Eman013893.1
Basic Information
- Insect
- Ephialtes manifestator
- Gene Symbol
- HIVEP2
- Assembly
- GCA_963970395.1
- Location
- OZ019970.1:30334029-30344302[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 8.2e-05 0.016 17.1 0.6 1 23 97 119 97 119 0.98 2 9 0.025 4.7 9.3 2.1 1 21 125 145 125 149 0.86 3 9 0.0037 0.7 11.9 0.0 2 21 357 376 356 377 0.94 4 9 1.8e-06 0.00035 22.3 1.6 1 23 1139 1161 1139 1161 0.99 5 9 2e-05 0.0039 19.0 4.3 1 23 1167 1191 1167 1191 0.92 6 9 2.5e-06 0.00048 21.8 0.1 2 23 1900 1921 1899 1921 0.97 7 9 0.00099 0.19 13.7 1.8 1 23 1927 1951 1927 1951 0.92 8 9 0.0017 0.32 12.9 3.3 1 23 1972 1996 1972 1996 0.93 9 9 0.32 61 5.8 0.8 1 19 2155 2173 2155 2178 0.94
Sequence Information
- Coding Sequence
- ATGACTGATCCACAGTTGAcgaacaacaataacaacaacaataacaataacaacaacaacaacgatGGAGAACCAAAGTATCTTCACAAAAAGTTCAAGAAGATGGCAACGACAGAGGCGGCACCGGTGGAAAACAAACAAGCTACCACCGCCAATACCACTGGACCGTCTAACGACGTGCCGAAGAAAAAAGATGTTGGTAAAGACGTTAAGGACGTTAAAGAGTCTTCCAGGGCTGAGGCCTCGCCTGAATCCGAAGGCGAACCTACCGAGGCTCGAAAAGCTGGATATGTATGTCCGTACTGCAAACTCTCATGTGCCAAGCCGAGCGTTCTTCAGAAACACATCAGGGCTCACACGAACGAGAGACCCTATCCCTGCGTGCCATGCGGTTTCGCTTTTAAAACGAAATCGAATCTTTATAAACACTGTAGATCACGAGCTCATGCACTCAAGATGGAAGGCGGTGATGCTAGTAAGGTCTCCGAGGATTCGGATATAAGTCTTTCTGACAGCGCAAGCAATGGAACGGGTACTCCACCGCCGCCACCCGCCACATCCACGCCAAGTTCCGTGCCAAGTACAAAGACTGTGAAAACAGGTAAAATCTACAAGCCAAAGTTTCACACGGCGCTTCAATGCGTGAACAATGAGCCCGAAGTATCACCTGTAACGTCGAGTTCGTCAAACGGTTCAGGAGCGACGACTACaacgacaacaacaacaacggTAGCAACGAGTCTTAAACCAAACGCGGAACAGCTTCAGGAGCATATAGACAAGATAATAACGGACAATCAAGCGATAGTCGAAGCAGTGGATCCGCGTCTTCATAAGCTAATGCAGAGGCAGCAAAGTCTCGTGGAGCCAAAGCACACAGAGCAGCCTTTGAATCTCTCGTCAGCAGAGGAGGCATCATCAAGAAAACGCTGTTATAGCGAGAGCTTCGCACAGGAGAATCGCGGTCTGGTGCAAAATCCCGAAGGCTCGATAATCAAGGATCTTTTATTAAAGAGCCGTGGCATTAACTCGGACGACACAATAACAACTCAAGAAAGTGAAAATTTGGTGTGTCCTTCGTGCAAAATTCCTTATACAAGCGCCGACAATTTGGAGGCACATAGAAGATATTATTGCAAAGGCGCGTCGCCGAGTCCCAGACGCGCTGACTTCCAGTTGGATCTCGACAAACGCGACGATTACGATAACGTTAAATCGTCTGATTATTACGGAGCAATTCAACCTCTTCCCTCGCCAGGTCCTCTCCTCGGTAACACGAGATTGGTCGACGCTTACACTCCACCGACGAAAAAACAACGCTCCGAATCGGTGCCCACGACATTGAGATCTCTCGAGGAACTCTCCAAGTATCCGCGGCCAAATTCTTTACAAATGTTCGGCGGTGAAGTTCGAATACTCGATAATACCGGCGAGACAAAAACTATGAGAATCGAGCCAAGACAAACGAATTCGCCGTCGAACGAGCATATAGTTAACAATAAATGCGTCACCACAGAGACATCATCGATTGTCGTACGCTCGGGACTTCATTCCGGTGGTACGATGGTTCATAAACCACCGGGAACTCCTGTAACCACTGGTAGCACACCAAATTCCTCCATATCTCTTCCGAACACTCCAAAGATGTTGGCACCAATTATACCTAACATATCAACGCCCAATTTAGCGCCCACGATGACGTGCTACAACTATTTGGAGCCTCATTTAAATCCCCTTACGAGCATCACTGCCTATAATCCTTTGACCCTTCAGCAAGCCGGTATTGCGAGCATCCTTCATGGTGGCAAGGTAATTCCCTATGTCCCGGGAATGCCTGGACCGCATACGCTCAGTGGACCCACGACTGTAGATATATCGCCGAATGTAGCGAGCGTTGACGCCGCTAACTCCAGTTACAAGGTTATTCCCGGTATTCCGGGTCTTCACATGATATCTCAACCTCTGGATCTCGCTAGTCCGGTCAGAGTTCAAACACCGAGCGTTCCTGGTATGCCCGGGCCGACTTCAAATAGCGCGTCACATCTAGGAGTGAATATCGGTCAACCTCTCGATCTCGCGAGTCCCGCCAAGGAAATCACGAAACTAAGCTTCAAAACTCCCACTAGCAGCGAGGCTATGCGGCAAGGATCTCTTCCGAGCCCAAAAGTTCCTAGCGTCAAGGTCGGCGACGCAACTACTACTACACCGTCGAGCAGCGAGAAATATAGGCTCGCCAGATCTTCCTCAACGCCGACCAGCGACTTGACCAAGGCTGAGTTGGATCGTCATATCAAGAATAATGTCGCAACTGCTGGCAAGTACAAGTTGAGCATTGATTGCTCGAGAGATAAGAAAGAATTGAATCACGAGAAGATCTCAAAAGTTGACACTATGTTGACTTACTCGAACGGTATTCACGTTTCGGACATTAACGCCTCGGCGAATTCTTACGGTAAACGATTTTCTCCAAAGGCAATGTCAGAAAGTGGCTGCAGAAAGAGACCGGCTAATTGGAGCATCGCCGAGATGGAGAATTCGCGAGTAAACGTCGATAATGTTCGTGATAGTCCGGTTATGAAGTACGACGTTTCCTCGCCTTCACCGACTTTCAATAATTCTCAAGAAAACGGACGCACGAGGATAAGCAGCTCTCCCGATTCAAAGTCTATGATTGTTGAGAACTACGGTGGAAATATCGCTAGTAGTGGTAAACAACGCGTCGATTCAGTGCCACCGGTAATCGTTATGAATCTAGATACTTCCAAGACAAATGTGCCAAACAAAACTTCCATGGAACTAGTTATCTTTAAGGCGGACAAGTCTGAATCTAGAACGCCAAAAATCAGCGAAATTGAGGAAACCCACGAGGAGGAGGAGACTAATACGAAATTCTTGAGACCCACGTCGTTGCCACTTAAACCGGGAACTTTTACGCCAAAACGTCATCACGGAATAACGCCGACGGCGAATACGCTGCCGCTTATTAGTCCTGAAACTCCGAGGCCAAAAAAATCTTACGGTCAGCTTTATCTCAACGGACACGCTTACACTTATTTGGGGTTGAAGTGCTCGACGAGAGTGTTTTATTGCACCCTCAACAGGCCGCAACCTATGTATGTTACGCAGCAACACGGTCTCTCCATGTACTCGAACTGGAAAATCTGCAAAGAAGCTCCACCGGATCTCGACATGGCGCATTATGACTCGAGACACAGGCCGCTTAGCTACACCGTTGCGTGGAAAAAGCAGGATGATATATTGACACATTCTTCGCAGCGTCCCAATACACCTACCAGTCCTGACAGCGGTCTTGAAAGTGACACTCAGGAGAAGACGCGAAGAGTCAAAATCTTTGATGGTGGCTTCGAGAGCAATGAGGATTACACCTACGTCAGGGGACGAGGTCGAGGTCGCTACGTCTGCGAGGAATGCGGTATACGTTGCAAAAAGCCTTCGATGCTGAAGAAACATATCAGAACTCACACGGATGTCAGGCCGTACACGTGCAAGCATTGTGCTTTTagCTTCAAAACGAAGGGCAATCTCACAAAACACATGAAGTCAAAGGCCCATTACAAGAAGTGCGTGGAGCTCGGAGTGATGCCCGTTCCGACTTCAGTTTGCGACGAAAACATTGACAAAGAGGCGATCGCTCGATTGGTAGCGGGAGGAGGAAACGCTGACGATTCGACAGACGAGGAGGACGAAACTGAGGGCGAGGAGAGTGACGAATCCGGAAGCGAGGAGCAAGAAGCTGCGCAGAGTCTCTTGAGTCTTTCGCAGCCAAGTCCCAACAGATTACCAGGACTTTTGCCTGCTGGTAGACCAACGACTTATCCTTATATTTTAACCTTGCCAACATCGTGCGTTACATCAACTACCACCAGCATCATATCTACGTCCGCGAGTACAGCTCCGATGAGCATCACTTCTACAACAGTGATTCAAAGTGAACTATCGCATCGTTACTATTTCCCATCGAGCCGTTCTTCCGTTGCTGACGAGTGCCGCGACAGTGTAATACGTTCGTCAAAAACCGAAGATTCTGATGTGGAGGTCGAAGAATTGGCTGAATCGGAGAGCAGACATCAACCTTCACAACCGATGGATCTCACGACAAAACAAATATCGCAGCCTCTACCTACGGCCATTATTCAAAGACCTATACCCGGTGACATACTAACTCCAGTCTCTGAGCCAATTCTCATGCAGACGATCGTTCAAACGATGGAGAGACTTCCTTTGCAGGGTCGAGAATGGAAACCTGACGCCGAAGGTCACATGCTTCAGGCTTATCTCACCGAAAGACACGTTATGGACAGCAAAATGAAGCAACAGTATCGCGTCGGAAATACTAAAAGGCAGGACCAACATCAGCAGATTAAAGATCGCGAAGCTTATCCAAAACAACTCGAATTCATGAGCTCAAGAAATATGGATTCGTGTAGTACACCGACAGTCACTTATACCGATCCCAGTAAACTACATCAGAGCATTCTCGAATCGAGAATCAAGTGCATGACGAAAATACAGACTTCCGAGGATATTAAGATGGAGATTCGAGAGAAAATTTATCAGAACAACGGCGTAATCGAGCGACGTCCTTTCGATATCGAGTCTCTTCATATTGATAAAGATTCGAACAATCATATGATTATGGAACGTGAGAATAACGCTGACAATCGACTTGTTGGTATTCCTGGCGCGAGAGTCAATAACGAACATCATTCTCTCACAATGGCGAAGCACCCGTCGAACGAGAGGCCGAACTTTAGTTGGGATTTTCCAAATCGTGCCGCTCCCGGACTTGATCGTCAGTCGCCTCAGACTTTTAATAATGATGTTAACAATCGACTTATGAGGTCTGAACAGACGATGAAAAATGAGATCGATCGCAGCACAATGTTCAACGCTATGAAAATGATGAGCGAAGTCGAACGACCTCGGGAATCCGTTAATCAAGATTTACGTAACGCTGGTCACGAAATTCAACCGCGCGAGGCTATAACGGACTCGAGGATAACACCGAGTCACAGCCCAAGGAATCAGGAGAATGGTACGGGAAACTCAAGACCACCGAGTCGAGAAATGAGAGGAACGAGCCAAGATTACAGGCCACAAGCGCCATCTTCTTCGCCTTCATTTCACGAGCCCAGACCATCTAGTCAAGAGTTCAAATTGCCGTGTCAAGAGCTGAGACCACCTAGTCAAGAATTTAAATCGCCGCATCAAGATCCACGAACCGGTCAGGAAGCTGTCGCACAACCTTCTGTCGTGCCCAGTGTCGTTGTCGACGTTCGTCATATCACAAACGATGCTAGGTCTCCCAGTAGGGATATGAGAATTATTCCCGAGTACAAAAACGAGCACAGGTCTCAGGAACTACCGCGTCAGAGCTACGACGTTGCACAATCGATGATACACGAATCCACAAAATTACATGATATTTCGAGAGGGCAACAAAATGAGACGAGAAACTCCGATCGTCTTGAAATCAAACGGCACGAAATGGAAATGACGAAGCACAGTATATCGGAAACTATCAAACACACTGTTGCGCGAAAAATGGTCGTTGGAGGACCTGGATTTCGATCTCCTTCACCACCCGGTGGCAGCGCTAAACCTCAGGCCGAATTCTTGCAACCTTCCAGCGGCCCCGCGTCGAATTACGTTAGCGTGACCGAGGACGGCCGAAGTGTTTGTGGGATCTGCAATAAGGTATTCAGCAAACCGAGTCAGTTGAGATTGCACATCAACATACATTACTTCGAACGGCCATTCCGATGCGAAAGCTGTGCTGTTTCCTTTAGAACGAAAGGTCACTTGACGAAACACGAGCGATCCGTCTCTCATCACAACAAGGTCAGTATGACGTCGACTTTCGGCGCGGCAACGACCAGCAACCCGCGACCGTTCAAGTGCACAGACTGCAAAATTGCCTTTCGGATACACGGTCATCTCGCCAAACATTTGCGCAGCAAAATGCACATTATGAAACTCGAGTGCCTCGGGAAATTACCGTTCGGCACTTATGCCGAGATGGAACGATCTGGCGTTAATCTCAACGACATAGACACCACCGACTGTGATAATAGTTTAACTAGTCTACAGATACTGGCTCAGAAGCTTTACGAGAAAGATCCCAGTAAAATGGGGCAGTGGGATGCGGAGATGGTACCGCATCAGGGAGCGAGTGGTGGCGAAACTTCGTCGGATGAAGGCGAGCCAATACCTCCTCATTCGATGCACCAATACCCAGCTCCACAAATGAATCCGGAGAGTGAAACTTCCCGAGCATATCACATGCCAATGTTAGTAGGGGATGAAACAAAGTCGATGAACGATGCGCATCTCGTTAATTTCCGGTTTCGGCAGCAACGTGCCGAATACAACAGATCAGAGAGACCCGGAAagcccatcgagtcggtcgatGATTCGAGGATGGACGAGATGTCGCATCCTTACAAGTGTCAAATTTGCACGGTCTCCGTGAGAACCGTTAATGAGCTACAAGTTCATTGCTTCGTCGAACACAATATCGAGTCTTCGGGAAATATCGGAAATTCACATCTCGGTGACGTACGAGACAAGGAAAATACTCAAAAGCGAATGTCCGAGGAAACGAGCGTCGTCGGTGACGACGTCCAAAGGAGACGGCAGAGCGACGATACATAG
- Protein Sequence
- MTDPQLTNNNNNNNNNNNNNNDGEPKYLHKKFKKMATTEAAPVENKQATTANTTGPSNDVPKKKDVGKDVKDVKESSRAEASPESEGEPTEARKAGYVCPYCKLSCAKPSVLQKHIRAHTNERPYPCVPCGFAFKTKSNLYKHCRSRAHALKMEGGDASKVSEDSDISLSDSASNGTGTPPPPPATSTPSSVPSTKTVKTGKIYKPKFHTALQCVNNEPEVSPVTSSSSNGSGATTTTTTTTTVATSLKPNAEQLQEHIDKIITDNQAIVEAVDPRLHKLMQRQQSLVEPKHTEQPLNLSSAEEASSRKRCYSESFAQENRGLVQNPEGSIIKDLLLKSRGINSDDTITTQESENLVCPSCKIPYTSADNLEAHRRYYCKGASPSPRRADFQLDLDKRDDYDNVKSSDYYGAIQPLPSPGPLLGNTRLVDAYTPPTKKQRSESVPTTLRSLEELSKYPRPNSLQMFGGEVRILDNTGETKTMRIEPRQTNSPSNEHIVNNKCVTTETSSIVVRSGLHSGGTMVHKPPGTPVTTGSTPNSSISLPNTPKMLAPIIPNISTPNLAPTMTCYNYLEPHLNPLTSITAYNPLTLQQAGIASILHGGKVIPYVPGMPGPHTLSGPTTVDISPNVASVDAANSSYKVIPGIPGLHMISQPLDLASPVRVQTPSVPGMPGPTSNSASHLGVNIGQPLDLASPAKEITKLSFKTPTSSEAMRQGSLPSPKVPSVKVGDATTTTPSSSEKYRLARSSSTPTSDLTKAELDRHIKNNVATAGKYKLSIDCSRDKKELNHEKISKVDTMLTYSNGIHVSDINASANSYGKRFSPKAMSESGCRKRPANWSIAEMENSRVNVDNVRDSPVMKYDVSSPSPTFNNSQENGRTRISSSPDSKSMIVENYGGNIASSGKQRVDSVPPVIVMNLDTSKTNVPNKTSMELVIFKADKSESRTPKISEIEETHEEEETNTKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPKKSYGQLYLNGHAYTYLGLKCSTRVFYCTLNRPQPMYVTQQHGLSMYSNWKICKEAPPDLDMAHYDSRHRPLSYTVAWKKQDDILTHSSQRPNTPTSPDSGLESDTQEKTRRVKIFDGGFESNEDYTYVRGRGRGRYVCEECGIRCKKPSMLKKHIRTHTDVRPYTCKHCAFSFKTKGNLTKHMKSKAHYKKCVELGVMPVPTSVCDENIDKEAIARLVAGGGNADDSTDEEDETEGEESDESGSEEQEAAQSLLSLSQPSPNRLPGLLPAGRPTTYPYILTLPTSCVTSTTTSIISTSASTAPMSITSTTVIQSELSHRYYFPSSRSSVADECRDSVIRSSKTEDSDVEVEELAESESRHQPSQPMDLTTKQISQPLPTAIIQRPIPGDILTPVSEPILMQTIVQTMERLPLQGREWKPDAEGHMLQAYLTERHVMDSKMKQQYRVGNTKRQDQHQQIKDREAYPKQLEFMSSRNMDSCSTPTVTYTDPSKLHQSILESRIKCMTKIQTSEDIKMEIREKIYQNNGVIERRPFDIESLHIDKDSNNHMIMERENNADNRLVGIPGARVNNEHHSLTMAKHPSNERPNFSWDFPNRAAPGLDRQSPQTFNNDVNNRLMRSEQTMKNEIDRSTMFNAMKMMSEVERPRESVNQDLRNAGHEIQPREAITDSRITPSHSPRNQENGTGNSRPPSREMRGTSQDYRPQAPSSSPSFHEPRPSSQEFKLPCQELRPPSQEFKSPHQDPRTGQEAVAQPSVVPSVVVDVRHITNDARSPSRDMRIIPEYKNEHRSQELPRQSYDVAQSMIHESTKLHDISRGQQNETRNSDRLEIKRHEMEMTKHSISETIKHTVARKMVVGGPGFRSPSPPGGSAKPQAEFLQPSSGPASNYVSVTEDGRSVCGICNKVFSKPSQLRLHINIHYFERPFRCESCAVSFRTKGHLTKHERSVSHHNKVSMTSTFGAATTSNPRPFKCTDCKIAFRIHGHLAKHLRSKMHIMKLECLGKLPFGTYAEMERSGVNLNDIDTTDCDNSLTSLQILAQKLYEKDPSKMGQWDAEMVPHQGASGGETSSDEGEPIPPHSMHQYPAPQMNPESETSRAYHMPMLVGDETKSMNDAHLVNFRFRQQRAEYNRSERPGKPIESVDDSRMDEMSHPYKCQICTVSVRTVNELQVHCFVEHNIESSGNIGNSHLGDVRDKENTQKRMSEETSVVGDDVQRRRQSDDT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00414563;
- 90% Identity
- -
- 80% Identity
- -