Edef004663.1
Basic Information
- Insect
- Erannis defoliaria
- Gene Symbol
- ZEB2
- Assembly
- GCA_905404285.1
- Location
- FR990094.1:507963-516765[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 24 0.13 11 7.3 4.1 1 23 170 192 170 192 0.95 2 24 0.0022 0.19 12.9 1.0 1 23 197 220 197 220 0.96 3 24 0.022 1.9 9.7 1.7 1 23 253 276 253 276 0.95 4 24 3e-05 0.0027 18.7 2.5 2 23 284 305 284 305 0.94 5 24 0.007 0.62 11.3 3.8 1 23 312 335 312 335 0.95 6 24 1.3 1.1e+02 4.1 6.5 1 21 430 452 430 453 0.88 7 24 1.7 1.5e+02 3.8 0.2 3 23 459 479 458 479 0.92 8 24 0.066 5.8 8.2 2.3 2 23 485 507 484 507 0.92 9 24 0.065 5.8 8.2 1.3 1 21 512 532 512 534 0.90 10 24 0.0006 0.053 14.6 1.0 1 23 569 592 569 592 0.95 11 24 5.1e-05 0.0045 18.0 1.9 1 23 598 620 598 620 0.98 12 24 0.89 78 4.7 1.2 5 23 630 648 628 648 0.96 13 24 2.1 1.8e+02 3.5 3.0 1 23 654 677 654 677 0.93 14 24 0.0023 0.21 12.8 3.6 1 23 685 708 685 708 0.93 15 24 0.00039 0.034 15.2 0.7 2 21 818 837 817 838 0.94 16 24 0.11 9.9 7.5 0.0 3 23 845 866 843 866 0.95 17 24 0.00052 0.046 14.8 0.7 2 23 872 894 871 894 0.94 18 24 5.7e-05 0.0051 17.8 2.4 1 23 899 921 899 921 0.98 19 24 0.27 24 6.3 4.0 2 20 925 943 925 945 0.92 20 24 3.8e-05 0.0034 18.4 0.6 1 23 971 994 971 994 0.95 21 24 0.098 8.6 7.7 1.1 1 21 1000 1020 1000 1022 0.81 22 24 0.091 8 7.8 0.1 1 23 1028 1050 1028 1050 0.97 23 24 0.0064 0.56 11.4 0.7 1 23 1056 1079 1056 1079 0.94 24 24 0.00021 0.018 16.1 0.4 2 23 1086 1108 1085 1108 0.95
Sequence Information
- Coding Sequence
- ATGAAAGAAAATTCCATCGAATGGGCGCCCAGCCTGCCGCCGCGCCTCTGCCGAGCCTGCACCTCTTCCATCTCCAGCTTCGTCCCCTTCTACATTCTCTGCCGAGAATCAGCCTTTAAATGGAACCAAGTCGCCACCTACCTTAGCACGGTCACAGTAAACAACCAGGCAACCACGGCGTACGTGCTGCTAGGCGACGACCCACAAACGGTCGTCGACCGAAGCACCTCCAAAAACAAAGCCCCCAAAGAAGTTATCAAGAATGTGAGAACTCGACTCAGTGTCATACGTCGCACGAGGCAGCGGATCAAAGCGAAAATCGCACCGTTCCGAGGAAGGGGCTCCTTCTATTTCTTTTGCCCGGATTGCAAGAAGGGGCCATTCGATAAGCTATACAAGTTTAACTTTCACTTAAATGTTAACAGGAAACAATGTTGTCCACATTGCTTTAAAATTATTTGCGTTACCGAGTTTGGGGATCATTTGGCTTCGCATGGACTCCCGAGCTTTGAGTGCAAAGTGTGCAATCTGCATTTTGATAAGGAAACGCGTCTGACGAAACACAAGCTGTTCCATTATAGGGGGAAGTACGAATGTTCTGAATGCAAGTACACCTACACTTCGATGGACAGACTTACCAGCCACACTAACCTCGTTCACGCTAAAACACGCTGCGCCTGCGACAAGCTCTTCTTCGCTCGGACCTGTTATCTGGGGCATAAGAAACGAATGTGCCACAAGAAACCTATACAGAAATTCATTTGCGACTTCTGCTCCAAAGAATTCGACCGCAAATTCATTTTACGTCAACATATACAAAACTTTCATAGCACGCCGGTATATACGGAACAGTGCGACCAATGTGGGAAGAGGTTTAAATCCAAAGCTCATTTGAAAGAGCATTATTACGCCCATGATAAAAAGCTGGATCGTTTCACTTGCGAGTATTGTGGTAAAAACTATAGTACTCCAAGGGGACACAGGCGACATTTGACCAAGAAGCATTATCAGGTTGACGAGGAGTCAGACTTGCCGCCTGGTCTGTGCCGGGAATGCACTGAGGACACCCTAGCGGCTGTGGCCTTCAGGCAGCTCTCGCAGCAATCGGCTCGGTACTGGCACGAGGCTACAGCCTACTTGACAACCATCAAGGACCCTACACTCAAAGACAAGACGTTCTTCGTCTTCTACCCTCAAGAAAAATCGGTCTACAACGTCACCGATCCCGCTTCCACGACAGAAAGCGCCGTGAGCGTCCTAAACAAGCCGAAAACAAAAAGAAAACGCTTCTCGTGCCATTGCCTAAATTGTAACAAAAAGTTTAGCTGCTTGGAGAATTTGAACGATCATTTGAAATATACTGCGCAGAGATTCTGTTACGAATGTGGTGTGGGAGTTGACAAGAAAAATTTGGCCACGCATTTGTCTTTAAGACACGGCGTTGAAGTTTTGGAATGTAAATCTTGCCATGAGATATTTCGGAATCATGTCGAAGTTCAAAGACATTGGGTCAAGAATCATGGGCCTGGGACACATTCATGCTCGCTCTGCGGGGCTGGGTTCCCGCACGAGCGCGGCCTTAGAGCTCACAGCTACTTCCACTCGCTCCTGCACTGCCCTTGCGGAGCAACCTTCGAAAACGCTCGCTGCCACAAGCATCACATAGCCAAATGCAAGCCTCAAAGGCACCAAACCGATTCTAACTTCGAATGCGATCACTGTGGTGTTATATACAATAAGAAGCCGTCGCTTCGCATGCACATGATTCAAAAGCACCTAAACGTACTCCCTTTCGTTTGTCAAACATGCGGAAAGCGTACTTCAACTCTTGGGCATTTGAGGTCCCACGCGCAAACTCACGAACCGAAACGGATTCTTCTCGAATGTCATTGCGGAGCCAAATTTCGCACTGATTTAGGATATAAGTTACATTTGCGGATCCATTCAGGGGATAAGCCTTATAAATGTGCCCAGTGCAAGGAATGTTTCCTTTCTGCGTCCCGGCGGTTGGATCATATCAAAAGACGTCACCAGTCTTCGAAGGACATGCCGCATTGTTGCACGGAATGTAATGCTAAGTTTATCAGGCCGTGGGAGCTTAAGAAGCACTATTTGAACACTCACGGCTCAGTCATCCCGGAAGATGATTCTTGTCCGATCGGCGCATGCGTGGGATGCGCGAGCGCAGCCCTCTCCGCGCAAGAGTTCCGCCTGTTCGTGCGGAACTCTGAAAAGATGTGGTTCAAAGCCATCTCCAACCTCTCCAACCTTGAATCTGATCAAGAGGAACGCGCCAAATCAATTTGCGCCTTCATCACACCCAACGATCTGACAGTGCTAACGGCTAAAGACTACATTGGAGGCAACGCGAGAGAAGTCGTCAACCGTTCCAAAACCACCGTCAAAAAAAGCAAACGGAGAAACAGGCGGCAACAAATAGGACCCTTGATCTCTTGCCCAGATTGCCAGAAGACATTTACAAGCCCATTTTTCTTGCATGAACATTTAAAGAATAATGGGCCAAGAACAGCTTGCCAAATGTGCGGGGCTGTGGTGACTAGGGGTCCAGAGCTGATAGAGCATATGGCAGTCATTCACAGAGAGACCCTGATCACGTGTCCCCAGTGCCCTTGCTCGTTAAGAAGTCGAGAAGATTTGAACCAGCATATGAAAGATGCTCACAGAACTGGCGTTTTTACATGTTTGGACTGCGGCCGGATTTTCCCAAGGAAGTCTACGTTCGAGCATCACTCGCAGATGCATTTAGTTCGAACGTGCCGGAGCTGCGATCGGCAGTTCACAAACAGAAGCTGCTACAGAGAGCATAGGACTCGGTGCGAGCCCAACGCCAAGCCGGACAAAAGCACCGTCCCGAGAAATAGACGATCGAACATTCGAGACCCAGCTGTCTTTATATGCGATTACTGCAGTAAGAAATACACGACGCGTCCGCAATTGAAGAACCACATACTATGGATCCACATGGACCATAGACCACACCAGTGTCAGTGGTGTGGAAAGAGGTTTTTCACGTTTGCAAGAATGGCTGAGCACTCTGTGGTGCACACTAGAGTGAGAAACTTTGAATGCGATATTTGTGGCGCGAAATTGGTTTCCAAAATGGCTGCCGTGTACCATAGACGACGTCATACTGGGGAAAAACCTTATAAATGCGAAGACTGCGATGCTACATTCATTTCTTCGTCGCGGAGACTTGAGCACGCTAAAAGGAAACATAATAAAGGTACAAAGATTCAGTGTCTGCTGTGTCCGAACAACTTTGTGAGGAGGAGTGAACTTAAAAAGCATATGGATAAAGTTCATAGTACTGTGGATGAGATGTAA
- Protein Sequence
- MKENSIEWAPSLPPRLCRACTSSISSFVPFYILCRESAFKWNQVATYLSTVTVNNQATTAYVLLGDDPQTVVDRSTSKNKAPKEVIKNVRTRLSVIRRTRQRIKAKIAPFRGRGSFYFFCPDCKKGPFDKLYKFNFHLNVNRKQCCPHCFKIICVTEFGDHLASHGLPSFECKVCNLHFDKETRLTKHKLFHYRGKYECSECKYTYTSMDRLTSHTNLVHAKTRCACDKLFFARTCYLGHKKRMCHKKPIQKFICDFCSKEFDRKFILRQHIQNFHSTPVYTEQCDQCGKRFKSKAHLKEHYYAHDKKLDRFTCEYCGKNYSTPRGHRRHLTKKHYQVDEESDLPPGLCRECTEDTLAAVAFRQLSQQSARYWHEATAYLTTIKDPTLKDKTFFVFYPQEKSVYNVTDPASTTESAVSVLNKPKTKRKRFSCHCLNCNKKFSCLENLNDHLKYTAQRFCYECGVGVDKKNLATHLSLRHGVEVLECKSCHEIFRNHVEVQRHWVKNHGPGTHSCSLCGAGFPHERGLRAHSYFHSLLHCPCGATFENARCHKHHIAKCKPQRHQTDSNFECDHCGVIYNKKPSLRMHMIQKHLNVLPFVCQTCGKRTSTLGHLRSHAQTHEPKRILLECHCGAKFRTDLGYKLHLRIHSGDKPYKCAQCKECFLSASRRLDHIKRRHQSSKDMPHCCTECNAKFIRPWELKKHYLNTHGSVIPEDDSCPIGACVGCASAALSAQEFRLFVRNSEKMWFKAISNLSNLESDQEERAKSICAFITPNDLTVLTAKDYIGGNAREVVNRSKTTVKKSKRRNRRQQIGPLISCPDCQKTFTSPFFLHEHLKNNGPRTACQMCGAVVTRGPELIEHMAVIHRETLITCPQCPCSLRSREDLNQHMKDAHRTGVFTCLDCGRIFPRKSTFEHHSQMHLVRTCRSCDRQFTNRSCYREHRTRCEPNAKPDKSTVPRNRRSNIRDPAVFICDYCSKKYTTRPQLKNHILWIHMDHRPHQCQWCGKRFFTFARMAEHSVVHTRVRNFECDICGAKLVSKMAAVYHRRRHTGEKPYKCEDCDATFISSSRRLEHAKRKHNKGTKIQCLLCPNNFVRRSELKKHMDKVHSTVDEM
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -