Egra010675.1
Basic Information
- Insect
- Ephydra gracilis
- Gene Symbol
- -
- Assembly
- GCA_001014675.1
- Location
- JXPQ01029332.1:2754-5721[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.53 50 4.9 4.4 1 23 34 56 34 56 0.97 2 15 1e-05 0.00098 19.6 2.6 1 23 217 239 217 239 0.97 3 15 4.9e-06 0.00046 20.7 5.2 1 23 245 267 245 267 0.98 4 15 7.5e-06 0.00071 20.1 3.2 1 23 273 295 273 295 0.97 5 15 3.6e-06 0.00034 21.1 1.9 1 23 301 323 301 323 0.98 6 15 0.00013 0.012 16.3 0.8 1 23 329 351 329 351 0.97 7 15 0.23 22 6.0 0.3 1 14 357 370 357 374 0.89 8 15 0.0061 0.57 11.0 3.5 1 23 470 492 470 492 0.95 9 15 1.4e-05 0.0013 19.3 3.2 1 23 648 670 648 670 0.97 10 15 1.9e-06 0.00017 22.0 1.6 1 23 676 698 676 698 0.98 11 15 3.2e-07 3e-05 24.4 3.6 1 23 704 726 704 726 0.98 12 15 1.8e-06 0.00017 22.0 1.4 1 23 732 754 732 754 0.98 13 15 2.8e-06 0.00026 21.5 0.3 1 23 760 782 760 782 0.98 14 15 0.011 1 10.2 4.1 1 23 788 810 788 810 0.98 15 15 1.9e-05 0.0018 18.8 1.4 1 23 816 839 816 839 0.98
Sequence Information
- Coding Sequence
- atgAAAAATCCCTCTAGTGCACTTCAGATTTCGCATCGGACGGAAGATAGCATTAGCTGCGGAGAAATCATATTGATTAAGAATGCATGGCGTGTCCAATTTCAATGTGTGCACTgtcatatgaatataaaaaatttggaactgTTTTTGCGGCACTCACTTAAGCACATTTACGATATAAGTGAGGATGATGTGAAAAACCAGAAAGTGGCAAAGTTTCTAGCAACCAACGCTAACGAGCAGGAAACCGAAAAGCTATTGAATCTTGAAGGCATGGAATGGTTGATTTCGAATGGAGATCCATTGGCGAATATTAAAACAGAGGAAATTAATATTGTCGATACATGTTATGATAGTCCATTGGAAACCTGTACAATATCGAAGCATGACTCGCCCATTGACGCACACCGGCTGAATGATGAGCATAAGAACGAAGCTATTCGCGAACATTCTGTGCATTTAGAATCTGAAGTTTCACAGTATATCATGCGAGAAGAGCAGATTATGAAACTAGCTGATGATTCCGaatttcgaattaataatttacaagcGGCATTTGTTGAGGCAAACAAAAGGCACACAGATCTGTCAGTAGATAGCAATAAGCCCAAGAGCGGAGTGAAAGTGAAGCAAAATAaagacaaacaatttatttgcccgatttgcaacaaacaatttaaagtaaagCATCATTTAAGTGCTCACCTAATAAGTCATAGCAGTGATAAACCGCACAAGTGTGACATGTGTGATGCTTGTTTTAAGGACCGTTCAAATCTGAACGCTCATCGCAAACGGCATTTAAGCATAAAACCCCACCAATGTGAACTGTGTGATAAGCGTTTCCCGTCGAAAACCGAATTGAGAACGCATCTCCGATTTCATACAGGTGAAAAGCCTTATGTGTGTGAAAAATGCGGCGCTGCGTACAAAACGAGTTCGCACTtggcaaaacataaaaagcgGCATACAGAAGTCCGCTCCCACGTCTGTGGCGAATGTGGCATGCAATTTTATGATAATGTGctcttaaaaaatcataaattgacGCACAGTCATGAAAGGCCATTTAAATGTGAAGTTTGCACTGCGgcttttaaaaccaaaaatgGCATCCAGCACAATACAGTGCACGCAACATACAAAAACGGGAAACCAAAACAAACACGTCGCGAGAGTTTGGCAGCACTGGAGCCATATGACATTGATTTTAGATATTGCTCTCCGCAGGCAAACACAATGAATAGAACAACAAATagtaattttggtttaaaatataaatttgaaagttttgaaaaccCGAGCAATGACTCGATGCCTGCTGATACTGTTCCTGGTGCATATTTGACAGAAGAAAGCATTGGCTGCGGCGAAATTATATTGATGAAAAATGCATGGCGtatgcaatttcaatgcaaatattgtcaaaaatgtgtaaataatttgGAACTATTTTTGCGGCACTCACTTGAACACATATATGATATCAGTGAGGAGGATGCTAAAATCCAAAAAGTGGCTAAGTTTTTAACAACAAACGCAACTGAACTGGACACCGAGAAGTTATTAACGTTAGATGGCGTAGAATGGGCGATTGCGAGTGCAGATCCCATTGCCAATATCAAAACAGAAGAGATAAATATCGTGGATGAATATGACAATGACGAGCAGTTTAAAAATTCTGATTCATTGGAGTTTAACCCAATTGCTGATGTGCATGATAGAACGAACGAAAGTCCAATGCATGTTGTTGCTAAAGAGGATAAATTAAATCTTAGCAAAGTTACGCAGTATCAAATGATTGTACAAAATAACGCGCCAGCCGATGACATCAACTGTAACACGAATAAAGATCGTACAAACTTTTTGGTcgcaaattcaaaatcaaaattaggcAATAAAACAGCAGCGTTAGTTaccaaacaaaagcaacaaagacCGTTTATTTGTGAGTTATGCCAAAAGCAATTCAATACCAAGATGCACCTTAAAAGACACATTGTTACTCACGGTAGTGATAGACCACACAAGTGTGATATATGTGAAGCTAGTTTTAAGGACCGCGGCAATTTGAACGTACACCGCCGGCGACATTTAGGCATTCAGCCACATCAATGTTCTGAATGTGATAAGCGCTTCACAACATCCACAGAGTTAAAAATACATCAACGTTCGCATACGGGTGAGAAGCCGTTTGTATGTGACCACTGTGGTGCTACATACTCGACGAGCTCACGTCTACAGGATCACATACGAAGGCATACAAATGTACGCTCCTATGTCTGTGGAGAGTGCGGCAAACAGTTTTACAATAAGGCGCTGCTAAATGATCATCTAACAACGCACAGCGAAGCAAGACCGTTCACATGCGAGGATTGCAGTGCGTCGTTTAAGTGTAAGAAAGCATTGAGACAGCACAGAAAACTGCACATGAATCTCTTTGAATATAAATGTTCATATTGCGAAAAGgcatttcaacaaaatgctGGCTTGCACTCTCATATCAAGAGCGTgcatggcaaaataaaataa
- Protein Sequence
- MKNPSSALQISHRTEDSISCGEIILIKNAWRVQFQCVHCHMNIKNLELFLRHSLKHIYDISEDDVKNQKVAKFLATNANEQETEKLLNLEGMEWLISNGDPLANIKTEEINIVDTCYDSPLETCTISKHDSPIDAHRLNDEHKNEAIREHSVHLESEVSQYIMREEQIMKLADDSEFRINNLQAAFVEANKRHTDLSVDSNKPKSGVKVKQNKDKQFICPICNKQFKVKHHLSAHLISHSSDKPHKCDMCDACFKDRSNLNAHRKRHLSIKPHQCELCDKRFPSKTELRTHLRFHTGEKPYVCEKCGAAYKTSSHLAKHKKRHTEVRSHVCGECGMQFYDNVLLKNHKLTHSHERPFKCEVCTAAFKTKNGIQHNTVHATYKNGKPKQTRRESLAALEPYDIDFRYCSPQANTMNRTTNSNFGLKYKFESFENPSNDSMPADTVPGAYLTEESIGCGEIILMKNAWRMQFQCKYCQKCVNNLELFLRHSLEHIYDISEEDAKIQKVAKFLTTNATELDTEKLLTLDGVEWAIASADPIANIKTEEINIVDEYDNDEQFKNSDSLEFNPIADVHDRTNESPMHVVAKEDKLNLSKVTQYQMIVQNNAPADDINCNTNKDRTNFLVANSKSKLGNKTAALVTKQKQQRPFICELCQKQFNTKMHLKRHIVTHGSDRPHKCDICEASFKDRGNLNVHRRRHLGIQPHQCSECDKRFTTSTELKIHQRSHTGEKPFVCDHCGATYSTSSRLQDHIRRHTNVRSYVCGECGKQFYNKALLNDHLTTHSEARPFTCEDCSASFKCKKALRQHRKLHMNLFEYKCSYCEKAFQQNAGLHSHIKSVHGKIK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -