Eman006884.1
Basic Information
- Insect
- Ephialtes manifestator
- Gene Symbol
- topi_2
- Assembly
- GCA_963970395.1
- Location
- OZ019968.1:45834640-45836809[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 8.3e-05 0.016 17.1 1.2 1 23 168 190 168 190 0.98 2 9 1.8e-06 0.00034 22.3 1.3 1 23 196 219 196 219 0.98 3 9 0.018 3.4 9.7 4.3 1 23 226 249 226 249 0.94 4 9 4e-05 0.0076 18.0 2.3 1 23 255 277 255 277 0.98 5 9 0.0021 0.41 12.6 0.2 3 23 284 305 282 305 0.94 6 9 5.9e-06 0.0011 20.7 3.3 1 23 312 334 312 334 0.98 7 9 1.6e-06 0.00031 22.4 0.4 1 23 338 360 338 360 0.98 8 9 0.011 2.1 10.4 1.4 3 23 367 387 365 387 0.96 9 9 1e-05 0.002 19.9 0.6 1 23 393 416 393 416 0.97
Sequence Information
- Coding Sequence
- ATGTTGAAGCACATGGAAATTCAAGTACAAATGCCCACGACGTTACCCATATCTCAAGAAAAGAAGAGCGGTCGTCGTAAGAAGAGCGTTCCGGCAAGTAGAGCAAAGGAAAATGATAAGGAGAAGAAGCCAACAACAGCCGTGGCAGTACAAATCAAAGAGGAAGTCCAGCCTTCGGAGCAGCCGTCCAGGTTAAAATCGGTGCGATCCAAGCGAAAAGTTGAACCTATCAAGGCCGAAGAAAGTGTTCCACCGAAGAAGCGAAAATTGGGCCGACGATTGTCAACGAAGGCTCCAATCAAGAGAAACTTCATATTTACCAGCGATTCCGATGATGTCGACGAGAGTTCGCACGACTACTGGAGAAACTCCGACGAAGAGCCGCCGGTACGTGTCGAGATCAAAGAAGTGAAGAAGGAGGTTGACGACAGCTCCAACGACTACTGGCGCGATTCCGACGAGGACGGCGGAAAACCTGTCGAGTTCAAAACAAACACAGGCTATGAATGTTCAGCCTGCGAGATGACTTTCACAGTTCGTCGAAAGCTCAACAAGCACATGCTAAAGCACAACAATCAGAAGCCATACGAGTGCCCGACgtgccaaaaaaaattcaagtacagtGTCGGTcttaaaaatcatattaaatCGCAGCACAGCGAAGACGCGCCTTGTTTTACCTGCGAAATGTGCGACTTCACGACCAAACAAGAGCACTACCTTCAGGAACACTTCACGAGGAAACACACCGAAGAGTACAGATACCAATGCAGCTTGTGCGGCAAACACTTCAAGGCCGAGCGCGACTACAAGGCTCACATGAGTAATCACGATACCGGACCGCAAATCTGCGATATTTGCGGCGTCACATATCCCAACAAGATCTCACTGTACTCTCACAAGAATTACAAACACACGGAGAAGGACAAGCCCTTCGAGTGTGAGATTTGCAAGAAACGACTACGAACTCAGAAGAATCTTGAGAATCATATGCAGCATCATAATCAAACCTACGTGTGCGAGGAGTGCGGCATGAAATTTGCCAGGCAGACCGGCTTATCCAAACACCGTAAAATACACAGAGAGAAATCCTGTCTCTGTCCCGTCTGCGGAAAAGCCTTCGCCTGTATGACTACCGTTAGGGTCCACATGATCACTCACTCCGGCGACAGACCCTACATTTGTGACGTCTGCGGCAACAGCTACACTCAGAGATCCTCGCTGATGCTCCACTGGAGGAAGAAACATCCCGAAGCCAGCCAACCACCGCCCCCCGTTACGCTCAAAAACATTCCCGAGACTATGAAGGCCGACGCTGACTGA
- Protein Sequence
- MLKHMEIQVQMPTTLPISQEKKSGRRKKSVPASRAKENDKEKKPTTAVAVQIKEEVQPSEQPSRLKSVRSKRKVEPIKAEESVPPKKRKLGRRLSTKAPIKRNFIFTSDSDDVDESSHDYWRNSDEEPPVRVEIKEVKKEVDDSSNDYWRDSDEDGGKPVEFKTNTGYECSACEMTFTVRRKLNKHMLKHNNQKPYECPTCQKKFKYSVGLKNHIKSQHSEDAPCFTCEMCDFTTKQEHYLQEHFTRKHTEEYRYQCSLCGKHFKAERDYKAHMSNHDTGPQICDICGVTYPNKISLYSHKNYKHTEKDKPFECEICKKRLRTQKNLENHMQHHNQTYVCEECGMKFARQTGLSKHRKIHREKSCLCPVCGKAFACMTTVRVHMITHSGDRPYICDVCGNSYTQRSSLMLHWRKKHPEASQPPPPVTLKNIPETMKADAD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01497687;
- 90% Identity
- iTF_01497687;
- 80% Identity
- -