Basic Information

Insect: Epinotia bilunana
Gene Symbol: pol_2
Assembly: GCA_947049265.1
Location: CAMRIQ010000350.1:988716-1000851[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 9.3e-06 0.00076 20.9 6.5 1 23 320 342 320 342 0.98

2 10 0.022 1.8 10.3 1.3 1 14 348 361 348 362 0.91

3 10 0.00017 0.013 17.0 0.5 1 23 365 388 365 388 0.95

4 10 1.2e-06 0.0001 23.7 1.4 1 23 399 421 399 421 0.99

5 10 5.6e-05 0.0045 18.5 4.3 1 23 429 451 429 451 0.96

6 10 2.6e-06 0.00021 22.7 3.9 1 23 457 479 457 479 0.98

7 10 9.7e-05 0.0079 17.7 0.4 1 23 485 507 485 507 0.97

8 10 8.8e-06 0.00071 21.0 4.3 1 23 513 535 513 535 0.98

9 10 0.00022 0.018 16.6 0.7 1 23 541 563 541 563 0.97

10 10 1.8e-06 0.00014 23.2 4.6 1 23 569 592 569 592 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	9.3e-06	0.00076	20.9	6.5	1	23	320	342	320	342	0.98
2	10	0.022	1.8	10.3	1.3	1	14	348	361	348	362	0.91
3	10	0.00017	0.013	17.0	0.5	1	23	365	388	365	388	0.95
4	10	1.2e-06	0.0001	23.7	1.4	1	23	399	421	399	421	0.99
5	10	5.6e-05	0.0045	18.5	4.3	1	23	429	451	429	451	0.96
6	10	2.6e-06	0.00021	22.7	3.9	1	23	457	479	457	479	0.98
7	10	9.7e-05	0.0079	17.7	0.4	1	23	485	507	485	507	0.97
8	10	8.8e-06	0.00071	21.0	4.3	1	23	513	535	513	535	0.98
9	10	0.00022	0.018	16.6	0.7	1	23	541	563	541	563	0.97
10	10	1.8e-06	0.00014	23.2	4.6	1	23	569	592	569	592	0.98

Sequence Information

Coding Sequence: ATGGAGTTTCTTCTTTCGTGTCGCTGCTGCCTGCTGCGCCCGCCCGAGAAAGGAATCCACACGCTTTACCATCACCTCGGCAAAACTGAGATATACTCGGATATGCTGCGAGAATGCTTTGATATTCATCTGACTCTAGGCAACGACGAGTGCGGGATCTGCGAGGTGTGCGTGGCCCGGCTGCGGGACGCGAAGGACTTCAAGCAGCAGGTGCAGCGGAGCCAGGTGGAGCTGCAGTCGCGGCTGCAGGGAGCGGCTAATGCCGGGGGTAAGCCAGACAAAGCAGTATACAGAGCGCAAAAGTCGACAAATGATGCAGTTTTTGGCCTTGCTGATTATGTAACCTCTAATTTGGACCAAGGACAGAAAGCTTTAGCTATCTTCCTCGACCTTGCTAAGGCTTTTGATTCGGTGTCTGTCCCAATATTACTTAGCAAGCTGGAGCAGATAGGAATCAGGGACAAGCAGCTATGTTTGTTCAAGGATTACCTCAGCAACCGCTTGCAGTGTGTTAAGGTTGCCAACTACATAAGTGCAGACCTCATGGTCGATTTTGTAGTCCCCCAGGGTAGCATTCTGGGCCCGACCCTGTTTCTCATTTTCATTAATGACCTGCGTGACCTTCAATTGAACCATGGCTCTCTAATATCATATGCCGATGATACAGTGCTATTGTTCTCGGGTAGTAGTTGGGCGGATGTATACGACTATGCTCAGAAAGAGGAGGTCActgtcaaacaaaaaaaacttaacatcAAGCTGGAGAAAGCGTCTGGGGACGAGGCCGTCATTCGTGAAATCAAGCTGGAGAAGTCAGAAATTGAGATGGCCGATGGGGCAGTCGTGTCAGTTGCGTTATACGGCTCACCGCCGGCATCAACGCCAGCAAAGCCGACTCCAGCCGCGGAAAAGGAGTACCCCGATTCGACCCCCGCCCCCGCCGTCCGCGGCACCGTCCACACCTGCAAGATATGCCAGAAATCCTTCGATCACCAATCAGCGTTCAGAAACCACCAGCGCATGCACACAGGGGAAAAACCATTCTCGTGCAATGTCTGCCACAAGCGATTTTCACAAAAAGGGGAGAGACCATTCTTGTGCGAAGTCTGCAATAAGGCTTTCGCACTGAAAGCTACTTTACAGTCTCACTTAAAACGCAGACACGGCCATCGCGACCCGGATGAAGACTCCACCTACACATGTGAGACGTGTACCAAGCAATTCAATAAAAAGGCCGCTTTAGAAAGACACATTCGAACACACACGGGAGAGAAACAGCACAATTTCTGCTGCGAAATTTGTGGTAAACAATTCacacaaaaaaactactttTCTAAACACATGGATCTACACATCGGAAGAAGGCCGTTCATGTGTGAAATCTGCAGTAAAACTTTTACTCACAAAAGCACATTGAAAGCTCACAAATTAACACATTCTGACGAAAAACCCTTCGCCTGCAAACTATGTCCTAAACGATTCCGATTAAACAAAGGTTTGCAAGGCCACATGATGATTCACGAAGGCCTCAAACCGCACACCTGCGACGTATGCAGTAAGCAATTTAGACACAAATCCGCTCTAATGGTTCATATACGTCGCCACACAGGACAGAAACCACACTCGTGCGATATCTGTAAAAGAGAGTTCATAGTGTTAGCTGAGTTAAAGGTGCATTACCGTAGTCATACTGGAGAACAACCATATCAGTGCGAAATATGTCACAAGAAATTTGCACGTCCTGACCATTTCAGGAGGCACGTTAAACGCGTTCACAACGAGAAGCCTTCGAAGGCCGCTGCCGCGCAGCCGGTGTCTAATGCTGAATTAAGACGGTATTCGTCGCTGGCGCCGGTGGCGCTGGCGTACCAGCGCTGGCAGGGGATGGGCaatatttaa
Protein Sequence: MEFLLSCRCCLLRPPEKGIHTLYHHLGKTEIYSDMLRECFDIHLTLGNDECGICEVCVARLRDAKDFKQQVQRSQVELQSRLQGAANAGGKPDKAVYRAQKSTNDAVFGLADYVTSNLDQGQKALAIFLDLAKAFDSVSVPILLSKLEQIGIRDKQLCLFKDYLSNRLQCVKVANYISADLMVDFVVPQGSILGPTLFLIFINDLRDLQLNHGSLISYADDTVLLFSGSSWADVYDYAQKEEVTVKQKKLNIKLEKASGDEAVIREIKLEKSEIEMADGAVVSVALYGSPPASTPAKPTPAAEKEYPDSTPAPAVRGTVHTCKICQKSFDHQSAFRNHQRMHTGEKPFSCNVCHKRFSQKGERPFLCEVCNKAFALKATLQSHLKRRHGHRDPDEDSTYTCETCTKQFNKKAALERHIRTHTGEKQHNFCCEICGKQFTQKNYFSKHMDLHIGRRPFMCEICSKTFTHKSTLKAHKLTHSDEKPFACKLCPKRFRLNKGLQGHMMIHEGLKPHTCDVCSKQFRHKSALMVHIRRHTGQKPHSCDICKREFIVLAELKVHYRSHTGEQPYQCEICHKKFARPDHFRRHVKRVHNEKPSKAAAAQPVSNAELRRYSSLAPVALAYQRWQGMGNI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -