Basic Information

Insect: Episyrphus balteatus
Gene Symbol: ZFX
Assembly: GCA_026256485.1
Location: JAGTYB010000151.1:183967-192973[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.00028 0.033 15.4 0.2 1 23 202 224 202 224 0.98

2 16 0.46 55 5.3 1.0 1 23 268 291 268 291 0.87

3 16 0.024 2.8 9.4 3.0 1 23 423 445 423 446 0.96

4 16 2.2e-07 2.6e-05 25.2 2.9 1 23 452 474 452 474 0.96

5 16 0.00075 0.09 14.1 2.6 1 23 480 502 480 502 0.97

6 16 8.5e-07 0.0001 23.4 1.5 1 23 508 530 508 530 0.98

7 16 0.00016 0.019 16.2 4.3 1 23 536 558 536 558 0.98

8 16 3 3.6e+02 2.8 1.4 1 23 605 628 605 628 0.87

9 16 0.35 41 5.7 6.7 1 23 748 771 748 771 0.96

10 16 3.3e-06 0.00039 21.5 2.9 1 23 777 799 777 799 0.96

11 16 0.00059 0.071 14.4 3.0 1 23 805 827 805 827 0.97

12 16 6.1e-06 0.00073 20.7 0.6 1 23 833 855 833 855 0.98

13 16 1.5e-05 0.0019 19.4 1.0 1 23 861 883 861 883 0.98

14 16 0.0077 0.93 10.9 5.4 1 20 889 908 889 911 0.95

15 16 3.7e-05 0.0044 18.2 3.3 1 23 917 939 917 939 0.96

16 16 0.012 1.5 10.2 2.1 1 23 945 967 945 967 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.00028	0.033	15.4	0.2	1	23	202	224	202	224	0.98
2	16	0.46	55	5.3	1.0	1	23	268	291	268	291	0.87
3	16	0.024	2.8	9.4	3.0	1	23	423	445	423	446	0.96
4	16	2.2e-07	2.6e-05	25.2	2.9	1	23	452	474	452	474	0.96
5	16	0.00075	0.09	14.1	2.6	1	23	480	502	480	502	0.97
6	16	8.5e-07	0.0001	23.4	1.5	1	23	508	530	508	530	0.98
7	16	0.00016	0.019	16.2	4.3	1	23	536	558	536	558	0.98
8	16	3	3.6e+02	2.8	1.4	1	23	605	628	605	628	0.87
9	16	0.35	41	5.7	6.7	1	23	748	771	748	771	0.96
10	16	3.3e-06	0.00039	21.5	2.9	1	23	777	799	777	799	0.96
11	16	0.00059	0.071	14.4	3.0	1	23	805	827	805	827	0.97
12	16	6.1e-06	0.00073	20.7	0.6	1	23	833	855	833	855	0.98
13	16	1.5e-05	0.0019	19.4	1.0	1	23	861	883	861	883	0.98
14	16	0.0077	0.93	10.9	5.4	1	20	889	908	889	911	0.95
15	16	3.7e-05	0.0044	18.2	3.3	1	23	917	939	917	939	0.96
16	16	0.012	1.5	10.2	2.1	1	23	945	967	945	967	0.97

Sequence Information

Coding Sequence: ATGACTGAAGTACTATCACATACTTTTAAGCATGAAACAATAACCAGTATAAATAATCCAACAAAAGATCTCGAAACAAAATGTGGAGACATTCTCTTACTAGCCAATACAAATTTTGATGAACATATTCCAGAAGTTAAAGTTGAACCCTTACAAGATGCTCCAACAACAACTAACTTAGTTGTAGACAACGACGACGATGAGGATGATAAAAGTTCAATAGATTTAGATGCAGATATTGCTTCTCAAAATTCCGAAGATGAAAGTAACGAAGATGAAAAAAAGGATATTAAAGATGATCTTGAACCTGAAGTTAAAGTAGATATTGAAACAGAAGTTAAACCGAAAGATGATGAAAGTATTAAACAAATTGAAGAAGTTCTTACTAAAGAAATCAAGGTTCCACGAAGAAGAGGACGCAAAAAAGCACTCTACGAACCATTGATATCGATTTCGTCAAAAGACAAAAATGAGACTGAAAGTTCAGATAACAAGAACAATGAAGAAGCTCCAAATGAAACCTCAGAGACTAAAACTGAGGAAAACGATGATAGTTCACCAGACAAAAAAGGTAAGAAAAAATACTATCGCAAGAAAAATGTATTCCCCTGTCCGATTTGTAAAGAAAACATAACAGATGGTAGATCTCTTAAGAAACATATTCGATCGCACAATGAAGGAGGCAACGAAAACCGTTTCCAATGTGAGGAATGCGAAAATAACCTGATTGATGGCAAATATTCAAATTTTAAAGAAAGAAAATGTGGAGAAGTTATTTTACTGGCTAACATTGAATTTTGGTTTGTATGCACATTTTGCGATGAACGATTCCATAATGTTGTAATATTTCAAAACCACATTGAGAATGAACATATTAAAAATAATGAATCCAAATCAAAAAACAATGATCTATTAGATTTGCCGAAAAATGAAGAAACAGTTCAAGATGTTCACACTAGCAACAGTTGTGTCAATTCAACGGAAGAAACCGATACAAAATACTGCAATGATGTCGAGGATATTAAAAATTTCACTTCTGACCAGTCTGATGAAATCGAAGATGACATTGCAAAACTCAAAAATAAGGTGACACATAAAAGTACAAAAGAACTTACAGAAAGAGCAGAAGAAACTCATTCTGATAGTTGCCAACAAATGAATGAAAATGAGAACTCAGCAAATGAGACATTAGCTTTCAAAGACAGAAAAGATTTACTTCTTCCATCAAAGAAAGTTCCTAAAAAACGGAACCGCAAAAAGAAAGTTTACTCTTGTTCTTTTTGCCAGCACATAGCCCGTAATAAAAATTCATTAGAAGCACATTTGCTATCACACCATGGAACCGGAACTAGACATCAATGCGAAGAGTGTGGCAAATGTTTTAGGAACGCATCGAATCTTAAATCTCATTTAGTCATTCATTCCGGTACTCGTCCTTATAAATGTGATTTTTGCGATTCTGGTTTCTCACACCCAAACAGTCTTCGAACCCACCGTTACATACACACTGGCGAACGGCCTCACAAATGTAAGCTGTGTGATAAGGGATTTGTATCGAGTAGTGGGCTGAAAATTCATATGCGAGAACATACCGGCGAAACTCCTTATGTGTGTCAATATTGTGAGAGGGGATTTGCCAATAAATGCCATTACAATAGACACATTATTAGTCACTCAAGTCGAAAAGCTTTCGAGTGTAAGGAATCTTTTCCAAATGAAGAAATCAATGAGGCATGGGAGGATTCCGAACAATCAAATGGCACAGAACAAAAATGTGGAGAAATTATTTTACTATCAAATAGAAAGTTTTGGTTTCTGTGCACATTTTGCAATGAACGTTTTCATAGCGTTGTAATATTCCAAAACCACATTAAAGGCATACATATCAGAGACTTGGACTCATCACATTCAAATGTAAAGTTCGAATCTGTCGAATTGAATGAATATGAAGGATACCATGACCAAGTTAATGATAATTCATGGAAGCACAATGAAAATGAAAAACAAGACTCAAGTGATGGTGAAAAAGTAAAGAACCTGGATAATAAAATTGAGGAAATATTTCTAAACAACCAATCTGACGGTATTGGTGAAATGGTTCAAACAAATTCTGATTGTAAGAATGTTGACAATGTAACCAAAAATGAGGATGAACAACCATCAAGAGTTTCTAAGGACATTAAAGATCCACTACCCACCACAAAGAAGGTTCCAAAAAAACGGAATCGCAAAAAGAAGGTACATACGTGTCCCTTTTGTGAGCACATAGCCTGTGATAATAGATCATTACAAAGGCATATACATTCATCTCATAACACCGGAACTCGACATCAATGCGAAGAGTGTGGCAAGTGTTTCAGAAGCGGGTCTAATTTAAAATCTCATTTAGTTATACATGCCGGAACACGTCCATTTAAATGTGATATTTGCAACGTTGGTTTTAGCCATTACAACAGTCTTAAGACACATCGTTTTATACACACAGGCGAGCGTCCTCACAAATGTCTGGAGTGTGATAGAGGATTCGTTTCGAGTAGCGGACTTAAAGCACATTTGCGAGAACATAGAGGCGAAATACAATTCGTTTGCGAAATTTGTGAGAGAGGATTCTATACTAAAACTTTGTACAAAAGACATATGATAAGTCATTCAGGACGGCGAGCTCACAAGTGTACAGAATGTGATAAGGCTTTTCTTCATAGAGAAACTCTTACAAAACATATGGCGTGCCATTCGAGTGAAAAACAATTTGCTTGCAATATTTGTTCAAAAAAATTTAGTCACAAAAAGAACTTGGTTCAGCATGAAAAACTGCATCAAAATACTAAACAGTATATTTGCAAGGTGTGTAATAAAGATTTTGCACAGTATGCAGGCTTATATTGTCATATGAAGTATCATAAAGATAAAAAGTAG
Protein Sequence: MTEVLSHTFKHETITSINNPTKDLETKCGDILLLANTNFDEHIPEVKVEPLQDAPTTTNLVVDNDDDEDDKSSIDLDADIASQNSEDESNEDEKKDIKDDLEPEVKVDIETEVKPKDDESIKQIEEVLTKEIKVPRRRGRKKALYEPLISISSKDKNETESSDNKNNEEAPNETSETKTEENDDSSPDKKGKKKYYRKKNVFPCPICKENITDGRSLKKHIRSHNEGGNENRFQCEECENNLIDGKYSNFKERKCGEVILLANIEFWFVCTFCDERFHNVVIFQNHIENEHIKNNESKSKNNDLLDLPKNEETVQDVHTSNSCVNSTEETDTKYCNDVEDIKNFTSDQSDEIEDDIAKLKNKVTHKSTKELTERAEETHSDSCQQMNENENSANETLAFKDRKDLLLPSKKVPKKRNRKKKVYSCSFCQHIARNKNSLEAHLLSHHGTGTRHQCEECGKCFRNASNLKSHLVIHSGTRPYKCDFCDSGFSHPNSLRTHRYIHTGERPHKCKLCDKGFVSSSGLKIHMREHTGETPYVCQYCERGFANKCHYNRHIISHSSRKAFECKESFPNEEINEAWEDSEQSNGTEQKCGEIILLSNRKFWFLCTFCNERFHSVVIFQNHIKGIHIRDLDSSHSNVKFESVELNEYEGYHDQVNDNSWKHNENEKQDSSDGEKVKNLDNKIEEIFLNNQSDGIGEMVQTNSDCKNVDNVTKNEDEQPSRVSKDIKDPLPTTKKVPKKRNRKKKVHTCPFCEHIACDNRSLQRHIHSSHNTGTRHQCEECGKCFRSGSNLKSHLVIHAGTRPFKCDICNVGFSHYNSLKTHRFIHTGERPHKCLECDRGFVSSSGLKAHLREHRGEIQFVCEICERGFYTKTLYKRHMISHSGRRAHKCTECDKAFLHRETLTKHMACHSSEKQFACNICSKKFSHKKNLVQHEKLHQNTKQYICKVCNKDFAQYAGLYCHMKYHKDKK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -