Egra007494.1
Basic Information
- Insect
- Ephydra gracilis
- Gene Symbol
- -
- Assembly
- GCA_001014675.1
- Location
- JXPQ01001387.1:99327-101937[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.18 17 6.3 0.1 2 23 235 256 234 256 0.96 2 13 0.051 4.8 8.0 4.1 1 23 262 285 262 285 0.95 3 13 0.091 8.6 7.2 3.6 2 21 293 312 292 313 0.92 4 13 3.4 3.2e+02 2.3 0.1 2 10 338 346 338 351 0.79 5 13 0.0024 0.22 12.2 0.3 1 23 387 410 387 410 0.96 6 13 0.67 63 4.5 1.6 2 23 427 447 427 447 0.94 7 13 0.0093 0.87 10.4 4.9 1 23 458 480 458 481 0.95 8 13 1.3e-05 0.0013 19.3 0.3 1 23 489 512 489 512 0.97 9 13 5.1e-05 0.0048 17.5 0.2 3 23 519 539 518 539 0.97 10 13 3.5e-07 3.3e-05 24.3 1.9 2 23 545 566 544 566 0.98 11 13 0.0014 0.13 12.9 2.4 1 23 572 594 572 594 0.97 12 13 0.0013 0.12 13.1 2.1 1 23 599 621 599 621 0.93 13 13 0.057 5.4 7.9 1.3 1 23 626 650 626 650 0.97
Sequence Information
- Coding Sequence
- ATGTCGTTGCAGTGTCGCTCGTGCACTAGCACCACGGCAGCTGAGTATATTGACTTAATCTCTATATTGGATGACAATATATCCTACCTAGAATACTTCAATCAATGCACCCAATTGCATGCCGAAATAGGCGATGGCTTGCCAAGCAGCTTGTGCACTAATTGCATACATGATTTGCAAGTATCCTTTGAGTTTGTGCGTATGGCAAAGCAAGCTGATGCAGCGTTACGTGGCAATGAGCAGCTTGGTAAGGCCGCGGATGCTGAGTTGGAAATACCATTTGAGGATGGCAACGACATGCATGACACGAAAGATGAAGACACTATAATTATTGAAGAGGTCTTCCAAGATCAAATTGAAGCGCTTGAAGAGGTTGAAGAAACAGATGCAACAGAGGATATCATCGCCGAAGAATTGCTCGAAAGTGATGAAGATGACATAATTAATAACGAGCACTTAGTGGAGGATACCATAGATGTTGTGAGTTTAGAGGATCTGAATGATATGGACGACACGGAAGAGCATATTCTAGCACTGTTGGAAGAATCACCGAAAGATACGAAAGCAATTGATGCGAGCTGTGATAGAAACGATTACTTTCCCGATGACGAGGCtgataatgaatatttaattgaatttgatgacGCAGAAACAAAGATCTGCACATTAACTGATAGCGTACAACAGAAAGGCAAGAAATGGAAATGTGTTGAGTGCAAGCGTGTATTACGCGGCGATGTTTCATATGAGGGCCATATGAATATGCACAAAGATTTACGTCCATACCCATGTACACTTTGTCAATGCGCATTCCGTTGTAGAGCAAGTCTGCAGCGACATCTCTTATTAAGGCATAAAGGTAATAAAATGAGCATATCATGTTCAAtgtgcaatacaaaattaaaaactgcgaCAGACTTAAAGCAccacaaatgtaaacaaagcaaTGTAATGCCAAAAGAAGCTCATGCGAAGCAGTCGAAGGTCGTAGAATTTACCGATGGAACTGCACAGTGTCCGCATTGCGATGAAATTGTTGAGACAGCTAAGCTGCCATATCACGTGAGATGGGATCATCCAAATGAATACCGCATCGAACCGGACAAACAAAACAGAACTACAGAACTCGCTAATAATCTAGACGAGCAGAATGGCTATTATGTTTGTCAGTTTTGTGATGAGCGTTTTACGGCTTTGTTGGATATGCGAGAACATATGCGCGCAAATCATGCCGAAAAATTTGGCAAAGAGCTTAGCTTAGGCGGAGAGCCAATTGAAGAATGTAAAATATGTAAGAAGAAACTTTTGAAGCGAAATATGGCAAAACATTTAGAAAATCATGAGAATCCAACCGATCGACAGACGCCCAAGTACATATGTGCTTATTGCTCACGGgagtgtaaaaatttgaaaacgctGAACCAACATGAGAAAATGCACCATGGCGAATCGGCGGATGTTGTCTATGTTTGTGGTGAATGCaatcgacagtataatacgcaaAGTTTATTGGAGCAGCATCGTAAAATAGCGCACAAAGAACGTGATAACATATGTCCAATATGTggcaatgcttttaaattaaaaaatcagttagtaaatcatatgaaattacATTTGGAAAAGAACATCAAATGTCCACATTGTGAAAAGAAGTATGCGCGGCAATTCGATTTAAATGTGCATATGCGCACGCATACTGGCGAATTACCATTTGCTTGCCATTTGTGTGATAAACGTTTTGCCATCAAAGTGCGTTTGACTTATCATCTGCAAAAACATTATGGCGTTAAGCATGCTTGCAAGGAATGCGGTGCTgagtttaattcaaaacaaaaattgaaagcgCATTCATTTAAGCACACGGGCATGCCTTATCGCTGTGAAATGTGCAACGATCATGGATTTGCCAATCGTGATGTttttaaACGTCATCTATTGCGCGTGCACAAAGCCACAATGACAGACGATGCGCTAACGGAAATGTTCCAACGCAACACTGGGAAAACCGTAAAAATACGCACAATTGAAGAGATCGACCCTGAGCTAGTAGCTGCATCGGACATCATCGAAGAAATAATTAGCGATAATAGCATTGCGATGGAAACAGAAGCCGTTCAGTcataa
- Protein Sequence
- MSLQCRSCTSTTAAEYIDLISILDDNISYLEYFNQCTQLHAEIGDGLPSSLCTNCIHDLQVSFEFVRMAKQADAALRGNEQLGKAADAELEIPFEDGNDMHDTKDEDTIIIEEVFQDQIEALEEVEETDATEDIIAEELLESDEDDIINNEHLVEDTIDVVSLEDLNDMDDTEEHILALLEESPKDTKAIDASCDRNDYFPDDEADNEYLIEFDDAETKICTLTDSVQQKGKKWKCVECKRVLRGDVSYEGHMNMHKDLRPYPCTLCQCAFRCRASLQRHLLLRHKGNKMSISCSMCNTKLKTATDLKHHKCKQSNVMPKEAHAKQSKVVEFTDGTAQCPHCDEIVETAKLPYHVRWDHPNEYRIEPDKQNRTTELANNLDEQNGYYVCQFCDERFTALLDMREHMRANHAEKFGKELSLGGEPIEECKICKKKLLKRNMAKHLENHENPTDRQTPKYICAYCSRECKNLKTLNQHEKMHHGESADVVYVCGECNRQYNTQSLLEQHRKIAHKERDNICPICGNAFKLKNQLVNHMKLHLEKNIKCPHCEKKYARQFDLNVHMRTHTGELPFACHLCDKRFAIKVRLTYHLQKHYGVKHACKECGAEFNSKQKLKAHSFKHTGMPYRCEMCNDHGFANRDVFKRHLLRVHKATMTDDALTEMFQRNTGKTVKIRTIEEIDPELVAASDIIEEIISDNSIAMETEAVQS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -