Espl021263.1
Basic Information
- Insect
- Eubasilissa splendida
- Gene Symbol
- ZNF219
- Assembly
- GCA_031772225.1
- Location
- CM062859.1:30432638-30433972[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.26 21 6.8 0.0 2 23 128 149 127 149 0.96 2 11 5.3e-05 0.0044 18.4 0.1 1 23 155 178 155 178 0.95 3 11 1.9e-05 0.0016 19.8 1.7 1 23 189 211 189 211 0.98 4 11 2.9e-06 0.00024 22.4 1.0 3 23 219 239 218 239 0.99 5 11 1.8e-06 0.00015 23.0 0.3 1 23 245 269 245 269 0.98 6 11 6.4e-06 0.00053 21.3 0.3 1 23 275 297 275 297 0.98 7 11 2.2e-05 0.0018 19.6 0.2 2 23 304 326 303 326 0.96 8 11 1.9 1.6e+02 4.1 1.8 2 23 332 350 331 350 0.85 9 11 0.0002 0.016 16.6 1.1 1 23 356 378 356 378 0.97 10 11 2.1 1.7e+02 3.9 2.5 1 23 384 409 384 409 0.90 11 11 0.00029 0.024 16.1 3.0 1 23 415 437 415 438 0.95
Sequence Information
- Coding Sequence
- ATGACATCAATTTTCGAATATgaagataattataaatattttgaaaaaattcagcATTGCGCTAACATAAACATAGCCGAGCTCGACGGCTACCCATCTCTAATTTGTGGTGATTGTCGAGCGGAATTATCTATAGCTTACGTATTTGTTACTAAGTGTCAGAATTCCGATAAATATCTGCGCGATTCTAAGTTGGAAGTTGAGGTTAAGGTCGAGCTGGACCTCTCCGAAGATGTCTCCGACCGCAGTTGCGACCTGCCTGATATTGCTTCGGACGAAATATTTGTCAAGCGGGAAAACACGAGCGCACAAGCCAGGAAGTACAAGACGAATAGTAAAGTTCGGAAAAGAGTGAAAGTTAAGAAAGAAGCCAGCGATCTGCAGTGCGCCACCTGCGGCCTGTTGGTGGCCAGCAGAGCAGCTATGATCATTCACGTGCGGCGGCACACCGGGGAGCGACCTTACCAGTGCGGGCAGTGCGGCGCGCGTTTCTCGCAGGCCGGCACGCTCAAAGTGCATGCAGCGCGCCGGCACGCGCCGCCCGCTGGGCCGCGCCCGCGTCCCTTTCCTTGCTCACACTGCGGCGGCCGCTTCTACAGTCGGCGGGACTTGACAGTGCACGTGCGCACACACACGGGCGAGCTGCCACACGGCTGCGCTCAGTGCGGGCGCCGTTTTTCCCAGCTCAGCTCGCTCATCCGCCACAAGCGCACGCACACTGGCGAGCGGCCCTACCGCTGTCCTGAGCCTCGCTGCGGGAAGGCATTCACGGACCGCTCCATGTTGCGACAACATCGCTCTGTACATAGTGAGGAGAAGCGCTATCGCTGCGCTGTATGCGGTAAGGCCGTCAAGTCGCAGAATACTCTCAATAAGCACATGAGTCTGCACCGTGAGGCTAAGCCCGTGATGTGTGAGCGCTGTGGGGCTGCCTTCTCTACCAAGGGCAATTTGAGCTCGCACGTACGTCGTCAGCATGGCGCACGCTCGGGTCAATGCAGCATGTGCGGGCGCGAGGTACCCGACTTGCAGGAGCACCAGCGCAAGCACTCGGGAGAGGCAGCGTACGCTTGTGCTGTGTGCGACAAGAGATTCCCTCTGCGCCGTAGCCTGTCTGTTCATATGCACAAACACAACAATGCCGGAAAACACAAATGTGAGGAGGAAAACTGTTTTAAATCTTTTCCTTTGAAGTACCTCCTGGACTTTCATCAGCTAAAGTACCACTCCAGTGAAACACCGCATGTATGCAAGATTTGTACTAAAGGATTTTTAAGAATTGGCGATTTGAAAAGACACATGAAAATTCATCATCCCAATTTTGCTTTCGTatga
- Protein Sequence
- MTSIFEYEDNYKYFEKIQHCANINIAELDGYPSLICGDCRAELSIAYVFVTKCQNSDKYLRDSKLEVEVKVELDLSEDVSDRSCDLPDIASDEIFVKRENTSAQARKYKTNSKVRKRVKVKKEASDLQCATCGLLVASRAAMIIHVRRHTGERPYQCGQCGARFSQAGTLKVHAARRHAPPAGPRPRPFPCSHCGGRFYSRRDLTVHVRTHTGELPHGCAQCGRRFSQLSSLIRHKRTHTGERPYRCPEPRCGKAFTDRSMLRQHRSVHSEEKRYRCAVCGKAVKSQNTLNKHMSLHREAKPVMCERCGAAFSTKGNLSSHVRRQHGARSGQCSMCGREVPDLQEHQRKHSGEAAYACAVCDKRFPLRRSLSVHMHKHNNAGKHKCEEENCFKSFPLKYLLDFHQLKYHSSETPHVCKICTKGFLRIGDLKRHMKIHHPNFAFV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -