Basic Information

Gene Symbol
-
Assembly
GCA_951394285.1
Location
OX596164.1:4042742-4046012[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 23 9 6e+02 1.7 4.7 2 20 12 30 11 32 0.92
2 23 0.00046 0.031 15.2 4.2 1 23 79 102 79 102 0.97
3 23 0.13 8.5 7.5 0.2 2 23 131 153 130 153 0.94
4 23 0.0096 0.64 11.0 0.9 1 23 174 197 174 197 0.94
5 23 0.00076 0.051 14.5 1.3 1 23 202 225 202 225 0.93
6 23 3.9e-05 0.0026 18.6 0.2 1 23 230 253 230 253 0.94
7 23 0.0051 0.34 11.9 2.9 3 23 260 281 258 281 0.96
8 23 0.00022 0.015 16.2 2.9 1 23 285 308 285 308 0.98
9 23 0.034 2.3 9.3 1.2 2 23 315 336 314 336 0.97
10 23 4.3 2.9e+02 2.7 0.0 3 23 341 362 339 362 0.84
11 23 0.0046 0.31 12.1 0.4 1 23 381 403 381 403 0.97
12 23 0.00042 0.028 15.3 8.0 1 23 408 430 408 431 0.95
13 23 0.024 1.6 9.8 5.7 1 23 436 459 436 459 0.94
14 23 0.16 11 7.2 3.4 2 23 462 484 461 484 0.93
15 23 8.8 5.9e+02 1.7 0.2 2 20 491 509 490 511 0.91
16 23 0.02 1.4 10.0 1.8 1 23 566 589 566 589 0.97
17 23 0.0027 0.18 12.8 0.5 2 23 664 686 663 686 0.95
18 23 4e-05 0.0027 18.5 0.5 3 23 693 714 691 714 0.95
19 23 0.00022 0.014 16.2 1.7 2 23 719 741 719 741 0.96
20 23 0.0024 0.16 12.9 0.3 1 23 746 769 746 769 0.97
21 23 0.002 0.14 13.2 6.2 1 23 773 796 773 796 0.97
22 23 0.033 2.2 9.4 1.9 3 23 804 824 803 824 0.96
23 23 3.4e-06 0.00023 21.9 1.3 1 23 830 852 830 852 0.99

Sequence Information

Coding Sequence
ATGAAGAAGGAACACCAACTACACGCTGGTGGAAAGTGTGGTTTCTGTTGCAAGCAGTTTAGTACGAAACATAGTTTCTTAGATCACACTACTAGATGTAATGTTTCTCCGAAAGACGAGTTGATCACCGTCGATGATACTGATAAAAGCAAGAACGTGCAAGATCTGAGAACCGGTATTGCGTATATCATAAACATGACCACTGCTATGCCTTTTAAGTTCTTCCACAGCAAGTTTAGATGCTTTTACTGCCCCAAAGACTTCACGACCTGCAATGATCTTAAAGACCATACAACAACTGATCATCCTATTTGCGAAACCACATTTCACTCGATGAAACTTCGAGGCAGATCGGATGGagtcaaaataaaagttgatACGTCTTCTCTATATTGCAAAATATGCCCTAAAAAGCTCACAGATTTCATTACAGCTATCAATCATTTAGAAACAGAACACAAAGCTGTTGTTAGCAAATGCGTTGATATGTTCAGACCCTTCAATTTGGTGCATGATAAGTTTGTCTGTTCATTCTGTAGTACCGAGTTTCGATATTTCAGTTTGTTACTACAACATGTTAATGCGAATCATTCAGATAGCGAATATATTTGCACTTTCTGCGGTAAAGCCTTCCCGTCTTATCCCAATCTACGTGGCCATACCTCGCACTACCATTCCAGTGGTAGATTTAAATGTAAAGAATGCGACCTAGGCTTTCCTACAAATGATGCTTTGAAATTACACATGGGTAATACCCACGGTAGTAAAGTGATAAACTGCCAACAGTGTTCGGAAAAGTTCGTCTCTCGGTACCACAAAATGAGGCATATGATGAAAGTTCACGATGCTGGCCATAAATGCTCATATTGTGGTATGGCTTTTATCAAATACTCGTTTATGACGAATCATATAAGGCGACTGCATCTCAAAGAGAAGAATGTTCAGTGCACGCTCTGTACTGAGCGATTCTTTGATACAAATCGCTTAAAGTTGCACATGGTTAGGCATGTGGAAATTGCGTGCGAGCGATGCGAGCAAGAATTCAAAACTCTTGAAGTTATTGTTGAACATCTGATAAACGAACATGGGTTGTTCTATGACAAAGAGTCTAGTGACATCGTAGAATACAGATTGATTGATTTCCGATGCACGCAGTGTGACGCACAGTTCGAAACATTTAGAGATTTGGATGTTCACATCAACGATCACCGGCAAAACAGTTTTGTCTGTCATCATTGCGAACGTATATTCACCAGAAAGAGTGATATCAGATCTCATATGTTTAAGCACCATCGATATGGAGGGTTCACTTGTAAACAATGTGGTATAGAATGTAAAAGTCGATTCAAATTACGGAAACATACAGAACACGCTCATATGACGCGATGCCATGTTTGTGGTGAGATATTTATGCACCTAAATAAAATGCTCAAGCACTTTAAACTGGAACATCCGAATGACAATAATAAAACCTGCGGGTACTGCTTAATAAATTTCCAAACTATGCTCGGTTTAAAACAACATTTGGTGAAATGTAAAGTGAGATTACCCTTGCTATACAAAACTGAAAATGTAGTCATAGGCAGCAAAAATACTAATACTTCAAGAACGCACGAACAAATAGTCCGTATCCGTGAAAACATTCAATGCGTTTTAAATATGTCCACCGCTGTACCATTCCGGTTTAGAGTCAAGTTCTCTTGCTTCTACTGCTCTCAGAAGTACGATGATTATGAAGTGCTCAAACAGCATACACGTTCCGAGCATCCTAAATGTGATATCAAGAGCAAATGCATGAAGACTTGTAAAGGGAAACGCACGTTTGTCAGGGTAGATATTGCAGATCTCGCTTGCAAACTTTGTTCCGCGTCTATGCCAGATCTGGAGCATTTTATAGACCATGCGATAGCTAACCATGATGCGGACTACGATAAGTCAGTCAGCATCGAAACTTGCTTTGAGCCGTATCGTCTCGTCAAAGGCAACATCCAATGTCTCGAATGCCCGAAAGTGTTCCGATATCTAAACACGATGCTGAGGCATTTCAATTCGGATCACAGCAATAATAATGTGATTTGCGATTACTGTGGCCGCGGATTCCGGAGCACGACCAATCTAAAGATGCATCTGCAGAACACACACACTGGATCTGCGGAATGCAAGTTCTGCAAttataagtttaaaaacaGATCTGTACTTGTCCGCCACATGGCGAAAAGCCATAATGAGATGACTTTCAAATGCCCCACCTGCTCGGAAATGTTTGCGTCTGCGTACAAACGCCAGATCCACCTAATCAAAGTCCACGGTATAGGACATAAATGTGAATATTGCGGGAAGATGTTCACAAAACACTCGTTTATGGATTCCCACGTCAGACGCACACATTTGAAGGAAAAGAACGTAGCTTGCTCGATTTGCAACGATAAGTTCTTTGACAATCATCTGCTAAAGATGCATATGGTTAAACATGATGGTGAGAGGAAGTTTAAGTGTGAGTTGTGCGGCAAAGCGTTTTTGAGGCAGAAGAATTTACGGACTCATATGGAcactcataaaaaatatggcTTTGTGCAATGA
Protein Sequence
MKKEHQLHAGGKCGFCCKQFSTKHSFLDHTTRCNVSPKDELITVDDTDKSKNVQDLRTGIAYIINMTTAMPFKFFHSKFRCFYCPKDFTTCNDLKDHTTTDHPICETTFHSMKLRGRSDGVKIKVDTSSLYCKICPKKLTDFITAINHLETEHKAVVSKCVDMFRPFNLVHDKFVCSFCSTEFRYFSLLLQHVNANHSDSEYICTFCGKAFPSYPNLRGHTSHYHSSGRFKCKECDLGFPTNDALKLHMGNTHGSKVINCQQCSEKFVSRYHKMRHMMKVHDAGHKCSYCGMAFIKYSFMTNHIRRLHLKEKNVQCTLCTERFFDTNRLKLHMVRHVEIACERCEQEFKTLEVIVEHLINEHGLFYDKESSDIVEYRLIDFRCTQCDAQFETFRDLDVHINDHRQNSFVCHHCERIFTRKSDIRSHMFKHHRYGGFTCKQCGIECKSRFKLRKHTEHAHMTRCHVCGEIFMHLNKMLKHFKLEHPNDNNKTCGYCLINFQTMLGLKQHLVKCKVRLPLLYKTENVVIGSKNTNTSRTHEQIVRIRENIQCVLNMSTAVPFRFRVKFSCFYCSQKYDDYEVLKQHTRSEHPKCDIKSKCMKTCKGKRTFVRVDIADLACKLCSASMPDLEHFIDHAIANHDADYDKSVSIETCFEPYRLVKGNIQCLECPKVFRYLNTMLRHFNSDHSNNNVICDYCGRGFRSTTNLKMHLQNTHTGSAECKFCNYKFKNRSVLVRHMAKSHNEMTFKCPTCSEMFASAYKRQIHLIKVHGIGHKCEYCGKMFTKHSFMDSHVRRTHLKEKNVACSICNDKFFDNHLLKMHMVKHDGERKFKCELCGKAFLRQKNLRTHMDTHKKYGFVQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-