Basic Information

Insect: Eristalinus aeneus
Gene Symbol: PRDM1
Assembly: GCA_955652365.1
Location: OY019134.1:76073852-76077782[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 2.2e-05 0.0032 18.5 2.5 1 23 784 806 784 806 0.99

2 5 6.7e-06 0.00096 20.1 5.1 1 23 812 834 812 834 0.98

3 5 1.4e-06 0.0002 22.3 4.3 1 23 840 862 840 862 0.98

4 5 0.00046 0.067 14.3 2.4 1 23 868 890 868 890 0.97

5 5 7.9e-05 0.011 16.8 0.1 1 22 896 917 896 917 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	2.2e-05	0.0032	18.5	2.5	1	23	784	806	784	806	0.99
2	5	6.7e-06	0.00096	20.1	5.1	1	23	812	834	812	834	0.98
3	5	1.4e-06	0.0002	22.3	4.3	1	23	840	862	840	862	0.98
4	5	0.00046	0.067	14.3	2.4	1	23	868	890	868	890	0.97
5	5	7.9e-05	0.011	16.8	0.1	1	22	896	917	896	917	0.96

Sequence Information

Coding Sequence: ATGATCAATAATACTATGGATACTGCATCGCAATCAACAGCATCTATCTGCCCGCCCAGCAGCAATCGGAGTCCTTCACCAGATGGCACACAGGACTACGATGTGACTCGCATGAAGGAGGAGGATTTCGAGCGGTTGGCGGTTTACATTGTGCCCGACGTCCAATGTGAACGGGGTGTACCCAACAGAGCAGATAAGACTCTGCCACGGAGTCTAACATTAAAGCCATCGATGGTGTTATCAACGCCAAATGTCAAGACTGAAGGAGTATGGAGCACCGGTGTTATACCGCGTGGAACGAGGTTTGGGCCATTCGACGGCGTTCCAACTCCTAATTATCCCAACGATAAAAATGCCGCAAGATACTTTTGGCGGGTGCAGGGACAGTGTCATGTTACCTATGGAAACATCAAGATCTTCAAGGACGATGATTTCTACTACCTAGACGGTTCGGATCGGTCCCAATCAAACTGGATGCGATATGTTGCCTCTGCATACAGCCTCTCCGTAATGAACCTAGTTGCATGCCAGCATCAGGACAATATCTACTTCTACACAATTCGCGATATAATGCCTAACGAGGAGCTTATGGTGTGGTATTGTAAGGACTTTGCGAAGCGACTCGGCTACGATGTGGATCCTGAACGCGTCACGTACAGCATTTGTCAGAGTAAGGAGGAGGAGCCTGATGAGGCGCCATCGGCGATCAAGAAGAACTACGCCTGCATGCAGGCACCAGAAATTCCGCCCGAAGTTGCTTACAATCATATCACCTACGTTATGGGCTTGCACATTCCGCCACGAAGAGGTTCACTCACACCGAGTCCATCGCCACCGATCACATCCACAGCCACAAGTTCGCACCACTCTCATCTGCAACATCAGCTTCAACTGCAGCACCCACAACAACCACAGCAcctgcaacagcagcagcagcagcaaccccACTTAAGGCACACAAACAGCCACCAGAGCGTCCTGCATTTAAAGCCTGAGCCAGATCAAAACCGCATCCAAGTGATCGTGCGCGATCGGTCTCCGTCGGTGAGCGACTGCGGCAGTGGCAAGGACAAGGACGTCCAGTCGCCGATCTCGCATAAAGGCGACGCTCAGTACGAGCACCAGCTAACCCCGAACGACGGATCGGTGCGGTCGGTGCGTTCAGATGAGGGCTACCATAGCAATGAGTACCATGAAGATGGACTGACGCCACCGGAGGATTCAAGCGACAGCGAGGAGAGCGAGCACAACTACGTGTTAGATTGCTCAAAGAAAGCCATCGAACCCAAAGAGACTGTAATCACACAAAAACTCAACGATTGTGATAAGAACGAGTACCGAAAGTTCAAGGTGAAGTTGCCCTTGAAGTATGAGTTCAAAAATAGTAAATGCGTCAAGACTGAAATCGATAAGGACAGCGTCGTCACGGGTGTGACAACTACGTCAGCAGATGAGGAAATGGTTCTGACCACCCTTACGACTGCGCCGCTGGATGAGGAACTTGTGAAACGAGTCACATCGGCCACAACCACGACCACCCCTGCCACGAGTACAGTGATCGTGCTGGAAGGCAGCCAAGAGCCCCACACAATCGTTCCTCTCAACAAGCCGTACTACGAAGCCGAGACTTCATCCCCGCCACCACAAGCATACATGCGATTTACCCCACCTAGTTCAAGTATACTTGAAACCATTCTGACGGGCAGCAGATCAGCTGCGGGAAGCATGAGCATCGATCAGTCTTCTCGTCGGCAGCCAAACGCCACCCCTCCCCCAACGTCTCCCACTGAGATGGCGTACTCATACAAGAAATCGCAGCGCTACGGGAACGCTGTGAGCCCAGACTCTAGTTCTAATCTAGCTCAACCGCCGCCGCATATTCACGATGCCGATATTGTTATGTCATCATCGAGAAACAGTCTGAAAAACGAAAGCCCACAACCGCAAAACATTGTGTACTCCACAACACAAACGTTCCAAGATGGCCACCAGACCCCACCCTACAGCGCGTATGCTTCCTACTCAGCAAACGGCACTAATGTCATATCACATGCCCCCACATCGACATATTCACCACCGCACAGCAACAGTCCCTTCGATCGGAGCTCGAACGGAGGCCGGTCCACGCCAAATCTCCATCTCCTACAGAACAGCACACAGATGCTCAGCCATCCTCTGATGCAGCCACTGCAAAGGCTCTCCCCTCTGCGTATATCGCCACCTAGTAGCTTAAGTCCGGACGGTAATTCGTGTCCCCGTAGCGGCAGCCCGTTGAGTCCGAACTCGCTGGGCTCACGTGGCTACCGCTCCCTGCCGTACCCGCTCAAAAAGAAGGACGGTAAGATGCACTACGAATGCAACGTCTGCTGCAAGACATTTGGCCAACTCTCCAACCTGAAGGTCCACCTCCGCACGCACTCAGGAGAGCGGCCATTCAAATGCAATGTCTGCACGAAATCCTTCACCCAGCTGGCACACCTACAGAAGCACCACTTGGTACACACAGGCGAGAAGCCCCATCAATGTGACATCTGCAAGAAACGCTTTTCATCGACATCGAACCTAAAGACACATTTAAGACTGCACAGTGGACAAAAACCGTATGCCTGCGACTTGtgtccacaaaaattcacccagTTTGTGCACCTGAAGCTGCACAAGCGCCTGCACACAAACGACAGGCCGTACGTATGTCAAGGATGCGACAAGAAGTACATCAGCGCATCGGGACTGAGGACTCACTGGAAAACCACAAGTTGTAAGCCCAACAACCTGGAGGAGGAGCTAGCCATGGCAGCGGCCGCCACATCTGAGTGCTTAGGTCCAAACGACAAGGACCACCCAGAGCCCGACTCCCGGGAAGCCTATGAACTTCAGCAGCAGATCCATGCCCACACCCATCCTCACCTGCGCCACATTGGGCACCATTCACCCCCTCGACTGATTCAGATTCATTCACAATCGCCAACCACAAACCACCACCCTATGATCCATCAAATGCCCGCGCCTTCCTCCCAGTCAACTCAGCCGCAGCAACAGGGGCTGCACCACCAACAGCACTCGCAACAACTTCCCCAGCCGCATCTGAccatccagcagcagcagcaagtgGTGATGATTGCCAGTCCAAACGCTCACCAGCAACCaccgccgcagcagcagcaacaacatccaCCTCCCAATATGCTGCTGACAACCGCTTCACAACTGCCGCAACACAACCTCCCCCACCAGCATCACCAACATCACTTGCACCTTCAccaccagcaacaacagcagcaacaacaacagcaacaactccaacagcaccaacagcaccagcaccagcagcaccaAGCCATCAAGGCGTCGATGCAAAAGGGTCCAACCATCATGACACACGTCGTACAAACCACCGCCACAACGAATCCCAGTGACCAATACGTGGTAACAAGCCACGCGCACCAGCACTCGCATCCTCACTCGCAGTCACAGGAGTCCCGGCCCACAGTGATCGAGTCCAGCCAACCGATGATCATGGGGTGCACATAA
Protein Sequence: MINNTMDTASQSTASICPPSSNRSPSPDGTQDYDVTRMKEEDFERLAVYIVPDVQCERGVPNRADKTLPRSLTLKPSMVLSTPNVKTEGVWSTGVIPRGTRFGPFDGVPTPNYPNDKNAARYFWRVQGQCHVTYGNIKIFKDDDFYYLDGSDRSQSNWMRYVASAYSLSVMNLVACQHQDNIYFYTIRDIMPNEELMVWYCKDFAKRLGYDVDPERVTYSICQSKEEEPDEAPSAIKKNYACMQAPEIPPEVAYNHITYVMGLHIPPRRGSLTPSPSPPITSTATSSHHSHLQHQLQLQHPQQPQHLQQQQQQQPHLRHTNSHQSVLHLKPEPDQNRIQVIVRDRSPSVSDCGSGKDKDVQSPISHKGDAQYEHQLTPNDGSVRSVRSDEGYHSNEYHEDGLTPPEDSSDSEESEHNYVLDCSKKAIEPKETVITQKLNDCDKNEYRKFKVKLPLKYEFKNSKCVKTEIDKDSVVTGVTTTSADEEMVLTTLTTAPLDEELVKRVTSATTTTTPATSTVIVLEGSQEPHTIVPLNKPYYEAETSSPPPQAYMRFTPPSSSILETILTGSRSAAGSMSIDQSSRRQPNATPPPTSPTEMAYSYKKSQRYGNAVSPDSSSNLAQPPPHIHDADIVMSSSRNSLKNESPQPQNIVYSTTQTFQDGHQTPPYSAYASYSANGTNVISHAPTSTYSPPHSNSPFDRSSNGGRSTPNLHLLQNSTQMLSHPLMQPLQRLSPLRISPPSSLSPDGNSCPRSGSPLSPNSLGSRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHWKTTSCKPNNLEEELAMAAAATSECLGPNDKDHPEPDSREAYELQQQIHAHTHPHLRHIGHHSPPRLIQIHSQSPTTNHHPMIHQMPAPSSQSTQPQQQGLHHQQHSQQLPQPHLTIQQQQQVVMIASPNAHQQPPPQQQQQHPPPNMLLTTASQLPQHNLPHQHHQHHLHLHHQQQQQQQQQQQLQQHQQHQHQQHQAIKASMQKGPTIMTHVVQTTATTNPSDQYVVTSHAHQHSHPHSQSQESRPTVIESSQPMIMGCT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00389986;
90% Identity: iTF_00671777;
80% Identity: -