Basic Information

Gene Symbol
-
Assembly
GCA_963565295.1
Location
OY751403.1:3836538-3853115[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 3.9 2.6e+02 3.0 2.1 1 23 203 225 203 225 0.86
2 13 0.36 24 6.2 0.0 2 23 316 338 316 338 0.92
3 13 5.3 3.6e+02 2.5 1.0 1 23 433 459 433 459 0.92
4 13 4.6 3.1e+02 2.7 1.3 1 19 800 817 800 820 0.75
5 13 0.17 12 7.2 2.1 1 23 832 854 832 854 0.94
6 13 0.0032 0.21 12.7 0.3 2 23 860 881 859 881 0.97
7 13 0.044 2.9 9.1 1.5 2 23 993 1014 992 1014 0.94
8 13 0.00081 0.054 14.5 2.9 1 23 1029 1051 1029 1051 0.98
9 13 3.5e-07 2.3e-05 25.1 2.2 1 23 1057 1079 1057 1079 0.98
10 13 0.0003 0.02 15.9 2.3 2 23 1085 1106 1084 1106 0.95
11 13 0.022 1.5 10.0 4.2 1 23 1112 1135 1112 1135 0.96
12 13 2.3 1.5e+02 3.7 0.3 1 13 1138 1150 1138 1156 0.83
13 13 0.0002 0.014 16.4 0.2 3 23 1170 1191 1169 1191 0.95

Sequence Information

Coding Sequence
ATGTCCGAAGGCAGGAAAAGAAGTCGTAAATCTAAGTTGGAAGTTCGTGCTTCTGATGAATACGAAGTTGTGAACGAGCAGAGTGACGAAACAAGTCCGCCTTTGCAGAAAGTATCAAGAACAAGGCTTCAGGTGGAGTATCCAGATGTTCCAATAATATATGATCATGATTACTGCCAACGGGGCTCCCAAAGCTTCGCCCAGCCCTTTCCAGCTATACTCCGACCATCACAAAATATCAGACTCTACAACATAGACGTTGAAGTGCAAGAAAATAGAAAGAGACTGTACGAAAATACAACTAAACTACTCAAGATCATGGCTTCGAAATCTAGAGCTAAAGTGAAAAAGGGCAAAAATATAGATGATCAAATTAAGATATGCAAATATGATCCACAGATGCTTCTATCTATGTCTAGGGAGATCGCCTCGAACTCACAAAATCCAGCCGATAAGCTTTTGGATATAGAAATGAGGAATTTATTTGGTAATATCCTCTTTACTCGTAATTCCGTTGAACCTCATGAGACGCTATTGCAAATGACATTTGAACTATGGCAAGGTTGGTACAATACAGGAAGGTTTATCCGTGACTGTCCACTGTTCTACCAATGCCATATATGCAACTTAGCGTGGTGGAGACTGCAGCCGTTCCGAGATCACATCCGCACCCATGATATTACTAACTTGAGGATATCTTTAAAAGAGAATATACACGAGTGCATGATTATAGCGAGCAATGATGCTGTGAAGAAACTAATGTTTATAGATATTGATGAGGATTGCTGGAAATGTGGAAAAGATGTTGAGTTTCACAAGAAATCGTCTGAAGTATACACTTGTATGAGATGCAAAAAGACTCAGTATACATGCTCAGCTTGGCGCAGTCATGAAACAAGATGTCTGTACAGTAATATATCCAATCACAATATAGCTAAGGAAAGGCAATGCACTGTTTGCGGTCAATTCATTGACTCGCTAGATCTTGTCGAGAAACATATGGTATTAGCCCACTCAGTGAGATCCGATGTGATCTCCCCAGTCACATACAAACACTGTAATAACTGTAACGAGAAATATTTCACCTACAACACACACAACTGCCCGAAAAGCTCGAAGAGTTCCGCATGTCAGTTTTGCTGTAGGAAATTCGCTTCGAAACCACTTACAACTATGCATACGCAATCTCCGCACAACAACCATGTAGTTTGTAGATTGTGTGGGAAATTTATACAAATGAAATGTCAAGAAATGGAGCATTTACTTATAAAACATTCACAGAACTATTCACTCGCGTACAGATGCACGCTCTGTACGGATGAATGCAAGATGTTTGTGGATGAATCATCTATTTCGCTGCATAGGATCAACTTGCATCAAAAGAAGTTGGACAAAAGGAGAACTTACTATGAATTGATGCTGGTACCGAAGCAAAGCTTGGAAACATACGTTCTAGAAGAGCGTGTACAAACCGTTGTGCTAGATGAAGCTGAAGCTAAAGCAATTCAAGTTCTGTCAGCTGATATTGATGTTATAGTAGACGAAGTAGACATTAAGAAGGAGCGAGTCTACGACGAAAATGGAGAGATCGATTATGAAGAAATGCTAAGAAACATGTTTGGTGATACGTCAAAAGACACGGGACTTACagataatgaaaataaagaaaCTGACGATAGTGAAAATGAcacaaaagaaaatattataatgtataGCGATGATGGTAAAATTAATGAAGAAAAAACGGAAAACTTTGATTTCGATATCGTTAAAGTCAAAACAGAGCCTACTGACATTGACATAATTGAGAATCCAATAGAAACTCAGATTGAAATCGTTGAAGTTAAATCTGAACCAGTAGATTATGAGGAAATTAATGAAGAAATTGAAGACCATAATCAAATTAATGAAGAAATGGAAGACCAGAATCAAGTTAATGAAGAAATTGTAGCTCACaatcaaattataaatgatATTGAAGATCACAATCAAACTAATAATGAAATTGATGACCACAATCAAATTGATAATGAAGTCGAAAAACAGAATCAAATTGATACTAAAGTCAAAGTCCAGAATCAAATTAAAAGTGAAGTTAAAAaccaaaatcaaattaaaaacgaAGTTGAAGACAAGATACAAATTAAAAACGAAGTTGACTTGTTAACAGTTAAAGTTGAACCGGACATAAATATGGACGACATAGCATCAgggaatattattataaagcgCGAAAATAACAGCGATGATGAAATAACAACGGACACTATACCCCTCGATCAGCTTCTTAAGTTCAACACCGACGGTGATATGGACTGGGTTTCAGAGGAGTTAAACCCTGATGAGATAACCTTTGACGTTTTAAGTCCGAGCGGGTTGTATAAGAGGAAGAAAATATATGCGTGCCATAAATGTGGTTACACAGCCCAATATAAACATTATAGTTTGCATGTTTCGTCTGGCTGTGCCGTCTCACCAAAAATGAACGAAAGTCATCCATGTTCAAAATGTGGTCTAACATTTGTTATGTTCAGAAATTATGTGTTGCATTTCGATAAGCATGGTTACAGTCCAATGTCGTGCCCTAAGTGTGGTGATACGTTCGATCAACAAGTTAAGCTTTTGTCTCATGTACAAAagcatattaaaaataattttgtcggCCTACATGTGTTGCATCGAGGTGGGGAAGAAACTTCTAAAGCCAATAAGGAAGTTAAaTGCCAAGAGTGTAGAAACGCTGTACCTCACTCGGACATGTTTCGACACTGGGAGGCGCATCTTACACTTAATACGCAACAGGAAACAACCTCGgATGTACCTGATTGTCGAGTGAAGGAAGAACAAGCGGAATATACTGTGGACTGTGAACGTGTCACTATGAATACTAAGATATTGGAGCCCAACACTCTTAAACAGGCTTTAGCATATAATATTGTTACAGACAGTTTACAATCGACGTCGTTAGCAGAGAAGACGTGTTCGGTATGTTACCGCGCGTTTGCGCGGCGCTGCGACGCGAAACGGCATATCGTGGAACATCTGCTAATGGACGCACACGTACAGAAGGtcaataataaGGGTTTCCGCTGTCAGATCTGTGGAGAGTGTTACCCACGACAAGAACAATACAAGTTTCATATGCGAGAACATGGTTCCATGCCTATATTTAAATGCGACATTTGCAATAAAACTTTCAGCGACTCGTCCAATTTCGCTAAGCATAAGAAAATCCACGGAGTACGGGTATTAGTCTGTGATACCTGCAAAAAGAAGTTCCACTCGAAATCAGCATTACAGAAGCATGTTTTGGAGCACAGTGTGATGAAACAGTTCCAATGTCCATATTGTGCTTCGTCGTTCAGTTTGAAACGTGAGCTCAAGCAACACAAACATAGATTTCATTCAAAGTACAAGTGCGTACTTTGCGATTTAACCTTCGAATCTTTACAATTCAAATGGAATCATGATTGGGAGgtacACAAGGAAAGGAAACATAAAGCAGACTGTCCTGTGTGTGGCAAGTCCTTCAGAAAACTTCAAGATGTGAAAAAACACGCACAAATTGAACACCGCGTACATATaccatataaaataaaaataaaaagtcaagcctaa
Protein Sequence
MSEGRKRSRKSKLEVRASDEYEVVNEQSDETSPPLQKVSRTRLQVEYPDVPIIYDHDYCQRGSQSFAQPFPAILRPSQNIRLYNIDVEVQENRKRLYENTTKLLKIMASKSRAKVKKGKNIDDQIKICKYDPQMLLSMSREIASNSQNPADKLLDIEMRNLFGNILFTRNSVEPHETLLQMTFELWQGWYNTGRFIRDCPLFYQCHICNLAWWRLQPFRDHIRTHDITNLRISLKENIHECMIIASNDAVKKLMFIDIDEDCWKCGKDVEFHKKSSEVYTCMRCKKTQYTCSAWRSHETRCLYSNISNHNIAKERQCTVCGQFIDSLDLVEKHMVLAHSVRSDVISPVTYKHCNNCNEKYFTYNTHNCPKSSKSSACQFCCRKFASKPLTTMHTQSPHNNHVVCRLCGKFIQMKCQEMEHLLIKHSQNYSLAYRCTLCTDECKMFVDESSISLHRINLHQKKLDKRRTYYELMLVPKQSLETYVLEERVQTVVLDEAEAKAIQVLSADIDVIVDEVDIKKERVYDENGEIDYEEMLRNMFGDTSKDTGLTDNENKETDDSENDTKENIIMYSDDGKINEEKTENFDFDIVKVKTEPTDIDIIENPIETQIEIVEVKSEPVDYEEINEEIEDHNQINEEMEDQNQVNEEIVAHNQIINDIEDHNQTNNEIDDHNQIDNEVEKQNQIDTKVKVQNQIKSEVKNQNQIKNEVEDKIQIKNEVDLLTVKVEPDINMDDIASGNIIIKRENNSDDEITTDTIPLDQLLKFNTDGDMDWVSEELNPDEITFDVLSPSGLYKRKKIYACHKCGYTAQYKHYSLHVSSGCAVSPKMNESHPCSKCGLTFVMFRNYVLHFDKHGYSPMSCPKCGDTFDQQVKLLSHVQKHIKNNFVGLHVLHRGGEETSKANKEVKCQECRNAVPHSDMFRHWEAHLTLNTQQETTSDVPDCRVKEEQAEYTVDCERVTMNTKILEPNTLKQALAYNIVTDSLQSTSLAEKTCSVCYRAFARRCDAKRHIVEHLLMDAHVQKVNNKGFRCQICGECYPRQEQYKFHMREHGSMPIFKCDICNKTFSDSSNFAKHKKIHGVRVLVCDTCKKKFHSKSALQKHVLEHSVMKQFQCPYCASSFSLKRELKQHKHRFHSKYKCVLCDLTFESLQFKWNHDWEVHKERKHKADCPVCGKSFRKLQDVKKHAQIEHRVHIPYKIKIKSQA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-