Basic Information

Gene Symbol
-
Assembly
GCA_031772225.1
Location
CM062869.1:15363344-15372265[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 28 0.2 16 7.2 0.9 1 23 132 154 132 154 0.97
2 28 7.2e-06 0.00059 21.1 5.6 1 23 160 182 160 182 0.99
3 28 1.7 1.4e+02 4.2 0.8 1 23 188 210 188 210 0.93
4 28 0.0083 0.68 11.5 2.8 1 20 216 235 216 237 0.94
5 28 7.3e-05 0.006 18.0 0.8 2 23 244 265 244 265 0.98
6 28 0.11 9.5 7.9 2.5 1 23 271 294 271 294 0.97
7 28 6.2 5.1e+02 2.5 10.0 1 23 300 322 300 322 0.97
8 28 0.0021 0.18 13.4 0.8 1 23 329 351 329 351 0.98
9 28 0.081 6.7 8.4 3.2 1 23 376 398 376 398 0.95
10 28 0.0022 0.19 13.3 2.1 1 23 404 426 404 426 0.93
11 28 0.00099 0.081 14.4 4.1 1 23 441 463 441 463 0.97
12 28 0.00047 0.039 15.4 0.8 1 23 483 505 483 505 0.98
13 28 0.17 14 7.4 3.6 1 23 562 584 562 584 0.97
14 28 0.00032 0.026 16.0 4.2 1 23 590 612 590 612 0.98
15 28 0.11 9.5 7.9 1.6 1 23 618 640 618 640 0.96
16 28 1.9 1.6e+02 4.1 0.2 1 20 646 665 646 667 0.93
17 28 0.016 1.3 10.6 0.1 2 23 672 693 671 693 0.95
18 28 2.4 2e+02 3.8 1.8 1 23 848 870 848 870 0.97
19 28 0.00024 0.02 16.3 2.2 1 23 876 898 876 898 0.95
20 28 0.00025 0.02 16.3 0.8 1 23 904 926 904 926 0.97
21 28 2.1 1.7e+02 4.0 0.7 1 19 931 949 931 951 0.87
22 28 0.0063 0.52 11.9 0.3 2 23 959 980 958 980 0.96
23 28 0.04 3.3 9.4 0.3 1 23 986 1008 986 1008 0.96
24 28 0.068 5.6 8.6 4.1 1 23 1013 1035 1013 1035 0.96
25 28 0.099 8.2 8.1 1.7 1 23 1128 1150 1128 1150 0.98
26 28 1.9e-05 0.0016 19.8 3.7 1 23 1156 1178 1156 1178 0.98
27 28 1 83 4.9 3.0 1 23 1184 1206 1184 1206 0.96
28 28 0.059 4.9 8.8 0.9 1 20 1212 1231 1212 1233 0.94

Sequence Information

Coding Sequence
ATGGCAAACTTTGTTTATCCGACTCCAACCCACAGCCTCATGAATATGGATCAAAGTCATCTTTACAGAACGAAACCGCTCAATATGGAGCAGCACTCGACGTACAATCATTATAATATCGCATCAATGGACTGTAAACCGTCGCGGGAAAATTACAACATGACAAACCAATTTGCCGATTATTACAACATGCAACACGGAGAACCTTCGCAGAATTTTATCGCTCCAATGGTAGAAGAACAGAAACAAGATACAAACTTCTACAGCAAAACTGAAACTGCAAATATTCAAACTTCTCAACTTCAGTGTACAGATACAAGTCTTCAAAATCAAAACATTCCAGCTCCGACGTCAAATAAGAAGTCTATTCTGTTCAAAAAGAcaaatggattattttattgCGACCTCTGCGACTATTCCAGCCAGAAAGTCAGCTCGGTGAAGTCTCATCGCATGATCCACACCGGGGAGAGACCTTTTAAGTGCGACCTCTGCACCAAGTCGTTCAGACAGAAGGAGCACTTGAAAAATCACCGACTCACGCACACCCGAGAGAAACTGTTCTTCTGCAACGAATGTCCGTACTCGTGCGGCGTCAGGGGCAGCATGGACTTGCACAAACTGATCCACAGAGGAATTAAACCGTACGTTTGCACCAAATGCGACTATCGTTGCCGCAGACCATTTGAAATGAAGAAGCACCGCGCTAAATGCGAGAGCATCCTCAGAAAGTGCGACTCGTGCGACAGAACCTTCTCGAAAAAGAGCGCTCTGGCAATCCACCGGATAACGCATCtggagtatttaaaatttacttgtcAGCTTTGTGATTACACGGTCAAGCTGCGGTCCCGGTTCAAAAGTCACTTGAGCAAGATGCATCCGGAGAAGACATTTTTCATTTGTCAGTCGTGCGAATTCTGCTGCACAAAGAAGAGGTATTTCAAAAAGCACAAGTTGACCCACACAGATACAAGAAAGTGGTTCAAGTGTGACTCTTGTTTGTATTCTAGTTCTACGAAGAGCGCACTGAAGGAGCACGTGCTCACACACACAGAAGATAATACACACAATGACGCCTTAAATCCAGATGagCCCGCTCCGGTCAAGGATCCCAACTGCCTGTACTACTGCGACATCTGCGATTTTTGCAGCAGGCGGCTGAGCTCGGTCAAGGTTCACAAATATCTTCACACGGGCGAGCGGCCGTTCCTCTGCGACGTGTGTCCCGCCAGTTACACGCGAAGGCAGCACCTCCAGAAGCACAAAACCCTCCACGCCAATGGCAAGGACGCCAAGGTGGCCAAGCCAATGAAGCTGTTCACGTGCGACGTGTGCAGTTTTTCCTGCGCGCACAAGGGCAATCTTCAGAAGCATCAGCTGCTTCACGCAGAGAAGGATCCGAATTGTGAGAATCACGGAGCTATTGTTGCGCGCGTCAAAAAGTTCCCTTGCAATATTTGCAAGCTGAAGTTTAGTCTGGAGAATCAGCTGGTAAAACATCTGAAATCTCACATGGACAagGCAAACAACGGGTCAGCCGTACATTTCCAGTACGACTCCAACTCTGACAAATCTTTGCTAGATCAATATAACGAATTCAGCAAACTGAACAATATCGTACGGCAAGGCGACAAGACGAGTGAGAGATACATAGACATTTGTAAAAAGATCAACGAGGTCTACTGCTGCAATCTGTGCGACTTCACAACTAAAAGACTAACCTCCATCAAGGTCCACTATTTGATGCACACGGGGGAAAAGCCCTACAAGTGCGACATGTGCACGGCCAGCTACCGGAGGAAGCAGCATCTTCAGAACCACAGGATAAGACACACGAAAGAGACCATGTACCTGTGCCACCTATGCGACTTCACCAGCGTGCTCAAGTCCGGCATGGAGGTGCACAGAAAAACGCACGATGACGCCAAAATGTTTATCTGTGACATGTGCGATTTTGCGTGTTTGAATTCAAACGAACTCGAAGCGCACCGGGAGAACTGCGAGCTGCAGATGTGCAGCATGTGCCCGGAGATATTTTTCGATCGGAACAGCCTAGAAGCGCACGAGGCGAGCCACGAGGTCAGCCGCGAGGAGAGCCACGAAGCGGGCAGGAATCTGTGTAAACGCGAAGATAAATCATGTCTTGATGAGCGGGCTAATCTTGATAAGCCCTTGACCCGGCAATCGGCTCTTAAAACTCAGATTgtgaaggcaaTCGAATCGAAGTCCGCAAACGAGGATTTAgacaatgtatttaaactagAATTCGACAGAGTCTCGTTGAAAGAAGAGAGTTGCGACAGCGGATCCAACTTCAGCGATGACATGGACCGTCGGCCGGACGATTTCGGTCACGACGACAGCGACAACAACGATGTGAAAATTCCGAAAGAAGAAATCCTGAACGACGAAGCCTGCAGTGAAGAAGTAACAGACGACAgttgcataaaaaaattcaaaaagccgAAACGTAGAAAAGTTGTCGATTACACAATTAGAAAGTATAAACGCAACCAGCATAAGAGGGTCAACGGTCTGTATCATTGTGAATTCTGCGATTACGCAAACAAGCGTCTCAATTCTGTCAAGGTGCACCGCATGATCCACACCGGAGAACGTCCCTTCCTCTGCGATGTATGCTCGGCGACGTTCCGGCAGAAGGAGCATCTCATCAATCACAAAAACACCCACACTACCGATAAGACGTTCTCCTGTGAACAGTGCGGCTTCACGACCAAGCGGAAAGTGGGTCTAATAAAACATCAAATGCTCCACAAAGAGAAATCTTTCGTTTGCGTCAAGTGCGGCTACCGTTGCAGGATGAAGAGCATCCTCGACAAGCACGAAATTGCGTGCAGGGACAAGGTGTTGAAGTGCAACATGTGCGACGAGACGTTCCTTACCCAGAGCGAGATGGTCAACCACAGAATCGTCCACATCGAGCTGAAGACGTACAGTTGCGAGCTGTGCGACTTCTCCGCCAGTAATCTGCTGTACCTGAAGCGGCACACCGTGGTGCACTCCAAGGTGCTGTATCTCTGCTACATCTGCAGTTTCACCACCGTCCACAAGACCAACATGCAGAAACACAGGCTCACCCATAATGAGAAGAGCGATCGCGGGGATGAGCCGGCAGATGGACCAGCTCTGGAATTGAAGGAACATCATGTGGAAGAGAGTCCGCACAATTTGAGTGAGAGGAGTGAAGTAATGAAACATGTTGAACATGAGAAGACTTCCACAAAAAtggTATCGTTGATAAACTCTGAAATGCAGGTGCTGGAACCCATCTTCCAACGGCCGTACCAAGATCCGCCCAAGCAGCAGGGCCGACCGAAAAAGTACAAAACGGGAGAGTTCAAAAAGGAAAACGACCTGTACTTTTGCGACTTCTGCGATTACTCCAACACGAGAGTCAACTCGCTGAAGGTGCACAGGATGACCCACACGGACGAGCGACCCTTCTCGTGCGACCTCTGCCCCAAATCATTCAGACAGAAGATGCATCTGAGGAATCACAAGATCACGCACACCAAGGAGAAGCTGTTCTTCTGTAATATTTGCAGCTTTTCTTGCGGATACAAGGCCAGCCTGGACCTGCACAAGTTGAAACATACCGGTGTCAAGCCGTACGTGTGCGAGAAGTGTCTGTATTCGTGTCGGAGGCCTGTCGAAATGGAGAGGCACGAAAAGTTCCCGGACTCTTCTATCCTGCTCCAGTTTTCTTCTACACAGTCAGTCCACCTCTTGATCTGCATCTAG
Protein Sequence
MANFVYPTPTHSLMNMDQSHLYRTKPLNMEQHSTYNHYNIASMDCKPSRENYNMTNQFADYYNMQHGEPSQNFIAPMVEEQKQDTNFYSKTETANIQTSQLQCTDTSLQNQNIPAPTSNKKSILFKKTNGLFYCDLCDYSSQKVSSVKSHRMIHTGERPFKCDLCTKSFRQKEHLKNHRLTHTREKLFFCNECPYSCGVRGSMDLHKLIHRGIKPYVCTKCDYRCRRPFEMKKHRAKCESILRKCDSCDRTFSKKSALAIHRITHLEYLKFTCQLCDYTVKLRSRFKSHLSKMHPEKTFFICQSCEFCCTKKRYFKKHKLTHTDTRKWFKCDSCLYSSSTKSALKEHVLTHTEDNTHNDALNPDEPAPVKDPNCLYYCDICDFCSRRLSSVKVHKYLHTGERPFLCDVCPASYTRRQHLQKHKTLHANGKDAKVAKPMKLFTCDVCSFSCAHKGNLQKHQLLHAEKDPNCENHGAIVARVKKFPCNICKLKFSLENQLVKHLKSHMDKANNGSAVHFQYDSNSDKSLLDQYNEFSKLNNIVRQGDKTSERYIDICKKINEVYCCNLCDFTTKRLTSIKVHYLMHTGEKPYKCDMCTASYRRKQHLQNHRIRHTKETMYLCHLCDFTSVLKSGMEVHRKTHDDAKMFICDMCDFACLNSNELEAHRENCELQMCSMCPEIFFDRNSLEAHEASHEVSREESHEAGRNLCKREDKSCLDERANLDKPLTRQSALKTQIVKAIESKSANEDLDNVFKLEFDRVSLKEESCDSGSNFSDDMDRRPDDFGHDDSDNNDVKIPKEEILNDEACSEEVTDDSCIKKFKKPKRRKVVDYTIRKYKRNQHKRVNGLYHCEFCDYANKRLNSVKVHRMIHTGERPFLCDVCSATFRQKEHLINHKNTHTTDKTFSCEQCGFTTKRKVGLIKHQMLHKEKSFVCVKCGYRCRMKSILDKHEIACRDKVLKCNMCDETFLTQSEMVNHRIVHIELKTYSCELCDFSASNLLYLKRHTVVHSKVLYLCYICSFTTVHKTNMQKHRLTHNEKSDRGDEPADGPALELKEHHVEESPHNLSERSEVMKHVEHEKTSTKMVSLINSEMQVLEPIFQRPYQDPPKQQGRPKKYKTGEFKKENDLYFCDFCDYSNTRVNSLKVHRMTHTDERPFSCDLCPKSFRQKMHLRNHKITHTKEKLFFCNICSFSCGYKASLDLHKLKHTGVKPYVCEKCLYSCRRPVEMERHEKFPDSSILLQFSSTQSVHLLICI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-