Basic Information

Gene Symbol
-
Assembly
GCA_945869435.1
Location
CAMBUM010000448.1:61924-73710[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 6.4 6.3e+02 2.6 1.0 1 8 185 192 185 193 0.90
2 14 0.001 0.1 14.6 6.9 2 23 196 217 195 217 0.97
3 14 0.0041 0.4 12.7 7.5 1 23 223 245 223 245 0.97
4 14 0.00056 0.055 15.4 9.0 1 23 251 273 251 273 0.99
5 14 0.00093 0.09 14.7 5.5 1 23 279 301 279 301 0.96
6 14 0.0017 0.16 13.9 11.2 1 23 307 329 307 329 0.98
7 14 0.005 0.49 12.4 5.7 1 23 335 357 335 357 0.99
8 14 2.9 2.8e+02 3.7 0.4 5 20 364 379 362 381 0.91
9 14 0.024 2.3 10.3 7.2 1 23 388 410 388 410 0.98
10 14 0.0062 0.6 12.1 7.3 1 23 416 438 416 438 0.97
11 14 2.9 2.8e+02 3.7 1.5 5 23 445 463 443 463 0.94
12 14 0.00013 0.012 17.4 6.2 1 23 469 491 469 491 0.98
13 14 0.018 1.8 10.7 6.8 1 23 497 519 497 519 0.97
14 14 0.043 4.2 9.5 2.1 5 23 526 544 524 544 0.96

Sequence Information

Coding Sequence
ATGCAACCGGAAGTGGAACCAGAGATCGCGATCCGTTTCAGTCAAATCCTGATTATGGCAAAGTATAATGTTGCCAGCTTACCATGGGTTCTGTGGTGTTCTGGCTTCTTACATTTCGCAGCACTACGTGCGGCGACATCAGCTATAGATTTACGTACCATGTCACTAGAAACATTGTGTGTGAAGACTGAGGTGGAGGTGGTGCGAGTGAAAGAGGAGGCTGAGGTGTTTGAACATGAGGAGACCGGGGCACATGAAAAGGAGGATTTGGAGTGTGAGGACAACCCCGACTTGCGTGCCCTGTACGCAGGCCACCAGGTCAAGGACGAGCTTGTGCTGGGCCCCGTGGAGCTGCACGGGCATCGTGTGCTCTCCAGTCTTTCAACGGCACCGAGCGGCGCAGAGGAGGCTCGCGGGCGGGCTTGCTCGGTCAGGCTGGAGCGCCTGCTCGTGGACGCGGAGCGGCGCTCGTGCCGGGTCGGGCTCCGCACGTACCCGCTGCGGCGCACGCGCGACCCACGCGACGACGCCGACACGTCGAGCAGCGCGACCTATCAGTGTGACGAGTGTGGTGAGAAACCGTTGAAATGTAGCCACTGTGACTACAAGTGCAGTCGGAAGAGAGATTTAGAAATTCACAAGAGGAGACACACTGGAGAAAAACCATTTCATTGTAGCCACTGTGACTACAAATGCAGTCAGAAGGCAAGTTTAAAAGTTCACGAGAGACTTCACACTGGAGAAAAACCATTTAAATGTAGCCACTGTGACTACAAATGCAGTCAGAAGGCACATTTAAAAATTCACGAGAGACGACACACTGGCGAAAAATCATTTAAATGTAGCCACTGTGACTACAAATGCAGTCAAAAGGGAAGTTTAAAAAATCACGAGATACTACACACAGGAGAAAAACCATTTAAATGTAGCCACTGTGACTACAAGTGTTGTCGGAAGGGATCTTTAAAAAGGCACCAGAGCCGTCACACTGGAGAAAAACCATTTAAATGTAGCCACTGTGACTACAAATGCAGACTGAAGGCAGGTTTAAAAATTCACGAGAGACGACACACTAGAGAAAAACCATTTAAGTGTGACTACAAATCCAGTCAGAAGGAATGTTTAAAAATTCACAAGGGGAGAAACACAGGAGAAAAACCATTTAAATGTAGCCACTGTGACTACAAAAGCAGTTGGAAGGAACATTTAAAAAGGCACCAGAGCCGACACACTGGAGAAAAACCATTTATATGTAGCCACTGTGACTTCAAATGCAGTCAGAAGACAAGTTTAAAAAGGCACGAGAGCCGACACACTGGAGAAAAACCATTCTATTGTGACTACAATTGCAGTTGGAAGGACTGTTTAGAAAGTCACAAGAGGAGACACAGGGGAAAAACACCATTTAAATGTAGCCAGTGTGACTACAAAAGCAGTCGGAAGGAACATTTAAAAAGGCACCAGAGCCGACACACTGGAGAAAAACCATTCATATGTAGCCACTGTGACTTCAAAAGCAGTCACAAGACAAGTTTAAAAAGGCACGAGAGCCGACACACTGGAGAAAAACCATTTAATTGTGACTACAAGTGCAGTCGGAAGGAATGTTTAGAAATTCACAAGAGGAGACACACTGGAGAAAAACCATATAAATGTAGCCAGAGTGTAGAAGTAGAAGAAAGTGACGATGATGAAAACCTTACACCAGGGAGAAGCATTCACACTCCCCCAGTCTCTCGGTGGGCTGATATCATAGGGGTGTCCGGCCCACAAGATTATACTTTTAACAAGAGCCGAGAACACACCGCCGACTTATAA
Protein Sequence
MQPEVEPEIAIRFSQILIMAKYNVASLPWVLWCSGFLHFAALRAATSAIDLRTMSLETLCVKTEVEVVRVKEEAEVFEHEETGAHEKEDLECEDNPDLRALYAGHQVKDELVLGPVELHGHRVLSSLSTAPSGAEEARGRACSVRLERLLVDAERRSCRVGLRTYPLRRTRDPRDDADTSSSATYQCDECGEKPLKCSHCDYKCSRKRDLEIHKRRHTGEKPFHCSHCDYKCSQKASLKVHERLHTGEKPFKCSHCDYKCSQKAHLKIHERRHTGEKSFKCSHCDYKCSQKGSLKNHEILHTGEKPFKCSHCDYKCCRKGSLKRHQSRHTGEKPFKCSHCDYKCRLKAGLKIHERRHTREKPFKCDYKSSQKECLKIHKGRNTGEKPFKCSHCDYKSSWKEHLKRHQSRHTGEKPFICSHCDFKCSQKTSLKRHESRHTGEKPFYCDYNCSWKDCLESHKRRHRGKTPFKCSQCDYKSSRKEHLKRHQSRHTGEKPFICSHCDFKSSHKTSLKRHESRHTGEKPFNCDYKCSRKECLEIHKRRHTGEKPYKCSQSVEVEESDDDENLTPGRSIHTPPVSRWADIIGVSGPQDYTFNKSREHTADL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-