Eeli010540.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Epistrophe eligans
Gene Symbol
Prdm14
Assembly
GCA_951394125.1
Location
OX596029.1:63507680-63509202[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.025 2.3 9.3 2.5 1 23 227 249 227 249 0.97
2 9 3.1e-06 0.00028 21.7 1.0 1 22 255 276 255 278 0.91
3 9 0.00028 0.026 15.5 3.2 1 23 285 310 285 310 0.94
4 9 2e-06 0.00018 22.3 0.9 1 23 320 342 320 342 0.97
5 9 1.3e-05 0.0012 19.7 1.5 1 23 349 371 349 371 0.99
6 9 6.6e-05 0.0062 17.5 0.5 1 23 377 399 377 399 0.97
7 9 0.00019 0.017 16.0 0.0 2 23 406 428 405 428 0.95
8 9 3.9e-05 0.0036 18.2 3.4 1 23 434 456 434 456 0.98
9 9 5.8e-06 0.00053 20.8 1.0 1 23 462 484 462 484 0.98

Sequence Information

Coding Sequence
atggaCATAACTCTGGACAACATTGATTCGCTTTGTCGCACCTGCCTGGAAGTGATGGAACCCGGTTCGGAAATAAATATTCACAATACTCCAAACGTAGCGAAGTGGCTTGTTGTCTGTACCTCTTTAGATTTTGAACAAGATGATGGTTTTCCAAGTCAAATATGTCATACTTGCTATACCAAAATACAAACTTCCTACGAGTTCCGTGTAATGTGCATCAAATCGTTTCGTGAGTTAGACGGtgttataaattcattttccaAACTCGAAATCCATAGAATCGAGTTGGAAGACGCTTCGGGTAGTTTAAGTAGTATACAATGGTTACAACTGGCGAATAAATTAGAAGTCAATGAAGATGAAGAATTGCTTGTTGAGCACAAAAGAGAGAATTCTCCAACACAAACAGATGAAATTAAAGTTGGAAACTCTTCCGCTGAACCTCCAAAAGCCTTACCGAAGGCAGTTCTCGAGGAACAGGAAATTGACCACGATGTTTTTAGTGGTTTCGTTGACGATTCTACGGACTACGACTCTACGCCCGAACAAAATATTCTAGACGGGGTAGAAGAGAGTgcagaaaagaaaaatacgaAACCACCTCCAGCACGCAGAGGTAGAAAGCCCAAAGATGAAGACTATACCATGCCTGCTTATATTAAGACCCCTGAAATATACAATTGTGAAAAATGCCTAAAGAAGTTCTTCAAAAAAGACCGGTTTGATGCACACGTTCGGCTGCACAAGGGCCTTAAGCCATATCCATGCACACTTTGTGATAAATCCTATAACAAATCTTCTCACTTGAAGGTTCATATGGGAGATGTACACACCGAACACAAGGAGGACTTTAAATGTGAATATGAAGGTTGTGATAAAGTATTCCGTCGCAGACAAACGCTCCGAGTGCACTGCCGGATAAAGCACTCGGAGGTTAAGTACGAACCAAAGATCTTCATATGTGAAGAATGTGGCAAGACTTTTAAGAACATCAGTGCCCTCAAAGAGCATCGGTTTAAGCATACGGGCGAAGAATATCCATACAAGTGTGATCAATGTGGCAAGGGATACGTATCACAGCGAACATATAGAGATCACCAGATGCGACATGCTGggatcaaaaactttgtttgtcCGTATTGCGGCCTTCGGAAAACTACGAAGAGTGAACTGCGTATTCATATTAATTATCACACCAAGGAAAAGCAGTGGCCCTGCCCGGAGTGTCCCCAAGTATTCAACAGTTCTGCTAATCTCGGCTTACACAATCGAATTGTTCACAAGGGAATACGGCGGTTCAAGTGCAAATACTGTGATCAGAGCTTTGGTAAAGCCGAAACTCTCAAGCATCATGAAATGCGGCACACAGGCGAAAAGCCACACGAGTGTAATATATGTAAGAAACGATTCATCCAAGTGGTCGCGCTGCGAGCTCATTTGAAAACGCACAACAAAGCGACttga
Protein Sequence
MDITLDNIDSLCRTCLEVMEPGSEINIHNTPNVAKWLVVCTSLDFEQDDGFPSQICHTCYTKIQTSYEFRVMCIKSFRELDGVINSFSKLEIHRIELEDASGSLSSIQWLQLANKLEVNEDEELLVEHKRENSPTQTDEIKVGNSSAEPPKALPKAVLEEQEIDHDVFSGFVDDSTDYDSTPEQNILDGVEESAEKKNTKPPPARRGRKPKDEDYTMPAYIKTPEIYNCEKCLKKFFKKDRFDAHVRLHKGLKPYPCTLCDKSYNKSSHLKVHMGDVHTEHKEDFKCEYEGCDKVFRRRQTLRVHCRIKHSEVKYEPKIFICEECGKTFKNISALKEHRFKHTGEEYPYKCDQCGKGYVSQRTYRDHQMRHAGIKNFVCPYCGLRKTTKSELRIHINYHTKEKQWPCPECPQVFNSSANLGLHNRIVHKGIRRFKCKYCDQSFGKAETLKHHEMRHTGEKPHECNICKKRFIQVVALRAHLKTHNKAT