Edan008986.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ephemera danica
Gene Symbol
-
Assembly
GCA_000507165.2
Location
KZ498104.1:5810-27170[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1.3 89 3.9 2.6 2 23 358 380 357 380 0.95
2 16 0.24 16 6.2 2.8 1 21 383 403 383 407 0.91
3 16 0.54 37 5.1 0.3 3 12 411 420 410 431 0.79
4 16 0.069 4.6 7.9 5.0 1 23 480 502 480 502 0.98
5 16 1.1 72 4.1 7.8 3 23 507 528 505 528 0.90
6 16 5 3.4e+02 2.0 0.9 2 23 547 569 546 569 0.85
7 16 0.0084 0.57 10.8 0.7 1 23 603 626 603 626 0.95
8 16 8.2e-05 0.0055 17.1 1.8 1 23 633 656 633 656 0.97
9 16 0.11 7.2 7.3 0.9 1 23 694 717 694 717 0.92
10 16 0.13 8.7 7.0 0.2 2 23 723 744 722 744 0.92
11 16 2.6 1.8e+02 2.9 2.3 1 19 750 768 750 773 0.84
12 16 0.92 62 4.4 3.0 1 20 791 810 791 812 0.94
13 16 0.88 59 4.4 0.1 3 22 825 843 823 845 0.80
14 16 0.0034 0.23 12.0 1.9 2 23 852 874 851 874 0.94
15 16 0.0071 0.48 11.0 0.7 3 23 883 904 881 904 0.90
16 16 8.3e-07 5.6e-05 23.4 0.4 1 23 911 933 911 933 0.98

Sequence Information

Coding Sequence
ATGGCTTTGAAGCGGAAAAAAGTGGCACCTCCACTGTTCTACGACGTAGAATCCAACACTTTGTATCCTGAAGGGTTTGGCCCAAAAAAGAGAAAATGTGACGATGTGTGTAGAATTTGTGCAGAGCGTGACACTTTAATAGGATCCAATGAGTTGATAGACATGTATGGAGAGCATGGGAAAAGTTTAAGCTTATCTGCACAAGTCAACAGATTTCTCCCTATTGAGGTTAAGGAATCCGATGGTCTCTCACACTGGATCTGCCTTCACTGTAGAACCATTCTACTCAAGATGGACAACTTGTACTCAATTTGCCAGAAGACTGATGCATATTTCACTGAACAAATGCATGGTGTAGAACCTATTGAAACAGAAATGGTCGagGTTAAGGAATCCGATGGTCTCTCACACTGGATCTGCCTTCACTGTAGAACCATTCTACTCAAGATGGACAACTTGTACTCAATTTGCGAGAAGACTGATGCATATTTCACTGAACAAATGCACGGTGTAGAACCTATTGAAACAGAAATGGTCGaggAATTTGATGCTGCTTGTGAAGACCTGATTGTTGAAACATCTCACAATTTTGAAGAAACTTCACCTACTGAACCTGATACCTCCAAGACAGGTAACATTGGTTTCACTGTTTTTGTGGAGGAACCAATTTTTCAAACACATAGTTTTAGTTTTGGTAATAACGAAGAATTGAACATCAACTTAAAGCTGCCAACTTCTGAACCTGAAATATACAGTTTTAGCATTACCGAAGAAGAATCGACTGTTGAAATTTCTAATTTGGTTGATAATGAAAAATTGAGCAACTCAGAGTTACCAACTTTTGAGCATGACAATTCTGACGATTTGATAACAGAAGATTTCGTGTCTGATATTTCTGATCCAGAAGAAGAAATTCTGACAGTGACTACAACAAAATCAAATTCTGCCATACCAACTGCAACTAAAGTAAAGAACATCCGACCAACCGCTACTAAAAGTAAGACCAAGAGTGCCAAACCAACTAAgactaaaagaaaaaatacaaaagcagGAAAGTCATGCAAAATCAATAGATGTGACTTATGTGGTGATATGTGCATGtctataaaacaatttaagaCACATATGAAAGAACAACACCAAAAATTTGTGTGTTATAAATGTTTAGCTACATTTGATGATCACTCTGATTATAAAGAACATTTGCACCAAGAAAATCAtggtaaaatatgtaatatatgtaataaaGAATTCAATGATGTGAACAAAGGAAAAAGTCATGCTAGTCTACATTACATACCTGTCAAAGTAGTGATTTCCACTGGAAAAGAAAACCATAAAACAGTGGAGACCACAGGTGTACCTGTTGAAATCAATGAATTGGTAATTCCAattcaaaacaatgaaaacatcTCAAATACGTCCAAAACATTCCCATTTCAGTGTCATTTTTGTAACAAGGAAATAAGCAATTCAACTGAAGCTACTCATCATTACAAAGAACACGAAATGCATCTCTGCTCTTTCTGCTTCAATCATTTCCCTAATaggaaGTCACTTAGAAGGCATATGGTTCACAAGCATCCCAAGAAAGTTTCAGAATTCAATAAACAAcacaatataaacaaacaagCTCTAACTTGTACAATATGCTTTAAAGAATAtcttacattattttcaatcaaaaacCATTATTTGGAATtccatcaaaaatatttttgctgtccTTGTAAATTACTGTTTGACACTCCTCAAGAACTTGACACTCATAGTTTGGAAGTTCACAGCTGCAATGCTTCTTTCTCTCATCAATGTTCTGCCTGTGGAAAAAACTTTGAGTCAGAAGAGAGCCTGGCGTTTCACATGAAAAATGGTCATGAGAATCCTGCTAAAAGATATTATTGTGATAAATGTGCAAAATCTTATGTTCATAAAGATACTTTAAAAGAGCATATTTTGAAagttcatgaaaaaatcattcTAAAAGGTGATGTAAAAGTTCTATGTGAATTCTGTAATAAATATATGGCAGCTAAGAGaattgaaaaacataaaatatctcATAAAGATGATAAACAGTTTATTTGTATTCATTGTGATGCAACATTCCCCAGTgtctataaattacaaattcatttccaatcGAATCATGAGGTAAATGTGGTTAAATGCCCGGAATGTCAAATACAATtggataaaaatgaattgaaaaaacatTTAGAAGAAGAGCATACTACAGAATGGacttatatttgtaaaaaatgtaacttaaattACAAAACAGACACTGAAATATGGCAACATTGTACCACGGAACATGGTATAAAACAAGATCCAACTTCACTTATTCCATACCTTCGCACATCACCTCATCAATGTAAAATCTGTTTTGAGTATCTTGCAAATGctttcaagttaaaaaaacataaacacaaCATTCGTACTCATTCAAATTCAGCAGTGAAAGTCATTTGTGATTTATGTGGTGAAGCTTATAGTAAATATTCTAAAGCAAGTCATATGTATGCAAAACACAATAAACCACTTCCAAATCAATGTAATGTTTGTGGTCGTAGTTTtaaatcactgaaaaaaaaaattaatcatgtgTCTAAATTTCACGATGATgaaaaacgaaaaataatttgtgaaatttGTAAACTTTGTTTTCCAAATCTAAGAAATATGCTCCGTCATAAGAGTGCAATTCACGGAAAGTGTATAAAATTGTTTCCATGCCCATACTGCCCCCaaaagttgaaacaaaaatCTAGTTTACAAGATCACATGAGAGTGCATGCAGCAAATATACCGTATCGA
Protein Sequence
MALKRKKVAPPLFYDVESNTLYPEGFGPKKRKCDDVCRICAERDTLIGSNELIDMYGEHGKSLSLSAQVNRFLPIEVKESDGLSHWICLHCRTILLKMDNLYSICQKTDAYFTEQMHGVEPIETEMVEVKESDGLSHWICLHCRTILLKMDNLYSICEKTDAYFTEQMHGVEPIETEMVEEFDAACEDLIVETSHNFEETSPTEPDTSKTGNIGFTVFVEEPIFQTHSFSFGNNEELNINLKLPTSEPEIYSFSITEEESTVEISNLVDNEKLSNSELPTFEHDNSDDLITEDFVSDISDPEEEILTVTTTKSNSAIPTATKVKNIRPTATKSKTKSAKPTKTKRKNTKAGKSCKINRCDLCGDMCMSIKQFKTHMKEQHQKFVCYKCLATFDDHSDYKEHLHQENHGKICNICNKEFNDVNKGKSHASLHYIPVKVVISTGKENHKTVETTGVPVEINELVIPIQNNENISNTSKTFPFQCHFCNKEISNSTEATHHYKEHEMHLCSFCFNHFPNRKSLRRHMVHKHPKKVSEFNKQHNINKQALTCTICFKEYLTLFSIKNHYLEFHQKYFCCPCKLLFDTPQELDTHSLEVHSCNASFSHQCSACGKNFESEESLAFHMKNGHENPAKRYYCDKCAKSYVHKDTLKEHILKVHEKIILKGDVKVLCEFCNKYMAAKRIEKHKISHKDDKQFICIHCDATFPSVYKLQIHFQSNHEVNVVKCPECQIQLDKNELKKHLEEEHTTEWTYICKKCNLNYKTDTEIWQHCTTEHGIKQDPTSLIPYLRTSPHQCKICFEYLANAFKLKKHKHNIRTHSNSAVKVICDLCGEAYSKYSKASHMYAKHNKPLPNQCNVCGRSFKSLKKKINHVSKFHDDEKRKIICEICKLCFPNLRNMLRHKSAIHGKCIKLFPCPYCPQKLKQKSSLQDHMRVHAANIPYR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-