Basic Information

Gene Symbol
su(Hw)
Assembly
GCA_963565295.1
Location
OY751393.1:4475188-4482630[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.73 49 5.2 3.8 1 23 77 101 77 101 0.93
2 11 0.0069 0.46 11.6 0.1 2 23 109 131 108 131 0.94
3 11 4.3e-05 0.0029 18.5 2.7 2 20 137 155 136 157 0.94
4 11 1.8e-07 1.2e-05 26.0 0.8 1 23 167 190 167 190 0.98
5 11 0.094 6.3 8.0 5.1 1 23 196 219 196 219 0.92
6 11 0.00043 0.029 15.4 0.2 1 23 226 248 226 248 0.95
7 11 0.028 1.9 9.7 0.4 1 23 253 275 253 275 0.97
8 11 8.9e-06 0.0006 20.7 1.8 1 23 281 303 281 303 0.99
9 11 0.00024 0.016 16.2 0.9 1 23 306 328 306 328 0.95
10 11 2.9 1.9e+02 3.4 0.1 6 23 341 361 335 361 0.79
11 11 4.1e-05 0.0028 18.6 1.8 1 23 368 390 368 390 0.98

Sequence Information

Coding Sequence
atgcCCCCGAAGAAGAAAAGACAACCAGGAACAGCGAAGCAGAACTCGAAGAGTAGAAAACTAACTATAAAAGAAAAGCTAATATTTTTAGTGGGCAGTGAAGAAATTGATGACAGTGTTGTAAAGGAAGAGAGCTTGAGCAACGATGATAGCGGTAACTTTACTAACGGAGGTGATACTGATGATCAAAATGATCCCAACAGTCAACCTGTGGAGAAGATCAAGGTTTTTAATTGCAGGGTTTGCCAAAATAAGAACTTCAAGCATAAAGAGAAATATGAAACACATCTGCTCAATGAACACTCAACCACACCTGGTTCTGTTCCATGCAAAAAATGTCCTATAGTGTGTCCCGATAAAGAGTCATTAGTCCTTCACATTGTGAAAGCTCACAAACATCCAACAATCAAGTGCCAGCATTGCTCCAAAAAATTTACCCGACAGTCTCATGTGTTACGGCATATGGCTCAGAAAGGCTGTGGGAAAAAAATGGCAAAATTTCCATGTGAAatatgcCATGCCAGTTTTTCCCGAAAAGACAACTTGATAGTTCATCTTCGTACAACTCACCTAAGAAGTAATAGATTTTCATGTAAATATTGTAGTTTTTCTACAAAAAACTTCACAAAACTAACCAGGCATTGGCATGCAAATCATGCAGAGAATCCCAATCTGTTCCAATGTGATCTGTGTGGAAAAACAACCTCTTCCCGCGCAGCCATGGCCAAGCATAACGAGATACATGGAGAGAAAAAATATGCTTGTGATGTGTGTGGGTACAGCACGCACACAGTGGAGGTTATGCGTCGCCATGTATTGACGCATGTGGAGGACAAACCTTACAAATGCAGTCTTTGTCGGCGCTCGTACATTCAGCGCTCGCAACTACTGCGCCATCTAGAAACGCATGCGGGATTCATTTGTTTCTACTGCGAGAAACGCTTCCCCAATAAATCTGCCTTGCTGCTCCACAACAAAGAGCATAAGGGAGATTTGAAGCTTTTTTGTCCATACAACTGGTGTGACTATGCCAAAGAAGAGTTCAATACTGAAGAAAGTTATGATAATCACTTAAAAACTCATACCCAGGAAGAAAAATTATTCACGTGCGAGGTATGCAGCAAGCAGTTCATGAGCGAGCAGAACATGCGGCGGCACATGAGCACGCACACGCTGGACCGGCCGCGGCGCTGCATGTACTGCGTGTCGGCGCGCGCCTACATCCGCGGCATGCACCTCGTGCGCCACGTGCGCCACTTCCACAAGGACGTGTTCCAGGCGCATCTGGCGCATGTGCGCACCGTGCTCGTACGTACAACACTATCCAAGTTGGCCAAGAACCCAGGCAAGTCTCATGGATCAGAGCGACGCGTGAGCAAGTCTGAGCTGGAGTCGATCCTGAATGTGTTGGACGCGGAGTCTGACCGCATACTGGAGGGCTGCGCGGCCGGAACCGTCTTGTACGGCGGCATGCAGTTCGATCCTGACGAGACGGAGGAACAGTTCACTGACCTCACTGAAGATAGCCCACTGATGTCGGAAGAGATGCTTACAGAGCACCTCACGAAGCTGCTCGAGTACCTGATCGACGTGGAGACGTTGGAATGCCTCGGCTGGCCTGACGAACCTATCGATGACATCCTAGAAAAAGTTATTGAACAATGTGGCGCGAAGCCCGCTGATCGGCAAAAATGGACGCGCGTGCAGCGCCTGCGAGAAAACGCAAAGCATCTCTTCATACACGTCGTCGACGACAAGAACGTCGCCAAAATGCTCGACACGCACACCATTGACCAGATCATCAATCACATACTTGGTCAGTTCTCTGATGATGTTCTCTGA
Protein Sequence
MPPKKKRQPGTAKQNSKSRKLTIKEKLIFLVGSEEIDDSVVKEESLSNDDSGNFTNGGDTDDQNDPNSQPVEKIKVFNCRVCQNKNFKHKEKYETHLLNEHSTTPGSVPCKKCPIVCPDKESLVLHIVKAHKHPTIKCQHCSKKFTRQSHVLRHMAQKGCGKKMAKFPCEICHASFSRKDNLIVHLRTTHLRSNRFSCKYCSFSTKNFTKLTRHWHANHAENPNLFQCDLCGKTTSSRAAMAKHNEIHGEKKYACDVCGYSTHTVEVMRRHVLTHVEDKPYKCSLCRRSYIQRSQLLRHLETHAGFICFYCEKRFPNKSALLLHNKEHKGDLKLFCPYNWCDYAKEEFNTEESYDNHLKTHTQEEKLFTCEVCSKQFMSEQNMRRHMSTHTLDRPRRCMYCVSARAYIRGMHLVRHVRHFHKDVFQAHLAHVRTVLVRTTLSKLAKNPGKSHGSERRVSKSELESILNVLDAESDRILEGCAAGTVLYGGMQFDPDETEEQFTDLTEDSPLMSEEMLTEHLTKLLEYLIDVETLECLGWPDEPIDDILEKVIEQCGAKPADRQKWTRVQRLRENAKHLFIHVVDDKNVAKMLDTHTIDQIINHILGQFSDDVL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01529471;
90% Identity
-
80% Identity
-