Basic Information

Insect: Epinotia demarniana
Gene Symbol: mnm-2
Assembly: GCA_945869435.1
Location: CAMBUM010000874.1:241356-257099[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.002 0.2 13.7 0.2 1 23 101 123 101 123 0.97

2 19 0.00036 0.035 16.0 2.9 1 23 150 171 150 171 0.98

3 19 0.00026 0.026 16.4 1.0 1 23 177 199 177 199 0.96

4 19 7.8e-06 0.00076 21.2 1.9 1 23 205 227 205 227 0.98

5 19 3.8e-07 3.7e-05 25.4 1.1 1 23 233 255 233 255 0.99

6 19 6.6e-06 0.00065 21.5 3.6 1 23 261 283 261 283 0.99

7 19 0.00048 0.046 15.6 6.6 1 23 366 388 366 388 0.98

8 19 0.24 23 7.1 1.7 1 23 518 540 518 540 0.96

9 19 0.0027 0.26 13.3 0.3 1 23 707 729 707 729 0.98

10 19 0.00037 0.036 16.0 1.5 1 23 757 778 757 778 0.98

11 19 9.6e-05 0.0094 17.8 0.1 1 23 784 806 784 806 0.98

12 19 5.3e-07 5.2e-05 24.9 0.7 1 23 812 834 812 834 0.98

13 19 4e-08 3.8e-06 28.5 1.0 1 23 840 862 840 862 0.99

14 19 4.3e-07 4.2e-05 25.2 2.9 1 23 868 890 868 890 0.98

15 19 4.7e-07 4.6e-05 25.1 1.4 1 23 1066 1088 1066 1088 0.99

16 19 3e-05 0.0029 19.4 0.5 1 23 1094 1116 1094 1116 0.98

17 19 0.0017 0.16 13.9 1.1 1 23 1122 1144 1122 1144 0.98

18 19 0.001 0.1 14.6 1.8 1 23 1150 1173 1150 1173 0.95

19 19 3.2e-05 0.0031 19.3 0.8 1 23 1179 1201 1179 1201 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.002	0.2	13.7	0.2	1	23	101	123	101	123	0.97
2	19	0.00036	0.035	16.0	2.9	1	23	150	171	150	171	0.98
3	19	0.00026	0.026	16.4	1.0	1	23	177	199	177	199	0.96
4	19	7.8e-06	0.00076	21.2	1.9	1	23	205	227	205	227	0.98
5	19	3.8e-07	3.7e-05	25.4	1.1	1	23	233	255	233	255	0.99
6	19	6.6e-06	0.00065	21.5	3.6	1	23	261	283	261	283	0.99
7	19	0.00048	0.046	15.6	6.6	1	23	366	388	366	388	0.98
8	19	0.24	23	7.1	1.7	1	23	518	540	518	540	0.96
9	19	0.0027	0.26	13.3	0.3	1	23	707	729	707	729	0.98
10	19	0.00037	0.036	16.0	1.5	1	23	757	778	757	778	0.98
11	19	9.6e-05	0.0094	17.8	0.1	1	23	784	806	784	806	0.98
12	19	5.3e-07	5.2e-05	24.9	0.7	1	23	812	834	812	834	0.98
13	19	4e-08	3.8e-06	28.5	1.0	1	23	840	862	840	862	0.99
14	19	4.3e-07	4.2e-05	25.2	2.9	1	23	868	890	868	890	0.98
15	19	4.7e-07	4.6e-05	25.1	1.4	1	23	1066	1088	1066	1088	0.99
16	19	3e-05	0.0029	19.4	0.5	1	23	1094	1116	1094	1116	0.98
17	19	0.0017	0.16	13.9	1.1	1	23	1122	1144	1122	1144	0.98
18	19	0.001	0.1	14.6	1.8	1	23	1150	1173	1150	1173	0.95
19	19	3.2e-05	0.0031	19.3	0.8	1	23	1179	1201	1179	1201	0.98

Sequence Information

Coding Sequence: atgACGTTTATGCAATTGGGTGCTTTCAAAACTCATGAACTCATTCACACGGAAGAAAAGGGTGCGCGGGGCGAGTTGTACGCCCAGGGGACTAAGGACGAGCTCATGCTTGGGCCGGGAGATAGGCAGCGGCCCTACAGAGTCAATGCCTTTGGTGGTAAGATTGAAAAACCTGAGTCTTTAATTCGTGACTACGAGCCTGCGCTCACAACCTACCGTGAGCCCGCCCCGACCACGAGCGCTGAACACGAAACCGCACAAAATAATACATTCTCCTACACCATGCAACCGACACATATCTACATGTGCGGCACTTGCGGGGAAATATTCCAGCAAAAACAATATCTAATCGACCATGTTAAAGCACACCTTCGGGAAAGCTCAGTCACATTACTGAACAAGTCTTCCATCCTCGAACCCAGTGCCACAGACATGAGTGTAACGAAATATTCCtgcaaaatatgtaaaaaaaggtTCCGAAAGGATTACTTAAAGATCCACGAGCGGTTGCACACAGGTCAGAAAGCTCATGCGTGCGAAGTATGTAAGAAGCAGTTTGCTACTTTGGGCAGTTTGAGGGAACATAAACGTATCCACACTGAAATTAGGCCTTACTCGTGTGATGTATGTACAAAAAGTTTCGTGAGATTGGACCATTTAAAAATACACGAACGCAGTCACACTGgagaaaaaccatacaaatgtgaaaCGTGTAAAAAGGCATTCTCGCAATTACCTAATTTACAATCACATATACGAACACACACTGGAGAAAAACCATATGTATGCAAGACGTGTGACAAGCAGTTTACGCAATGGAGCGCTCTCCATAACCATAAAAAGACACACTCAGTTGAAAAGCCACACTCGTGTGAAATAACAACAAACCCGTGCGCAGCGACCGAGAAGTATAAGGAGAGGACTCGCGTGAGGGAAGAACCTAAGTGTGAGAGCAGGGCAGACTCTTGCAGTGTGAGTGAGACGGGTTCTAGCGTCAATCTCGTGATGAAGGTCGAGCTGGAGCTGGGACCGGAGGGCGTACAGCAACGCGATATACCCATCGCGCCTCGCGCCGCACCGCCGCGCTGCGAGCTTTTCTCGTGCGAAACGTGTAATAAGACTTTCAGAAAACAGAGCAGTTTTGAAAATCATAGACATAAACACGAGGCAGTCAGCGTGAAAGAGAAATCCGAGAGTGAGAGCAGTACAGACCCGCCGGAAGCGAGCGAGACGCATAAGGAGACTCGTGTGAAGGAAGATTCTAAGTGTGAGAGCAGTGCAGACTCATGTGGAGTGAGCGAGATGGGTGCAAACGGCGACCACGTGATTGTGGTCGAGCCGGAGCTGGGACCGGGTCACACGCAGCGCCCCAACATATTCAATGCCCTTGGTGAAAAATCGCGGTTCTTGGTTCGTAACTACAGGCCTGCGCTCGACTACTGCGCCGATACATCTCACTGCGAGCCGGCCGGGACCACGGACGCTGAACACGATACCGTACAACATAATACGATCACCGAAACTCTGCAACATACGGCGAAGACACAAACTTACATGTGCGGCACTTGCGGAGAAATGTTCTTACAAAAACAATGTCTGATCGACCATTTTAAACTACACCTTCAGGGAGGATCAGACACAATACCCAACGAGTCTTCAATCCTCGAACCCATTGACCCAGACACgaggAAGACTTTCAGAAAAAAGAGCAGTTTtgaaaaacataaacataagGCAGTCAGCGTGAAGGAGAAGGCCGAGTGTGTGAGCAGTACAGACCCATGCGGTGCAAGTGAGACGCATAAGAAGACTTGCGTGAAAGAAGAACCTGAGTGTGGGAGCAGTGCAGAGTCATGCAGTGTAAGCGAGACGGGTGCAAGCGTCGACCACGTGATTAAGATCGAGCTGGAGCTGGGACCGGAAGGTGTACAGCGGCGCGACACACCCGTCGAGCCTCGCGAAAAATCGTGGTTTGTGGCTACAAACTACAGGCCTGCACTCGACCGCTGCGCCGTCACAGCCCACGACGAGCCCGCCGGGGCCACGGGCGCTGATCACGAAACCGTACAACATAATACAATCACCGACTCTCCGCAACACACGGCGGCAAGCAATACTTACAAGTGCGATGCCTGCgggcaaatatttatacaaaaacaATGTCTAATAGACCATGTTATAGTACACCTTCGGGAAGAACCGAAAACATTACCAAACGAGTCTTTATTCGCCCTCGAACCCAGTGTCACAGATACGAGTGTAAAGAAATATCCctgtaaaatttgtaaaaaacaGTTCCGAAAGGATTACTTAAAGATTCACGCGCGTTTACACACAGGTCAGAAACCTTATGCGTGCGAAATATGTAAAAAGCAGTTTGCTGCTCCGGGCAATTTAAGAGACCATAAACGAGTACACATCGGGGAAAGGCCTTACTCGTGTGATGTATGTGGAAAGAGTTTCGCGAGATTGGACCATTTAAAAATACACGAACGCATTCATACAGGacaaaaaccatacaaatgtgaaaTATGTAATAAGGCATTCTCGCAATTAACTAACTTACAGTCACATATAAGAACACATACTGGCGAAAACCCTTATGCCTGTACGAAGTGTGACAAGCGGTTTAGGCAATGGAGCTCTCTTAATAAACATAAAAGGTCACACACCGTTGAAAACCTATACTCGTGTGAAATAAGTAAAATGCGTTTTCAACAACCGGGTACTTTGAATGTTCATAAAATTATCCGCACGAATAAAAAGCCATTCTCGTGCGTACATAAACATGAAGCAGTCAGCGTGAAGAAGTCCGAGTGTGGGAGCAGTACCGACCCTTGCGGAGCGAGCGAGATGCATAAGGAGACTCGTGTGATGGAAGAGCTTAAATTTAGGAGCAGTGCAGACTCTTGCAGACTGAGCGAGACGTGTGCAAGCGTCGACCACGTGATTAAGGTGGAGCTGGAGCTGGGATCGGGGGGCATCAAGCGGCTCGACACTCCCTTCGCGCCTCGCGCCGCGTCACCCCGCCGCGAGTTCCTCGGGACCACGAGCGGGGCATCCGGCTCCCAACAACCTTCACCCCCGCAGGAAACCAACATGACACACGACACTCTTCAAGCGACGACCGCGGGGACACATGTCATAAAACTAAACCACGTGACCATTGACAAACAGACTAAGATCAAAAGGCCATACACCTGTGACATATGTAATaaaacattcactcaatcgggCAGCCTGAACACACACAAACGAATACACACGGGGGAGAAACCATACTCGTGTGAAATATGTAACAAAAGCTTTAAGCTGTTAGCGAGCTTGAAAACTCATGGACGAATACACACGGAAAGCAAACGATACTCCTGTGATATATGTAAAAGACAGTTCCGTTACATGAGTGCTATGCGGGTACACAACCGAATACACACGGGAGTGAAGCCGTATGTCTGTGAAATATGTAAACAACAGTTCACTAAAAAGAGCAGCGTGAATACACATATAATCCACATGCACGCAGGAGAAAAGCCGTTCTCCTGCGAAATATGTAAAAGACAGTTCGCCACCAAATGGAACTTAAAATACCATATAGGAACTCACGCAAAACATGAATCTTAG
Protein Sequence: MTFMQLGAFKTHELIHTEEKGARGELYAQGTKDELMLGPGDRQRPYRVNAFGGKIEKPESLIRDYEPALTTYREPAPTTSAEHETAQNNTFSYTMQPTHIYMCGTCGEIFQQKQYLIDHVKAHLRESSVTLLNKSSILEPSATDMSVTKYSCKICKKRFRKDYLKIHERLHTGQKAHACEVCKKQFATLGSLREHKRIHTEIRPYSCDVCTKSFVRLDHLKIHERSHTGEKPYKCETCKKAFSQLPNLQSHIRTHTGEKPYVCKTCDKQFTQWSALHNHKKTHSVEKPHSCEITTNPCAATEKYKERTRVREEPKCESRADSCSVSETGSSVNLVMKVELELGPEGVQQRDIPIAPRAAPPRCELFSCETCNKTFRKQSSFENHRHKHEAVSVKEKSESESSTDPPEASETHKETRVKEDSKCESSADSCGVSEMGANGDHVIVVEPELGPGHTQRPNIFNALGEKSRFLVRNYRPALDYCADTSHCEPAGTTDAEHDTVQHNTITETLQHTAKTQTYMCGTCGEMFLQKQCLIDHFKLHLQGGSDTIPNESSILEPIDPDTRKTFRKKSSFEKHKHKAVSVKEKAECVSSTDPCGASETHKKTCVKEEPECGSSAESCSVSETGASVDHVIKIELELGPEGVQRRDTPVEPREKSWFVATNYRPALDRCAVTAHDEPAGATGADHETVQHNTITDSPQHTAASNTYKCDACGQIFIQKQCLIDHVIVHLREEPKTLPNESLFALEPSVTDTSVKKYPCKICKKQFRKDYLKIHARLHTGQKPYACEICKKQFAAPGNLRDHKRVHIGERPYSCDVCGKSFARLDHLKIHERIHTGQKPYKCEICNKAFSQLTNLQSHIRTHTGENPYACTKCDKRFRQWSSLNKHKRSHTVENLYSCEISKMRFQQPGTLNVHKIIRTNKKPFSCVHKHEAVSVKKSECGSSTDPCGASEMHKETRVMEELKFRSSADSCRLSETCASVDHVIKVELELGSGGIKRLDTPFAPRAASPRREFLGTTSGASGSQQPSPPQETNMTHDTLQATTAGTHVIKLNHVTIDKQTKIKRPYTCDICNKTFTQSGSLNTHKRIHTGEKPYSCEICNKSFKLLASLKTHGRIHTESKRYSCDICKRQFRYMSAMRVHNRIHTGVKPYVCEICKQQFTKKSSVNTHIIHMHAGEKPFSCEICKRQFATKWNLKYHIGTHAKHES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -