTTCAGGGACACAAGCTAAAGCATACGggcatagtgtgtgatatttGCGGCCAATCTTTTACTCAGGCAGGCAATATGAGACGCCATAGAATACGTCATACTGGTATTAAGGAACATAAGTGCAAAGAATGTCCCAAGGAATTTTATACGGAAAAGGAACTACATATGCATATGCTGTCTCATACGGGAAAGATGCCTGTGATCTGTGAAATTTGCGGCAAACGTTGTCGTGAACGTGGCGTTCTGACGGCCCACATGCGCCGACACACGGGCGAAAGACCCGCCAAATGCGAGGTGTGCGAAAAAAGTTTCTTCTCCATTCACGATTTGAACCTACATTCCGTCATACATTCGAATGAGCGACCATTTTCCTGTGATGTATGTGGTTCCAGCTTTCAACGCAAGAAGTCTTTGCGTATTCATAAACGTATACATTCCGACGAACGCAAACACGTGTGTACAATTTGTGGCAAAGGATTTACAATAGCAGGAGGTTTGAAAACGCACCTTCGCACACATGCTGACGCCAAGGCAGATTTGAACAGCGAGGCATCAGCAACACCAGTGTATGTGCCTCCGGTGTTTATAGGAAGCCCACTTGTAAATATAATTGCTGGTAATGATAGTCTAAGTagtcaacaaatttaa
Protein Sequence
MHFLFQTEVKKSSKKKNAHSCEICHNSYSNTQGLQRHRKKVHNINISLRKVYYRHKCDECDQAFRTQRDLRGHRVKHTGILCDICGKSFTHVENMKRHRIRHTGIKEHKCKECPKEFYTNKELQAHMMSHTGILPVICEICGKRCRDRGVLTAHMRRHTGERPAKCEVCEKSFFSIHDLNLHSVIHTNERPFPCEICGSRFQRKKALRIHKLIHSGDRKHVCAICGKGFTLAGGLKTHLRTHNDAKGDLKGEAAAAPVYVPETKQNKGSKKNNVHRCDICHISYNKRLDLQRHRKKDHNINTASRKTYHRYKCDECDKTFRTEYNLNGHKLKHAGFACDICGKTFTQAGNMRTHRIRHTGIKEHKCKECPKEFYTEKELHMHMLSHTGKMPVICEICGKRCRERGVLTAHMRRHTGERPAKCEVCEKSFFSIHDLNLHSVIHSNERPFSCDVCGSSFQRKKSLRIHKRIHSDERKHVCTICGKGFTIAGGLKTHLRTHADAKADLNSEASATPVYVPPTKKNKGSKKNNAHRCDICHNSYSKTQGLQRHRKKVHNIDISLRKAYYKYKCDECDQAFRTPRDLQGHKLKHTGIVCDICGQSFTQAGNMRRHRIRHTGIKEHKCKECPKEFYTEKELHMHMLSHTGKMPVICEICGKRCRERGVLTAHMRRHTGERPAKCEVCEKSFFSIHDLNLHSVIHSNERPFSCDVCGSSFQRKKSLRIHKRIHSDERKHVCTICGKGFTIAGGLKTHLRTHADAKADLNSEASATPVYVPPVFIGSPLVNIIAGNDSLSSQQI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-