Enis003333.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Epinotia nisella
Gene Symbol
NFYA
Assembly
GCA_932294385.1
Location
CAKOAM010000012.1:5171268-5184031[-]

Transcription Factor Domain

TF Family
NF-YA
Domain
CBFB_NFYA domain
PFAM
PF02045
TF Group
Other Alpha-Helix Group
Description
Diverse DNA binding proteins are known to bind the CCAAT box, a common cis- acting element found in the promoter and enhancer regions of a large number of genes in eukaryotes. Amongst these proteins is one known as the CCAAT-binding factor (CBF) or nuclear transcription factor Y (NF-Y) [1]. CBF is a heteromeric transcription factor that consists of two different components both needed for DNA-binding. The HAP protein complex of yeast binds to the upstream activation site of cytochrome C iso-1 gene (CYC1) as well as other genes involved in mitochondrial electron transport and activates their expression. It also recognises the sequence CCAAT and is structurally and evolutionary related to CBF. The first subunit of CBF is known as CBF-A or NF-YB in vertebrates, and HAP3 in budding yeast. The second subunit is known as CBF-B or NF-YA in vertebrates and HAP2 in budding yeast. It is a protein of 265 to 350 amino-acid residues which contains a highly conserved region of about 60 residues. This region, called the 'essential core' [2], seems to consist of two subdomains: an N-terminal subunit-association domain and a C-terminal DNA recognition domain.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 22 6.1e-14 1.5e-09 38.7 0.3 3 33 178 208 176 213 0.93
2 22 6.1e-14 1.5e-09 38.7 0.3 3 33 219 249 217 254 0.93
3 22 6.1e-14 1.5e-09 38.7 0.3 3 33 260 290 258 295 0.93
4 22 6.1e-14 1.5e-09 38.7 0.3 3 33 301 331 299 336 0.93
5 22 6.1e-14 1.5e-09 38.7 0.3 3 33 342 372 340 377 0.93
6 22 6.1e-14 1.5e-09 38.7 0.3 3 33 383 413 381 418 0.93
7 22 6.1e-14 1.5e-09 38.7 0.3 3 33 424 454 422 459 0.93
8 22 6.1e-14 1.5e-09 38.7 0.3 3 33 465 495 463 500 0.93
9 22 6.1e-14 1.5e-09 38.7 0.3 3 33 506 536 504 541 0.93
10 22 1.9e-13 4.9e-09 37.1 2.0 3 33 547 577 545 582 0.92
11 22 1.8e-13 4.5e-09 37.2 1.9 3 33 582 612 579 617 0.93
12 22 6.1e-14 1.5e-09 38.7 0.3 3 33 623 653 621 658 0.93
13 22 6.1e-14 1.5e-09 38.7 0.3 3 33 664 694 662 699 0.93
14 22 6.1e-14 1.5e-09 38.7 0.3 3 33 705 735 703 740 0.93
15 22 6.1e-14 1.5e-09 38.7 0.3 3 33 746 776 744 781 0.93
16 22 6.1e-14 1.5e-09 38.7 0.3 3 33 787 817 785 822 0.93
17 22 6.1e-14 1.5e-09 38.7 0.3 3 33 828 858 826 863 0.93
18 22 6.1e-14 1.5e-09 38.7 0.3 3 33 869 899 867 904 0.93
19 22 6.1e-14 1.5e-09 38.7 0.3 3 33 910 940 908 945 0.93
20 22 6.1e-14 1.5e-09 38.7 0.3 3 33 951 981 949 986 0.93
21 22 6.1e-14 1.5e-09 38.7 0.3 3 33 992 1022 990 1027 0.93
22 22 2.6e-29 6.6e-25 87.9 6.6 3 56 1033 1086 1031 1086 0.99

Sequence Information

Coding Sequence
ATGGAGCACGCTCAGATCCAGAGCTCGGACGGCACGCAGGTGATGACCATCAATGGACAGCAGCTGCAAGTGCTGCAGATGAACAATGCTGGCCCGCACATGATACAGGGGCCCAACGGGCAGCAGATTGTGGTGCATGCCATACCAACTAACGCACCTACTATTCAGATGACGACACCTAACGGACAACAACTCCAGCAATTACAAGTCTTACCGCTATCCAGTCTTCAAGGCACAAGCAACAACATGCAGCCGATGCAGCTAGTCCAAACGGCAGACGGACAGACATTCATCTATCAACCGACCGCCAACGCTCCACAGCCCACCATAGACCAGCATCAGCTCATTCACCAACCAGCCGTAATCAATTTGAACGGTAATCTGGTGCAAGTGTCGGGCGCCGTCAATACGGTGCAGCAGCAGCAAGTCGTCAACCAGCCCAATATTGTGATGATGGTGAACAACGGCAGCAACAGCGCCGCGAGCGCGTCCTCCGCGCCGGAGGCGGCGGGCTCGGACGAGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGGCGGCGGGCTCGGACGAGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGGCGGCGGGCTCGGACGAGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGGCGGCGGGCTCGGACGAGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGGCGGCGGGCTCGGACGAGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGGCGGCGGGCTCGGACGAGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGGCGGCGGGCTCGGACGAGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGGCGGCGGGCTCGGACGAGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGGCGGCGGGCTCGGACGAGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGGCGGCGGGCTCGGACGAGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGGCGGCGGGCTCGGACGAGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGGCGGCGGGCTCGGACGAGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGGCGGCGGGCTCGGACGAGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGGCGGCGGGCTCGGACGAGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGGCGGCGGGCTCGGACGAGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGGCGGCGGGCTCGGACGAGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGGCGGCGGGCTCGGACGAGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGGCGGCGGGCTCGGACGAGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGGCGGCGGGCTCGGACGAGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGGCGGCGGGCTCGGACGAGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGGCGGCGGGCTCGGACGAGGAGCCGCTGCTGTACGTGAACGCGCGCCAGTACAAGCGCATCCTCAAGCGCCGCGCCGCGCGCGCCAAGCTGCACGAGCAGGGCAAGATCCCCAAGGAGCGACCGAAATACCTGCACGAATCGAGACACAGGCACGCAATGAACCGAATACGCGGTGAGGGCGGCAGGTTCCACTCCGGTAGTAGGAAGAACATGGAACCGGTGGAACAGGGATCGGAGGAAGAACACAAGCCCTTGGAGGACATCAAACCGGACACAGTATCGATCACAATCATTCAGGACGAGGAATCCCAAGAGCGCCAACGGAGTCAATGGCGGCGCCTCGCGCCCCACCTGCCCGTGCCCTCTGCGTAG
Protein Sequence
MEHAQIQSSDGTQVMTINGQQLQVLQMNNAGPHMIQGPNGQQIVVHAIPTNAPTIQMTTPNGQQLQQLQVLPLSSLQGTSNNMQPMQLVQTADGQTFIYQPTANAPQPTIDQHQLIHQPAVINLNGNLVQVSGAVNTVQQQQVVNQPNIVMMVNNGSNSAASASSAPEAAGSDEEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPAAGSDEEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPAAGSDEEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPAAGSDEEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPAAGSDEEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPAAGSDEEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPAAGSDEEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPAAGSDEEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPAAGSDEEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPAAGSDEEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPAAGSDEEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPAAGSDEEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPAAGSDEEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPAAGSDEEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPAAGSDEEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPAAGSDEEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPAAGSDEEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPAAGSDEEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPAAGSDEEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPAAGSDEEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPAAGSDEEPLLYVNARQYKRILKRRAARAKLHEQGKIPKERPKYLHESRHRHAMNRIRGEGGRFHSGSRKNMEPVEQGSEEEHKPLEDIKPDTVSITIIQDEESQERQRSQWRRLAPHLPVPSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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