Egra011653.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ephydra gracilis
Gene Symbol
-
Assembly
GCA_001014675.1
Location
JXPQ01025679.1:78351-83605[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 9.2e-06 0.00086 19.8 2.4 1 23 207 229 207 229 0.98
2 18 5.8e-05 0.0054 17.3 0.4 1 23 235 257 235 257 0.97
3 18 2.5e-05 0.0023 18.5 0.6 1 23 263 285 263 285 0.98
4 18 1.1e-05 0.001 19.6 3.1 1 23 291 313 291 313 0.97
5 18 2.5e-05 0.0023 18.5 4.7 1 23 319 341 319 341 0.99
6 18 2e-05 0.0019 18.7 5.2 1 23 347 369 347 369 0.97
7 18 2.1e-07 2e-05 25.0 4.3 1 23 375 397 375 397 0.98
8 18 7.9e-08 7.4e-06 26.3 2.4 1 23 403 425 403 425 0.97
9 18 4.6e-05 0.0043 17.6 6.7 1 23 431 453 431 453 0.97
10 18 1.3e-05 0.0012 19.3 6.5 1 23 459 481 459 481 0.98
11 18 2.2e-06 0.00021 21.8 4.5 1 23 487 509 487 509 0.98
12 18 5.2e-06 0.00049 20.6 8.1 1 23 515 537 515 537 0.98
13 18 1.3e-06 0.00012 22.5 7.7 1 23 543 565 543 565 0.98
14 18 4.7e-07 4.4e-05 23.9 7.7 1 23 571 593 571 593 0.98
15 18 0.00015 0.014 16.0 9.5 1 23 599 622 599 622 0.95
16 18 0.00012 0.012 16.3 0.5 1 23 628 650 628 650 0.97
17 18 0.029 2.7 8.8 2.4 1 20 660 679 660 679 0.97
18 18 0.084 7.9 7.4 0.1 10 23 681 695 680 695 0.90

Sequence Information

Coding Sequence
ATGCAACATGTTAATGCGCTAACATCATCAACGGCGAGTGGCAGTACATTAGCTTTGAGTACACCAAAAACCGAAGCAAAGGAAGATGCAAATGCGAAGCCACCACATGGAATTGAAATGTATAAAGTTAATATAGAAGATATTTCACAATTGTTTACATATCACGAGGTATTCGGTAGAATACATGGTGATGTAATGAATCATCATTTAGCAGCAGCACACGTGATGCAACCGACACAAAGTACATCATTACCTACAACAGCTAGCGGTGTCAATACATCAGTGGCCGCTGCGATGGCATCAGCCAATGCAGCTGCAGCAATCGTTGCAGCTTCACAATCAGCAACATCAGTCGCTACAACATCAGAGGCATCAGCAGTTGTACCAGATAATGTGACAAACACAACATCAAGTATTGTACCCATTACAAgcacaaatttaacaacatccataagcacaacaacaaatgccactTCTGCAGTCACCACGACCGCAACTAATAACATAACGAAAATCGAATGgaaattaccaaaaatggaAGGTGGCATTAGCATTGGTGACCAAAATTCGACACCAATTACACTAGCGCCAGATGGTACACCAATCGCTACTGGGACACATACATGTGATATTTGTGGGAAAGTATTTCAATTTCGCTATCAGCTTATTGTACATCGGCGCTATCACAGTGAACGCAAACCCTTCAACTGTCAAGTATGCGGCCAAGGTTTTCAAACATCGCAAGACTTAACACGCCATGGGAAAATACACATTGGGGGACCAATGTTTACGTGCTTAGTTTGTTTTAATGTCTTCGCAAATAATGCTAGCTTAGAGCGTCATATGAAAAGGCACTCCACAGACAAGCCTTTTGCTTGTACAATATGCCAAAAGACTTTTGCCCGTAAGGAACATTTGGATAATCATTTTCGCTCACATACCGGCGAAACACCATTCCGTTGCCAGTATTGTGCGAAAACATTCACACGCAAAGAACATATGGTAAATCATGTTCGAAAGCATACTGGCGAGACTCCACATCGCTGCGACATTTGCAATAAATCATTTACACGCAAGGAACACTATGTAAATCACTACATGTGGCATACCGGACAAACACCACATCAGTGTGAAGTTTGTGGCAAAAAGTATACTAGAAAGGAACATTTGGCTAATCATATGCGTTCTCATACTAATGATACACCATTTCGTTGTGAAATTTGTGGTAAGAGTTTTAGCCGAAAGGAGCATTTCACCAACCATATTCTCTGGCATACAGGTGAAACACCTCATCGTTGTGACTTCTGCTCAAAGACATTCACACGGAAAGAACATTTACTCAATCACGTCCGGCAGCATACTGGTGAATCTCCGCATCGTTGCACATATTGTCTAAAAACTTTTACGCGCAAAGAACACCTTGTCAATCATATACGCCAGCACACCGGCGAAACACCATTCAAATGTACATACTGTACAAAAGCTTTCACACGAAAAGACCACATGGTAAATCATATACGGCAGCATACAGGTGAATCACCCCATAAATGTACATATTGTACGAAAACATTTACGCGTAAAGAACACTTGACTAACCATGTGCGGCAGCATACTGGTGAGTCCCCACATCGGTGCAGTTATTGCAAGAAAACGTTCACACGGAAAGAGCACCTAACAAACCATATACGTTTACACACTGGTGATTCTCCGCACAAATGCGAATATTGTCAAAAGACATTTACACGCAAGGAACATTTAAACAATCACATGCGGCAGCATTCAAGTGACAATCCGCATTGTTGCAATGTTTGTAATAAGCCCTTTACGCGTAAGGAACATTTAATAAATCACATGTCAAGATGTCATACTGGGGATCGGCCATTTGCATGTGAAACTTGCGGTAAATCATTTCCTCTCAAAGGCAATTTATTATTCCATCAGCGTAGTCACACAAAGGGACAAGATGTGGAAAGACCATTTTCATGTGAGAAATGCCCaaagaatttcatttgtaaaGgACATTTGGTTTCACATATGCCATTTGTGGAGCGTGGCAATTTAAAAAGACACATGAAAATGAATCATCCAAATGCAATCGTACCACCGCTACCACCAGTACCACATCCACAAATCCCAGCAGGAGTTGTTACGCAAATTAAACAAGAACTCAAACCGATACTAATTCCACAACAAGGAACGACCATGCATACAATACAACAAATAACTAGTGGTGTAGCAGCAAACAGCGGAAATACGATGCAATTAACAACAGGCTTGcagcaaacaccAACAGTGCCCATCGCTTTAATCCAATCTGATCCAAACGTAATACCACGTACAACAATTCAATTGCAACATTTGCCCCCTAATGTCGATCAGCATCCTGTCGTATATTAA
Protein Sequence
MQHVNALTSSTASGSTLALSTPKTEAKEDANAKPPHGIEMYKVNIEDISQLFTYHEVFGRIHGDVMNHHLAAAHVMQPTQSTSLPTTASGVNTSVAAAMASANAAAAIVAASQSATSVATTSEASAVVPDNVTNTTSSIVPITSTNLTTSISTTTNATSAVTTTATNNITKIEWKLPKMEGGISIGDQNSTPITLAPDGTPIATGTHTCDICGKVFQFRYQLIVHRRYHSERKPFNCQVCGQGFQTSQDLTRHGKIHIGGPMFTCLVCFNVFANNASLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICNKSFTRKEHYVNHYMWHTGQTPHQCEVCGKKYTRKEHLANHMRSHTNDTPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCTYCLKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHIRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGESPHRCSYCKKTFTRKEHLTNHIRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFACETCGKSFPLKGNLLFHQRSHTKGQDVERPFSCEKCPKNFICKGHLVSHMPFVERGNLKRHMKMNHPNAIVPPLPPVPHPQIPAGVVTQIKQELKPILIPQQGTTMHTIQQITSGVAANSGNTMQLTTGLQQTPTVPIALIQSDPNVIPRTTIQLQHLPPNVDQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-