Basic Information

Gene Symbol
-
Assembly
GCA_932294385.1
Location
CAKOAM010000059.1:2513727-2520622[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.0028 0.19 12.7 0.5 3 23 143 163 142 163 0.97
2 16 0.00017 0.011 16.6 0.7 1 23 167 190 167 190 0.92
3 16 9.3 6.4e+02 1.6 2.7 3 13 197 207 195 211 0.77
4 16 0.00027 0.019 15.9 0.8 1 23 215 238 215 238 0.92
5 16 9.3 6.4e+02 1.6 2.7 3 13 245 255 243 259 0.77
6 16 0.00012 0.0079 17.1 0.7 1 23 263 286 263 286 0.92
7 16 7.8 5.3e+02 1.9 0.7 3 9 293 299 291 299 0.88
8 16 0.023 1.6 9.8 0.3 5 23 326 344 325 344 0.95
9 16 0.00017 0.011 16.6 0.7 1 23 348 371 348 371 0.92
10 16 2.3e-05 0.0016 19.3 0.2 1 21 396 416 396 419 0.89
11 16 0.22 15 6.7 0.1 5 20 425 440 423 444 0.89
12 16 0.0041 0.28 12.2 1.3 1 23 450 473 450 473 0.97
13 16 1.7e-05 0.0012 19.7 1.4 1 23 479 502 479 502 0.98
14 16 0.00048 0.032 15.1 1.0 1 23 508 531 508 531 0.94
15 16 0.00038 0.026 15.5 1.2 1 23 538 560 538 560 0.97
16 16 1.6e-05 0.0011 19.7 3.6 1 23 563 585 563 585 0.99

Sequence Information

Coding Sequence
ATGACTCCCGATTTCGAAGATAAGTGTTTGGTTTGCTTAAAAACCGGCGGCAATTTGAATATCTTTACCACGTACAACATCAACAATGACAAAGAAGAATTATACGTTGAAGTCATTAAAAACTGCTTTAATGTGGAGATTACACGGGACTCTGGCCTCAACGCAATGTGCAATGAATGTAGCACTAAATTGAGAAAGGCATATACCTTCAAAAATGATGTTTTGATAGCTGTTAACAGACTAGTGGTTTTACAAGTGGAAAGGAAAGCTAAATCAAAGAAACCAGCCAAGAGTCAAAGTAAGAAGATTATAACAATAGAGGGTGAGCTGGTCAGTCCTACAGATCAAGAGGAGACTAATAAGAGGCCAAAGAAAGTGAAAGAAGCCAAGAAGCCCCCCTTCACTCTCCAGGCTGGCCAAACGTTGTGCGCACTCTGCGGCGCTCAGTTCGAAACGCACAAGGCGCTGAACACACACATGAACGCTCACTTCCCCGACCACGTCTGCAATGAGTGCGGGATGGCGTTCGCGAGTCAGAGCCGGCTGAGGATGCACAGATATCAAGCACACGTCGACGGGCCGATAAACTGCAAGTACTGTGACAAGGCGCTGAATACACACATGAACGCGCACTTCCCCGACCACGTCTGCAATGAGTGCGGGATGGCGTTCGCGAGTCGGAGCCGGCTGAGGATGCACAGATACCAAGCACACGTGGACGGGCCGATAAACTGCAAGTACTGCGACAAGGCGCTGAACACACACATGAACGCTCACTTCCCCGACCACGTCTGCAATGACTGCGGGATGGCGTTCGCGAGTCAGAGCCGGCTGAGGATGCACAGATACCAAGCACACGTGGACGGGCCGATAAACTGCAAGTACTGCGACAAGTCAGAGCCGGCTGAGGATGCACAGATACCAAACACACGTCGATGGGCCGATAAACTGCAAGTACTGCGACAAGGTATGTCACTCTGCGGCGCTCAGTTCGAAACGCACAAGGCGCTGAATACACACATGAACGCGCACTTCCCCGACCACGTCTGCAATGAGTGCGGGATGGCGTTCGCGAGTCAGAGCCGGCTGAGGATGCACAGATACCAAGCACACGTCGACGGGCCGATAAACTGCAAGTACTGCGACAAGGCGCTGAATACACACATGAACGTGCACTTCCCCGACCACGTCTGCAATGAGTGCGGGATGGTGTTCCCGAGTCAGAGCCAGCTGAGGATACACGGATACCAGGCACACGTCGATGGGCCGAAGAACTGCGATAAGAGTTTCACCAACGTGAACACCCGTAACGCGCACATGTGGCGCGTCCACACGAAGACCGACCCCTTCAAGTGTGCCCAGTGCGGCGCGCGCTTCAAGACGTATCTCAAGCGGCTGAGGCATATGCAGAGCGCGCACGGAGAAACAGTTGAATACCAGTGCCAGTACTGTGATAAGAAGTTCGCTTACGCTGCATACAGAACGAAGCACGTCCGCACGATCCACCTCGAATCCCGCCCCCACAAGTGTCCCAGCTGCCCCTACAGCTTCGCGCGCCGCCGCGAGCTGGACGCGCACCGCGCCAACAAACATGGCGACGGCGGGATGAAGTACCAATGCGATGCGTGCGACAAGAAGTTCTTCTTCAAGAGCGCGCTGAAGATGCACGTCAGTTTGCATAACAGATTCACATGCAACCAGTGCGACGCGAAATTCACCCACGCGCGAGAACTGGAAGCGCACCACCGCACACACGAGTTCGCGGACATGCCGGAGCTGCCCATCCTCGACCCCGCGCAGTTCGACGCGTTTGCGGACTACGCGCTGGACTGGGTGCTGGCTCCCTAG
Protein Sequence
MTPDFEDKCLVCLKTGGNLNIFTTYNINNDKEELYVEVIKNCFNVEITRDSGLNAMCNECSTKLRKAYTFKNDVLIAVNRLVVLQVERKAKSKKPAKSQSKKIITIEGELVSPTDQEETNKRPKKVKEAKKPPFTLQAGQTLCALCGAQFETHKALNTHMNAHFPDHVCNECGMAFASQSRLRMHRYQAHVDGPINCKYCDKALNTHMNAHFPDHVCNECGMAFASRSRLRMHRYQAHVDGPINCKYCDKALNTHMNAHFPDHVCNDCGMAFASQSRLRMHRYQAHVDGPINCKYCDKSEPAEDAQIPNTRRWADKLQVLRQGMSLCGAQFETHKALNTHMNAHFPDHVCNECGMAFASQSRLRMHRYQAHVDGPINCKYCDKALNTHMNVHFPDHVCNECGMVFPSQSQLRIHGYQAHVDGPKNCDKSFTNVNTRNAHMWRVHTKTDPFKCAQCGARFKTYLKRLRHMQSAHGETVEYQCQYCDKKFAYAAYRTKHVRTIHLESRPHKCPSCPYSFARRRELDAHRANKHGDGGMKYQCDACDKKFFFKSALKMHVSLHNRFTCNQCDAKFTHARELEAHHRTHEFADMPELPILDPAQFDAFADYALDWVLAP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00659970;
90% Identity
iTF_00659970;
80% Identity
iTF_00659970;