Egra017024.1
Basic Information
- Insect
- Ephydra gracilis
- Gene Symbol
- -
- Assembly
- GCA_001014675.1
- Location
- JXPQ01028980.1:1-8252[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 27 4.5e-05 0.0042 17.7 0.8 2 23 255 277 254 277 0.97 2 27 0.0086 0.81 10.5 5.1 2 23 283 304 282 304 0.96 3 27 0.25 23 5.9 4.4 2 23 341 362 341 362 0.98 4 27 0.045 4.2 8.2 2.8 1 23 439 462 439 462 0.96 5 27 0.0055 0.52 11.1 2.0 1 23 469 491 469 491 0.98 6 27 0.0037 0.35 11.6 1.2 1 21 499 519 499 520 0.96 7 27 8.4e-06 0.00079 19.9 0.4 1 23 531 554 531 554 0.97 8 27 0.13 13 6.7 0.7 2 20 580 598 579 601 0.91 9 27 3.8e-05 0.0036 17.9 0.3 1 23 675 698 675 698 0.97 10 27 0.016 1.5 9.6 1.0 1 21 707 727 707 728 0.94 11 27 1.8 1.7e+02 3.2 0.2 2 23 739 761 738 761 0.93 12 27 8.4e-05 0.0079 16.8 0.4 2 23 796 817 795 817 0.97 13 27 1.7e-05 0.0016 19.0 3.9 2 23 825 846 824 847 0.94 14 27 4.5 4.2e+02 1.9 1.6 2 23 884 905 883 905 0.92 15 27 0.0015 0.14 12.9 5.7 1 23 997 1020 997 1020 0.97 16 27 0.027 2.5 8.9 1.7 1 20 1027 1046 1027 1048 0.92 17 27 0.0059 0.56 11.0 1.6 1 23 1057 1079 1057 1079 0.98 18 27 0.0068 0.64 10.8 0.5 1 23 1096 1118 1096 1118 0.98 19 27 0.00015 0.014 16.0 1.8 2 23 1126 1147 1125 1147 0.97 20 27 4 3.7e+02 2.1 0.0 2 21 1174 1194 1173 1195 0.92 21 27 0.00017 0.016 15.8 0.9 1 23 1249 1272 1249 1272 0.97 22 27 2.9 2.7e+02 2.5 0.3 2 23 1310 1332 1309 1332 0.92 23 27 0.037 3.5 8.5 6.9 1 23 1359 1382 1359 1382 0.98 24 27 3.6e-06 0.00034 21.1 0.6 1 23 1441 1463 1441 1463 0.96 25 27 0.0002 0.019 15.6 3.0 1 23 1469 1491 1469 1491 0.99 26 27 2.9 2.7e+02 2.5 0.8 12 23 1497 1508 1496 1508 0.88 27 27 4.1e-06 0.00039 20.9 3.0 1 23 1514 1536 1514 1536 0.99
Sequence Information
- Coding Sequence
- ATGTACAACGAGTGCTGTTGTCGCACATGTGAAGCAAAGTATGCGGATGATTTCATAGCGCTAGAACACTACGCCGAAAAGTTTCCGCACAAAACATTAGCTAACTTGTTACTTGATATAGCAAGAATCGATgTTGCTACTCAAAACGTATTgggcaacaaattttatttgtcgaATAAAATCTGTAAAGATTgtgcaaacaaattgcaaaatgccTATGCATTTGTTCAGCAAGCACGACGAGTTGACGAAAAATTGCACGCTCATTTGCTCGCGAACAAATCGCTTGAAAAGGTGCAAGACGAGCAGCGACTGCAAGAAACATGTTTAGAGGAATTACCCATTGATATGCCAGAGCATGATGAgtctaatataaaaatagaactGTTAAAGGAAACCGCAAATGTGGAAAATGTGACTTTTGCGGCAGAAAACAAATTGCTCGTTAACGAGCAATCAGCTGATTGTgaaaatagcagcagcagctttaAAGCTGAACAGCAGTTGAATGAAACAGGCCACTTCGAAAAACTCGAAAATGAACAAGAACAGTCGAAGCCGGAGAATGGAGCTGAAATCGatcCCATAACGGTGGGAGTTACAAACAGTATTACTGGCGTTGATGATGTTGCTATGAGCATCTCCCAGGCAGATCAGACTAGGCAGTTCGATGAAACGGAGAAAAGTGAATCTGAATGCAGGGAGGAGTTACCCAAAAAGCGTTTGAATTCAAAGCGTAAACGCGGCCGCCCAGGCAGCAAAGTGTGCACAATTTGCAATAAGAAATTTGCACTACTTGTTGAATTGCAACGGCACAGACGCACCATGCACCCGAAGGCAGCATGCCAATGTAAAATATGTGACGTTCGTTGTATGAACAAGCACGAGCTGCTGGCTCATATGCAAGAGCACGAAGGCGAAACATTCCATAGTGCTAAAATAAAACGGCAGGCGCCGACGAGCACCATTGACTGGGCATTTGGTGCGCAGCTTTACGACGCTAGGCCCATAAGACTTGCGCAATGCAATCTATGCGAATGTAAGTTCCCGAATATACGCACATTACACACACATCTATTGTCGCACGCCGCAATGGATACACTCGACGCACTCACTATGGAGAGCCTTGTCATTAAGGAGCACTTTGCGCATTGCGATGATTTGCAGCAGGTGAAAGAGCAAGTTTGTCAAGATGTGCAAGCACAGCAGTACTCAAAGTATTACACTATTACCAATCACTACGGCTATGAGATAGCCTTGAGTGATTCAGATGAGGATGGTGACGATAAGGACAAGAGCGTGCGGTTTAAGAAGTATTATTGCCAACTATGTCAAGTGTACTATGCGCGCAAGCACGAAGTGTTCACACATATGCGCGATCAGCACAAGGCTGACATTATACCATACAACTGCAATTTCTGCAAACTGGGCTTCGTTTCAGAGCGTATGTTTCGCATGCACTTGAAAACACATTgtcgcaacaaaaacaaaaagtatcaGTGCCTGAAATGTCCGGGGAAGTTCACGTATCTCGAGAATCTTACAAACCACCAATGTGCCTTGCCAAGCAACGCGCCGCCGCCGCATAAGTATAAGTGCAGCGTATGTTCCAAGTCCTATAGACGCCCAGCACTCTTGCGGGCGCATACAGAGCGCGCGCATTTGGGCAGCACGCAGGCGGCGGCAAAGGCTGCAGATTCAGCGGTTGGTAGTGCGTCGCGACCTTGTCGCAGCATTAAGTGCTGTTTGTGTACCAGCGAATTTGCAACACTTGCGGAGCTGCGCCGCCACTTGCCAATGCATGCGGACGGTGTGACGGGTTGCAATCTTAGCGAAGCGCAGTACTACAAGAATTTTTATCCCGCATTGACGTCGGACTTGAAAAATGATATCGGCACACTGATAGCGCAAGCGTATGCCACAAATCAATTGACAAAATTCTACTCGGCACTAGACGAGAGTGGCAATGAGTTGGATTTGTCCGACTCGGAAAGTGACGACGATGACACAAGCCGCAGCAGTTATGCATGCGAGTTGTGCGGCACGTCTGTTACACGACGTAAGCTTTTACGTTCGCATCAAAATACAGCGCATGCAGAGGCTATTCAAAACTTGCCGCATCGCTGCAGCACTTGTGGCTGTGGATTCGTGGCAAAcgcattgctgcagcagcatCTTCAGAAAAATTGTGCTGCCAACGTGCACAAGCAGATTAAGTGCGAACAGTGCACGGCACAATTCGTTTGGACAGAAAACTACATTAAACACTTGGAAATCAAGCATATAAACGCTAGCGGTGATATGTTGCAGCATGCTGTGACTGCTGAGAAAGGTGCAGCAGGTGTAGGTTTAGCTGAAAAGAATCATCCGCTGGCTGCAAGCATACAATGCAGTGAATGTGATAAAGTGTTCATATGGCAAAAGGATTTGGTGCGACATAAGCGCACACATCTGGCCGATACGGAGAAGCTAAAATGTCCCTTCTGCGAGCGTCGTTTCAATCGGAAGGACAATTTGCATGTACACATACGAGCTCACCATGAAGCGCTGGCGAAAATTCCTAAAAAAGAAACATCACGCTGGAATAAGGTAACCAAGTGGCAAGGTATGAACGAGAATTGGTGCAAGCCGAATGGCTGCAAGCAAATTCAGTGCATGATATGTCAGTCGAAGCACTCGAAAATATCCGATCTGCGCACACATTTGCTCATGCATCAGCAGGCTGCGGCATTAGCAACTCGTGCTGGTTTGGGGCTCAGCGAACTGAATGAGCTGCTCTTTCCAGATGAACTGCAAATGAGCAAGGAGCAGGTCGAGCAGCGCATACTGCAAGAGCTCAGGGCAGGGCAATATCAGCGTTTCTATTGCATCACAAATGAGTTTGGCTATGAAATGGGTCTCAGCAGCTCAGAGACTGATTCCGATTCGGATGAGGATAGCGCGGTGAAAGCGGAAGACTCACTGGCTGCGGGCgcaggcaaacatttttatcgCTGCGAGCTATGCAACGCTTGCTACAGGCGAAAGTATTTGCTGTATCGCCATCAGCATAGCGCGCATAAGTGGCAGGAGGCGCCACACGCCTGTACGCAGTGTCAGGCGCGGTTTGTCAGCACTTCACTGCTGCAGCATCACTATACcaggcaatgcaaaaataatgagaaGCGTTTTACGTGCCGGAAGTGTCCGCTAAAGTTTATGTGGCAGGAGAACCTAAAAACGCACATGCAACAGCATGCCGAAAAGCAGGCCCATCAGAAAAGCGCTCAAATGGCGGGCAACGCCTACGAGTGCGCACAGTGCAGCCGCAGCTTTCTCATGCTCAAAGATCTCACTCGGCACATGGTGATGCACAATAGCAACGCATACACTCTGAAGTGTCATTGGTGTCCGCGTAAATTCTATCGCGAGGCCAACCTGCTGATGCACGTCAAGCGGCATGGCATACCAGCGGACAGTTTGGATTACGCAGAGAGCATGATTAGCTGCTATTACAATGCACATGGTAAGAAGGTGATCGAGTGCAAAGTGTGCACCGCAAAGCAGTTCGCTAGCATTGGCCTATTGCGATTACATCTGCAGCAAGAGTGCTGCGCTGCTGTGGCCGCGCGGACACATCACAGCTACGATTCCATGCTGAATTACTCTATACGGAATGCGCAGGGCTTTGAGTTGGCGCTTGATGACTCAGACACTGAAGATGAACTCGATGTCAGCCTTTGCTCGACATTTGGACGCAGGCAGTACAACTGTGAGGTTTGCCAGCTCAGCTTCAAACGCAAATACCAAATCGCACAGCATCAACAATCGGTGCACAAGTACGAAGCTCTGCCATTGCAGTGCCACCGCTGTGTCTTCAAAACAGTCTGCATgGATGTGCTGGCGTATCATATGCGCACACAGTGCTACAACGAGGAGAAATGTCTAAGCTGCAAAATGTGTTCGTTTAAATATATGTGGCAGGAGAATCTGGATGTGCACATTCAGCTGCAACATGCCGCCGACGATGCCACCAGTAGCAGCACACAAAACACAACGCCTAAAGTGAGAAAGTTGAAAAGTACTCGGGGTGAATTCAGCTGTGAGCTGTGTAGTTGCAAGTACAAGCAAAAGCATCGTCTGGCCGAGCATATGAGGCGTTTTCATGCAACGGCCATGGTTGCTGTGAGCACGACGACNACGACGACGACGGCGACAGCCGGTAAAATCTCAATAATACCGCTGACAAACTCAACGATGTCACCAACGCCGAGCAAGCAGTACCCATTGCAAAGTGGTAGCTATACTGCCGAACCACCGACCAAGAAGCTGGACAAAAAATTCCTGTGCACTTTTTGTGGCAAAGCACTCACGTCGTCGTCCAATTTAGTTATACACATGCGACGGCACACCGGTGAGAAGCCATTTAAATGCGAGTTTTGCGATATGGCATTTCCACGTTCCTCCGATCTGCAGTGCCATCGGCGCACACACACCGGCGAGAAGCCGCACAAGTGCACCTTGCAACAGCACATGCGTATACATTCGGGCGAACGACCCTACAAGTGCACATATTGCGAGAAGAGTTTTACGCAGAAGAACGACATGACACTGCACGTGCGCCGGCACACAGGCGAGAGGCCCTATATTTGCAGTGTATGCG
- Protein Sequence
- MYNECCCRTCEAKYADDFIALEHYAEKFPHKTLANLLLDIARIDVATQNVLGNKFYLSNKICKDCANKLQNAYAFVQQARRVDEKLHAHLLANKSLEKVQDEQRLQETCLEELPIDMPEHDESNIKIELLKETANVENVTFAAENKLLVNEQSADCENSSSSFKAEQQLNETGHFEKLENEQEQSKPENGAEIDPITVGVTNSITGVDDVAMSISQADQTRQFDETEKSESECREELPKKRLNSKRKRGRPGSKVCTICNKKFALLVELQRHRRTMHPKAACQCKICDVRCMNKHELLAHMQEHEGETFHSAKIKRQAPTSTIDWAFGAQLYDARPIRLAQCNLCECKFPNIRTLHTHLLSHAAMDTLDALTMESLVIKEHFAHCDDLQQVKEQVCQDVQAQQYSKYYTITNHYGYEIALSDSDEDGDDKDKSVRFKKYYCQLCQVYYARKHEVFTHMRDQHKADIIPYNCNFCKLGFVSERMFRMHLKTHCRNKNKKYQCLKCPGKFTYLENLTNHQCALPSNAPPPHKYKCSVCSKSYRRPALLRAHTERAHLGSTQAAAKAADSAVGSASRPCRSIKCCLCTSEFATLAELRRHLPMHADGVTGCNLSEAQYYKNFYPALTSDLKNDIGTLIAQAYATNQLTKFYSALDESGNELDLSDSESDDDDTSRSSYACELCGTSVTRRKLLRSHQNTAHAEAIQNLPHRCSTCGCGFVANALLQQHLQKNCAANVHKQIKCEQCTAQFVWTENYIKHLEIKHINASGDMLQHAVTAEKGAAGVGLAEKNHPLAASIQCSECDKVFIWQKDLVRHKRTHLADTEKLKCPFCERRFNRKDNLHVHIRAHHEALAKIPKKETSRWNKVTKWQGMNENWCKPNGCKQIQCMICQSKHSKISDLRTHLLMHQQAAALATRAGLGLSELNELLFPDELQMSKEQVEQRILQELRAGQYQRFYCITNEFGYEMGLSSSETDSDSDEDSAVKAEDSLAAGAGKHFYRCELCNACYRRKYLLYRHQHSAHKWQEAPHACTQCQARFVSTSLLQHHYTRQCKNNEKRFTCRKCPLKFMWQENLKTHMQQHAEKQAHQKSAQMAGNAYECAQCSRSFLMLKDLTRHMVMHNSNAYTLKCHWCPRKFYREANLLMHVKRHGIPADSLDYAESMISCYYNAHGKKVIECKVCTAKQFASIGLLRLHLQQECCAAVAARTHHSYDSMLNYSIRNAQGFELALDDSDTEDELDVSLCSTFGRRQYNCEVCQLSFKRKYQIAQHQQSVHKYEALPLQCHRCVFKTVCMDVLAYHMRTQCYNEEKCLSCKMCSFKYMWQENLDVHIQLQHAADDATSSSTQNTTPKVRKLKSTRGEFSCELCSCKYKQKHRLAEHMRRFHATAMVAVSTTTTTTTATAGKISIIPLTNSTMSPTPSKQYPLQSGSYTAEPPTKKLDKKFLCTFCGKALTSSSNLVIHMRRHTGEKPFKCEFCDMAFPRSSDLQCHRRTHTGEKPHKCTLQQHMRIHSGERPYKCTYCEKSFTQKNDMTLHVRRHTGERPYICSVC
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -