Espl024864.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Eubasilissa splendida
Gene Symbol
-
Assembly
GCA_031772225.1
Location
CM062863.1:9060666-9072685[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 0.00065 0.054 15.0 5.1 1 23 301 323 301 323 0.97
2 25 0.11 9.1 8.0 2.1 1 23 329 351 329 351 0.98
3 25 0.01 0.83 11.2 0.8 1 23 359 381 359 381 0.97
4 25 0.5 42 5.9 1.8 1 23 387 409 387 409 0.96
5 25 0.35 29 6.4 2.5 1 23 415 439 415 439 0.94
6 25 0.00043 0.035 15.6 2.8 2 23 446 467 445 467 0.97
7 25 0.19 15 7.3 0.2 1 23 473 495 473 495 0.97
8 25 0.0043 0.35 12.4 4.7 1 23 501 523 501 523 0.96
9 25 0.011 0.87 11.2 2.5 1 23 529 551 529 551 0.96
10 25 0.0014 0.11 14.0 3.9 1 23 557 579 557 579 0.98
11 25 0.48 40 6.0 7.5 1 23 585 607 585 607 0.97
12 25 1.9 1.5e+02 4.1 1.8 1 23 613 635 613 635 0.97
13 25 0.0011 0.088 14.3 2.5 1 23 641 663 641 663 0.97
14 25 0.00063 0.052 15.0 3.0 1 23 669 691 669 691 0.97
15 25 0.0009 0.074 14.5 2.9 2 23 698 719 697 719 0.96
16 25 3.1 2.5e+02 3.4 0.0 1 23 725 747 725 747 0.90
17 25 0.00041 0.034 15.6 1.1 1 23 753 775 753 775 0.96
18 25 0.025 2 10.0 4.9 1 23 781 803 781 803 0.95
19 25 0.014 1.2 10.8 0.4 1 23 809 831 809 831 0.98
20 25 0.0053 0.44 12.1 0.3 1 23 837 859 837 859 0.98
21 25 0.00017 0.014 16.8 0.5 1 23 865 887 865 887 0.99
22 25 0.37 30 6.3 1.9 1 23 893 915 893 915 0.97
23 25 0.17 14 7.4 3.5 1 23 921 943 921 943 0.97
24 25 2.9 2.4e+02 3.5 4.0 2 23 950 971 949 971 0.95
25 25 0.0065 0.53 11.8 3.0 2 23 977 998 976 998 0.97

Sequence Information

Coding Sequence
ATGGCTGCCTTGAAAATACATCGGAGGCGAGTCCCCATTCCGACCCGGGCTTCTGTCGCTCTGGAGGACGGCAGACACCTCATCCCGGTAATGTTTAACAAAGAAGGCATAGCGGACAAGCTCGCAATAGAACGGAGAACCAAATGGATCCTCGCTCTGGGCCGGATAGACATATCAGAAGATGATATAAACAATGAGAGAGTTTGCTCTAAACATTTTGTGAGAGgtATACCGAGTGATTTAAATGATGTTACCAATGTAGACTGGATCCCCAGTCAATTTTTAAGTCATGGTTTCAGAAAAACAAATGGTTTTAGACCTCCAAAATATATTGAGAATGAACTGGCACTGAACATGAATCTGATGGAATGCAATCGCGGTGTTTTGCCTGTGGAGTTTATCAAAGAAGAACCTAGAGAAATACCAGTAGATGAAGACAAACCCACAGAACGTAGCAATTCTTATACAATCGATAACGTAGCACTCGACGCAGATAAATACAAAGAAAAGCGATACTTGTATAGAGAATATCAcgaatctaataataaatttgctgAAGTCAAAGTAGAATACTCAGATGAGCCGACGAAAGCCGATGATGACAGCTTAAGTTCTacatttgatgaaaataattctCTAAAATTAGGCTATAACTTCAGCGATGGCGCCATGGATCTCAGTATTGTCAAAAAAGAATGTGAGACTCCGTTCTATGGAATGATGAACCAATTTCTGCAAGTTCAACATAAATTCCCCAATCAAGATGAAGAACCTGGAAACCCATTTGAGAAAGTTGAAAGATTCTCAAAAAAACGTAAGGCAGAAATTAATGATGAAACTGACCCTACATATTCATCGGTAAAGAAACAACGAAtcaaaagagataaaaatacaaaacccCACGAATGCAATCGCTGTAATATGAAATTCAAAATGAAGTCCTATTTAAAACGCCATCAGTTATTACACGATGCTGAGAAAAATTTTGAATGCGATACGTGCGAATTCAAAACAAAGGCACAGCGCTATCTGACGCAACACAAACTAACTCATGTAGATCCTGATCAAAAGCCATACGTTTGTGACATGTGCGGATGTATTCTGAGCTCCGATCGCGCCTTGAAGAAGCATCGTCAAGGGCATACGGGAAACAAGCCCCACGTGTgtgatatttgtgatttttcaaGTCGTTGCGCCGCTTCTCTTAAACTTCATCGCCTAATTCACAGCGGAGAAAAACCATTTGCTTGCACATATAATGGATGCAAGTTCACGTGTAGAGAGGctaaatatttgaagaaacatGAACTCGTACATACAGGAGAAAAACCGATATCATGCGAGGAATGCAGCTACACCTGTCGTACGTCAGCTAGTCTTAAAATTCACCGGCGAAAACATACCGGAGAAAAACCGTTCGTTTGCGAAATCTGCGCTTTTGCTTGTCGGGAGATGGTCGTACTGAAGAAACACATGATCGTGCATACAGGAGAGAAACCTTTCGCATGTACGGAATGTTCCTACGTCTGCAGCCGTCAGACGAGGCTCCGACATCACATGCTGCTTCATACtggagaaaaaccattttcatgttcacagtgctcCTACGCctgccgggattcaaaccagCTCAAACAGCATTCCATCATTCACACAGATCTCAAGCCTTTCACTTGTGATATTTGTGATTATGCGTGCCGCAGAAAAAAGGTCTTAAAAAAGCACAAACTATCGCACGAAGATCAGTCTGcacacaaatgtaaaaaatgcaagTTTAGTTGCGAAGATGAACATGAATTTAAGATGCATATTGATATCCATGAAGCAGAAATGatttacaaatgtatatattgcGAATTTAAAAGCGATGACTCACAAAAATTAGACAAGCACCAGTTGAAGCATAAAGAAGTTAAACCGCATGTCTGCGAGACGTGTGGGTATTCCTGTAAACTCCCTTCAAATATGAGATTACACGTTATGACGCACACCGGAGAACGTCCCTTTGCATGCGACCTTTGTGACTATAGATGCAAACGAGCAAACTCACTAAAGAACCATAGGCTGACGCATTGCATGGAGAAGCGTCTGTCTTGCGCCGAGTGTGGCTGTCCATTCCGAACGCAAACACATCTCGTTGAGCATAAAAGACAACACGATCACGGGCAACCGTTTACGTGTGAAGACTGTTCATTTGTTGCTGAAAGCGCCGCAGAAATCATAGAACACACCTTCATTCACGTGACTGATAAATTATTTGCCTGCGACGAATGCGGACACTCAACCAAAACAGCGTCAGGactaaaaaatcacaaattacaGCACGTTGACGATTTGCCGTATTGCTGTCACATTTGTGAATACAAAGGCAAAACGCGGGCCAATCTCCGGCGCCACAGCTATATACATATTGTGGACAAGAGCTACGTGTGCGATCAGTGCAGTTTTTCTTCCATGTTACCGAGTAAATTAAAAGAGCATCTGCGTGTGCATAcgggtattttaaaatataagtgcAGCGAATGCGATTACGCCTCAAATTTGATGGTCAAGTTAAAACGACACATCTTAATACACACTGGAGAAAGGCCGTACAGCTGTGACCAGTGCCCATACACCGGGAGATCTCCAGATAcgttaaaaattcacaaacgaACACACGCGACAGAAAAACCTTTCTCGTGTGAGCTTTGTCTCTTTTCTACGAGACACATGAAGGATCTGGTGAATCACAGGCTAAttcacactggtgagaaacctTTTTCTTGCGACGAATGTTCATTCAGATGCAGACTGCTCGCAAAGCTGAATAAGCACAAACGTGGCCACGCGAGTAGCAACACTTTGTCTTGCAAAATGTGCGACTTTCAGTGCAGTCTTCATTATGTTCTGAAGGAGCACATGACCGAGCATTTTGGCGAGCCCATGAAATGTGACGCTTGCGATTATTCTTGCAGAACGAGACGTGCGATGAAGCGACACTTATTAACGCATATTGTCACGAATGATCAACCGTTTGGAGATCTGattcgacaaattttagaaaaatctcACAGCTAG
Protein Sequence
MAALKIHRRRVPIPTRASVALEDGRHLIPVMFNKEGIADKLAIERRTKWILALGRIDISEDDINNERVCSKHFVRGIPSDLNDVTNVDWIPSQFLSHGFRKTNGFRPPKYIENELALNMNLMECNRGVLPVEFIKEEPREIPVDEDKPTERSNSYTIDNVALDADKYKEKRYLYREYHESNNKFAEVKVEYSDEPTKADDDSLSSTFDENNSLKLGYNFSDGAMDLSIVKKECETPFYGMMNQFLQVQHKFPNQDEEPGNPFEKVERFSKKRKAEINDETDPTYSSVKKQRIKRDKNTKPHECNRCNMKFKMKSYLKRHQLLHDAEKNFECDTCEFKTKAQRYLTQHKLTHVDPDQKPYVCDMCGCILSSDRALKKHRQGHTGNKPHVCDICDFSSRCAASLKLHRLIHSGEKPFACTYNGCKFTCREAKYLKKHELVHTGEKPISCEECSYTCRTSASLKIHRRKHTGEKPFVCEICAFACREMVVLKKHMIVHTGEKPFACTECSYVCSRQTRLRHHMLLHTGEKPFSCSQCSYACRDSNQLKQHSIIHTDLKPFTCDICDYACRRKKVLKKHKLSHEDQSAHKCKKCKFSCEDEHEFKMHIDIHEAEMIYKCIYCEFKSDDSQKLDKHQLKHKEVKPHVCETCGYSCKLPSNMRLHVMTHTGERPFACDLCDYRCKRANSLKNHRLTHCMEKRLSCAECGCPFRTQTHLVEHKRQHDHGQPFTCEDCSFVAESAAEIIEHTFIHVTDKLFACDECGHSTKTASGLKNHKLQHVDDLPYCCHICEYKGKTRANLRRHSYIHIVDKSYVCDQCSFSSMLPSKLKEHLRVHTGILKYKCSECDYASNLMVKLKRHILIHTGERPYSCDQCPYTGRSPDTLKIHKRTHATEKPFSCELCLFSTRHMKDLVNHRLIHTGEKPFSCDECSFRCRLLAKLNKHKRGHASSNTLSCKMCDFQCSLHYVLKEHMTEHFGEPMKCDACDYSCRTRRAMKRHLLTHIVTNDQPFGDLIRQILEKSHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-