Basic Information

Insect: Ephydra gracilis
Gene Symbol: ZFY_1
Assembly: GCA_001014675.1
Location: JXPQ01043703.1:25384-28926[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.016 1.5 9.6 0.5 2 23 25 46 24 46 0.96

2 16 0.001 0.096 13.4 1.8 1 23 52 75 52 75 0.95

3 16 0.047 4.4 8.2 0.3 2 23 79 102 78 102 0.94

4 16 0.0076 0.72 10.6 0.4 1 20 110 129 110 131 0.94

5 16 1.2e-05 0.0012 19.4 2.2 1 23 139 161 139 161 0.98

6 16 0.0081 0.76 10.6 2.7 1 23 167 189 167 189 0.97

7 16 5.4e-05 0.0051 17.4 0.6 1 23 195 217 195 217 0.95

8 16 0.22 21 6.1 4.7 2 23 646 667 645 668 0.94

9 16 0.00087 0.082 13.6 3.2 1 23 693 715 693 715 0.99

10 16 0.14 13 6.7 0.7 2 23 724 747 723 747 0.96

11 16 0.0098 0.92 10.3 5.1 2 23 752 774 751 774 0.95

12 16 0.00018 0.017 15.7 0.2 1 21 788 808 788 809 0.95

13 16 4.8e-05 0.0045 17.6 0.9 1 23 817 839 817 839 0.98

14 16 4.2e-06 0.0004 20.9 2.5 1 23 845 868 845 868 0.98

15 16 3.1e-05 0.0029 18.2 1.2 1 23 874 896 874 896 0.98

16 16 0.00017 0.016 15.8 2.2 1 23 902 924 902 924 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.016	1.5	9.6	0.5	2	23	25	46	24	46	0.96
2	16	0.001	0.096	13.4	1.8	1	23	52	75	52	75	0.95
3	16	0.047	4.4	8.2	0.3	2	23	79	102	78	102	0.94
4	16	0.0076	0.72	10.6	0.4	1	20	110	129	110	131	0.94
5	16	1.2e-05	0.0012	19.4	2.2	1	23	139	161	139	161	0.98
6	16	0.0081	0.76	10.6	2.7	1	23	167	189	167	189	0.97
7	16	5.4e-05	0.0051	17.4	0.6	1	23	195	217	195	217	0.95
8	16	0.22	21	6.1	4.7	2	23	646	667	645	668	0.94
9	16	0.00087	0.082	13.6	3.2	1	23	693	715	693	715	0.99
10	16	0.14	13	6.7	0.7	2	23	724	747	723	747	0.96
11	16	0.0098	0.92	10.3	5.1	2	23	752	774	751	774	0.95
12	16	0.00018	0.017	15.7	0.2	1	21	788	808	788	809	0.95
13	16	4.8e-05	0.0045	17.6	0.9	1	23	817	839	817	839	0.98
14	16	4.2e-06	0.0004	20.9	2.5	1	23	845	868	845	868	0.98
15	16	3.1e-05	0.0029	18.2	1.2	1	23	874	896	874	896	0.98
16	16	0.00017	0.016	15.8	2.2	1	23	902	924	902	924	0.95

Sequence Information

Coding Sequence: ATGGCTACCATAGCAAATGGCGACTCTAAAAAAATGTTGGTGCAGTTGACCACAGACGGAGTTCCAAAGTTGCATTGTCCAGTTTGTAACAAAGCATTGATATCGTTAAATGGCTACGTAAAGCATGTAAAAAAGCATGATCCGCCCGGTGGTTTCGTGTGTCGTTACTGTGATGATAGGTTTTGTTCTGAAGAAGAACTTAAGCGACATCTTAATGAAGAGCATACAACAATTGTGTGTCGTATTTGCAAACAGCTAACGTTTTCCAGTGAAATGGATTACCGAGAACACATACGTACGGTACACAATGGCATTGATCGCGAGTTGTACAAATGTAATACATGCGATGCAGAATACAAGACATATGATCCCTTCCGACGACACGTAGACACAAATTGTGGTTCAATAAAACCATTCAAATGTGATCAATGTGAAATGTCATTTGTAACCAAGTACAATCTTAAACAGCATAAGGAATCACATACTGGAAAGAGCAaattttgttgtagttattgtGGCAAAAATTTTCTGCAGAAAGGACGACTAGTGGAACATGAGCGGTCGCACACCGGAGAAAAACCATATCAATGCGATATTTGTGGAAAATCTTTTGCACATCGTGAGAGCATTGTTACACATTCATCGATACATACGGGAATACGCCTTGTAGAGTGCCGTTGCTGTGAATCACGCTTTAGTTGCCACTCGAATTTAATCAAGCATCGACGGGCAAGACCAGACACTTGCGGACAGCCTATGTACAATCCTCCCAAAAATCGTAAACGCATTCATCGCTCAAGAAtTCCAGCTACTTTAAACCCAACCTCAGAAATAAGGGTCAgcagtcaaaataaaatcattaaaccaaacgacaaaaaaaaggaaaaaaaattagtgaattataaaaaagaaaaagtgctaAATAGAAATGATagtgagcaaaaatataaacaacgaGGAAAACCTAGAAAATATGATGAAAAGAATAGTATTGTAAACGAAAATTATGAACAGGACTTTATTGCGCAGGATACCtataaaatatcagaaaaaataCGAGAGAAGAATAGCACTAGCAAAAACGTGAATGATATTGAGCAGAGAACACGAACGCAACAAGTTTCATCAGATAATAGTGATGAAAACGAAATGTACGAAGCGTTTCATGAATACGATTTGAATTCCGCGGAAGAGTTCAGCGATACCAATTCTATGGAATTTTTGTCTATAAAACCTACGGCTACAGCAAAACGTATTAAGAATGTAACTCATTCGCCACTTCATCCTATAAAAGAAGAGCATTTGGAAATTGAGTTGGAGTGTCTTGAACAACAAAATGAATTACTGTCTCGTACCTACAATACGGATTTCCAAAGTATTAAGCATGAACCGAATAAATCTgatgtggaaaattttaatgagcgtGATGTCCTACTTAGAGAACTACTCAACACAGACGATGATGAAACAGTTACCATTGTAGACCGAATGGATCGAAATAAATCAGAAACAAATACACAATTGGAAAAAACAGAGATTATTTTGGTAGATGATTGTAATGCTGCTAATTTTGATGGTGTTGAGGCAGAGGAAGAgaatgttttggaattttttcagctGCCCAAAAAATGTCGTATAATGTTGAATGACATTACAAAGCGTTTTCCACAGTTGAAAGAGCAATCATCAATGAAGGTAGATTCTACAAATTTccgaacaataaaaaatcaaccaTTCTATGCAAAAATCGAACATACTGTAGATAAGTGTGAGATTAAGAGATTAAATAAACGATATAAACACCAGGTGGAGAATTCTAGCAATGGTACGCATGAAGTTGGAGACAACGTAATTataaatactgaacataaaagATTAACTAAGCAATTGCTGAAGGCCCGTATTAAGCTACTGCAGAAAGAGCAAACTACATGGCAATGTCCACATTGCGTGAGAGTTTATCATATGCGGAAACCATTTGAAAAGCACTTGCGGGATCATCATCAGTTAAATGATGAGGAGGTTAAGAAACTATGTACAACCGATTTGGATATGGCTATGGAAAATGAAGAGATCTTTAAATGTCAtatttgtgataaaatttatatgatgaGGAAACGTTTACAGGATCATATACAAAGGCATGGGCCCAATGGCAAATTGGTCGTAAAATGCCCCTGCTATTGCAGTTTATACTTTGCAACAAAAGAAGAAGCTATTACGCATGCAAAAAAAGAACATCGGGACAAAATTTACTGTGAAATTTGTGATAAATACTGCAACGGACATGATAGCCTAAAAAATCACATGAAGCATTTGCACAGTAAAAAGGCTCCAAGCCGTAACAGCACTCAGcgcaatttcatttgtgatAAGTGTGGCAAGAAATTTCCTGGACGTACTACTCTGACAGATCATGTGAGATCCGACTGTGGACGGAAGCCATTGTACCAATGTCCCGTCTGTAGCAAACATTTTACCACAGCAGGCATACTGAAAACACATATGCTATTGCATAGCGACAATGCGCCGTTTCAATGCGATAAATGTGGTAAGAGATTCAAGGTAAAAGCGCAATACAGCACACATATAAAGACGAGACACACCGATATAAAACCTTTTAAATGTCATCTCTGCCCAAAAGCGTATCCATATAGGGAGAGTCTGCTCACTCATATGACCGTACACACAGGCATTAAACGTTTTCTGTGCAATGGTTGTGGAAAACGCTTTacttgtatttcaaatttgcaagcaCATCGCAAAGTTCATTCTGAAACTTGTGGTTTATTaccattaaatgcaaaagctaCTCAATATATGGGCGTACAAAAGGGACATTTGTTGCTTGGTGCTAAACCCGAAGCAGGTGTTGATTATAAAGaaacaaatactttaattgCAAAAGAGATAATAGATCGTGATATGCCAATAGCCGctgcaattaattttccatCCGCAGTTCACGCAGAACGTTTAGCTACAGTACCACTGCCATATCCAATTGGTAGCCTGGAAAAGCAATTGGGCAACAATAAAACCGAAGCAAGTATTGGAGCAATACCTGATACAGGTGCATCAGCAAGCcctaacgaaattttagaaattccaCAACATCTCTCCGATTTAATTGAAGACAAcccaaacaatttcaattga
Protein Sequence: MATIANGDSKKMLVQLTTDGVPKLHCPVCNKALISLNGYVKHVKKHDPPGGFVCRYCDDRFCSEEELKRHLNEEHTTIVCRICKQLTFSSEMDYREHIRTVHNGIDRELYKCNTCDAEYKTYDPFRRHVDTNCGSIKPFKCDQCEMSFVTKYNLKQHKESHTGKSKFCCSYCGKNFLQKGRLVEHERSHTGEKPYQCDICGKSFAHRESIVTHSSIHTGIRLVECRCCESRFSCHSNLIKHRRARPDTCGQPMYNPPKNRKRIHRSRIPATLNPTSEIRVSSQNKIIKPNDKKKEKKLVNYKKEKVLNRNDSEQKYKQRGKPRKYDEKNSIVNENYEQDFIAQDTYKISEKIREKNSTSKNVNDIEQRTRTQQVSSDNSDENEMYEAFHEYDLNSAEEFSDTNSMEFLSIKPTATAKRIKNVTHSPLHPIKEEHLEIELECLEQQNELLSRTYNTDFQSIKHEPNKSDVENFNERDVLLRELLNTDDDETVTIVDRMDRNKSETNTQLEKTEIILVDDCNAANFDGVEAEEENVLEFFQLPKKCRIMLNDITKRFPQLKEQSSMKVDSTNFRTIKNQPFYAKIEHTVDKCEIKRLNKRYKHQVENSSNGTHEVGDNVIINTEHKRLTKQLLKARIKLLQKEQTTWQCPHCVRVYHMRKPFEKHLRDHHQLNDEEVKKLCTTDLDMAMENEEIFKCHICDKIYMMRKRLQDHIQRHGPNGKLVVKCPCYCSLYFATKEEAITHAKKEHRDKIYCEICDKYCNGHDSLKNHMKHLHSKKAPSRNSTQRNFICDKCGKKFPGRTTLTDHVRSDCGRKPLYQCPVCSKHFTTAGILKTHMLLHSDNAPFQCDKCGKRFKVKAQYSTHIKTRHTDIKPFKCHLCPKAYPYRESLLTHMTVHTGIKRFLCNGCGKRFTCISNLQAHRKVHSETCGLLPLNAKATQYMGVQKGHLLLGAKPEAGVDYKETNTLIAKEIIDRDMPIAAAINFPSAVHAERLATVPLPYPIGSLEKQLGNNKTEASIGAIPDTGASASPNEILEIPQHLSDLIEDNPNNFN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -