Basic Information

Insect: Epistrophe eligans
Gene Symbol: Clamp
Assembly: GCA_951394125.1
Location: OX596031.1:51152147-51154449[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 2.3e-05 0.0021 18.9 3.7 1 23 127 149 127 149 0.99

2 7 8e-06 0.00074 20.3 1.0 1 23 386 408 386 408 0.98

3 7 4.8e-06 0.00044 21.1 0.1 1 23 414 436 414 436 0.99

4 7 3.2e-06 0.0003 21.6 3.2 1 23 442 464 442 464 0.99

5 7 1.8e-06 0.00017 22.4 0.4 1 23 470 492 470 492 0.98

6 7 1.6e-06 0.00015 22.6 0.4 1 23 498 520 498 520 0.98

7 7 9e-05 0.0084 17.0 0.2 1 23 526 548 526 548 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	2.3e-05	0.0021	18.9	3.7	1	23	127	149	127	149	0.99
2	7	8e-06	0.00074	20.3	1.0	1	23	386	408	386	408	0.98
3	7	4.8e-06	0.00044	21.1	0.1	1	23	414	436	414	436	0.99
4	7	3.2e-06	0.0003	21.6	3.2	1	23	442	464	442	464	0.99
5	7	1.8e-06	0.00017	22.4	0.4	1	23	470	492	470	492	0.98
6	7	1.6e-06	0.00015	22.6	0.4	1	23	498	520	498	520	0.98
7	7	9e-05	0.0084	17.0	0.2	1	23	526	548	526	548	0.96

Sequence Information

Coding Sequence: ATGGAAGACATAACCAAAACAATAATGTTCACAACAAATACTATACAAAATGGTCAGCCAACAATTCAGTACCAAACGGCAGatggaacaattttaaaacaaccaAAAATAGAGGGTCAAAAAAGTCAGCAAGATTATCCAACATTTTGTTACACTACCACAAATGGTAACGCGACAACTGTTAATTTAGCCCAACTAACTACTGACGATAATAAAACATGTTATATCGCCCAACCAATTGGTGGTTACAACTATGCTTTGGTAAACCAAATGCAACTTAACCAAGGGGGTACTGTTGGAATCGCCACTGTTGATAATCAAGGTCGTTtacaagttataaataaacccATCGCAGccAACACAATATCGAATATTAGTTTCAAATGCGATGTTTGCGGTCTTATGTTTTCTCATTTGACTTTACTGAATCATCACAAACGCATTCATGCTCAAGATGGCAGTGATACAAATCAGGATCAGATCGCTGTAGTTAATGCACAGGGACTTGTGCAAACCCAGAATATAATAACCGAAAATGGACAACCCCTAGGCCAGATACAAATTGTTGCCACTGAATCATTAGAACCCGCTAGCTCACATTCCATGCAGCAAACGGCAAACGAGGTAACGGTTACCACAGCTAAAACGTTGACTCTAGAAAAATCCAAATGTATATCATGTGGTGGACAAATCCTTCAGCCTACAAAAAGAAAAGGCCCGAAGATAGTGCGTTGTGATAATTGTGCTAACAACGATAATGGAAATGGCAATATGCAAACACAAACGTCACAGGCGACACCCACACAAATATTTGTTGCTCCTGATGgagaaataaaattcgaaatgaATGAAATTCCGAGTGGAACGAGTGAATCATCAATGGATTCACTGAATGCACAAAACATTATTCCAATGCAACAAGGGAATGGAGGCAATTCATCGAATAGTGGTAGGAAAATTCAACATCAGCAGCATCAACATCAACAGCAGGAAATAATAACTGATAATAGTGGATGTAATGAAACAATTGTTGGTCATCATCCAGTTAAAAAGAGAAATCTTGCAACAGTCACCAAGTGTCAAAAGTGCAATGGATCGGGAGTGATATTTGTAGGCGGCAGTCAAAGACAAGTCAAATCAGAaacccCCAAACCCTTTACTTGCAATATCTGCGGCGGGACATTTTCTAGGTATTCCAGTTTATGGTCCCATAAAAAGTTACACAGCGgggaaaaaaactataaatgtaCAATCTGCGGTTTGGCGTTTGCAAAAGCggtttatttgaaaaatcacGCTAGAATTCATACTGGTGAAAAGCCTTACAAatGCCAGACATGCGGAATGCAATTCTCTCAATCACCTCATCTTAAAAATCACGAACGAACTCACAGCGGCGAAAAGCCGTATGTTTGCGAAGTCTGCGATAAAGGATTTGCCCGCCATGCAACTTTATGGAATCATCGTAGAATCCATACCGGAGAAAAACCATACAAATGTGACATCTGTGGATCAGCATTCAGTCAAGCAGCCCACCTTAAAAATCACGCCAAGGTTCATTCCGGTGAGAAACCATTTAAATGTGATATCTGTTCAGCAGCGTTTGCTGATCGCTTTGCGCTTAAGCGACACCGAGGAATTCACGAGAAATATggtcaaaCAGCACCTCGGCATTCATCTCAATTACAAAATCATGACGAACAAGTTCAGATAACACAATCAATGGTTATCCACAAACAAGAAATGCCCGAAATGGACGATGAAGCCCAGCACGAAGTCATAATAGCAGGATTATAA
Protein Sequence: MEDITKTIMFTTNTIQNGQPTIQYQTADGTILKQPKIEGQKSQQDYPTFCYTTTNGNATTVNLAQLTTDDNKTCYIAQPIGGYNYALVNQMQLNQGGTVGIATVDNQGRLQVINKPIAANTISNISFKCDVCGLMFSHLTLLNHHKRIHAQDGSDTNQDQIAVVNAQGLVQTQNIITENGQPLGQIQIVATESLEPASSHSMQQTANEVTVTTAKTLTLEKSKCISCGGQILQPTKRKGPKIVRCDNCANNDNGNGNMQTQTSQATPTQIFVAPDGEIKFEMNEIPSGTSESSMDSLNAQNIIPMQQGNGGNSSNSGRKIQHQQHQHQQQEIITDNSGCNETIVGHHPVKKRNLATVTKCQKCNGSGVIFVGGSQRQVKSETPKPFTCNICGGTFSRYSSLWSHKKLHSGEKNYKCTICGLAFAKAVYLKNHARIHTGEKPYKCQTCGMQFSQSPHLKNHERTHSGEKPYVCEVCDKGFARHATLWNHRRIHTGEKPYKCDICGSAFSQAAHLKNHAKVHSGEKPFKCDICSAAFADRFALKRHRGIHEKYGQTAPRHSSQLQNHDEQVQITQSMVIHKQEMPEMDDEAQHEVIIAGL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00672376;
90% Identity: iTF_00724993;
80% Identity: -