Basic Information

Gene Symbol
ECU06_1150
Assembly
GCA_037177015.1
Location
JBAGKK010164246.1:7009-10422[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.00096 0.33 13.7 0.1 2 23 336 357 335 357 0.96
2 15 3.3e-07 0.00012 24.6 2.3 1 23 360 382 360 382 0.99
3 15 9.5e-07 0.00033 23.1 1.0 1 23 388 411 388 411 0.96
4 15 0.0027 0.93 12.3 0.3 1 23 417 439 417 439 0.98
5 15 0.0011 0.39 13.4 2.7 1 23 445 467 445 467 0.96
6 15 0.00036 0.12 15.0 3.0 1 23 473 495 473 495 0.97
7 15 3.1e-05 0.011 18.4 0.7 1 23 501 523 501 523 0.97
8 15 0.013 4.4 10.2 5.2 1 20 597 616 597 618 0.95
9 15 0.0011 0.36 13.5 2.4 1 23 708 730 708 730 0.98
10 15 1.3e-05 0.0045 19.5 1.6 1 23 736 759 736 759 0.97
11 15 2.8e-05 0.0097 18.5 0.1 1 23 765 787 765 787 0.98
12 15 1.4e-07 4.9e-05 25.7 0.6 1 23 793 815 793 815 0.99
13 15 4.8e-05 0.016 17.8 1.5 1 23 821 843 821 843 0.98
14 15 0.00014 0.048 16.3 2.5 1 23 849 871 849 871 0.97
15 15 9.5e-05 0.033 16.8 4.1 2 23 878 900 877 900 0.96

Sequence Information

Coding Sequence
ATGGAGTCTCAAAATTCAGTGATATTAACCTCGTGTGAAGAAGAGGCTGATCCGCTTTCAATGGACATCGTGAAAGAAATAGTTGAGAAGGCAGATGATGCTGAGATCGAAGAAGGAGAATATTTACTAGTATCTAATGTCCAGGAAGACCTAGAGGATGGAGAGATGCAAGTCATCGCCGAAGAAAATGAAACTCCATCGCTGTCTCAGATGTGTAGAACTTGTGCCAACGCCAATGGCCATCTCGTACCAATTTTTACAGGGGAAGGACTTGAACAAGATTTATGTAGCAAGATACAAAAGCACCTACCCATTAAAGTTACGAAAGATGACTCTTTACCTCAACAACTATGTTACCACTGTGCCGCTACAATCTTAGCATGGAGCGAACTTTCTGAAGGTTGTTTATACGCTCAAAATCAGCTTTTGCGACTACAAGAACAAGCAGAGCAACGAAagTCTCTAGCCTATCAACAAcaagaagaagagaaagatgATCAGATTGAAGAAAACACGATCGGTGATGGAAAATTCGTTAATAGAGAATTGCCGCAGGAAGAGCAACGGAAGCATGGTCATATGAAGAATGCGCAAGTGAAAAACGAAGAAGTCTCAGAGTCAGAAAGAAAGGGAAAGCAAACAAACCCGCAAAAATTCAAACAACGAGCTCGAAAACTCAATCGACGTTCGCGATTTGAAATTACGCGACAGAGCCGAATGTCCGGAGTCAAGTTTCGACTATTTTCCAGGTCCAGTAGTGTCCAGCCGACATTTAAAGTATTCCTTGAAACGCAAAATATGTTTTGGAGGACCTTGAAACGGAGATACGACGTGACGGATAAAATATCGGGCAACTCGTCACTACATCCTGATTCGGTTTTGGCTCCAGCATCAGTTGATGACTTGAAAGAAGAGTCGTTAAAGCAGGAACAAAATCAACACtatgaagattttcaaaacatttcagaaGTTACTGCCAACAGCGACAGCGAAGAGCTCCATTGGAAGTGTAAAATCTGCGCCCGTGAATTTGACTCTGCCgctgaattgaaaattcactCTAAAGTTCATGAATCTTACCAGTGTCACGAGTGCGGCAGAGTCTTCAAACTGAAGGACTCGCTTTTACGTCACACTCGAATTCACAAAGACGAGCGTCCTTTTACGTGTCACGTGTGCGGGAAACAATTTCGAGACTCCGGTGGTCTCTCCCGCCACCTAAGAGATGTGCatgctaaattaaaaaacttcccCTGCGATCTTTGTGGAAGCAGCTTCGCGTCAAAAGCGACACGAGACGATCATCGCCGAACGCACACTGGTGAACGACCTTACGTTTGCGATTGCTGCGGGAAAACATTTAAATCTAAGGCTTCTCTCTACATTCACAGTAAGCTACACACCAACGAATTTCCTCATCCGTGTTCCTACTGCACCAAAAAGTTCCGTCGCAGACAGGAGATGTTGGCCCATGTGACAACTCACACTGGTGAAAAAAACTACGCGTGTGATATGTGTTTGAAGCGTTTCCGGGTGAAATCAGAGCTTATGCGACACCGATTAATTCACTCGGATGACAAACCATTTGCCTGCACCAAATGTGGTCTCGCGTGCGGCGCGCCGAGGACCTCGTCTTTCGCGACGTACCTTTCCAAGCGTGAGGTCAATGTTCTCCGGCCTAGGATTAACCAGGATAGAGTAAAATCAACCAATCAATCCCAGGTGTTGATAAAAACCGAGGAAGACTTGGTTGAAGACTCATCTACAATTTCCAAGAATTCTCAGCAATACACCTGCGAATACTGTCGGAATTCTTTCCACAAGAAATCTCACTTAAAGTATCATCTGACGAGCTGTTCCTCAAGTGTGAGCCAACAAAACttcagaataaaagaagaaaaacaaggTGAGGAAAATTGCCAGACTTCCGAACGCCACCAAAGAAAACGCCAAAAATCCTATCCATGTATGCACTGCAATTACGATgccaagaagaagaagattctTGATCTGCACACACAAGAGGCTCATCCAGAATTGATAAGTTCCAATAATAAGACACGCAGCATCGACAAGCAAGCGATTGATGAAGCGAAAATGGAGGTTGATGGTAAGGTATACTATCATTGTACCGAGTGTGGGAAAAATCTCTACTCTCCCTATACATTTTCTTGGCACAAGCGAATCCACACTGGTGAAAGGCCCTTCACTTGTCATCTCTGTGGAAAACAGTTTCGGGTCAGTCAAGGCCTAGCTCGTCACTTGCGCGAAACTCACGctggaataaaaaagtttccttGCGACATATGCGGGCGAATGTTCGCCGGGAAGCGAAATGTCGAAGATCATCGGCGAATTCACACTGGTGAGCGACCTTACGTCTGCAACATTTGTGGCAAAGCCTTCAAGCAAAAAGCCTCACTCTTTGTTCATAATCGCACTCACTCGGATTTATTTCCCTTCAAATGTTCCTATTGCAATCAAGGCTTTCGGACTAAAACTCCGCTGATGGTTCACATCACGAAACACACTGGCGAGAAGCCCTACGCGTGCGATATTTGCAATCGACACTTTCGCATCAAGTTTGAATTGAAGCGACATCGACTTATTCATTTTGACGAAAAGCCCTGGCGATGCACAGATTGCAACCAGTGCTTTAGACAGAAAAGATATCTCGTTAATCACAGGAAAGTGAATCACGACAATGCGGAAATTGCCAAACAGTGA
Protein Sequence
MESQNSVILTSCEEEADPLSMDIVKEIVEKADDAEIEEGEYLLVSNVQEDLEDGEMQVIAEENETPSLSQMCRTCANANGHLVPIFTGEGLEQDLCSKIQKHLPIKVTKDDSLPQQLCYHCAATILAWSELSEGCLYAQNQLLRLQEQAEQRKSLAYQQQEEEKDDQIEENTIGDGKFVNRELPQEEQRKHGHMKNAQVKNEEVSESERKGKQTNPQKFKQRARKLNRRSRFEITRQSRMSGVKFRLFSRSSSVQPTFKVFLETQNMFWRTLKRRYDVTDKISGNSSLHPDSVLAPASVDDLKEESLKQEQNQHYEDFQNISEVTANSDSEELHWKCKICAREFDSAAELKIHSKVHESYQCHECGRVFKLKDSLLRHTRIHKDERPFTCHVCGKQFRDSGGLSRHLRDVHAKLKNFPCDLCGSSFASKATRDDHRRTHTGERPYVCDCCGKTFKSKASLYIHSKLHTNEFPHPCSYCTKKFRRRQEMLAHVTTHTGEKNYACDMCLKRFRVKSELMRHRLIHSDDKPFACTKCGLACGAPRTSSFATYLSKREVNVLRPRINQDRVKSTNQSQVLIKTEEDLVEDSSTISKNSQQYTCEYCRNSFHKKSHLKYHLTSCSSSVSQQNFRIKEEKQGEENCQTSERHQRKRQKSYPCMHCNYDAKKKKILDLHTQEAHPELISSNNKTRSIDKQAIDEAKMEVDGKVYYHCTECGKNLYSPYTFSWHKRIHTGERPFTCHLCGKQFRVSQGLARHLRETHAGIKKFPCDICGRMFAGKRNVEDHRRIHTGERPYVCNICGKAFKQKASLFVHNRTHSDLFPFKCSYCNQGFRTKTPLMVHITKHTGEKPYACDICNRHFRIKFELKRHRLIHFDEKPWRCTDCNQCFRQKRYLVNHRKVNHDNAEIAKQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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