Esep002630.1
Basic Information
- Insect
- Eristalinus sepulchralis
- Gene Symbol
- PRDM15
- Assembly
- GCA_944738805.1
- Location
- CALYJE010000018.1:4202837-4207796[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 27 9.8 1.1e+03 0.6 0.4 2 9 168 175 167 175 0.88 2 27 0.015 1.6 9.4 1.9 1 23 206 228 206 228 0.98 3 27 2.4e-06 0.00026 21.4 1.6 1 23 235 257 235 257 0.98 4 27 2.2 2.4e+02 2.6 0.1 2 23 286 308 285 308 0.91 5 27 6.2e-05 0.0067 16.9 2.2 1 23 378 401 378 401 0.95 6 27 0.0047 0.51 11.0 2.8 2 23 470 491 469 491 0.97 7 27 8.9e-05 0.0097 16.4 1.1 1 23 498 520 498 520 0.96 8 27 0.88 96 3.8 0.1 2 23 533 554 532 554 0.94 9 27 0.11 12 6.7 1.1 1 23 627 650 627 650 0.92 10 27 0.88 96 3.8 0.7 1 20 659 678 659 680 0.93 11 27 0.044 4.8 7.9 5.0 1 19 688 706 688 709 0.95 12 27 0.0016 0.17 12.5 3.4 2 23 720 741 719 741 0.98 13 27 1.4e-06 0.00015 22.1 0.7 1 23 748 770 748 770 0.98 14 27 0.0029 0.32 11.6 2.6 1 23 906 929 906 929 0.97 15 27 0.0086 0.93 10.2 1.4 1 23 966 989 966 989 0.94 16 27 6.9e-06 0.00075 19.9 1.0 1 23 1028 1050 1028 1050 0.98 17 27 5e-05 0.0054 17.2 1.5 2 23 1074 1096 1074 1096 0.97 18 27 0.0015 0.16 12.6 2.0 1 23 1137 1160 1137 1160 0.95 19 27 2.5 2.7e+02 2.4 3.4 1 22 1167 1188 1167 1188 0.92 20 27 0.11 12 6.7 0.8 1 23 1197 1220 1197 1220 0.93 21 27 0.02 2.2 9.0 2.0 1 19 1226 1244 1226 1246 0.96 22 27 3.5e-05 0.0039 17.7 1.4 1 23 1256 1278 1256 1278 0.98 23 27 1.1e-05 0.0012 19.2 0.3 2 23 1298 1319 1297 1319 0.95 24 27 0.00037 0.04 14.5 4.3 1 23 1325 1347 1325 1347 0.99 25 27 1.1e-07 1.2e-05 25.6 3.6 1 23 1353 1375 1353 1375 0.98 26 27 4.3e-07 4.6e-05 23.7 2.4 1 23 1381 1403 1381 1403 0.99 27 27 0.00035 0.038 14.6 0.2 1 23 1409 1433 1409 1433 0.92
Sequence Information
- Coding Sequence
- ATGCTGCAGTTGAACAGTGCAAATATCGGTGAAATATGTCGGGCATGTTTCAAAGTATGTGAGGATTACAAAATGTTGTTTGAAGAATCGGAGACTAGTGATAAGCTCACACTGGGTGATGTCTTCAGTCAAGTTGTAAAAATCGAAGTAAAGGCTTGTCCAGAAAATGCGCCGACAAGAATTTGTCTTGATTGCGTAAAAGATTTGAACATTGCTTTCAACTTTATTCAAAAATCACAACAAAACAACGAAAACTTGCAACAGTTCTTGAAAAATGGATCTGTAAAACAACCAGACTGTCTTTCTGAATTTCCCATCGACATTCCGACTGATACAAACACTGCTGATTTCCCAGAAGTCAAAACCGAAAATGAATTGTCCAACGACTATGAAGAAACTTTTTCGGATGTTAAAATATCTGCTTCAGAAAAATCAGAATCAGCAGATACAGAACATGATGAAACGCCGCCGTCAAGCGAAGAAAAGAAAATCAAAAGGATGCAATGTACTTACTGCGACCGAACCGACGCAGAGGATAAGAGAACAACACGAAGTCAGCGACTCAAAATGAAGACACGAAGTCAAAGTAAGCAGCTTAAGACAACCTCCGGTCGCTTTGAGTGCGATTCCTGTTTTAAAACTTTCGCTTGGAAAAAAGATTTGTACAGACATGAGCGATACCACGAACCCAACACGAAGAAGTTTCCCTGCCCTCATTGCGATCGCCGATTCATACGAAAGGATAAGCTTTCATCACATCTTCAAGTTCACTTGACTGGATTGAACAACTCAACTACATTGAAAAGTTTTCAAAATTTTGCAAATCTGTATTCCGAGAAAAAATTTAAGGAAATCAAGTGCATGATATGTAGTTTAGAAGGATTTCCCAACGTTCATGGTCTACGACAACACATCGCATTGCATAACAATTTAAAGTTAGTTGACGATCTAACTGGCAGTCTCGTGATGGAAAGGTTCTTTCCGAACATGGACTTGAAGGACGTGCAATTAAACTTGAATGAAGAAATGAAACAAAAGAAATTCGCAAAGCTTCATTCAATAGTGAATGGTAACAGTTATGAAATGGGAATAAGTGATTCTGATGAGAGTGATCCAGACTGCCAACATCGCTACAGTTGTGAGGTATGCAGTGAGTCATTTAGCAGAAAACACAAACTCATGACACACCAGGCGTATGAGCACTCATTCGATGACTGCCCCTACGAGTGCGAAGTGTGCAAATTAAAATTTACTTGTAAGGAAATATTTCAAAGTCATCGCAAGCACCATTGTGAAAATCCCGACCGGCAATTCCATTGCCAACAGTGTCCGGGACGATTTACTTGGCTACATAACATTGAAAACCATAAATGTAGGAAGAAAACTTCTCTCAATAAAGAGAACAGTAAATGTGAAATATGTAATAAAATGTTTGCTTGCTCTAGAGATTTAAGACTTCACAGAAAGATACACATTCCAGAGGGAAAGTCACACGACTGTGCCATATGTGGGGAGAAATTCTATCGGTATGAAAGCCTGCGGTATCATATGATTTCACACAGTTCGGAAGACGATTTGTTGGCTTTGAGGAAAATATCATGTATGCTCTGTAACACAGAGTTGTCGGGGATAAGCGGTCTCAAAACCCACTTGTTGCTGCATGCCGATGGGCAAGTGGACTTGAAGAATTGTAAATTCGCACAAATTTTTTATCCAAATGCAGATGAAACTGAGGTCTCGGAGGCGATTAGAAAATGCTTTGAAGAAAAACAGCTTGGTAAGCTTTATGTTGGGATAGATAAATTTGGTCTCGAAATAGCTTTGAGTGATTCAGATAGTGGCGACGAAATGAAGCCGATTGGAAATTACTCAAAGACCTTCACTTGCGAGCTGTGCCACCTGAAATTTCCCCGAATGCAGTCGATATTCGAGCATCAGATTGCACAGCACGATGATTTTATTATGAATACACCGTACACATGTGATAACTGCAATGATCAATTTGTTTGCAAAGAACTTTTGCAGAAACATTTAGCAGTCGGTTGCTTAAGTACAGATAGCTTTTCTTGTTCCAAGTGTGGATGTAAGTTTGTTTTTAAACAGAATTTGTCTGCTCACAACTGTTTAATAAGTGAAAAAAGCTCAGAAGATGCTAAACAGTGTGAGATTTGCGGAAAGAAGTTCAATTGGCTTAAGGATTTGCACAGACACAAACGTAGTCACGTTCCCGATGAGAAGAAATTCGAATGTCTAGTGTGTGGAAGAAAATTCAATAGAAAGGATAATATGCGAGCACATTTAAAAGTTCACAATGTGGACTATAAGATGCGATCAAAAACCATGCTTAAGTGGGAGCAACAGGACGAGAACATGTGTCGTCCGCATGGTGAGAAAATTATACAGTGCAAAATTTGTCTATCAATCCACAATTCCATTCGAGATTTGAGCACTCATTTGCTGATTCACAATGATTGTAACACATTAAAACAGAAGGATTCAGAAGTCAAGGAGGTATCGATGATCCTCTATAACAAGCCAATGGATCTACGAAATCTGTCTAAAGCAATCTGTAAGGATCTATCAGACGGCAACCATAGTCGCTTCTATTCGATTACGAACGAAATGGGCTATGAGTTGAGTTTGATTGATTCGGAAACAGCCACTGACCTGGATGCAGATGATGATGAGGAGGAATGTAATGATGTCCGCAAAGGTTACACCTGCATGTTATGTAGCAAAGTGTTTAACAGAAAATTTAAGATTTTCGAACACCAAAGACAGGATCATTCCTGGAGTGAACTACCACTGGAGTGCTCATATTGTTCGGCAAAGTTCGTGTGTGAGAGCATATATAACCAGCATATGAAGTACGAATGCGAAAACGCTGAGAAACAATTCAAGTGCAAGCTGTGTCCATTGAAATTCGTCTGGAAAGAAAATCTTAAAAATCACGAGAAGTTTATGCATGATAAAAATCCAGTATTTGCCAAGAAACATCATTGTGGCACATGCGATAGAAGTTTTCTGTGGCACAAGGACCTACTAAGGCACAAAAAGAGCCATCGTGTGGAGGAAGAAAAATTCGAGTGCACCTGGTGCTTTCGTATTTTCATGCGCAGGGATAATCTTAAGGTTCATATGAAAGTTCATAAAAACGCAACTCATCTCCTGCTGCCAGACATCTACTACTTGGCGCGACCGAACAGCACCAAAGTAGCCGAATGCAAACATTGCAATCAGAAGTACACGACTGCCGGAGATTTGCTTCAGCATATTCGGAGCATGCACTTGAGTTTCCAACTGCAACATGCTGTACCAGAACCAACTAGTTATTCCATAACGAATGCTTTGGGCTACGAGATGGACATTGAGGATTCAGAAACCGAAAGAGAAGAGCCAAATGAGAAATACTCTTGTGAACTTTGTGAGACGCGCTTCAATCGACGTTTCAAGTTGTTACAACATCAGCAAGCTTTCCACTATTCTGATAACATACCACACAAATGTGATCACTGTAACTTCAAATGTGTATCCGAACCTGTCCTAGCTTATCACAAGCGTACCCAGTGCATGAACACTGTCAAGCAATTCCGCTGCAGCAAATGCACAATGCGTTTCATGTGGCGTCAAAACCTGGAAAACCACGAGAGCATCATTCACGATAGTCCGCGGACACACACTTGCGAGGTGTGTAAGCGAGATTTTGCAACGCTACACGATTTTAAGAACCACAACGAATGCAAGCCCCCAGCCGAAGTGAAGTTATTCGAGTGTGATATGTGTGATCGGAAGTATAATCGTAAGGATCGATTGATGAAACATGTGAAGGTTCACAATGAGAAGAATAAAGAACAACGAATGAAAACTGTcacatcaacggataagaaattcctgtgtgccttttgtggtaaggaggtttccagctcctcgaatctggtcattcatatgcgtcggcacacaggagagaaaccgtttaaatgtgaattctgcaacaagggctttccacgatcttcggatttgagttgtcacagacgtacgcataccggagaaaaaccacataagtgcacggagtgcgataaagcattttcacgttcgtacaagctacaaacgcatatgcgaattcattctggggagagaccttataaatgtacatattgtgagaaaagctttacacagtctaatgacttgacgcttcatgtacgcagacacactggagaacgtccgtacatatgtgaaacatgtggtgagagattcatacaAGGGACAGCGCTAAGAAATCATCGGAGGATGAGAGGCCATTATGCGGTTTGA
- Protein Sequence
- MLQLNSANIGEICRACFKVCEDYKMLFEESETSDKLTLGDVFSQVVKIEVKACPENAPTRICLDCVKDLNIAFNFIQKSQQNNENLQQFLKNGSVKQPDCLSEFPIDIPTDTNTADFPEVKTENELSNDYEETFSDVKISASEKSESADTEHDETPPSSEEKKIKRMQCTYCDRTDAEDKRTTRSQRLKMKTRSQSKQLKTTSGRFECDSCFKTFAWKKDLYRHERYHEPNTKKFPCPHCDRRFIRKDKLSSHLQVHLTGLNNSTTLKSFQNFANLYSEKKFKEIKCMICSLEGFPNVHGLRQHIALHNNLKLVDDLTGSLVMERFFPNMDLKDVQLNLNEEMKQKKFAKLHSIVNGNSYEMGISDSDESDPDCQHRYSCEVCSESFSRKHKLMTHQAYEHSFDDCPYECEVCKLKFTCKEIFQSHRKHHCENPDRQFHCQQCPGRFTWLHNIENHKCRKKTSLNKENSKCEICNKMFACSRDLRLHRKIHIPEGKSHDCAICGEKFYRYESLRYHMISHSSEDDLLALRKISCMLCNTELSGISGLKTHLLLHADGQVDLKNCKFAQIFYPNADETEVSEAIRKCFEEKQLGKLYVGIDKFGLEIALSDSDSGDEMKPIGNYSKTFTCELCHLKFPRMQSIFEHQIAQHDDFIMNTPYTCDNCNDQFVCKELLQKHLAVGCLSTDSFSCSKCGCKFVFKQNLSAHNCLISEKSSEDAKQCEICGKKFNWLKDLHRHKRSHVPDEKKFECLVCGRKFNRKDNMRAHLKVHNVDYKMRSKTMLKWEQQDENMCRPHGEKIIQCKICLSIHNSIRDLSTHLLIHNDCNTLKQKDSEVKEVSMILYNKPMDLRNLSKAICKDLSDGNHSRFYSITNEMGYELSLIDSETATDLDADDDEEECNDVRKGYTCMLCSKVFNRKFKIFEHQRQDHSWSELPLECSYCSAKFVCESIYNQHMKYECENAEKQFKCKLCPLKFVWKENLKNHEKFMHDKNPVFAKKHHCGTCDRSFLWHKDLLRHKKSHRVEEEKFECTWCFRIFMRRDNLKVHMKVHKNATHLLLPDIYYLARPNSTKVAECKHCNQKYTTAGDLLQHIRSMHLSFQLQHAVPEPTSYSITNALGYEMDIEDSETEREEPNEKYSCELCETRFNRRFKLLQHQQAFHYSDNIPHKCDHCNFKCVSEPVLAYHKRTQCMNTVKQFRCSKCTMRFMWRQNLENHESIIHDSPRTHTCEVCKRDFATLHDFKNHNECKPPAEVKLFECDMCDRKYNRKDRLMKHVKVHNEKNKEQRMKTVTSTDKKFLCAFCGKEVSSSSNLVIHMRRHTGEKPFKCEFCNKGFPRSSDLSCHRRTHTGEKPHKCTECDKAFSRSYKLQTHMRIHSGERPYKCTYCEKSFTQSNDLTLHVRRHTGERPYICETCGERFIQGTALRNHRRMRGHYAV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -