Basic Information

Insect: Ephydra gracilis
Gene Symbol: BCL11A
Assembly: GCA_001014675.1
Location: JXPQ01015978.1:13144-20802[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 2.4 2.3e+02 2.8 0.0 2 11 19 28 18 31 0.88

2 8 0.062 5.9 7.8 2.3 1 23 203 226 203 226 0.95

3 8 7.9e-07 7.5e-05 23.2 2.3 1 23 598 620 598 620 0.99

4 8 0.00095 0.089 13.5 4.5 1 23 626 648 626 648 0.99

5 8 7.5e-07 7.1e-05 23.2 3.2 2 23 876 897 875 897 0.97

6 8 9.9e-06 0.00093 19.7 3.3 1 23 903 925 903 925 0.99

7 8 2.7 2.5e+02 2.6 0.7 1 12 933 944 933 947 0.89

8 8 6.8 6.4e+02 1.4 0.0 13 22 955 964 954 964 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	2.4	2.3e+02	2.8	0.0	2	11	19	28	18	31	0.88
2	8	0.062	5.9	7.8	2.3	1	23	203	226	203	226	0.95
3	8	7.9e-07	7.5e-05	23.2	2.3	1	23	598	620	598	620	0.99
4	8	0.00095	0.089	13.5	4.5	1	23	626	648	626	648	0.99
5	8	7.5e-07	7.1e-05	23.2	3.2	2	23	876	897	875	897	0.97
6	8	9.9e-06	0.00093	19.7	3.3	1	23	903	925	903	925	0.99
7	8	2.7	2.5e+02	2.6	0.7	1	12	933	944	933	947	0.89
8	8	6.8	6.4e+02	1.4	0.0	13	22	955	964	954	964	0.88

Sequence Information

Coding Sequence: ATGACACATGACTCTGATTCAACTGAAGCGGATAGTGCCGCACTGGATATTTTAACATGCGGATTGTGTCAGAAGACCTTTGCCCTTGCAGATATTGTCAAGTTTATACAACACAAAGTTCTGCAATGCAATAAAGAAAACTACGGGCAATGTTCCACTCAAGCAACAACACATGACAGAGATTCGGAAGATGGGAGGCCGCAGAGAATCCATAATCGGCgacattcaaattcaacacaGGCAAATAGTAAAAAGCCATCAGGTTCGCGGATTCATACACCTCCTCCAAGTCCTGCTGATTTACTAGCCGATGGTGCATCTAGCACGCCCAAGCGTCTCGTAGAtgaaaatgatAATACGACTCCAAGAGATGTTGAAATGTCATCAAGAGAGGGAGTAGGAGCACAACCGGGTGGTGGTCCGTGTACAGGAAAAGATCAGgcagtaatattaaaaattaaagaggaaaaaaatacaaacgatGATGAATATAATCGCTTAACACCGAACATTTCCACCAGCTACGAGACCGAGTCCACATCAAAACGGGTGAAAGCTGATGTTGCCGATGCCGAATCAAATACTGTGCAAACagAACCTACGAATTACACATGCAGTACTTGCAAGACGCGGTACAATTCTGCTTGGAGATTGGTTCAGCATGTTCAGCATAATCATGgagtaaatatttatgttgaatgtTCATCGTACTCAAAGTCAACTGACTCTACTGCTCCGGCTTCCGTGCATTCGTTTACTTCATTATCTACGCCATCACTTTCAATGTCTTCATCATCGCTGCCAATGACTTACATAAACACAGCACCTAAAACAAATAATAGTGAGCAAAGTAGAAATAGTTCAATTTCTTCCATGTCCCCAGTAAGCAGTTCTGCGTCCAATTCAACTcagcaaaatttacaacaacaaattcagcaACAGAGAGTGGTAGCAgtagctgcagctgcagcagtaGAGCATCAAAAGCAACACCAAAATAATCTCACCGCTGCTATGCAAAACGCGCAAAgtcttgctgttgctgctgctgctggaatGAGGCACCATCCGTTACTGCCACCACCTGACATGCATTCAAATCCGTTCAATTTGCTTCGAATGCCGATACCCGCAAATCTTGGGCAAGGACAAGTCATGCCTAGCGTAGCGCCTTTATTTTCGAGGCCACACCCAGATCAATTTCGAATGGAGCAAATAGTATCGGAACAATTTCGACACCATGGATTAAATTTGGCTGCAGCTGCAGTGGCTGCAGCGAGTTCATTAGCAACTCCTCAAAGCTCCAGTTCACAATTCAATCAAAGTGGCAATATTAGTACGAATAACTGTGGCGAAACAAGAACTAGTTCCAATACCACGACTCCACAAAGGGCTTCGAACACATCTTTGGGAGTAGTAGAGCAATCAATCAACTCACTTCAAAGTACCGCGCAATCAAAGCTTCAGCAACAGACTCCTTTAAATTCGGAACCGCAATTGGATTTTTACTCTCAGCGATTGCGTCAGCTTGCAGGAACTACAAGTCCTGGAGCTGGTAATGTTGTGAACTCGAACTCGCCGAGCCCACGACAAAAGCAATCGCCTACTTTTGCGAGCCCATCACCATCACATTTACCGCCAACTCCAATCACAAACAATGCTCGAGATGCTTCACAGACACCACCAGCGAGAAGTGATTTGAAATCTACAGAAAGTAAAGACATAGTGAATTCAACTCCTCGGTCTACATCAACGCCACCGTCGAAAGTAAATCAAGAAAATACAGCGGTGTACTCATGTTCCTATTGTGATAAGAAATTCCGTTTCGAAAATAATCTCATTATACATCAACGAACGCATACTGGTGAGAAACCATATAAGTGTTCTGTATGTGAATATGAATGCTCCCATATCAATAAACTAATGAAACATATGCGCATTCATCGTAGCCCAGAAGATGGCGTTAGTAATGCCGATTCTATTGAAACAAACGAAGGAGATGAAtctgataatgatgatgataataTGGACGATGAAGCAGCAGACGAAGACGAAGATGATGTTGAAGATAATGAAGAAATTGATGACGAAGCGGAAGACTTGAGTGTAAGCAATCGGCTTGAtatcacaaattcaaaaatacaacaaacagGGCAAACATCTCTAGTTGGTGAGTTAATGGATAAATTTGGATTATCAAACATCGCCCAATATTCGGAAGCTTATAAGCAGGCATTGCAGGAGTCCAATACATTTAAGAACTTAACGCCAAAGGACAATGACAATAATAATGCAGCAAGTCCCATGCCACAACAGTTAAGTGATAAAATAAATGGCATGCCCTCAACTTTGCGTTTGCGCGAAGAGTttgcaaaaaacatatttcaacaaACATCACCAACAGATCCGACAAGTGCACAAGTACCTCTTTTTAATCCATTTCAAAATCCATTTGAATTGTCAAAACGTATTAAATTGGATGGTGGCGACTGGTGGAATATGTCTGCAATGCATCGAAATGAAGCTTTGtttgaaaatcttaaattgaAACCGCTTGGTTTGGGATCGGCGAATACAATATTGCAAAATCCATTGATGAAAAAAGAAACTAGACAGCGAAACGATACTTGTGAATTCTGTGGCAAAGTTTTTAAGAACTGTTCAAATCTTACAGTCCACCGACGTAGCCATACTGGTGAAAAACCCTATAAATGTGAGCTTTGTTCATATGCTTGTGCCCAGAGTTCAAAGCTCACAAGACACATGAAAACCCATGGCAGAACAGGCAAAGACGTTTATAGATGTCGTTTCTGTGATATGCCCTTTAGTGTACCGTNNNNNNNNNNNNNNNNNNNNNGTGTACCGTCCACACTAGAAAAACACATGAGAAAATGCGTTGTCAATCAAGGGAAAGTTTCCGCTGTTGCAAATGCTGCCAACGCAGTTACACAAGCTGCTGCACAGCAACTACAGGCACACCAGCTTTCGCCACAAACATCACTTTCATCATTTCCAGGACAATTTGCTGCAATCACAAACTGCAATGTGTCTCTGCAGAATAGTATTGACAACGACTCCAATGCCTCTGCCAGTCTCTCCTCCCATCCCATTTCATTAAAGGAAGAAGCATGA
Protein Sequence: MTHDSDSTEADSAALDILTCGLCQKTFALADIVKFIQHKVLQCNKENYGQCSTQATTHDRDSEDGRPQRIHNRRHSNSTQANSKKPSGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPRDVEMSSREGVGAQPGGGPCTGKDQAVILKIKEEKNTNDDEYNRLTPNISTSYETESTSKRVKADVADAESNTVQTEPTNYTCSTCKTRYNSAWRLVQHVQHNHGVNIYVECSSYSKSTDSTAPASVHSFTSLSTPSLSMSSSSLPMTYINTAPKTNNSEQSRNSSISSMSPVSSSASNSTQQNLQQQIQQQRVVAVAAAAAVEHQKQHQNNLTAAMQNAQSLAVAAAAGMRHHPLLPPPDMHSNPFNLLRMPIPANLGQGQVMPSVAPLFSRPHPDQFRMEQIVSEQFRHHGLNLAAAAVAAASSLATPQSSSSQFNQSGNISTNNCGETRTSSNTTTPQRASNTSLGVVEQSINSLQSTAQSKLQQQTPLNSEPQLDFYSQRLRQLAGTTSPGAGNVVNSNSPSPRQKQSPTFASPSPSHLPPTPITNNARDASQTPPARSDLKSTESKDIVNSTPRSTSTPPSKVNQENTAVYSCSYCDKKFRFENNLIIHQRTHTGEKPYKCSVCEYECSHINKLMKHMRIHRSPEDGVSNADSIETNEGDESDNDDDNMDDEAADEDEDDVEDNEEIDDEAEDLSVSNRLDITNSKIQQTGQTSLVGELMDKFGLSNIAQYSEAYKQALQESNTFKNLTPKDNDNNNAASPMPQQLSDKINGMPSTLRLREEFAKNIFQQTSPTDPTSAQVPLFNPFQNPFELSKRIKLDGGDWWNMSAMHRNEALFENLKLKPLGLGSANTILQNPLMKKETRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPXXXXXXXXVPSTLEKHMRKCVVNQGKVSAVANAANAVTQAAAQQLQAHQLSPQTSLSSFPGQFAAITNCNVSLQNSIDNDSNASASLSSHPISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -