Eman036918.1
Basic Information
- Insect
- Ephialtes manifestator
- Gene Symbol
- -
- Assembly
- GCA_963970395.1
- Location
- OZ019978.1:27344443-27347225[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 1.4e-05 0.0027 19.5 3.0 1 23 332 354 332 354 0.98 2 12 0.013 2.5 10.1 3.9 1 23 358 380 358 380 0.98 3 12 0.0046 0.86 11.6 6.4 1 23 385 407 385 407 0.96 4 12 1.9e-05 0.0037 19.0 2.8 1 23 458 480 458 480 0.98 5 12 0.00095 0.18 13.7 1.4 1 23 485 507 485 507 0.97 6 12 0.00012 0.023 16.6 2.2 1 23 556 578 556 578 0.98 7 12 0.00036 0.069 15.0 0.7 2 23 586 607 585 607 0.97 8 12 1.2e-06 0.00022 22.9 2.1 1 23 618 640 618 640 0.96 9 12 7.4e-05 0.014 17.2 1.0 1 23 646 668 646 668 0.98 10 12 0.00019 0.036 15.9 0.7 1 23 674 696 674 696 0.98 11 12 5.7e-06 0.0011 20.7 2.0 1 23 702 724 702 724 0.96 12 12 0.0001 0.019 16.8 0.3 1 22 730 751 730 751 0.96
Sequence Information
- Coding Sequence
- ATGGCCATGAATACAAACTACTTTGTGCCACCAGTAAATCTCGACAGAGTTTGCAGGGTGTGTTTGCTGGAAGGTGATAATTTGGCGCCGATATTTTCATCCGACCAAGAAGTCGACGATTATGCTGGTCTTTCTCAAAAGATTCAAGTATGCGGATCGATTGAGATACACGAGAACGACGGATTTCCCTCTCTCATATGCAACGTTTGCGTCTACAAAGCCAGCATAGCTCACGAATTTAGACAACAATGCCAGCAATCCGATACTCGTTTAAGGCTTTTGTATGATAAACCCGCGCGGTCTAACATTGCCGAATCTTGCACACAGACTGATCCCCAGACGCGTATAATCCTAACGCGAAAAGTGCCTACGCCTCCAACGACATATTTTGTGAAGCAAGAATTGCAGCAATCAGCGCAGCAAGATTACGTGAGCGCAATCGAGGCTTACACGGAAAATCACGAGCCTGTTCGTGAGGAACACACGATAGATTGTCAGGATGAGAAGCTTTTTCTCTGCAACATCGGGTTCGAGGGCACGAAAGAAATAACCGACAAAGAAGCGAGTATTTTGACTCACCAGGCGCATCAAGTTAATTGTCCTCAGGAACACACGGAGCTAACAACGACATTGATAACTGTAAACGCGAATGGCCAATTGGAGCAGCAGGAACTGATTGTCAAAGAGGACGGTGGAAAATGCAACGAAACGGAAATGGAAGAGGAATATCTTAACGAACAATTGTTGAACGAGAGCGTTGAACAAACCGTTGAAGAGGAGCAGCAACATCTGGAAACTCACGAGGTTCACGAAACACACGAGGAACTCGTGGAACATCAGCAACAGGATAAAGAACAGCCTCAACCAACGAGAACATCATCGAGAAAGGCAAAAACAACAACTGGCAAATCTTACAGCGAGGAGGACGAGATTCTCGATGATGATTACTTCGAAGGTTTAGTCAGCGACAGTCAAGACTCCGAGGGACCAAAATTTAAGTGTGACATATGCTCCAAGTGCTACACAACGCAAAAAGGACTGAAAAATCATGCACAGGTTCACGATAAAAATCACAAATGTCCGGTTTGTTTTAAGCTATTTTTCAAgttaaaaaatatggaaaatcatcgaaaaattcACGACGCGAAGCCTCATGCTTGTAGAGTTTGTCACGCTTGTTTCTCAAAGTCTCAGAGCCTCGTTCGTCATCTCAAGTCTCACACGGAAAAGGATATTACGAAACAGGCTATGACTGATGATTTTAAGGAAGACGAGACTGAAACTAAGCATGATACGAAAAGCGACGGCGACAGTGACGACGAAACGGGCGCCAATAACGATATTGACGAATTCGATAATGCTCCGGGTCTTTACAAGTGCGAAGTTTGCGGACAATTTTGCTCCTCGCTGAAAAATCTTAAGAGACACACTCTCGTTCATGGTGACAAAAAGTACTCTTGTACTGTATGCAAAAAGTGGTTTTTCCGACCTGACACGCTGAAGAAACATGCGGAAAAGCACGGACACGGTTTGCTGGACAATCTAATAGACGATAATAAACTTTTTGATTCCGACGACGATTCTTTTCCGAATACTGGTGGTAATCCGTCGTTAGGCAACGAAACTGGAAAGAGAGACGAGAGCGACGAGGACGGCGTTGGCGAGTACAAATGTCAGCACTGCGACAAAGTAATGGCAACGAAAAAAGGACTCCGAAGACACGTTTCGATGCACAAACCGAAAGCCGAGCCGGTTACTTgtgaaatatgtaaaaaagttTGCGCTAGCCAAGCGCGTTTGGCGCTGCATCTTAAGACACACAACAAACCAAAGGAAAAAGTACAGAGGGAGTATCTTTGTCATATCTGCAGCAAAGTTTATCCAAGCAACTCGTCGCTTACTTATCATATGCGAACTCACACGGGCGTTAAACCGCacgtttgtaaaatttgtaacagCGGTTTTACAACCACCACGAGTTTAGCCAATCATATTCGCATTCACACGGGCGATAAGCCTTTTGTTTGTCACGTTTGCAGCGCTGCGTTCGCCGTTAGTTCGGCTTTTAGGCGCCACCTTACGAGACACACGGGCGAGGCGAATTATCTTTGCAAAACTTGCGGAAAAGCCTTTAAGAGACTGAGCACATTGAAGGAACACACTTATACGCACTCGGGCGAGAAGCCATATGTTTGCAAAACTTGCGGCGCTGCTTATAGTCACAGCGGGAGTCTTTTTGCACATCAGAAAAGATGTAGAGTGCAGTATGGTGAAATGGTCGAGGAACACGCTGTTGCTCATCATATTCATGTTAGCAACGTGCAAACTGCTGTTAGATCGCTTGCAGTTATTGGACAGATGTACTAG
- Protein Sequence
- MAMNTNYFVPPVNLDRVCRVCLLEGDNLAPIFSSDQEVDDYAGLSQKIQVCGSIEIHENDGFPSLICNVCVYKASIAHEFRQQCQQSDTRLRLLYDKPARSNIAESCTQTDPQTRIILTRKVPTPPTTYFVKQELQQSAQQDYVSAIEAYTENHEPVREEHTIDCQDEKLFLCNIGFEGTKEITDKEASILTHQAHQVNCPQEHTELTTTLITVNANGQLEQQELIVKEDGGKCNETEMEEEYLNEQLLNESVEQTVEEEQQHLETHEVHETHEELVEHQQQDKEQPQPTRTSSRKAKTTTGKSYSEEDEILDDDYFEGLVSDSQDSEGPKFKCDICSKCYTTQKGLKNHAQVHDKNHKCPVCFKLFFKLKNMENHRKIHDAKPHACRVCHACFSKSQSLVRHLKSHTEKDITKQAMTDDFKEDETETKHDTKSDGDSDDETGANNDIDEFDNAPGLYKCEVCGQFCSSLKNLKRHTLVHGDKKYSCTVCKKWFFRPDTLKKHAEKHGHGLLDNLIDDNKLFDSDDDSFPNTGGNPSLGNETGKRDESDEDGVGEYKCQHCDKVMATKKGLRRHVSMHKPKAEPVTCEICKKVCASQARLALHLKTHNKPKEKVQREYLCHICSKVYPSNSSLTYHMRTHTGVKPHVCKICNSGFTTTTSLANHIRIHTGDKPFVCHVCSAAFAVSSAFRRHLTRHTGEANYLCKTCGKAFKRLSTLKEHTYTHSGEKPYVCKTCGAAYSHSGSLFAHQKRCRVQYGEMVEEHAVAHHIHVSNVQTAVRSLAVIGQMY
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01497651;
- 90% Identity
- iTF_00343356;
- 80% Identity
- -