Egra015820.1
Basic Information
- Insect
- Ephydra gracilis
- Gene Symbol
- zfh1
- Assembly
- GCA_001014675.1
- Location
- JXPQ01010089.1:52162-57860[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 5.5e-05 0.0052 17.4 2.2 1 23 197 220 197 220 0.97 2 15 0.0057 0.54 11.0 2.4 3 23 228 248 226 248 0.95 3 15 0.0002 0.019 15.6 0.7 1 23 396 418 396 419 0.96 4 15 0.064 6.1 7.7 0.2 2 23 425 446 424 446 0.96 5 15 1.6e-06 0.00015 22.2 2.5 1 23 476 498 476 498 0.99 6 15 0.0074 0.7 10.7 0.3 1 23 518 540 518 540 0.94 7 15 0.0072 0.68 10.7 1.9 1 23 546 569 546 569 0.97 8 15 0.23 22 6.0 0.4 5 19 580 594 577 595 0.91 9 15 0.00014 0.013 16.1 5.6 1 23 604 626 604 626 0.97 10 15 0.029 2.7 8.8 1.7 2 23 632 653 631 653 0.96 11 15 8.2e-06 0.00078 20.0 0.3 1 23 662 684 662 684 0.98 12 15 0.0042 0.39 11.5 0.2 3 23 692 712 690 712 0.97 13 15 5e-05 0.0047 17.5 0.5 1 23 718 740 718 741 0.95 14 15 0.045 4.2 8.2 0.1 1 23 751 773 751 773 0.97 15 15 0.00045 0.042 14.5 0.2 1 23 1309 1331 1309 1331 0.97
Sequence Information
- Coding Sequence
- ATGAACGGTAAATCAAATGGTATCAACTGGCTCAGACAAAATGTAatcaattctttgaaatcaaCTGTGCACATGATAATTGACTCTCAGCCGCCACAAGATGATCAGATCTTGATGAATGGCGATGCAGTTGATGCAGATGCAGCTGAAGACTTTTTAATAGCAAATGAGGCTGAAGGGAATCTAGATCAAATTGCTGctgagaatttaatttttatggcacGCGATGGGCAAATGGTGACAGAAATAATTGAAACGCGTACTGATGAAAATGGTACGGTGGTGGTATCTGCAAGCGATGGCACACCTATAGACTATGAATCAGTTTTAGGGCAGGCGGCCTTGCAGCAAGTTGTTGCAATGACATCTAATAACGCACACACCGGTACTAGTTATGTGGAGCAGTATGAAGATGATACGCCGCAAATGGTTACGGAAGAAGTCATTACTGATGATTGGGTACAATATCAAGGCGAAGAGCGAGTTGAAATATCTGCTGAGCAGATTGTTGGGTCTAGCGCGCAAGTTGTACAAGATATCGAGGTGCCTTTGCCAACGGTACAGGATGAATACACCGCATTACGTCCATATCCTTGTGATTTCTGTAGCCGTCGCTTTCGAAAAAAAACCAGTTTGATGAACCATATGCTATCCTCACACCAAAATGATAAACCGCATCTATGTAAACTCTGTGGATCCCGTTTTTTTCGACGCAATGACCTGATTAATCATTTGAAAGCACATGCGGAAAATGATCCCGTCGACGGTATGCCATATTCACATGAACTCGACCAGCCACACGACGTAAATACAAGAGTCACCAGTGATCATTATTACGATCACGATTGGCAGACAGATATGATGAACGATGACGAACTTAACACGAAGTCCAAAAAATNGATGAACGATGACGAACTTAACGCGaagtccaaaaaattgaatgcgtTGAGCGGCAACAGTTCGTCTGCCACGTCTTCAGTAAATGTGCCTAATGTAGCGCGTGGTCGTATCAGCCGACTCAAATTGAAAGATTATGTTGGACATGACACAAAACCTGAATCCAATGGCGATATGGAGTACATCGACTGCCAGCAGCTACAAGCATCTACTGCTGCAGTAAAGCTCTCAAACGATCAATCGCCAGACAATCAAAAACATTACCCAATCATCAATGACTGCAAGCCATTTGTATGCCAGCAGTGTGGGCTGGCATTTGCACGCGAGAAGGCCTTAGTCTCACATTCAAAGACTCATCACATAGAAACGCAATTGGAGTGCAATCAATGCAACGATGTGTTCTGGGATGAGCAGAGTCTACAGGAACATCAGAAAACTCACCAATTTGAAGATAGCAACTCTGAATATGATCCCGAAGAAGCCGAGGAAACGCAAAGCGAATCAGACAATGGTCAAGTGTATGCGGAGTACTATTGCAGCGAATGTGGCATATCTTTTCATAGACAGGATCTACTCAGACGGCACGAACGCACACATTTAAAAGCGAATGCGGCCATGGTGAACACATCCACTGATAGCGCAAGGGATGGACAGCATTGTTGTAATACTTGTGGTGAAACATTTGCTGAAGCATTGGATCTGCTCGCTCATGCCGAAATACACGCACGCTACCCGCCTTTCAAATGTTTACTGTGCGGTGAATCATTTTTCGAAGAACACACTATACAGCGGCATTTGCAAAGTCAACATGCCAACGAGCTGACGCCGAACAGTTGCATTTTATGCGGCAAAGAGTGTCGTGATCGGAAGGCTTTAATGAAGCATGCCTGGGATCATTCACGTGCGAAATGTCACTCATGCTCGAAATGCGGAAAGAATTTCCACAACAAAGCGCGTCTCAAGCGTCATATGGCATCGCATCGTGACAAGTCCGTGACGTGCGAGGTATGCCATGAAGAATTTCCAGATGGCAGGTCCTTGTCAAATCATCGCCACTCCCATAGCGCCAATTCAGCGGGAAAGCTGTTTCCATGCAATGAGTGTGGCAAGACGTTCGGCTCACGCAGCTCTCAGCAAATCCATGTGCGCATACATACCGGCGAGCGACCATATGGCTGTCGTTTTTGCTGGAAGGCATTTGCGGATGGCGGCACCTTGCGTAAACATGAACGCATACACACTGGCGAAAAGCCTTATGCCTGTTCGGTGTGCCCGCGCGCATTCAATCAACGTGTTGTGCTGCGCGAACACATACGTTCACATCACTCAGGGTTGGATCCTAAACGTGGCACCTATTATTGCACCGTGTGCACGGCGCAGCTGCCTAATTCGAACGATTTGATACAGCATCTCATCGAGCACAGCGACAAAAATACGGCAATGCATCGCGCGCCAGTGACTGGGCCACGTAAATATAAACGCAGACGAAAGCTTAAACCACACGAAATTGCGCATATGCGTAATGAATCTAAACAAAATGGTAATGGCATCGACATTGATATATCGGATATTGATATGGATAATGTAGACGATCTGTTGGGCATTGCAGAGAACGCCACGACTAGCACAAATATCAATGTATTGTCTAGAGGAAAAGGCACAAGAAAATATGTCGCTACTAAAGGAAAAAGAGGCAAAAGTGAAAGCGCTGATTATGATGACAATGATGAAGCAGAAGAGGATAGCGATGGAGGGACAGATCAAGGTGAGAGTGAGCTAATCGATGTAACTAATGTTGAAAGTCACTATAAAAAGCGCAACTCGTCACAACACGGTACAACTTTAATTAATGACAATAATGACAACGCGCGTCAGTTGCGCGCAAAACACGACGAAAGCACTGCACAGCGCACACATGAAGTGCAATATGTAAAAATGGATCAGACTGCCGCACGGACAAGTGCCGCCAAAACACGCAAAAAGTCTGAAAAACTTATGAAGCAAGCACGCCCGCGCATGATACACACAGAAAAGATACGCGAAGCGCCAACAAGCAGCAGCACGAGACGCCGCAGTACACGAACAGCGGCGGCCACTGCCAACATTGAACTACTCGCGGCCACCAGAAGCATTACTAATTCATCCACAATTGTTGACGACTACGAGATCATCTCTCCTGCTACACAGCCACCCAAACAAATTAGCTCTAGCCCCTTGCACATCAAGCAAGAACAGCACGATGCAGCACTGACCCAGCACAACTACTATCAGCAGCACACTGCCGTGCCAGTGCAATTAATACAAAGCATCCCGCAGCCACATCAGAGACAAGCTCATGGGTCCCCCGTGACAAGCAGTGGGCCACGCAACAGCGATTTGTATGACGCACATTTGCTGCTCGAAGCTTCGACATTACGTAAGAATatctatgaaaaattcaatccaAGCATTGTCAACGATCTGGAGGAGATTCTGGGTTCACCGATTAAAACGGACAAAATCGAACGCGAACGCTTCACCAGCGAATCGTCGACAACGCAGTTTCTAGTAGAGCAATCTGAAGAAGAAcagaatataatcaaaatagaGCCGACCTCACCAGATCTCCGCGAAATTGTCGCTGGCGGAAGTGGTGTTGACTCAAGCAATAATAATGCCACCACCAGCACGCGTCATATGCGCAGGCGAAAATACTTGGAATTCGAGAGCAGCACTGCTTCTGATagcatcatcaacaacaacaacaacaacaataacgttGCACGCAGCACAATCTCATcgtcatcaacaacaacaacagcaacattgcATTCCATGCCACAAGGTTCGACTGTCAATAGCTTTAATATGAAAAGTGCCTCCACACTGCATACCATATCAATGCCAAAGTccccaataacaacaatcagtAAAGCAGCGAACAGCGGAACCTACCATACGAGTTTTAACGATGATGCATTCGGAACGAGCAGTTCTGTCGACACCTCTTCGTATTTCTCCATTTCTGCCGAGCGCCGTCAGCGTATGTTCGAATGCGAAATGTGCTCAGCCGTGTTCAGCGATCGCGCACAGCTGCTCGATCAtgtacacatacatatataa
- Protein Sequence
- MNGKSNGINWLRQNVINSLKSTVHMIIDSQPPQDDQILMNGDAVDADAAEDFLIANEAEGNLDQIAAENLIFMARDGQMVTEIIETRTDENGTVVVSASDGTPIDYESVLGQAALQQVVAMTSNNAHTGTSYVEQYEDDTPQMVTEEVITDDWVQYQGEERVEISAEQIVGSSAQVVQDIEVPLPTVQDEYTALRPYPCDFCSRRFRKKTSLMNHMLSSHQNDKPHLCKLCGSRFFRRNDLINHLKAHAENDPVDGMPYSHELDQPHDVNTRVTSDHYYDHDWQTDMMNDDELNTKSKKXMNDDELNAKSKKLNALSGNSSSATSSVNVPNVARGRISRLKLKDYVGHDTKPESNGDMEYIDCQQLQASTAAVKLSNDQSPDNQKHYPIINDCKPFVCQQCGLAFAREKALVSHSKTHHIETQLECNQCNDVFWDEQSLQEHQKTHQFEDSNSEYDPEEAEETQSESDNGQVYAEYYCSECGISFHRQDLLRRHERTHLKANAAMVNTSTDSARDGQHCCNTCGETFAEALDLLAHAEIHARYPPFKCLLCGESFFEEHTIQRHLQSQHANELTPNSCILCGKECRDRKALMKHAWDHSRAKCHSCSKCGKNFHNKARLKRHMASHRDKSVTCEVCHEEFPDGRSLSNHRHSHSANSAGKLFPCNECGKTFGSRSSQQIHVRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDPKRGTYYCTVCTAQLPNSNDLIQHLIEHSDKNTAMHRAPVTGPRKYKRRRKLKPHEIAHMRNESKQNGNGIDIDISDIDMDNVDDLLGIAENATTSTNINVLSRGKGTRKYVATKGKRGKSESADYDDNDEAEEDSDGGTDQGESELIDVTNVESHYKKRNSSQHGTTLINDNNDNARQLRAKHDESTAQRTHEVQYVKMDQTAARTSAAKTRKKSEKLMKQARPRMIHTEKIREAPTSSSTRRRSTRTAAATANIELLAATRSITNSSTIVDDYEIISPATQPPKQISSSPLHIKQEQHDAALTQHNYYQQHTAVPVQLIQSIPQPHQRQAHGSPVTSSGPRNSDLYDAHLLLEASTLRKNIYEKFNPSIVNDLEEILGSPIKTDKIERERFTSESSTTQFLVEQSEEEQNIIKIEPTSPDLREIVAGGSGVDSSNNNATTSTRHMRRRKYLEFESSTASDSIINNNNNNNNVARSTISSSSTTTTATLHSMPQGSTVNSFNMKSASTLHTISMPKSPITTISKAANSGTYHTSFNDDAFGTSSSVDTSSYFSISAERRQRMFECEMCSAVFSDRAQLLDHVHIHI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -