Basic Information

Insect: Epinotia demarniana
Gene Symbol: zfh1
Assembly: GCA_945869435.1
Location: CAMBUM010000836.1:30656-40501[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.03 2.9 10.0 0.3 1 23 73 95 73 95 0.94

2 8 9.9e-06 0.00096 20.9 1.9 1 23 106 128 106 128 0.97

3 8 2.7e-06 0.00026 22.7 6.2 1 23 137 159 137 159 0.99

4 8 0.00019 0.019 16.9 1.0 1 21 165 185 165 186 0.95

5 8 0.015 1.5 10.9 0.8 1 20 444 463 444 465 0.93

6 8 1.4e-05 0.0014 20.4 1.1 1 23 761 783 761 783 0.94

7 8 9e-05 0.0087 17.9 7.2 1 23 789 811 789 811 0.98

8 8 0.1 9.8 8.3 7.1 1 21 817 837 817 838 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.03	2.9	10.0	0.3	1	23	73	95	73	95	0.94
2	8	9.9e-06	0.00096	20.9	1.9	1	23	106	128	106	128	0.97
3	8	2.7e-06	0.00026	22.7	6.2	1	23	137	159	137	159	0.99
4	8	0.00019	0.019	16.9	1.0	1	21	165	185	165	186	0.95
5	8	0.015	1.5	10.9	0.8	1	20	444	463	444	465	0.93
6	8	1.4e-05	0.0014	20.4	1.1	1	23	761	783	761	783	0.94
7	8	9e-05	0.0087	17.9	7.2	1	23	789	811	789	811	0.98
8	8	0.1	9.8	8.3	7.1	1	21	817	837	817	838	0.96

Sequence Information

Coding Sequence: ATGAAAGTGCAGAGCCCTCTTATGGGAGTTGGCGGTTTGTACGAATGCTTGGCGGCCGGTTGGCTTGCGGACATGAGGAGTAAGCAGGTCCCCACCTCCACGACCTCCGCCAGGCGGCTCGCTGCCTTAAtCCGCCCCTTTACGGGCGGCGGGGAGGGCAAGCCACCGGACGAAGAGGAGGACCGAGGCGGGTCCCCGCTGGGCCCGGGCGGGCCGTTCAGCTGCAGCCAGTGCCGCGGAGCCTACCCCACCCGCGAGCAGCTCGAGCGACACGAGACCCTGCACTCGCCCAACACTCAGGTGGATACCATCAAATATGCATGCAAGATCTGCCACAAAAGCTTCGCAAACGTATACCGGCTGCAGCGGCACATGATCAGCCACGACGAGAGCGCGAACCTTCGCAAGTTCAAATGCAACGACTGCGACAAAGCCTTTAAATTTAAGCATCACCTTAAGGAGCACCTCCGCATTCACTCCGGGGAGAAGCCCTTTGAGTGCGCCAACTGCGGGAAGAAGTTCTCGCACTCTGGCTCCTACTCTTCGCACATGACGTCTAAGAAGTGTCTGGTTATGAATCTCAAAATGGGCCGCATCAAGCCCAACAATCCCGCGCTCAACCCCGACCGCAGTCCGTCACGCAAGCGCGCTAATGCCATGGCTAGCCAGCTAAATAACAACATCGCGCCCAATGGAAGCTCATTCCTGCCCATCCTTCCTAAATATAACGAGGCAGCGTTCTTCGCCAACATGTCGCAAGACAACGGTTTTCACCGCTCACCGCTGGGCAGAATGCCATTTTACATGCCTCCCGGCATGCCGATGAGCCCGGCGAACGGTATTGCTCCCTATAGCTTTCCAGCGCAACTCACCCAGTTATTTGAGCAACTTGCTTCGACACAGTATCACCAAAGAAAAATGGAACATCCCATGAGCCCGAAGCGGAGCCCTCATCATGCAGACCCCGAGGACATGATCGAAGAAGTGACCGAAGAAGATGACAAGCGGTCGGAGGGAAGCGCTGAACTAGTGATGGACATCGAGGATGAAGAAGCAGTTGCTATTAAAAAAGAACGAGAGGAGCGAGAATGTGATCTGCGGTCACCCACTCGCAACTTGGAATCCGTCCCTTTAAATAATAATGGCCCCGAAGCCGACAACAACCAATCAAATTTCAACACGATATTAGAATCAGTTAGCGCCTCAGTAACCAAACATTTCTTTAGAGCTAATGTGGACAAGATGTCTCCTATGTCTGGTAGCATTTGTCCAAGCATAGAGTCGCCGCCGACCCCACACGTCGTCATCAAAGACGAGCCTGATGATGTACATAAATGCCTGAAATGCAGCAACATTTTCAGAACTAAAAGCGATTTATTAGACCACGAAAAAGCATTTTGTGGGAATATAATAACATTCAGAAAACACGAAGGCTTGGCAGCACAAGTTGAGGAAACGGTAGCTCTCAATAGACTAGAAGCCGAAATGCGGGCATCCATCCAAAGCGGTGTCAGCGCCAGTGAAGATGAAGACTTCAGTAGGGAAGACCGCGACGAGAAAAGCTCGACGCACGATGGGGACAGAAAAATCAGAGTTCGGACAAACTTGACTGACGAGCAGCAAGCTATTTTAAAACAACACTACGCTGTTAACCCTCAGCCAAAACGCGAGGAATTCAAAAAGATTGCGCAGCAGATCGGTCTACATAATAGAGTAGTGCAAGTCTGGTTCCAAAATAACAGAGCCAGAGTACGAAGAATGACTCAAACCGTAGCGGTATACGACCAGCCCCTGGACCTATCGACCAAAAAGTCGAGCGCGTCCATTACGTCGAGCCCGTCCCCATCGCCGCCTTGCAGCATTTCCGTCACACATTCCGACTCCGAGGAAGCGGTCAACCTGAGCCAAAAGTCCTCCCGCAGCACGACGCCTCAACGTAACAACTATTTGAACGCGTACCCACATTCCAATTGTTCTTCGTCCTCCTTCACTGACTTCCGTTTATCGCCTTCCCCGGGGGAGATGGGTGCTCAGAAACGGCCTCTGGCACATAAGTTGAATCCGACAATACCGATGGACAAGCTGTTACAATACAACGACATGGCAAACACGCGGTCACCTCTCCTTAACATGCATATGGATCGGGCGCCTGGGTTGAGTCCATCGTACGAGCGGCCGCTGTGGGGGGAAGAGATGCTCGCGCCTGCAGACTACGACGACGAAGGGCCGGTACTTAAGAAGAATAAGCTGAAGATGGAGTTTAAGGAGGGCGAGGGCCAGTTCGTATGCGACCAATGCGACAAGACCTTCGTCAAGCAGAGCTCACTCGCGCGCCACAAGTACGAGCACTCAGGTCAGCGGCCCTACAAGTGCGTGGAGTGCCCGAAGGCTTTCAAGCACAAGCACCACCTCACGGAGCACAAGCGGCTGCACACCGGCGAGAAGCCGTTCCAATGCTGCAAGTGCCTCAAGAAGTTCTCCCACTCGGGCTCCTACAGCCAGCACATGAACCACCGCTTCGCCATCTGCAAACCCTACCGGGACTAG
Protein Sequence: MKVQSPLMGVGGLYECLAAGWLADMRSKQVPTSTTSARRLAALIRPFTGGGEGKPPDEEEDRGGSPLGPGGPFSCSQCRGAYPTREQLERHETLHSPNTQVDTIKYACKICHKSFANVYRLQRHMISHDESANLRKFKCNDCDKAFKFKHHLKEHLRIHSGEKPFECANCGKKFSHSGSYSSHMTSKKCLVMNLKMGRIKPNNPALNPDRSPSRKRANAMASQLNNNIAPNGSSFLPILPKYNEAAFFANMSQDNGFHRSPLGRMPFYMPPGMPMSPANGIAPYSFPAQLTQLFEQLASTQYHQRKMEHPMSPKRSPHHADPEDMIEEVTEEDDKRSEGSAELVMDIEDEEAVAIKKEREERECDLRSPTRNLESVPLNNNGPEADNNQSNFNTILESVSASVTKHFFRANVDKMSPMSGSICPSIESPPTPHVVIKDEPDDVHKCLKCSNIFRTKSDLLDHEKAFCGNIITFRKHEGLAAQVEETVALNRLEAEMRASIQSGVSASEDEDFSREDRDEKSSTHDGDRKIRVRTNLTDEQQAILKQHYAVNPQPKREEFKKIAQQIGLHNRVVQVWFQNNRARVRRMTQTVAVYDQPLDLSTKKSSASITSSPSPSPPCSISVTHSDSEEAVNLSQKSSRSTTPQRNNYLNAYPHSNCSSSSFTDFRLSPSPGEMGAQKRPLAHKLNPTIPMDKLLQYNDMANTRSPLLNMHMDRAPGLSPSYERPLWGEEMLAPADYDDEGPVLKKNKLKMEFKEGEGQFVCDQCDKTFVKQSSLARHKYEHSGQRPYKCVECPKAFKHKHHLTEHKRLHTGEKPFQCCKCLKKFSHSGSYSQHMNHRFAICKPYRD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00462280;
90% Identity: iTF_00149268;
80% Identity: iTF_00658251;