Basic Information

Insect: Epistrophe eligans
Gene Symbol: L
Assembly: GCA_951394125.1
Location: OX596031.1:35393461-35413243[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 6e-06 0.00055 20.7 1.7 1 23 248 270 248 270 0.98

2 16 0.5 46 5.3 5.8 1 23 276 298 276 298 0.98

3 16 2.6e-07 2.4e-05 25.0 3.1 1 23 304 326 304 326 0.99

4 16 1.2e-05 0.0011 19.8 0.3 1 23 332 354 332 354 0.98

5 16 6.5 6e+02 1.8 0.2 3 23 418 440 416 440 0.83

6 16 0.0041 0.38 11.8 0.4 2 23 457 479 456 479 0.97

7 16 0.022 2 9.5 1.4 1 23 562 584 562 584 0.97

8 16 0.00045 0.042 14.8 1.1 2 23 592 613 591 613 0.95

9 16 7.6e-05 0.0071 17.3 1.3 1 23 621 646 621 646 0.92

10 16 0.0016 0.14 13.1 2.9 1 23 738 760 738 761 0.96

11 16 0.0011 0.11 13.6 4.6 2 23 948 970 947 970 0.96

12 16 0.13 12 7.1 0.1 1 23 976 998 976 998 0.92

13 16 4.1 3.8e+02 2.4 0.3 2 23 1006 1027 1006 1027 0.92

14 16 7.5 7e+02 1.5 0.3 2 23 1118 1139 1118 1139 0.92

15 16 0.0095 0.88 10.7 0.0 1 23 1149 1171 1149 1171 0.96

16 16 2.5 2.3e+02 3.1 1.3 1 23 1178 1200 1178 1200 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	6e-06	0.00055	20.7	1.7	1	23	248	270	248	270	0.98
2	16	0.5	46	5.3	5.8	1	23	276	298	276	298	0.98
3	16	2.6e-07	2.4e-05	25.0	3.1	1	23	304	326	304	326	0.99
4	16	1.2e-05	0.0011	19.8	0.3	1	23	332	354	332	354	0.98
5	16	6.5	6e+02	1.8	0.2	3	23	418	440	416	440	0.83
6	16	0.0041	0.38	11.8	0.4	2	23	457	479	456	479	0.97
7	16	0.022	2	9.5	1.4	1	23	562	584	562	584	0.97
8	16	0.00045	0.042	14.8	1.1	2	23	592	613	591	613	0.95
9	16	7.6e-05	0.0071	17.3	1.3	1	23	621	646	621	646	0.92
10	16	0.0016	0.14	13.1	2.9	1	23	738	760	738	761	0.96
11	16	0.0011	0.11	13.6	4.6	2	23	948	970	947	970	0.96
12	16	0.13	12	7.1	0.1	1	23	976	998	976	998	0.92
13	16	4.1	3.8e+02	2.4	0.3	2	23	1006	1027	1006	1027	0.92
14	16	7.5	7e+02	1.5	0.3	2	23	1118	1139	1118	1139	0.92
15	16	0.0095	0.88	10.7	0.0	1	23	1149	1171	1149	1171	0.96
16	16	2.5	2.3e+02	3.1	1.3	1	23	1178	1200	1178	1200	0.92

Sequence Information

Coding Sequence: ATGATGGCATTAAAAATGCTCTATCGTGGACCAAGTTCAagattggaaaatttaattgaaaaaatacaagCTACCAAAGATGGAAATCCAGATCTGTACTCGACACACACCTCGTCCAGCTACTCGCCCTCCATGTCAGACGGGACAATTACTCCGAACTCGCTCCATcaccatcatcttcatcatcaccatcatcatcatcagcagcagcagcagaggCTGCACCatcacttgcagcagcaataccAATGTGAACAGCAACAGAATAGGGGcaacggtggtggtggtggtggtggcggtggtcACAACCGCGACAGGCATCACAATCGACGTGTTTCAACCTTAAATGGAGCAACTGCTACTGGTGTCACTGGTAGCGGCAACAACGAGGACGACGATGAGaatgatgacgacgatgatgggGCTGGTGACGGAGATGCAGACGAAGATGACGACGCCGCAAATTCTAGCGAAGAAAGGGTTTTCCTTACGTcaaatggtggtggtggtgccaATGATGCTGTTGGAACAAACACCACAACCACCACTTCAACCACCTCGAACAGCATCAGTGGCGCAaacagcggcggcggtggtggtggtggaggcaGTGGCGGTGGCGGTGACAAACATTCCGTGAAAATTCCAACGAAATTGCGGAAAATCGATAGGGATTCGGCAAAGTTGTTGGATAAGTTGACAAGTGATGGCATTAAGAGCGCGACCGACCGCGATGGATCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGCCTTGGGTATCTCAAGAAGCATGAACAGagtcaTGCCGAGCACCTACCATTCAAATGTGACTACTGTGCAAGACTTTTCAAACACAAACGGTCTCGTGACCGACACACTAAGTTGCATACTGGAGATAGACGATACAGGTGTCCACATTGTGAGGCGGCTTTTTCAAGAAGTGATCATCTGAAGATCCACATGAAAACCCACGACAACCAAAAGCCATTCCAATGCACCATCTGCAATCGAGGCTACAATACCGCCGCAGCACTAACATCGCACATGCAAAATCACAAGAAACAAGCCGCAATCCTTGCTGCTGGTGGCAATCCGGCTGCACTTAACTACAGCCCTCGATCAACTGGTTCCGGTTCCAGTAATGGCAGTTTGCAAAAACGCCGTTACACATCCATTGCAAACACCAAGAGTCCCAGTCCGAGTACATTGGAATATGCCAAGCGTATGCGCAGTTCCTATGTCTCATGCATGTATTGTACAAAATCCGATTTCGCATCAATGGACCAATTAAGCAGTCATATCCAAGCAATGCATGAGAAGGAAGCACTTGCCAATCAATCGGTGCAAAGTGGTTTTCAAATGTCCTGTGAGTATTGCACCATGAAGTTCCCCAGTGTTCCGGCAATGTTCCAACACATGCGAACGACACATATTGATCGTCTTTCAAGCCCCAGTAGTTATTTCGAACATTTTAATCGATTGGCTGCAACTGGGACTTTCAGTCCTCGGCTGCAAACCCCAAAGTCGAATGAAACAAAGGTCAAAGTCGAAGAACCAAGTCCTAAGGGTGAAGAAAAAACAACTGACGACGAACCAACTGATTTAAGTCAAAACCGCGGACGATCCATTCATACTCCATCCCAAGAATCGGCCGAAGCTAATGACAGGCCGGGTGTGTTCTTCTGCAACCAGTGCAACGATGGTTTCCCCGATTTCGATAGCTTCCGCAATCACCTTAAGTCGCATATTGTTCAGGGACTCAGTTTGGTTTGTCATCATTGCGGCCAGACCTTGCGAGATCAACCAGAGTATGAAAGGCATATTGTTTCACATTTTCTAATCACTTGCTCGGAATATTCATGCACCGAAAAGAACTGCAATAAGACCTTCTCCAAACCGGACGAGCTGCAGAAGCACCTCTTCGAAAACCACATTCAGACGTTGTTCAAGTGTCTGCTGTGTTCGGACTTGTTCGAAACAAAAGTTGCCGTGCAAGTTCACTTCGCTTGCATTCATTCCCCGGAGAAGAAGATTTTCCGTTGTTCAGCCTGCATGGACACCTTCCATGGGGAACAAGAATTCCATATTCATGTGAAAACTCGACATCAGACCATAGTTGGTTCTCCAATTCAATGCATGTTCTGCCGAGCTGTCTGTTCTACCGAACTGGAAATGCACTTCCATCTGGCGGCTCATGCTCGTCAGTTCCGTTGTCCGTCATGTCCAGAGACGTTCCATGTCGAATTCCTACTCGATCGACACATGCAAACCCACCATCATGGACAAAAAGAAGTTGATTCCACCCCATCTCCTGCTGTGAATCCATGTCCAGTGAACTCGATCAATCCCCTGTACATGAGTGCTCTCTTCAATAAGCCTCCCCCATCAactcaaaacaacaacaacagcatccTGGATTACAACGCTTTCGCAATGGGCAAGAATCTCTTTGGCAATGCTTCGGGGAACAAATTCTACAATCCTCTTCAAGTCGATACGGGATCGGCAATGAAACATCCATCACTTGTCTATGCCAGCTTGAATCAACGCTACTTTGACACCAATCGAACTATCTTGGAAATGTACAATCAACATCAGCAGGATAAAATTGCAGCTGGCCCCATGTTCACAAGTCCcagcatcaacaacaataacaacaataactcCAGAAACCCACCAAAACTTTCCCAAGAATCCAACAAACCCTCAGATCGATCTATTCCTGCCGGAGGCGGTTTCAGCTGTGGAATGTGTGAACGCAATGATTTTCGCACCGAAGCCGAAATTCACTCCCACCGCAAGATCGTACATAATCTCAAGACCGGAGTGAGTCTTCGATGTGCTTATTGCAGTGGAAACTTTAAGTCACGCAGTGAACTGGAACATCACATGAAGACGTGTCACAATTCAACTGGCAAACACAAGTGTTTGATTTGCGATGAAATCTTCCCATCGCCCGCAATACTCGCCGAACATAAGTTGCAACACTCAAAGGTCGGACAGTCGGGAAAGTGTTCCCACTGCGCTAAAGCTTTGCCCGATGTAATGGCGTTTAAGGGACACCTGCTGGATCACAACACCGAGGGACAAATGCCAGTTCAGTGCATTTGCTGTCGCCAAACATTACATTCAGATTTTGAAATTGGTCTCCATGCCAAattCCACACAAAGTCATCGTCTGTTTCGGAGAGCGTTTGTGCACTGTGCTTGGAAACAATACCCAACACAATCGATGCCAAGGTTTGCGACAAGTGCTGCCGCAAGCATAATCTCAACAACAAGTACTCAAACCAGCGAAGCAGCTTCGACAGCAATTCGGGACAATCGTCAAACTACGTGGAGAATCGTTGTAATCTCTGCAATGTCATCATGCCCCACGCCCAGAAACTCCAAGAACACTTGGTGGAACACACATTCGCCGGCTGCGAAGACAGAGGCTTCTCGTGCTACATATGTTCGGCAGTCTTTACAGCCCCTGCTGGCTTGCTCACTCACATGACCGAACACGGAGCTAATTCCCGTCCCTACGATTGCAACCTTTGTACTGACAAGTTCTATTTCCGCGCCGAACTGGATCATCATTTGGTCGATCACGAAACTCGAGATCGATCAAAGTCCTCCCATGCCAGGGATGTAAGTCCTCCAACCGATGACAACAAGACTTCATTCACCGAACCATCAACACCGTCAGCAGAAACAGAATCTAAGAAGCTTGAACTTAAAAATGAAGTCCTCGAAGACAAACCAACCGAAGAAGATGACGATGAATACATTGAAGTTGAGAAAGTTCCCGAAATTATTACATCGCAGGAGAAATCATCGCGTCGTCCTTCAGACAAGGATGAATAG
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKDGNPDLYSTHTSSSYSPSMSDGTITPNSLHHHHLHHHHHHHQQQQQRLHHHLQQQYQCEQQQNRGNGGGGGGGGGHNRDRHHNRRVSTLNGATATGVTGSGNNEDDDENDDDDDGAGDGDADEDDDAANSSEERVFLTSNGGGGANDAVGTNTTTTTSTTSNSISGANSGGGGGGGGSGGGGDKHSVKIPTKLRKIDRDSAKLLDKLTSDGIKSATDRDGSYQCQFCDKSFPRLGYLKKHEQSHAEHLPFKCDYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQAAILAAGGNPAALNYSPRSTGSGSSNGSLQKRRYTSIANTKSPSPSTLEYAKRMRSSYVSCMYCTKSDFASMDQLSSHIQAMHEKEALANQSVQSGFQMSCEYCTMKFPSVPAMFQHMRTTHIDRLSSPSSYFEHFNRLAATGTFSPRLQTPKSNETKVKVEEPSPKGEEKTTDDEPTDLSQNRGRSIHTPSQESAEANDRPGVFFCNQCNDGFPDFDSFRNHLKSHIVQGLSLVCHHCGQTLRDQPEYERHIVSHFLITCSEYSCTEKNCNKTFSKPDELQKHLFENHIQTLFKCLLCSDLFETKVAVQVHFACIHSPEKKIFRCSACMDTFHGEQEFHIHVKTRHQTIVGSPIQCMFCRAVCSTELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQTHHHGQKEVDSTPSPAVNPCPVNSINPLYMSALFNKPPPSTQNNNNSILDYNAFAMGKNLFGNASGNKFYNPLQVDTGSAMKHPSLVYASLNQRYFDTNRTILEMYNQHQQDKIAAGPMFTSPSINNNNNNNSRNPPKLSQESNKPSDRSIPAGGGFSCGMCERNDFRTEAEIHSHRKIVHNLKTGVSLRCAYCSGNFKSRSELEHHMKTCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCSHCAKALPDVMAFKGHLLDHNTEGQMPVQCICCRQTLHSDFEIGLHAKFHTKSSSVSESVCALCLETIPNTIDAKVCDKCCRKHNLNNKYSNQRSSFDSNSGQSSNYVENRCNLCNVIMPHAQKLQEHLVEHTFAGCEDRGFSCYICSAVFTAPAGLLTHMTEHGANSRPYDCNLCTDKFYFRAELDHHLVDHETRDRSKSSHARDVSPPTDDNKTSFTEPSTPSAETESKKLELKNEVLEDKPTEEDDDEYIEVEKVPEIITSQEKSSRRPSDKDE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01542500;
90% Identity: iTF_00427670;
80% Identity: -