Basic Information

Gene Symbol
-
Assembly
GCA_947049265.1
Location
CAMRIQ010000302.1:2577-11268[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.0016 0.13 13.9 2.9 1 23 133 155 133 155 0.99
2 14 0.0016 0.13 13.9 2.9 1 23 202 224 202 224 0.99
3 14 0.0016 0.13 13.9 2.9 1 23 271 293 271 293 0.99
4 14 0.0016 0.13 13.9 2.9 1 23 325 347 325 347 0.99
5 14 0.46 37 6.1 0.1 1 15 394 408 394 410 0.93
6 14 0.021 1.7 10.4 1.8 1 20 607 626 607 628 0.95
7 14 3.5 2.8e+02 3.4 0.1 1 13 783 795 783 797 0.91
8 14 2.9 2.4e+02 3.6 0.1 1 13 900 912 900 914 0.91
9 14 0.0016 0.13 13.9 2.9 1 23 1013 1035 1013 1035 0.99
10 14 9.4 7.7e+02 2.0 2.1 9 23 1091 1105 1089 1105 0.93
11 14 0.00027 0.022 16.3 0.6 2 23 1152 1173 1152 1173 0.97
12 14 0.061 5 8.9 6.2 1 23 1190 1212 1190 1212 0.95
13 14 2.4e-06 0.0002 22.7 0.7 1 23 1218 1240 1218 1240 0.98
14 14 1.1e-06 9.2e-05 23.8 3.1 1 23 1246 1269 1246 1269 0.98

Sequence Information

Coding Sequence
ATGTTCAACACCAAATATCATGTGCAGATGCACCTGTCCACACACCAGAAGGAGGGGCCTGTGAGTATCCAGACACCGTGGCCTGGGGACGCGAGCAGGCAAGCCGCAGAGACACATCGTCAGCCACCGGGCGGACAAGTTCGTGCTCCGGTACGAGTGTCCGGTGTGCGCGCACATGTTCAACACCAAATATCATGTGCAGATGCACCTGTCCACACACCAGAAGGAGGGCCTGTGAGTATCCAGACACCGTGGCCTGGGGACGCGAGCAGATGCACCTGTCCACACACCAGAAGGAGGGCCTGTGAGTATCCAGACACCGTGGCCTGGGGACGCGAGCAGGCAAGCCGCAGAGGACACATCGTCAGCCACCGGGCGGACAAGTTCGTGCTCCGGTACGAGTGTCCGGTGTGCGCGCACATGTTCAACACCAAATATCATGTGCAGATGCACCTGTCCACACACCAGAAGGAGGGCCTATGCACCTGTCCACACACCAGAAGGAGGGCCTGTGAGTATCCAGACACCGTGGCCTGGGGACGCGAGCAGGCAAGCCGCAGAGACCACATCGTCAGCCACCGGGCGGACAAGTTCGTGCTCCGGTACGAGTGTCCGGTGTGCGCGCACATGTTCAACACCAAATATCATGTGCAGATGCACCTGTCCACACACCAGAAGGAGGGCCTATGCACCTGTCCACACACCAGAAGGAGGGCCTGTGAGTATCCAGACACCGTGGGCCTGGGGACGCGAGCAGGCAAGCCGCAGAGACACATCGTCAGCCACCGGGCGGACAAGTTCGTGCTCCGGTACGAGTGTCCGGTGTGCGCGCACATGTTCAACACCAAATATCATGTGCAGATGCACCTGTCCACACACCAGAAGGAGGGCCTACACCGTGGCCTGGGGACGCGAGCAGGCAAGCCGCAGAGACACATCGTCAGCCACCGGGCGGACAAGTTCGTGCTCCGGTACGAGTGTCCGGTGTGCGCGCACATGTTCAACACCAAATATCATGTGCAGATGCACCTGTCCACACACCAGAAGGAGGGCCTATGCACCTGTCCACACACCAGAAGGAGGGCCTGTGAGTATCCAGGACACCGTGGCCTGGGGACGCGAGCAGGCAAGCCGCAGAGACACATCGTCAGCCACCGGGCGGACAAGTTCGTGCTCCGGTACGAGTGTCCGGTGTGCGCGCACATGTTCAACACCAAATATCATGTTGCAGATGCACCTGTCCCACACACCAGAAGGAGGGCCTGTGAGTATCCAGGACACCGTGGCCTGGGGGACGCGAGCAGGCAAGCCGCAGAGACACATCGTCAGCCACCGGGCGGACAAGTTCGTGCTCCGGTACGAGTGTCCGGTGTGCGCGCACATGTTCAACACCAAATATCATGTGCAGATGCACCTGTCCACACACCAGAAGGAGGGCCTGTGAGTATCCAGACACCGTGGCCTGGGGACGCGAGCAGGCAAGCCGCAGAGACACATCGTCAGCCACCGGGCGGACAAGTTCGTGCTCCGGTACGAGTGTCCGGTGTGGCGCGCACATGTTCAACACCAAATATCATGTGCAGATGCACCTGTCCACACACCAGAAGGAGGGCCTGTGAGTATCCAGACACCGTGGCCTGGGGACGCGAGCAGGCAAGCCGCAGAGACACATCGTCAGCCACCGGGCGGACAAATGCACCTGTCCCACACACCAGAAGGAGGGCCTGTGAGTATCCAGACACCGTGGCCTGGGGACGCGAGCAGGCAAGCCGCAGAGACCACATCGTCAGCCACCGGGCGGACAAGTTCGTGCTCCGGTACGAGTGTCCGGTGTGCGCGCACATGTTCAACACCAAATATCATGTGCAGATGCACCTGTCCCACACACCAGAAGGAGGGCCTGTGAGTATCCAGACACCGTGGCCTGGGGACGCGAGCAGGCAAGCCCGCAGAGGCACATCGTCAGCCACCGGGCGGACAAGTTCGTGCTCCGGTACGAGTGTCCGGTGTGCGCGCACATGTTCAACACCAAATATCATGTGCAGATGCACCTGTTCACACACCAGAAGGAGGGCCTGTGAGTATCCAGACACCGTGGCCTGGGGACGCGAGCAGGCAAGCCGCAGAGACACATCGTCAGCCACCGGGCGGACAAGTTCGTGCTCCGGTACGAGTGTCCGGTGTGCGCGCACATGTTCAACACCAAAATATCATGTGCAGATGCACCTGTCCACACACCAGAAGGAGGGGCCTGTGAGTATCCAGACACCGTGGCCTGGGGACGCGAGCAGGCAAAGCCGCAGAGGACACATCGTCAGCCACCGGGCGGACAAGTTCGTGCTCCGGTACGAGTGTCCGGTGTGCGCGCACATGTTCAACACCAAATTATCATGTGCAGATGCACCTGTCCACACACCAGAAGGAGGGCCTGTGAGTATCCAGACACCGTGGCCTGGGGACGCGAGCAGGCAAGCCGCAGAGGCACATCGTCAGCCACCGGGCGGACAAGTTCGTGCTCCGGTACGAGTGTCCGGTGTGCGCGCACATGTTCAACACCAAATATCATGTGCAGATGCACCTGTCCACACACCAGAAGGAGGGCCTGTGAGTATCCAGACACCGTGGCCTGGGGACGCGAGCAGGCAAGCCGCAGAGGACACATCGTCAGCCACCGGGCGGACAAGTTCGTGCTCCCGGTACGAGTGTCCGGTGTGCGCGCACATGTTCAACACCAAAATATCATGTGCAGATGCACCTGTCCACACACCAGAAGGAGGGCCTGTGAGTATCCAGACACCGTGGCCTGGGGACGCGAGCAGGCAAGCCGCAGAGGACACATCGTCAGCCACCGGGCGGACAAGTTCGTGCTCCGGTACGAGTGTCCGGTGTGCGCGCACATGTTCAAACACCAAATATCATGTGCAGATGCACCTGTCCACACACCAGAAGGAGGGCCTACACCGTGGCCTGGGGACGCGAGCAGGCAAGCCGCAGAGACACATCGTCAGCCACCGGGCGGACAAGTTCGTGCTCCGGTACGAGTGTCCGGTGTGCGCGCACATGTTCAACACCAAATATCATGTGCAGATGCACCTGTCCACACACCAGAAGGAGGGCCTATGCACCTGTCCACACACCAGAAGGAGGGCCTGTGAGTATCCAGACACCGTGGCCTGGGGACGCGAGCAGGCAAGCCGCAGAGGGACACATCGTCAGCCACCGGGCGGACAAGTTTCGTGCTCCGGTACGAGTGTCCGGTGTGCGCGCACCATGTTCAACACCAAATATCATGTGCAGATGCACCTGTCCACACACCAGAAGGAGGGCCTAATACTCGAAGAGAATCGCAACGACATCCTGGCGATGGTTCTTCAGAACGCGCGCAAGATACCCAAACAGGGCGACGCCCCAACCAACCTGGCCGACCTCATCCCCGCCGACGAGCGCAGCCGCGTGTGCAACATATGCGGCGAGGTGTTCCAACACTTCTACTACCTGGAGGAACACCTCAAGAGCCACGGCTCCCGCATCGCCATCGAGGACGAGAACAAACCCGAGGAGCGGAAGCACATCTGCCAAGTATGCAACAAGAGCTTTAAGCTCCATTACTATCTGAAACTTCACAGCTTCACGCACACCAAGGAAAAGCCCTACATATGCCAGCAGTGCGGGAAAGGGTTTATAACTAAAGGGAAACTCAAACGGCACTTGGAGACGCACTCCGGCCTGAAGAAGTACCAATGTCATATCTGCTATAAGTTCTTCACGAGGCCCAGTTATTTGAGGATTCACGTGAGGACTATACACGGCAATCAGGACTATAATTTCAGGGTGGGGAAGGAGTTTGGGATAGCGGCGCCATTGAACGCGTTGTCGGTTATGACGCAGTACAGTAATTGA
Protein Sequence
MFNTKYHVQMHLSTHQKEGPVSIQTPWPGDASRQAAETHRQPPGGQVRAPVRVSGVRAHVQHQISCADAPVHTPEGGPVSIQTPWPGDASRCTCPHTRRRACEYPDTVAWGREQASRRGHIVSHRADKFVLRYECPVCAHMFNTKYHVQMHLSTHQKEGLCTCPHTRRRACEYPDTVAWGREQASRRDHIVSHRADKFVLRYECPVCAHMFNTKYHVQMHLSTHQKEGLCTCPHTRRRACEYPDTVGLGTRAGKPQRHIVSHRADKFVLRYECPVCAHMFNTKYHVQMHLSTHQKEGLHRGLGTRAGKPQRHIVSHRADKFVLRYECPVCAHMFNTKYHVQMHLSTHQKEGLCTCPHTRRRACEYPGHRGLGTRAGKPQRHIVSHRADKFVLRYECPVCAHMFNTKYHVADAPVPHTRRRACEYPGHRGLGDASRQAAETHRQPPGGQVRAPVRVSGVRAHVQHQISCADAPVHTPEGGPVSIQTPWPGDASRQAAETHRQPPGGQVRAPVRVSGVARTCSTPNIMCRCTCPHTRRRACEYPDTVAWGREQASRRDTSSATGRTNAPVPHTRRRACEYPDTVAWGREQASRRDHIVSHRADKFVLRYECPVCAHMFNTKYHVQMHLSHTPEGGPVSIQTPWPGDASRQARRGTSSATGRTSSCSGTSVRCARTCSTPNIMCRCTCSHTRRRACEYPDTVAWGREQASRRDTSSATGRTSSCSGTSVRCARTCSTPKYHVQMHLSTHQKEGPVSIQTPWPGDASRQSRRGHIVSHRADKFVLRYECPVCAHMFNTKLSCADAPVHTPEGGPVSIQTPWPGDASRQAAEAHRQPPGGQVRAPVRVSGVRAHVQHQISCADAPVHTPEGGPVSIQTPWPGDASRQAAEDTSSATGRTSSCSRYECPVCAHMFNTKISCADAPVHTPEGGPVSIQTPWPGDASRQAAEDTSSATGRTSSCSGTSVRCARTCSNTKYHVQMHLSTHQKEGLHRGLGTRAGKPQRHIVSHRADKFVLRYECPVCAHMFNTKYHVQMHLSTHQKEGLCTCPHTRRRACEYPDTVAWGREQASRRGTHRQPPGGQVSCSGTSVRCARTMFNTKYHVQMHLSTHQKEGLILEENRNDILAMVLQNARKIPKQGDAPTNLADLIPADERSRVCNICGEVFQHFYYLEEHLKSHGSRIAIEDENKPEERKHICQVCNKSFKLHYYLKLHSFTHTKEKPYICQQCGKGFITKGKLKRHLETHSGLKKYQCHICYKFFTRPSYLRIHVRTIHGNQDYNFRVGKEFGIAAPLNALSVMTQYSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-