Egra014659.1
Basic Information
- Insect
- Ephydra gracilis
- Gene Symbol
- Hivep2
- Assembly
- GCA_001014675.1
- Location
- JXPQ01032635.1:1-9370[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.0015 0.14 12.8 4.4 1 23 208 230 208 230 0.97 2 9 0.00033 0.031 14.9 2.6 1 21 236 256 236 260 0.89 3 9 0.0011 0.099 13.3 1.1 1 22 732 753 732 756 0.90 4 9 0.00016 0.015 15.9 1.0 1 22 1452 1473 1452 1473 0.96 5 9 0.85 80 4.2 0.7 11 23 1472 1484 1472 1484 0.92 6 9 5.6e-06 0.00053 20.5 5.7 1 23 1490 1514 1490 1514 0.92 7 9 0.00034 0.032 14.9 1.2 2 23 1997 2018 1996 2018 0.97 8 9 2.9e-05 0.0028 18.2 0.8 1 23 2024 2048 2024 2048 0.92 9 9 0.002 0.19 12.5 2.7 1 23 2069 2093 2069 2093 0.92
Sequence Information
- Coding Sequence
- GCTGGCAgcactaacaacaataacaacacatgTAGTATTAGCAGCACGCAGAGTGATAAACAATCAACGGATTCGCAGCGCATGAACGACACAAATGCGAATGACAGCAGTAGCTCAACGATagccaccaccaccaacaacagcTGGAACAACTCTAAATATTTGCACAAGAAATTCAAGCGTTTGGCCAGCACCAATGAGCTGGATGAGAATGTTGCTGCAACAGGTGCAGCAGATGGCGCGCCAACAGCACAACAAACGGCAGATGGCAATGAACTGCGACAGCCACAGCGCACGGCGTCATTATCATCGGCTAGCTCGATTTCACCGCCGCCCACGCAACAACAGCCAACGCAAGCGTCCACCTACAAAGTCAACAGCTTGACGAATGGTTATCAgtcacaagaacaacaacacaatCACATAGCCGAGCACAATGCCAGTAACAGAACTTCCCGTAACGACGAGCAGCAACAAACGGTCGCGCCACAGCAAATCTCGCAAAGCGATAGCAATACGTTCCGCGTGGCGGCACACAGCAACAATGTAATGCCACAGACCGAGAACGTGCACGTCATCGTCACAACGGCTAGCACAGCGAGATCTGTGACGAACGGCCGCCATGTTTGCCCCTattgcaatttgcattgcaCAAAGCCATCGGTGCTGCGGAAACACATACGCGCGCACACCAACGAGCGCCCATATCCCTGCGAAATCTGTGGCATTGCGTTCAAGACAAAGAGCAACTACTACAAGCACTGCAGATCGAACTCACACGCGGCACGCGAGCGCGGCATTGCAGTACCCACCGACGCCGATGACTGCTCATTTGGCGCCTCCGATCAAGAGGTCGATGCGGAGCTTTCCAATAGCAGCTCCGAATTGTTGAGTCGGACCGAATCGCCCATGGACGAGCGCAGCAATTTATCGCCCGCCATCGCTGCACTGCAACCACAGCCATACAGCTACAGCCAAGTCAACACACTCCCGCCAACATCGCCATCGCCTTCCACATTGTCGGCAGCAAAGACCACTTGCTTGCAACAACCTGCGCAACAACAGACACAACAGCCGCCACTGGGCTCGCCAGCGGCTGGCACACTGCCACCAACGACCGCCAGCATTGTGAGCAATACGAACACTACGCAGCGACAGCCACAGCCGCTCGACTACAAGCCATACNNNNNNNNNNCGGCGTTGTATGCCACCACGAAAGAAGCAGCTGCGGCCAAACAAACCCAAGctctgcaacagcaacaaacgcaGCAGCCTGTGCAAGTGGACAATGCAaaacagcaccagcagcagcagcagcaaagtgCNGCAGCAGCAAAGTGCGCTACAACAGTCGACGCCACCGCCAGCCGCACACATGCCACACCAGCAGCACCCCGCACAAATAAGGAATTCCTGGAGGAGCACATATCCAAGCTGATATCCCAGAATGAGGCCATCGTCGAGAATAAGGAGCTActtttgcaaaagaaatatcCGAAGGCGTTGAGCCGTTCGCGTAGCTTTACAAATTCGGCCAACGCTGCTGGTAATGCGACAGCAAATGCCAGCATGCCAGCGACgccaactgcaacaacaacaattgcacaaaacacaataaacagcaatagcaacgcTTTAGCAATGAGCAGCATGGCCAGCGCGGCTTCAACTGAGAGTGCGAATGCGAACTTGGGATCACACTCACAGCGCGATACGCACGCTGTACGCGCTACAGAGGAGAGCACCACCAACCAAACGCCACACATGCCGCCAAACGTGTTGGCACCACCGCCAACACTGAATCAGCCATATCGTCCACAGCAAAAATATGTGGGAGCACCGTTGCTGCCAGTGATTGCAACAAGCGCCGCACAATCGGCGCCCAACTCCTCAAATGTTCCGCTCAACCTGTCGGCCAAATCCAAGACCAGCTTTGCCGAAGACAATGCGCAGCTGAAGCAAACACAGCCAGCAATCGAAGCCACCAGCACACATACGCCCATTCCACGCAAGCGTCACTCTATCGAAATTAGTTGCAATGTCACCAGCACGGCTACGTCTACGAATACTACAGCCTCCGATGTGCCAGCGaagcaacagctgcagcaacaacaaaataattccattattaagaatttattgctAAACGCGCGGGGCTTGGCAGTACCCACGGGCGAAGGTGAGGACGCGGTCTACGTGTGCCCCCTTTGCAATCAAGAATTTCGCACCGCCGAAGATCTGCAGTTGCACAACAGCACCTACTGTCACGGGCTGTCGCATAGCGCACCCATAAGTCCCGCCTCGTCGCCATCGAGCATGAACAAATACCTGCGCTCCAATTCCATCTCTTGGGCGTTCTCCAAGAATCCCTTGTCATTGGCGAAGCTGGCATGGTCGCAGATCAAAACAAAACCCAGCTCGTTGGTGTTGAGTCGACTCAGCGCATCGCTGGCCAGCAGCGCTAAGGCAACGGAAACAACGACGACATCATCAACGCACTTCCTCgagcagcagccacagcaacacCAGCCATTGCAGCCGGCGCTGAAGCGCGCCAGGTACGACAGCCTAGAAGCGCCGAGGACGGACAGCTTTACGCTTTCAGCTGCAGCGTCGAAACGGCTGGGCAATAGTGGCGGCGACATGCAACCGTTGCACAACGCCAGCAAAACTTtagacagcagcagcaagcgtgACGAACGTCATAGTCGTTACTCCTCCTCTGGCGGCTGCATGATACCCATCTCCGAATGCAACGAGCTGAACAAGAGTCCCCGCACAATACGTACGCCCTTGCTGTCCGGCGGCAGCTTTCAAGAAATGTCACCAAAGCCATCGGCGGAGAAAGACTCAAGCAAGCCGAGCCATCTGATGTCCGTTATCACGACCACACCACAAATAACCCCAAAGCTGAACTTTAGCTTCAGCTCCGCTGGCACGCAGCATTTCCAGTTCCCTCCCATTAACTCAATAACCGCATTTAATCCATTGACCTTACCACCTACCGGTGTTGTTGCTGGCGAAAAAGCCATACCGTATGTGCCAGGTATACCCGGCCCCAACAATCTGATGCCAACACTGCCACCACCACAGCAGCTGCAATACCCCACGTCCATGGCCGCACGTCATTCCCTAAGTCCTAATAACTCTGTCGGTCGCAAGAATGTGGCAAGTCCTATGCTTGGTGCTGCCAACGAGTTGGCAATTAAGCCTGACCTGAAGACGACACTTTCGCCATTTGGTGGCGTGNNNNNNNNNNNNNNNNNNNNNNCACTTTCGCCATTTGGTGGCGTGCAAAATGTGCCCAGCGAGTTCAGTCGTATACCGCCTACACCCGCACAGCGCACGGCACGCCAGTGGACGACCAGCACAGTGGCGCCGTCTGTTATCACCGCGATCAAACAAACACTTGATGTGCCCAAGAAGCCGTTCAACTTCACGCGCATGGCCGAGAACGTGAGTCCCGGCAAGGCCACAAACAATCTGCAATCCAATGCGGCAGCAAGCACTGCGAAAGTGGAGAAGGAAGTGCGTCATTTTAATTTCGAGAACATAGCCAACGAGAATGAGCTGCAGATCGCTGGCAAGCCATCCAAGTTCACGCCGCTGCACGTTGACACCATGCTGACAGCAGCCCCGGGCAACGCAGTCAGTGGTGATTGCAGCACGGAAAACTCCGCAGCAGCTGCGCTGGAAGCAAAGAAATCCAAATTCTTGCGTCCCACCAGCTTGCCATTGAAACCAGGCACCTTCACGCCAAAGCGTCATCATGGCATTACACCCACCGCGAACACGCTACCGCTCATCTCACCCGAAACACCACGTCCCTCAAAAGCCTGTGTGCAGCTCTATTTGAACGGACATGCCTATACGTACCTGGGCCTCAAGAGCAGCACCAAGATGTTCTACTGCACGGTGAACTGCCCGCAGCCTTCCTATGTGGCCGGCATGCACAAGCTGTCCATGTACAGCGTGTGGCAGGTGTGCGCGGAAAATAATCCACATCCACTGGGATTCAAGCCCAAGCAGGTAATGGCGCTCTACGATTCGCGCCAAAAGACAATCGCTCAGACCATGGCAGGTGGTCGGAAGCTCGAGTACATGCTGGTCAACTCGCAGCGCACCGTAGTGACGCCATTTATAGGCGCACAGGGGCACTACTATCATCAGCAGATGAAGCGAACGGGTGTGACTGGGGAGCAACACGCTATCAAAAAGGAAGTGATCACGAGCGCAGATGGCGCCAACAGCAATGAGAGCGCCGTAAAGAAGGAGAGCGGCGCAGTCGTGCTCGTCGGTGGCTACGAGTCGCACGAAGACTACACTTACATACGTGGCCGCGGACGGGGCCGTTATGTTTGTTCGGAGTGTGGAATACGCTGCAAGAAACCGTCGAGGCTGAAGAAGCACATACGCTCNCCGTCGATGCTGAAGAAGCACATACGCTCGCACACCGATGTGCGACCATACACGTGCAAGCACTGCAATTTCAGCTTCAAAACGAAAGGGAATCTCACCAAGCACATGCAATCGAAGACGCACTTCAAGAAATGCATTGAGCTGGGCATTAATCCGGGCCCAATGCCAGCCGACGGTGAGTTCCTCGAGCCAGACGTCGAGTTTGATCAGCAGTCGACAAACTCGCAGAGCGGACCCACATCATCAGTGGCCGGCGAATCGGATAGCGACGATTCTTCTGATGACTCGGAGAGCAGTGATACGGATGAATCCAAGTCCCGCCTACAAGAGCATGAGGCAGCGCACTGTCTGATATCACTCTCAATGACGCCGCCCATTGCGCAAAGCGTGTCGCCACAGCTGAAAACGGAAACTCAAACTTTAAGCGCGACAACTGAAAACGCAACATCGCCCACAGCCGCGTCCAGCAGCTCCGCCGTTGGCATGGGCGCTAGCACGAGCGGCATTAAGCGCGTAGTATCGTTCACTTCTCCGAAGCCGCCATTTGATTACCAAAAGCAGGAGAAATATTACTCCAACCCCGAGGAATCGAAACCAAAACGTATTAGCAACACCACCGCAACAAGTTTCGAGAGTGCGCCTATCGACTTGACCAAGCCCAGGCACAGCGAACAAGCAGTGGCCACAACGTCGATGTCCACACCGTTGCCAAACCCGCCCACGAAATCGAACAGCAATGCGCCCGTGGCACTACAGACACAGGCACAAATTCACGATGTCATCTTTGGCAGCGGCAACAATGAGTCCGGCTTCATGAAGACAATGATCTCAGTGTCGGACAAGGTACGCATCTCATCGGAGACGAGCAACAAGTTGCTGGACAATGTGTTGTCGCCGTCATATGTTACAGAACAGGCCATGCAGTACAGGAAAATCAAGCAGAGCCAAATGAAATACAGCTTTGCGGTGGAAAGTACGTGCACCATGACCACGGTCAGCAACGCAAGCTCTGGAAACAGCAGCAGTTCCATTAGCACTGTCGTGGTCACCACGGCAGCTGCTGCTTTAGCAACAGCGACAACAGTATCAACTAGCAGCACTGGAAACGAAATCGCCAGATTGCCGACAACAGAGACCGCACTGCAGCCACAAGTAGTCGACGCCAACACTGTAAAGATCGAGGCGAAAACTGAACCAACAAATGCCACAACAACGACGGTGGCAGCGGCAATGGTGGGAGTGAGCACAACTAATAATCTTGCGTCCAGCGCTGGCGTCCATTGTAAATCATCCGATGAGGGCGAGGAGAGCGAATGCATGTCTGATCATGAGTCAACCAAGCAGAGCGCTACTGCAACACATACTCAGCCAAGCGGATCCAATGAAAACGTGCATAACGCCAATCTTCCCGCCGCGGTGCAGCAGCCAGGCACCACCGATTTCACAGGCGTTCTTTCGGCTCCGGCGCGCACCGTAATTGTCGGCGAGGACGGCTTCAAGAAGAGTGGCAGCAATGAAATAAAGCCAGTCTACCAGCGGCTACCAATGAGCTCCAGCGACGGTCCATCCGTGTGCACGATCTGTGCGAAAACTTTCCAGAAGCAACATCAGCTGGCGCTACACATGAACATCCATTACATGGAGCGCAAGTTTAAATGTGAGGCCTGCGGCGTTTCATTCCGCTCACAGGGCCATCTGCAGAAACACGAACGCTCGGAGGCGCACAAAAACAAAGTGATGATGACATCGACATTTGGCGTGCCAACCACATCCAACCCACGGCCATTCGAATGCACCGACTGCAAGATAGCATTCCGTATACATGGCCATCTGGCGAAGCATTTGCGCTCGAAGACGCATGTTCAGAAATTGGAATGCCTGCAGAAGCTGCCATTTGGCACGTACTCGGAGATCGAGCGAGCTGGTATCAATCTGACTGAAATCGATACCAGCGACTGTGATAACTCGTTGCTGTCGCTGCGTGCGCTGGCTGAAAAACTCAAACTGGACACGAGCATGACGAACAGTGGTGGCGCGGTGGGAGGCGCTGCAGCCAATATCACCGACACCAATTCGAATACCGGCCTGGGCTCACAGGACAGTGCCTCGGAGGATGGTTTCAGCGCAGCAGCCAGTGCGGCGGCAACGGCGATTGCATCGTTGGACAATGACAGCGCTGCCAATACGCCGAAGCGCGCCAGCAGCATCTCGGAAGACGAGGCCGTGGCGAACGCTTTAAATAACAATCTTAAGCGACGCATGCCCGGCAACTTTAGCAATGGCGAGGACAGTAACAGTCCAATGGATAGTGACAAGCGCATCCATGCCGAATCAGGCGAGCGTATGCACGTTGTGCCAGTGCCTTCATTTAAAGCCAACAGCTGCTATCACCGCAACACCCAAAACGGACACATTAGCTGGAGCGCAACGGACGCGCACATCATGCTGCCACCGAACTTACGAAGAGAGTTTAACTAA
- Protein Sequence
- AGSTNNNNNTCSISSTQSDKQSTDSQRMNDTNANDSSSSTIATTTNNSWNNSKYLHKKFKRLASTNELDENVAATGAADGAPTAQQTADGNELRQPQRTASLSSASSISPPPTQQQPTQASTYKVNSLTNGYQSQEQQHNHIAEHNASNRTSRNDEQQQTVAPQQISQSDSNTFRVAAHSNNVMPQTENVHVIVTTASTARSVTNGRHVCPYCNLHCTKPSVLRKHIRAHTNERPYPCEICGIAFKTKSNYYKHCRSNSHAARERGIAVPTDADDCSFGASDQEVDAELSNSSSELLSRTESPMDERSNLSPAIAALQPQPYSYSQVNTLPPTSPSPSTLSAAKTTCLQQPAQQQTQQPPLGSPAAGTLPPTTASIVSNTNTTQRQPQPLDYKPYXXXXALYATTKEAAAAKQTQALQQQQTQQPVQVDNAKQHQQQQQQSAAAAKCATTVDATASRTHATPAAPRTNKEFLEEHISKLISQNEAIVENKELLLQKKYPKALSRSRSFTNSANAAGNATANASMPATPTATTTIAQNTINSNSNALAMSSMASAASTESANANLGSHSQRDTHAVRATEESTTNQTPHMPPNVLAPPPTLNQPYRPQQKYVGAPLLPVIATSAAQSAPNSSNVPLNLSAKSKTSFAEDNAQLKQTQPAIEATSTHTPIPRKRHSIEISCNVTSTATSTNTTASDVPAKQQLQQQQNNSIIKNLLLNARGLAVPTGEGEDAVYVCPLCNQEFRTAEDLQLHNSTYCHGLSHSAPISPASSPSSMNKYLRSNSISWAFSKNPLSLAKLAWSQIKTKPSSLVLSRLSASLASSAKATETTTTSSTHFLEQQPQQHQPLQPALKRARYDSLEAPRTDSFTLSAAASKRLGNSGGDMQPLHNASKTLDSSSKRDERHSRYSSSGGCMIPISECNELNKSPRTIRTPLLSGGSFQEMSPKPSAEKDSSKPSHLMSVITTTPQITPKLNFSFSSAGTQHFQFPPINSITAFNPLTLPPTGVVAGEKAIPYVPGIPGPNNLMPTLPPPQQLQYPTSMAARHSLSPNNSVGRKNVASPMLGAANELAIKPDLKTTLSPFGGVXXXXXXXXLSPFGGVQNVPSEFSRIPPTPAQRTARQWTTSTVAPSVITAIKQTLDVPKKPFNFTRMAENVSPGKATNNLQSNAAASTAKVEKEVRHFNFENIANENELQIAGKPSKFTPLHVDTMLTAAPGNAVSGDCSTENSAAAALEAKKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKACVQLYLNGHAYTYLGLKSSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCAENNPHPLGFKPKQVMALYDSRQKTIAQTMAGGRKLEYMLVNSQRTVVTPFIGAQGHYYHQQMKRTGVTGEQHAIKKEVITSADGANSNESAVKKESGAVVLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSRLKKHIRSPSMLKKHIRSHTDVRPYTCKHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLEPDVEFDQQSTNSQSGPTSSVAGESDSDDSSDDSESSDTDESKSRLQEHEAAHCLISLSMTPPIAQSVSPQLKTETQTLSATTENATSPTAASSSSAVGMGASTSGIKRVVSFTSPKPPFDYQKQEKYYSNPEESKPKRISNTTATSFESAPIDLTKPRHSEQAVATTSMSTPLPNPPTKSNSNAPVALQTQAQIHDVIFGSGNNESGFMKTMISVSDKVRISSETSNKLLDNVLSPSYVTEQAMQYRKIKQSQMKYSFAVESTCTMTTVSNASSGNSSSSISTVVVTTAAAALATATTVSTSSTGNEIARLPTTETALQPQVVDANTVKIEAKTEPTNATTTTVAAAMVGVSTTNNLASSAGVHCKSSDEGEESECMSDHESTKQSATATHTQPSGSNENVHNANLPAAVQQPGTTDFTGVLSAPARTVIVGEDGFKKSGSNEIKPVYQRLPMSSSDGPSVCTICAKTFQKQHQLALHMNIHYMERKFKCEACGVSFRSQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYSEIERAGINLTEIDTSDCDNSLLSLRALAEKLKLDTSMTNSGGAVGGAAANITDTNSNTGLGSQDSASEDGFSAAASAAATAIASLDNDSAANTPKRASSISEDEAVANALNNNLKRRMPGNFSNGEDSNSPMDSDKRIHAESGERMHVVPVPSFKANSCYHRNTQNGHISWSATDAHIMLPPNLRREFN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -